Result of FASTA (ccds) for
pF1KB8654
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8654, 862 aa
1>>>pF1KB8654 862 - 862 aa - 862 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6774+/-0.000976; mu= 15.2925+/- 0.059
mean_var=110.0430+/-22.496, 0's: 0 Z-trim(107.8): 8 B-trim: 40 in 1/49
Lambda= 0.122262
statistics sampled from 9813 (9816) to 9813 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.302), width: 16
Scan time: 4.070
The best scores are: opt bits E(32554)
CCDS13797.1 TOP3B gene_id:8940|Hs108|chr22 ( 862) 5964 1063.4 0
CCDS11194.1 TOP3A gene_id:7156|Hs108|chr17 (1001) 1392 257.0 1.2e-67
>>CCDS13797.1 TOP3B gene_id:8940|Hs108|chr22 (862 aa)
initn: 5964 init1: 5964 opt: 5964 Z-score: 5687.1 bits: 1063.4 E(32554): 0
Smith-Waterman score: 5964; 100.0% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KB8 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 LGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 VDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 VDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARR
790 800 810 820 830 840
850 860
pF1KB8 PPGKPNPRRPKDKMSALAAYFV
::::::::::::::::::::::
CCDS13 PPGKPNPRRPKDKMSALAAYFV
850 860
>>CCDS11194.1 TOP3A gene_id:7156|Hs108|chr17 (1001 aa)
initn: 1230 init1: 425 opt: 1392 Z-score: 1327.8 bits: 257.0 E(32554): 1.2e-67
Smith-Waterman score: 1431; 36.0% identity (62.8% similar) in 749 aa overlap (1-742:33-756)
10 20 30
pF1KB8 MKTVLMVAEKPSLAQSIAKILSRGSLSSHK
.. :: :::: . :..:: .:: : . ..
CCDS11 FPVARYALRWLRRPEDRAFSRAAMEMALRGVRKVLCVAEKNDAAKGIADLLSNGRMRRRE
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 GLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMTLDFLGKYNKWDKVDPAELFSQAPTEKK
::. ...:. . :: : . :::: ::... :: .. ::.. .: :: .: ::
CCDS11 GLSKFNKIYEFDYHLYGQNVTMVMTSVSGHLLAHDFQMQFRKWQSCNPLVLF-EAEIEKY
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 EANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGENICFEVLDAVLPVMNKAHGGEKTVFRA
. ... : :. : : :. .:.: :::.::::: ::.. . :: . :.::
CCDS11 CPENFVDIKKTLERETRQCQALVIWTDCDREGENIGFEIIHVC-----KAVKPNLQVLRA
130 140 150 160 170
160 170 180 190 200
pF1KB8 RFSSITDTDICNAMACLGEPDHNEALSVDARQELDLRIGCAFTRFQTKYFQGKYGD-LDS
::: :: . .: : :::. . .::.::::::::: ::::::: .: . . :
CCDS11 RFSEITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAE
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB8 SLISFGPCQTPTLGFCVERHDKIQSFKPETYWVLQAKVNTD-KDRSLLLDWDRVRVFDRE
.:::.: :: ::::: ::: ::.: :: . . ::. : :: . ..: : :.:..
CCDS11 QLISYGSCQFPTLGFVVERFKAIQAFVPEIF--HRIKVTHDHKDGIVEFNWKRHRLFNHT
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB8 IAQMFLNMTKLEKEAQVEATSRKEKAKQRPLALNTVEMLRVASSSLGMGPQHAMQTAERL
.. .. . : : . : :.: :: ::.:::. ..:: .: .. ...:. ::.:
CCDS11 ACLVLYQLCVEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKL
300 310 320 330 340 350
330 340 350 360 370 380
pF1KB8 YTQGYISYPRTETTHYPENFDLKGSLRQQANHPYWADTVKRLLAEGINRPRKGHDAGD-H
:::::::::::::. .:....: ..::. : :. .. .: .: ::.:. . . :
CCDS11 YTQGYISYPRTETNIFPRDLNLTVLVEQQTPDPRWGAFAQSILERGGPTPRNGNKSDQAH
360 370 380 390 400 410
390 400 410 420 430 440
pF1KB8 PPITPMKSATEAELGGDAWRLYEYITRHFIATVSHDCKYLQSTISFRIGPELFTCSGKTV
::: : : .. .: :: ::::.:.:::.: :.: . ..:. . :. : :. : .
CCDS11 PPIHPTKYTN--NLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMI
420 430 440 450 460 470
450 460 470 480 490 500
pF1KB8 LSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGEVKMLEKQTNPPDYLTEAELITLMEKHG
:. .. .:.:.. .. ::. ..:. : . :.:.. .:.:: ::::.::.::::::
CCDS11 LARNYLDVYPYDHWS-DKILPVYEQGSHFQPSTVEMVDGETSPPKLLTEADLIALMEKHG
480 490 500 510 520 530
510 520 530 540 550 560
pF1KB8 IGTDASIPVHINNICQRNYVTVESGRRLKPTNLGIVLVHGYYKIDAELVLPTIRSAVEKQ
:::::. ::..: : :: . .:. : .::. ::.:: .. :. : .:. .: .
CCDS11 IGTDATHAEHIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEAD
540 550 560 570 580 590
570 580 590 600 610 620
pF1KB8 LNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSIAGMDELMEVSFSPLAATGKPLSRCGKC
:.:: .:: : :: . .. .: . :....: .: : ... ..: :..
CCDS11 LKLICDGKKDKFVVLRQQVQKYK---QVFIEAVAKAKKLDE-ALAQYFGNGTELAQQEDI
600 610 620 630 640
630 640 650 660 670 680
pF1KB8 HRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKLYKELRC-PLDDFELVLWSSGS---RGK
. : .: : .: .:.. ..: . . .: : : . . . ..: : ..
CCDS11 YPAMP----EPIR-KCPQCNKDMVLKTKKNGGFY--LSCMGFPECRSAVWLPDSVLEASR
650 660 670 680 690 700
690 700 710 720 730 740
pF1KB8 SYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSMLGIGQCVECESGVLVLDPTSGPK
. .:: : :: .: .: . .. . : . . :: : . .: : ..::
CCDS11 DSSVCPVCQPHPVYR-LK--LKFKRGSLPPTMPLEFVCCIGGCDDTLREILDLRFSGGPP
710 720 730 740 750
750 760 770 780 790 800
pF1KB8 WKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLDVDFNKAKSPLPGDETQHMGCVFC
CCDS11 RASQPSGRLQANQSLNRMDNSQHPQPADSRQTGSSKALAQTLPPPTAAGESNSVTCNCGQ
760 770 780 790 800 810
862 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:12:19 2016 done: Fri Nov 4 14:12:20 2016
Total Scan time: 4.070 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]