Result of FASTA (omim) for
pF1KB8654
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8654, 862 aa
1>>>pF1KB8654 862 - 862 aa - 862 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7203+/-0.000389; mu= 20.4471+/- 0.024
mean_var=105.5797+/-21.575, 0's: 0 Z-trim(114.5): 18 B-trim: 0 in 0/53
Lambda= 0.124820
statistics sampled from 24307 (24323) to 24307 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.285), width: 16
Scan time: 10.510
The best scores are: opt bits E(85289)
NP_001269041 (OMIM: 603582) DNA topoisomerase 3-be ( 862) 5964 1085.5 0
NP_003926 (OMIM: 603582) DNA topoisomerase 3-beta- ( 862) 5964 1085.5 0
NP_001269042 (OMIM: 603582) DNA topoisomerase 3-be ( 862) 5964 1085.5 0
XP_006724413 (OMIM: 603582) PREDICTED: DNA topoiso ( 862) 5964 1085.5 0
XP_005261868 (OMIM: 603582) PREDICTED: DNA topoiso ( 862) 5964 1085.5 0
XP_006724412 (OMIM: 603582) PREDICTED: DNA topoiso ( 862) 5964 1085.5 0
XP_011528784 (OMIM: 603582) PREDICTED: DNA topoiso ( 862) 5964 1085.5 0
XP_005261870 (OMIM: 603582) PREDICTED: DNA topoiso ( 726) 5045 919.9 0
XP_016884528 (OMIM: 603582) PREDICTED: DNA topoiso ( 726) 5045 919.9 0
XP_016884527 (OMIM: 603582) PREDICTED: DNA topoiso ( 727) 4796 875.1 0
XP_016884529 (OMIM: 603582) PREDICTED: DNA topoiso ( 594) 3890 711.8 2.3e-204
XP_016884530 (OMIM: 603582) PREDICTED: DNA topoiso ( 594) 3890 711.8 2.3e-204
NP_004609 (OMIM: 601243) DNA topoisomerase 3-alpha (1001) 1392 262.2 8.5e-69
NP_001307688 (OMIM: 601243) DNA topoisomerase 3-al ( 906) 1221 231.4 1.5e-59
XP_011522303 (OMIM: 601243) PREDICTED: DNA topoiso ( 531) 375 78.8 7.3e-14
>>NP_001269041 (OMIM: 603582) DNA topoisomerase 3-beta-1 (862 aa)
initn: 5964 init1: 5964 opt: 5964 Z-score: 5806.5 bits: 1085.5 E(85289): 0
Smith-Waterman score: 5964; 100.0% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KB8 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 LGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 VDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARR
790 800 810 820 830 840
850 860
pF1KB8 PPGKPNPRRPKDKMSALAAYFV
::::::::::::::::::::::
NP_001 PPGKPNPRRPKDKMSALAAYFV
850 860
>>NP_003926 (OMIM: 603582) DNA topoisomerase 3-beta-1 [H (862 aa)
initn: 5964 init1: 5964 opt: 5964 Z-score: 5806.5 bits: 1085.5 E(85289): 0
Smith-Waterman score: 5964; 100.0% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KB8 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 LGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 VDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARR
790 800 810 820 830 840
850 860
pF1KB8 PPGKPNPRRPKDKMSALAAYFV
::::::::::::::::::::::
NP_003 PPGKPNPRRPKDKMSALAAYFV
850 860
>>NP_001269042 (OMIM: 603582) DNA topoisomerase 3-beta-1 (862 aa)
initn: 5964 init1: 5964 opt: 5964 Z-score: 5806.5 bits: 1085.5 E(85289): 0
Smith-Waterman score: 5964; 100.0% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KB8 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 LGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 VDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARR
790 800 810 820 830 840
850 860
pF1KB8 PPGKPNPRRPKDKMSALAAYFV
::::::::::::::::::::::
NP_001 PPGKPNPRRPKDKMSALAAYFV
850 860
>>XP_006724413 (OMIM: 603582) PREDICTED: DNA topoisomera (862 aa)
initn: 5964 init1: 5964 opt: 5964 Z-score: 5806.5 bits: 1085.5 E(85289): 0
Smith-Waterman score: 5964; 100.0% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KB8 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 LGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 VDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARR
790 800 810 820 830 840
850 860
pF1KB8 PPGKPNPRRPKDKMSALAAYFV
::::::::::::::::::::::
XP_006 PPGKPNPRRPKDKMSALAAYFV
850 860
>>XP_005261868 (OMIM: 603582) PREDICTED: DNA topoisomera (862 aa)
initn: 5964 init1: 5964 opt: 5964 Z-score: 5806.5 bits: 1085.5 E(85289): 0
Smith-Waterman score: 5964; 100.0% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KB8 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 LGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 VDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARR
790 800 810 820 830 840
850 860
pF1KB8 PPGKPNPRRPKDKMSALAAYFV
::::::::::::::::::::::
XP_005 PPGKPNPRRPKDKMSALAAYFV
850 860
>>XP_006724412 (OMIM: 603582) PREDICTED: DNA topoisomera (862 aa)
initn: 5964 init1: 5964 opt: 5964 Z-score: 5806.5 bits: 1085.5 E(85289): 0
Smith-Waterman score: 5964; 100.0% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KB8 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 LGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 VDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARR
790 800 810 820 830 840
850 860
pF1KB8 PPGKPNPRRPKDKMSALAAYFV
::::::::::::::::::::::
XP_006 PPGKPNPRRPKDKMSALAAYFV
850 860
>>XP_011528784 (OMIM: 603582) PREDICTED: DNA topoisomera (862 aa)
initn: 5964 init1: 5964 opt: 5964 Z-score: 5806.5 bits: 1085.5 E(85289): 0
Smith-Waterman score: 5964; 100.0% identity (100.0% similar) in 862 aa overlap (1-862:1-862)
10 20 30 40 50 60
pF1KB8 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 LGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 VDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARR
790 800 810 820 830 840
850 860
pF1KB8 PPGKPNPRRPKDKMSALAAYFV
::::::::::::::::::::::
XP_011 PPGKPNPRRPKDKMSALAAYFV
850 860
>>XP_005261870 (OMIM: 603582) PREDICTED: DNA topoisomera (726 aa)
initn: 5045 init1: 5045 opt: 5045 Z-score: 4913.1 bits: 919.9 E(85289): 0
Smith-Waterman score: 5045; 100.0% identity (100.0% similar) in 726 aa overlap (137-862:1-726)
110 120 130 140 150 160
pF1KB8 RGCDYIVLWLDCDKEGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMAC
::::::::::::::::::::::::::::::
XP_005 MNKAHGGEKTVFRARFSSITDTDICNAMAC
10 20 30
170 180 190 200 210 220
pF1KB8 LGEPDHNEALSVDARQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGEPDHNEALSVDARQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCV
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB8 ERHDKIQSFKPETYWVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERHDKIQSFKPETYWVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVE
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB8 ATSRKEKAKQRPLALNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATSRKEKAKQRPLALNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPE
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB8 NFDLKGSLRQQANHPYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NFDLKGSLRQQANHPYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAW
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB8 RLYEYITRHFIATVSHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLYEYITRHFIATVSHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEES
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB8 LPTCQRGDAFPVGEVKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPTCQRGDAFPVGEVKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNY
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB8 VTVESGRRLKPTNLGIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTVESGRRLKPTNLGIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTL
400 410 420 430 440 450
590 600 610 620 630 640
pF1KB8 DVFKRKFHYFVDSIAGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVFKRKFHYFVDSIAGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHC
460 470 480 490 500 510
650 660 670 680 690 700
pF1KB8 DETYTLPQNGTIKLYKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DETYTLPQNGTIKLYKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGC
520 530 540 550 560 570
710 720 730 740 750 760
pF1KB8 NECTHPSCQHSLSMLGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NECTHPSCQHSLSMLGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRV
580 590 600 610 620 630
770 780 790 800 810 820
pF1KB8 SADTCSVCEAALLDVDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SADTCSVCEAALLDVDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGG
640 650 660 670 680 690
830 840 850 860
pF1KB8 PGRRQGRGRGRARRPPGKPNPRRPKDKMSALAAYFV
::::::::::::::::::::::::::::::::::::
XP_005 PGRRQGRGRGRARRPPGKPNPRRPKDKMSALAAYFV
700 710 720
>>XP_016884528 (OMIM: 603582) PREDICTED: DNA topoisomera (726 aa)
initn: 5045 init1: 5045 opt: 5045 Z-score: 4913.1 bits: 919.9 E(85289): 0
Smith-Waterman score: 5045; 100.0% identity (100.0% similar) in 726 aa overlap (137-862:1-726)
110 120 130 140 150 160
pF1KB8 RGCDYIVLWLDCDKEGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMAC
::::::::::::::::::::::::::::::
XP_016 MNKAHGGEKTVFRARFSSITDTDICNAMAC
10 20 30
170 180 190 200 210 220
pF1KB8 LGEPDHNEALSVDARQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGEPDHNEALSVDARQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCV
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB8 ERHDKIQSFKPETYWVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERHDKIQSFKPETYWVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVE
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB8 ATSRKEKAKQRPLALNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATSRKEKAKQRPLALNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPE
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB8 NFDLKGSLRQQANHPYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFDLKGSLRQQANHPYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAW
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB8 RLYEYITRHFIATVSHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLYEYITRHFIATVSHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEES
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB8 LPTCQRGDAFPVGEVKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPTCQRGDAFPVGEVKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNY
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB8 VTVESGRRLKPTNLGIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTVESGRRLKPTNLGIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTL
400 410 420 430 440 450
590 600 610 620 630 640
pF1KB8 DVFKRKFHYFVDSIAGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVFKRKFHYFVDSIAGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHC
460 470 480 490 500 510
650 660 670 680 690 700
pF1KB8 DETYTLPQNGTIKLYKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DETYTLPQNGTIKLYKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGC
520 530 540 550 560 570
710 720 730 740 750 760
pF1KB8 NECTHPSCQHSLSMLGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NECTHPSCQHSLSMLGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRV
580 590 600 610 620 630
770 780 790 800 810 820
pF1KB8 SADTCSVCEAALLDVDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SADTCSVCEAALLDVDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGG
640 650 660 670 680 690
830 840 850 860
pF1KB8 PGRRQGRGRGRARRPPGKPNPRRPKDKMSALAAYFV
::::::::::::::::::::::::::::::::::::
XP_016 PGRRQGRGRGRARRPPGKPNPRRPKDKMSALAAYFV
700 710 720
>>XP_016884527 (OMIM: 603582) PREDICTED: DNA topoisomera (727 aa)
initn: 4788 init1: 4788 opt: 4796 Z-score: 4670.8 bits: 875.1 E(85289): 0
Smith-Waterman score: 4796; 98.6% identity (98.9% similar) in 715 aa overlap (1-714:1-715)
10 20 30 40 50 60
pF1KB8 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
610 620 630 640 650 660
670 680 690 700 710
pF1KB8 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGM-GCNECTHPSCQHSLS
::::::::::::::::::::::::::::::::::::::::::. : . : :
XP_016 YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKATRGETPVRDPLCVGNSL
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB8 MLGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALL
XP_016 HTPPVPH
862 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:12:20 2016 done: Fri Nov 4 14:12:21 2016
Total Scan time: 10.510 Total Display time: 0.250
Function used was FASTA [36.3.4 Apr, 2011]