FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8650, 330 aa
  1>>>pF1KB8650 330 - 330 aa - 330 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.9171+/-0.00101; mu= -5.1310+/- 0.061
 mean_var=264.8197+/-57.665, 0's: 0 Z-trim(113.4): 117  B-trim: 4 in 1/52
 Lambda= 0.078813
 statistics sampled from 13927 (14046) to 13927 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.766), E-opt: 0.2 (0.431), width:  16
 Scan time:  2.490

The best scores are:                                      opt bits E(32554)
CCDS13999.1 GRAP2 gene_id:9402|Hs108|chr22         ( 330) 2306 275.0 5.7e-74
CCDS11721.1 GRB2 gene_id:2885|Hs108|chr17          ( 217)  570 77.5 1.1e-14
CCDS11202.1 GRAP gene_id:10750|Hs108|chr17         ( 217)  542 74.3 9.9e-14


>>CCDS13999.1 GRAP2 gene_id:9402|Hs108|chr22              (330 aa)
 initn: 2306 init1: 2306 opt: 2306  Z-score: 1441.4  bits: 275.0 E(32554): 5.7e-74
Smith-Waterman score: 2306; 100.0% identity (100.0% similar) in 330 aa overlap (1-330:1-330)

               10        20        30        40        50        60
pF1KB8 MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFIDIQFPKWFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFIDIQFPKWFH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 EGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFLWTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 EGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFLWTE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 KFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQGHRGNSLDRRSQGGPHLSGAVGEEIRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 KFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQGHRGNSLDRRSQGGPHLSGAVGEEIRP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 SMNRKLSDHPPTLPLQQHQHQPQPPQYAPAPQQLQQPPQQRYLQHHHFHQERRGGSLDIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 SMNRKLSDHPPTLPLQQHQHQPQPPQYAPAPQQLQQPPQQRYLQHHHFHQERRGGSLDIN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 DGHCGTGLGSEMNAALMHRRHTDPVQLQAAGRVRWARALYDFEALEDDELGFHSGEVVEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 DGHCGTGLGSEMNAALMHRRHTDPVQLQAAGRVRWARALYDFEALEDDELGFHSGEVVEV
              250       260       270       280       290       300

              310       320       330
pF1KB8 LDSSNPSWWTGRLHNKLGLFPANYVAPMTR
       ::::::::::::::::::::::::::::::
CCDS13 LDSSNPSWWTGRLHNKLGLFPANYVAPMTR
              310       320       330

>>CCDS11721.1 GRB2 gene_id:2885|Hs108|chr17               (217 aa)
 initn: 763 init1: 328 opt: 570  Z-score: 377.2  bits: 77.5 E(32554): 1.1e-14
Smith-Waterman score: 578; 33.9% identity (54.1% similar) in 333 aa overlap (1-330:1-215)

               10        20        30          40        50        
pF1KB8 MEAVAKFDFTASGEDELSFHTGDVLKILSNQ--EEWFKAELGSQEGYVPKNFIDIQFPKW
       :::.::.:: :...:::::. ::.::.:...  ..:.::::....:..:::.:...   :
CCDS11 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
               10        20        30        40        50        60

       60        70         80        90       100       110       
pF1KB8 FHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFL
       :   . : .::..:   .. : :.:: :.:.:::::.::.  .:::::::.::. :.:::
CCDS11 FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KB8 WTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQGHRGNSLDRRSQGGPHLSGAVGEE
       :. :: :::.::::.:..:.::..::::::                              
CCDS11 WVVKFNSLNELVDYHRSTSVSRNQQIFLRD------------------------------
              130       140       150                              

       180       190       200       210       220       230       
pF1KB8 IRPSMNRKLSDHPPTLPLQQHQHQPQPPQYAPAPQQLQQPPQQRYLQHHHFHQERRGGSL
                                           ..: :::                 
CCDS11 ------------------------------------IEQVPQQ-----------------
                                                                   

       240       250       260       270       280       290       
pF1KB8 DINDGHCGTGLGSEMNAALMHRRHTDPVQLQAAGRVRWARALYDFEALEDDELGFHSGEV
                                 :. .::         :.::.  :: ::::. :. 
CCDS11 --------------------------PTYVQA---------LFDFDPQEDGELGFRRGDF
                                 160                170       180  

       300       310       320       330  
pF1KB8 VEVLDSSNPSWWTGRLHNKLGLFPANYVAPMTR  
       ..:.:.:.:.:: :  :.. :.:: :::.:..:  
CCDS11 IHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
            190       200       210       

>>CCDS11202.1 GRAP gene_id:10750|Hs108|chr17              (217 aa)
 initn: 676 init1: 326 opt: 542  Z-score: 360.0  bits: 74.3 E(32554): 9.9e-14
Smith-Waterman score: 542; 52.7% identity (82.0% similar) in 150 aa overlap (1-147:1-150)

               10        20        30          40        50        
pF1KB8 MEAVAKFDFTASGEDELSFHTGDVLKILSNQEE--WFKAELGSQEGYVPKNFIDIQFPKW
       ::.:: ..: :.  :::.:. ::.::::. ...  :.:::: . ::..:::.: ..   :
CCDS11 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW
               10        20        30        40        50        60

       60        70         80        90       100       110       
pF1KB8 FHEGLSRHQAENLLMGKE-VGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFL
       .   .::. ::..:: .. .: :.:: :.::::.::.:: . :.::::::.:. .:.:::
CCDS11 YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFL
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KB8 WTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQGHRGNSLDRRSQGGPHLSGAVGEE
       : ::: :::.:::.:::..:....::::::                              
CCDS11 WEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQDPSQLSFR
              130       140       150       160       170       180




330 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 14:09:16 2016 done: Fri Nov  4 14:09:17 2016
 Total Scan time:  2.490 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]