FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8653, 234 aa 1>>>pF1KB8653 234 - 234 aa - 234 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2347+/-0.000782; mu= 15.2681+/- 0.047 mean_var=70.9169+/-14.381, 0's: 0 Z-trim(108.6): 20 B-trim: 83 in 1/49 Lambda= 0.152300 statistics sampled from 10296 (10305) to 10296 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.684), E-opt: 0.2 (0.317), width: 16 Scan time: 1.990 The best scores are: opt bits E(32554) CCDS13989.1 SYNGR1 gene_id:9145|Hs108|chr22 ( 233) 1588 357.5 4.2e-99 CCDS13990.1 SYNGR1 gene_id:9145|Hs108|chr22 ( 191) 1121 254.9 2.8e-68 CCDS13991.1 SYNGR1 gene_id:9145|Hs108|chr22 ( 192) 892 204.5 3.9e-53 CCDS10456.1 SYNGR3 gene_id:9143|Hs108|chr16 ( 229) 810 186.6 1.2e-47 CCDS11753.1 SYNGR2 gene_id:9144|Hs108|chr17 ( 224) 733 169.6 1.5e-42 CCDS12717.1 SYNGR4 gene_id:23546|Hs108|chr19 ( 234) 498 118.0 5.3e-27 >>CCDS13989.1 SYNGR1 gene_id:9145|Hs108|chr22 (233 aa) initn: 1586 init1: 1374 opt: 1588 Z-score: 1892.7 bits: 357.5 E(32554): 4.2e-99 Smith-Waterman score: 1588; 99.6% identity (99.6% similar) in 234 aa overlap (1-234:1-233) 10 20 30 40 50 60 pF1KB8 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 YNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 YNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSAL 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 FSQDYMDPSQDSSMPYAPYVEPNTGPDPAGMGGTYQQPANTFDTEPQGYQSQGY :::::::::::::::::::::: ::::::::::::::::::::::::::::::: CCDS13 FSQDYMDPSQDSSMPYAPYVEP-TGPDPAGMGGTYQQPANTFDTEPQGYQSQGY 190 200 210 220 230 >>CCDS13990.1 SYNGR1 gene_id:9145|Hs108|chr22 (191 aa) initn: 1120 init1: 1120 opt: 1121 Z-score: 1339.4 bits: 254.9 E(32554): 2.8e-68 Smith-Waterman score: 1121; 87.2% identity (92.8% similar) in 195 aa overlap (1-195:1-191) 10 20 30 40 50 60 pF1KB8 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 YNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 YNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSAL :::::::::::::::::::::::::::::::::::::::::. :.:: .:.. : . CCDS13 VGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWSLTAALAVRRFK---DLS- 130 140 150 160 170 190 200 210 220 230 pF1KB8 FSQDYMDPSQDSSMPYAPYVEPNTGPDPAGMGGTYQQPANTFDTEPQGYQSQGY :...: :..: CCDS13 FQEEYSTLFPASAQP 180 190 >>CCDS13991.1 SYNGR1 gene_id:9145|Hs108|chr22 (192 aa) initn: 890 init1: 890 opt: 892 Z-score: 1067.4 bits: 204.5 E(32554): 3.9e-53 Smith-Waterman score: 892; 81.4% identity (87.8% similar) in 172 aa overlap (31-195:25-192) 10 20 30 40 50 pF1KB8 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSW-------LFSIVVFGSIVNEGYLNSAS ::: :::::::::::::::::::: CCDS13 MLTLEFGILEFDPSWIGSWTQRSWVSWRSRPGCELFSIVVFGSIVNEGYLNSAS 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 EGEEFCIYNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 EGEEFCIYNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 FWAFLWFVGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQ ::::::::::::::::::::::::::::::::::::::::::::::::. :.:: .:.. CCDS13 FWAFLWFVGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWSLTAALAVRRFK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 IGADSALFSQDYMDPSQDSSMPYAPYVEPNTGPDPAGMGGTYQQPANTFDTEPQGYQSQG : . :...: :..: CCDS13 ---DLS-FQEEYSTLFPASAQP 180 190 >>CCDS10456.1 SYNGR3 gene_id:9143|Hs108|chr16 (229 aa) initn: 812 init1: 597 opt: 810 Z-score: 968.9 bits: 186.6 E(32554): 1.2e-47 Smith-Waterman score: 811; 51.7% identity (76.9% similar) in 238 aa overlap (1-234:1-229) 10 20 30 40 50 60 pF1KB8 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCI :::...:::.::.:.:: ...:.:.:.:::.::.:::.::: ::::::.:. : : :. CCDS10 MEGASFGAGRAGAALDPVSFARRPQTLLRVASWVFSIAVFGPIVNEGYVNTDSGPELRCV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 YNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWF .: : .:: .:::.:. :::.: .: ::: : :::::.::..::: :.: :..:.:::: CCDS10 FNGNAGACRFGVALGLGAFLACAAFLLLDVRFQQISSVRDRRRAVLLDLGFSGLWSFLWF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSAL ::::.:.:::: . : . : ::::::::::::::..:.. .: :.::...:.: .: CCDS10 VGFCFLTNQWQRTAPGPATTQAG-DAARAAIAFSFFSILSWVALTVKALQRFRLGTDMSL 130 140 150 160 170 190 200 210 220 230 pF1KB8 FSQDYMDPSQDSSMPYAPYVEPNTGPDPAGMGGT--YQQP--ANTFDTEPQGYQSQGY :. . . : .:. : : : .:. :: ::.: ..:.:: :.::: .: CCDS10 FATEQL--STGASQAYPGY------PVGSGVEGTETYQSPPFTETLDTSPKGYQVPAY 180 190 200 210 220 >>CCDS11753.1 SYNGR2 gene_id:9144|Hs108|chr17 (224 aa) initn: 763 init1: 543 opt: 733 Z-score: 877.6 bits: 169.6 E(32554): 1.5e-42 Smith-Waterman score: 757; 49.4% identity (75.8% similar) in 231 aa overlap (1-230:1-219) 10 20 30 40 50 60 pF1KB8 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCI ::.:::::.::::.:: .. ::... :.: .:...::. : .::: :. . .:. CCDS11 MESGAYGAAKAGGSFDLRRFLTQPQVVARAVCLVFALIVFSCIYGEGYSNAHESKQMYCV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 YNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWF .::: .:: :: :.::::::. ..:..:.::::::.. ::: :..:. ::.:.:::: CCDS11 FNRNEDACRYGSAIGVLAFLASAFFLVVDAYFPQISNATDRKYLVIGDLLFSALWTFLWF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSAL ::::.:.::: :..::: . :.:..::::.:::::::.:. : ::.:::. :.:. CCDS11 VGFCFLTNQWAVTNPKD--VLVGADSVRAAITFSFFSIFSWGVLASLAYQRYKAGVDD-- 130 140 150 160 170 190 200 210 220 230 pF1KB8 FSQDYMDPSQDSSMPYAPYVEPNTGPDPAGMGGTYQQPANTFDTEP-QGYQSQGY : :.:.::. : . :: : :... : .:::: : ..: .::: CCDS11 FIQNYVDPTPDPNTAYASY--PGASVD------NYQQPPFTQNAETTEGYQPPPVY 180 190 200 210 220 >>CCDS12717.1 SYNGR4 gene_id:23546|Hs108|chr19 (234 aa) initn: 500 init1: 346 opt: 498 Z-score: 598.3 bits: 118.0 E(32554): 5.3e-27 Smith-Waterman score: 498; 37.9% identity (68.2% similar) in 214 aa overlap (20-227:18-227) 10 20 30 40 50 60 pF1KB8 MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCI ..:.:.:: :: .::..::.:....:: :. . :: CCDS12 MHIPKSLQELANSEAVQFLRRPKTITRVFEGVFSLIVFSSLLTDGYQNKMESPQLHCI 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 YNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWF : : :::..:..: ::::.:: .:.::. .:.... . : :. ....:: .:: CCDS12 LNSNSVACSFAVGAGFLAFLSCLAFLVLDTQETRIAGTRFKTAFQLLDFILAVLWAVVWF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 VGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSAL .:::.:::::: : ::. : :...:.:::::.::::..: :: :::: .. :. . CCDS12 MGFCFLANQWQHSPPKEFLL--GSSSAQAAIAFTFFSILVWIFQAYLAFQ--DLRNDAPV 120 130 140 150 160 170 190 200 210 220 230 pF1KB8 FSQDYMDPSQD--SSMPY----APYVEPNTGPDPAGMGGTYQQPANTFDTEPQGYQSQGY . ..: . ...: .: :.:::. ..... .: : :. CCDS12 PYKRFLDEGGMVLTTLPLPSANSPVNMPTTGPNSLSYASSALSPCLTAPKSPRLAMMPDN 180 190 200 210 220 230 234 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 19:54:01 2016 done: Sat Nov 5 19:54:01 2016 Total Scan time: 1.990 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]