FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8651, 486 aa 1>>>pF1KB8651 486 - 486 aa - 486 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.9479+/-0.000539; mu= -2.2810+/- 0.033 mean_var=357.8457+/-76.749, 0's: 0 Z-trim(116.8): 90 B-trim: 41 in 1/58 Lambda= 0.067799 statistics sampled from 28234 (28318) to 28234 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.332), width: 16 Scan time: 8.840 The best scores are: opt bits E(85289) NP_001171899 (OMIM: 604960) protein kinase C and c ( 486) 3270 334.3 4.6e-91 NP_009160 (OMIM: 604960) protein kinase C and case ( 486) 3270 334.3 4.6e-91 XP_016884053 (OMIM: 604960) PREDICTED: protein kin ( 486) 3270 334.3 4.6e-91 XP_011528151 (OMIM: 604960) PREDICTED: protein kin ( 488) 3256 333.0 1.2e-90 XP_011528153 (OMIM: 604960) PREDICTED: protein kin ( 488) 3256 333.0 1.2e-90 XP_016884051 (OMIM: 604960) PREDICTED: protein kin ( 488) 3256 333.0 1.2e-90 XP_016884052 (OMIM: 604960) PREDICTED: protein kin ( 488) 3256 333.0 1.2e-90 XP_011528152 (OMIM: 604960) PREDICTED: protein kin ( 488) 3256 333.0 1.2e-90 XP_011528150 (OMIM: 604960) PREDICTED: protein kin ( 488) 3256 333.0 1.2e-90 XP_011528148 (OMIM: 604960) PREDICTED: protein kin ( 488) 3256 333.0 1.2e-90 XP_011528149 (OMIM: 604960) PREDICTED: protein kin ( 488) 3256 333.0 1.2e-90 XP_011528154 (OMIM: 604960) PREDICTED: protein kin ( 447) 2978 305.7 1.7e-82 NP_001171900 (OMIM: 604960) protein kinase C and c ( 445) 2340 243.3 1e-63 XP_005261376 (OMIM: 604960) PREDICTED: protein kin ( 445) 2340 243.3 1e-63 XP_016884054 (OMIM: 604960) PREDICTED: protein kin ( 447) 2326 242.0 2.7e-63 XP_016884055 (OMIM: 604960) PREDICTED: protein kin ( 447) 2326 242.0 2.7e-63 XP_016884056 (OMIM: 604960) PREDICTED: protein kin ( 447) 2326 242.0 2.7e-63 XP_011528155 (OMIM: 604960) PREDICTED: protein kin ( 447) 2326 242.0 2.7e-63 XP_016884057 (OMIM: 604960) PREDICTED: protein kin ( 406) 2048 214.7 3.9e-55 NP_065855 (OMIM: 606512) protein kinase C and case ( 444) 1690 179.7 1.4e-44 NP_001186512 (OMIM: 606512) protein kinase C and c ( 444) 1690 179.7 1.4e-44 XP_011512843 (OMIM: 606512) PREDICTED: protein kin ( 444) 1690 179.7 1.4e-44 NP_001171903 (OMIM: 606513) protein kinase C and c ( 424) 1407 152.0 3e-36 NP_057307 (OMIM: 606513) protein kinase C and case ( 424) 1407 152.0 3e-36 NP_001171904 (OMIM: 606513) protein kinase C and c ( 424) 1407 152.0 3e-36 >>NP_001171899 (OMIM: 604960) protein kinase C and casei (486 aa) initn: 3270 init1: 3270 opt: 3270 Z-score: 1755.9 bits: 334.3 E(85289): 4.6e-91 Smith-Waterman score: 3270; 100.0% identity (100.0% similar) in 486 aa overlap (1-486:1-486) 10 20 30 40 50 60 pF1KB8 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 FEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 YNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNPFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNPFD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPAN 430 440 450 460 470 480 pF1KB8 YVEAIQ :::::: NP_001 YVEAIQ >>NP_009160 (OMIM: 604960) protein kinase C and casein k (486 aa) initn: 3270 init1: 3270 opt: 3270 Z-score: 1755.9 bits: 334.3 E(85289): 4.6e-91 Smith-Waterman score: 3270; 100.0% identity (100.0% similar) in 486 aa overlap (1-486:1-486) 10 20 30 40 50 60 pF1KB8 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 FEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 FEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 YNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNPFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 YNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNPFD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 DDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPAN 430 440 450 460 470 480 pF1KB8 YVEAIQ :::::: NP_009 YVEAIQ >>XP_016884053 (OMIM: 604960) PREDICTED: protein kinase (486 aa) initn: 3270 init1: 3270 opt: 3270 Z-score: 1755.9 bits: 334.3 E(85289): 4.6e-91 Smith-Waterman score: 3270; 100.0% identity (100.0% similar) in 486 aa overlap (1-486:1-486) 10 20 30 40 50 60 pF1KB8 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 FEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 YNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNPFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNPFD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPAN 430 440 450 460 470 480 pF1KB8 YVEAIQ :::::: XP_016 YVEAIQ >>XP_011528151 (OMIM: 604960) PREDICTED: protein kinase (488 aa) initn: 2098 init1: 2044 opt: 3256 Z-score: 1748.5 bits: 333.0 E(85289): 1.2e-90 Smith-Waterman score: 3256; 99.6% identity (99.6% similar) in 488 aa overlap (1-486:1-488) 10 20 30 40 50 60 pF1KB8 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 FE--EWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQ :: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEDEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 SSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYP 430 440 450 460 470 480 480 pF1KB8 ANYVEAIQ :::::::: XP_011 ANYVEAIQ >>XP_011528153 (OMIM: 604960) PREDICTED: protein kinase (488 aa) initn: 2098 init1: 2044 opt: 3256 Z-score: 1748.5 bits: 333.0 E(85289): 1.2e-90 Smith-Waterman score: 3256; 99.6% identity (99.6% similar) in 488 aa overlap (1-486:1-488) 10 20 30 40 50 60 pF1KB8 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 FE--EWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQ :: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEDEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 SSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYP 430 440 450 460 470 480 480 pF1KB8 ANYVEAIQ :::::::: XP_011 ANYVEAIQ >>XP_016884051 (OMIM: 604960) PREDICTED: protein kinase (488 aa) initn: 2098 init1: 2044 opt: 3256 Z-score: 1748.5 bits: 333.0 E(85289): 1.2e-90 Smith-Waterman score: 3256; 99.6% identity (99.6% similar) in 488 aa overlap (1-486:1-488) 10 20 30 40 50 60 pF1KB8 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 FE--EWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQ :: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEDEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 SSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYP 430 440 450 460 470 480 480 pF1KB8 ANYVEAIQ :::::::: XP_016 ANYVEAIQ >>XP_016884052 (OMIM: 604960) PREDICTED: protein kinase (488 aa) initn: 2098 init1: 2044 opt: 3256 Z-score: 1748.5 bits: 333.0 E(85289): 1.2e-90 Smith-Waterman score: 3256; 99.6% identity (99.6% similar) in 488 aa overlap (1-486:1-488) 10 20 30 40 50 60 pF1KB8 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 FE--EWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQ :: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEDEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 SSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYP 430 440 450 460 470 480 480 pF1KB8 ANYVEAIQ :::::::: XP_016 ANYVEAIQ >>XP_011528152 (OMIM: 604960) PREDICTED: protein kinase (488 aa) initn: 2098 init1: 2044 opt: 3256 Z-score: 1748.5 bits: 333.0 E(85289): 1.2e-90 Smith-Waterman score: 3256; 99.6% identity (99.6% similar) in 488 aa overlap (1-486:1-488) 10 20 30 40 50 60 pF1KB8 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 FE--EWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQ :: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEDEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 SSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYP 430 440 450 460 470 480 480 pF1KB8 ANYVEAIQ :::::::: XP_011 ANYVEAIQ >>XP_011528150 (OMIM: 604960) PREDICTED: protein kinase (488 aa) initn: 2098 init1: 2044 opt: 3256 Z-score: 1748.5 bits: 333.0 E(85289): 1.2e-90 Smith-Waterman score: 3256; 99.6% identity (99.6% similar) in 488 aa overlap (1-486:1-488) 10 20 30 40 50 60 pF1KB8 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 FE--EWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQ :: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEDEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 SSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYP 430 440 450 460 470 480 480 pF1KB8 ANYVEAIQ :::::::: XP_011 ANYVEAIQ >>XP_011528148 (OMIM: 604960) PREDICTED: protein kinase (488 aa) initn: 2098 init1: 2044 opt: 3256 Z-score: 1748.5 bits: 333.0 E(85289): 1.2e-90 Smith-Waterman score: 3256; 99.6% identity (99.6% similar) in 488 aa overlap (1-486:1-488) 10 20 30 40 50 60 pF1KB8 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 FE--EWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQ :: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEDEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 SSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYP 430 440 450 460 470 480 480 pF1KB8 ANYVEAIQ :::::::: XP_011 ANYVEAIQ 486 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:48:51 2016 done: Sat Nov 5 21:48:52 2016 Total Scan time: 8.840 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]