FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8655, 566 aa 1>>>pF1KB8655 566 - 566 aa - 566 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1394+/-0.00102; mu= 15.3640+/- 0.062 mean_var=89.2117+/-17.522, 0's: 0 Z-trim(105.7): 7 B-trim: 0 in 0/51 Lambda= 0.135789 statistics sampled from 8549 (8552) to 8549 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.263), width: 16 Scan time: 3.380 The best scores are: opt bits E(32554) CCDS13762.1 CDC45 gene_id:8318|Hs108|chr22 ( 566) 3771 749.2 3.1e-216 CCDS54500.1 CDC45 gene_id:8318|Hs108|chr22 ( 520) 2999 597.9 9.9e-171 CCDS54499.1 CDC45 gene_id:8318|Hs108|chr22 ( 598) 2571 514.1 1.9e-145 >>CCDS13762.1 CDC45 gene_id:8318|Hs108|chr22 (566 aa) initn: 3771 init1: 3771 opt: 3771 Z-score: 3995.5 bits: 749.2 E(32554): 3.1e-216 Smith-Waterman score: 3771; 100.0% identity (100.0% similar) in 566 aa overlap (1-566:1-566) 10 20 30 40 50 60 pF1KB8 MFVSDFRKEFYEVVQSQRVLLFVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MFVSDFRKEFYEVVQSQRVLLFVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELET 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 AFLEHKEQFHYFILINCGANVDLLDILQPDEDTIFFVCDTHRPVNVVNVYNDTQIKLLIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 AFLEHKEQFHYFILINCGANVDLLDILQPDEDTIFFVCDTHRPVNVVNVYNDTQIKLLIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QDDDLEVPAYEDIFRDEEEDEEHSGNDSDGSEPSEKRTRLEEEIVEQTMRRRQRREWEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 QDDDLEVPAYEDIFRDEEEDEEHSGNDSDGSEPSEKRTRLEEEIVEQTMRRRQRREWEAR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 RRDILFDYEQYEYHGTSSAMVMFELAWMLSKDLNDMLWWAIVGLTDQWVQDKITQMKYVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 RRDILFDYEQYEYHGTSSAMVMFELAWMLSKDLNDMLWWAIVGLTDQWVQDKITQMKYVT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 DVGVLQRHVSRHNHRNEDEENTLSVDCTRISFEYDLRLVLYQHWSLHDSLCNTSYTAARF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 DVGVLQRHVSRHNHRNEDEENTLSVDCTRISFEYDLRLVLYQHWSLHDSLCNTSYTAARF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KLWSVHGQKRLQEFLADMGLPLKQVKQKFQAMDISLKENLREMIEESANKFGMKDMRVQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 KLWSVHGQKRLQEFLADMGLPLKQVKQKFQAMDISLKENLREMIEESANKFGMKDMRVQT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 FSIHFGFKHKFLASDVVFATMSLMESPEKDGSGTDHFIQALDSLSRSNLDKLYHGLELAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 FSIHFGFKHKFLASDVVFATMSLMESPEKDGSGTDHFIQALDSLSRSNLDKLYHGLELAK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 KQLRATQQTIASCLCTNLVISQGPFLYCSLMEGTPDVMLFSRPASLSLLSKHLLKSFVCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 KQLRATQQTIASCLCTNLVISQGPFLYCSLMEGTPDVMLFSRPASLSLLSKHLLKSFVCS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 TKNRRCKLLPLVMAAPLSMEHGTVTVVGIPPETDSSDRKNFFGRAFEKAAESTSSRMLHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 TKNRRCKLLPLVMAAPLSMEHGTVTVVGIPPETDSSDRKNFFGRAFEKAAESTSSRMLHN 490 500 510 520 530 540 550 560 pF1KB8 HFDLSVIELKAEDRSKFLDALISLLS :::::::::::::::::::::::::: CCDS13 HFDLSVIELKAEDRSKFLDALISLLS 550 560 >>CCDS54500.1 CDC45 gene_id:8318|Hs108|chr22 (520 aa) initn: 2999 init1: 2999 opt: 2999 Z-score: 3178.7 bits: 597.9 E(32554): 9.9e-171 Smith-Waterman score: 3347; 91.9% identity (91.9% similar) in 566 aa overlap (1-566:1-520) 10 20 30 40 50 60 pF1KB8 MFVSDFRKEFYEVVQSQRVLLFVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MFVSDFRKEFYEVVQSQRVLLFVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELET 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 AFLEHKEQFHYFILINCGANVDLLDILQPDEDTIFFVCDTHRPVNVVNVYNDTQIKLLIK :::::::: :::::: CCDS54 AFLEHKEQ----------------------------------------------IKLLIK 70 130 140 150 160 170 180 pF1KB8 QDDDLEVPAYEDIFRDEEEDEEHSGNDSDGSEPSEKRTRLEEEIVEQTMRRRQRREWEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 QDDDLEVPAYEDIFRDEEEDEEHSGNDSDGSEPSEKRTRLEEEIVEQTMRRRQRREWEAR 80 90 100 110 120 130 190 200 210 220 230 240 pF1KB8 RRDILFDYEQYEYHGTSSAMVMFELAWMLSKDLNDMLWWAIVGLTDQWVQDKITQMKYVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 RRDILFDYEQYEYHGTSSAMVMFELAWMLSKDLNDMLWWAIVGLTDQWVQDKITQMKYVT 140 150 160 170 180 190 250 260 270 280 290 300 pF1KB8 DVGVLQRHVSRHNHRNEDEENTLSVDCTRISFEYDLRLVLYQHWSLHDSLCNTSYTAARF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 DVGVLQRHVSRHNHRNEDEENTLSVDCTRISFEYDLRLVLYQHWSLHDSLCNTSYTAARF 200 210 220 230 240 250 310 320 330 340 350 360 pF1KB8 KLWSVHGQKRLQEFLADMGLPLKQVKQKFQAMDISLKENLREMIEESANKFGMKDMRVQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 KLWSVHGQKRLQEFLADMGLPLKQVKQKFQAMDISLKENLREMIEESANKFGMKDMRVQT 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB8 FSIHFGFKHKFLASDVVFATMSLMESPEKDGSGTDHFIQALDSLSRSNLDKLYHGLELAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 FSIHFGFKHKFLASDVVFATMSLMESPEKDGSGTDHFIQALDSLSRSNLDKLYHGLELAK 320 330 340 350 360 370 430 440 450 460 470 480 pF1KB8 KQLRATQQTIASCLCTNLVISQGPFLYCSLMEGTPDVMLFSRPASLSLLSKHLLKSFVCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 KQLRATQQTIASCLCTNLVISQGPFLYCSLMEGTPDVMLFSRPASLSLLSKHLLKSFVCS 380 390 400 410 420 430 490 500 510 520 530 540 pF1KB8 TKNRRCKLLPLVMAAPLSMEHGTVTVVGIPPETDSSDRKNFFGRAFEKAAESTSSRMLHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 TKNRRCKLLPLVMAAPLSMEHGTVTVVGIPPETDSSDRKNFFGRAFEKAAESTSSRMLHN 440 450 460 470 480 490 550 560 pF1KB8 HFDLSVIELKAEDRSKFLDALISLLS :::::::::::::::::::::::::: CCDS54 HFDLSVIELKAEDRSKFLDALISLLS 500 510 520 >>CCDS54499.1 CDC45 gene_id:8318|Hs108|chr22 (598 aa) initn: 3757 init1: 2555 opt: 2571 Z-score: 2724.6 bits: 514.1 E(32554): 1.9e-145 Smith-Waterman score: 3697; 94.6% identity (94.6% similar) in 598 aa overlap (1-566:1-598) 10 20 30 40 50 60 pF1KB8 MFVSDFRKEFYEVVQSQRVLLFVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MFVSDFRKEFYEVVQSQRVLLFVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELET 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 AFLEHKEQFHYFILINCGANVDLLDILQPDEDTIFFVCDTHRPVNVVNVYNDTQIKLLIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 AFLEHKEQFHYFILINCGANVDLLDILQPDEDTIFFVCDTHRPVNVVNVYNDTQIKLLIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QDDDLEVPAYEDIFRDEEEDEEHSGNDSDGSEPSEKRTRLEEEIVEQTMRRRQRREWEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 QDDDLEVPAYEDIFRDEEEDEEHSGNDSDGSEPSEKRTRLEEEIVEQTMRRRQRREWEAR 130 140 150 160 170 180 190 200 pF1KB8 --------------------------------RRDILFDYEQYEYHGTSSAMVMFELAWM :::::::::::::::::::::::::::: CCDS54 SGSGSEPVAAALEKSSRLFAGPMSDRTAPRSPRRDILFDYEQYEYHGTSSAMVMFELAWM 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB8 LSKDLNDMLWWAIVGLTDQWVQDKITQMKYVTDVGVLQRHVSRHNHRNEDEENTLSVDCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LSKDLNDMLWWAIVGLTDQWVQDKITQMKYVTDVGVLQRHVSRHNHRNEDEENTLSVDCT 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB8 RISFEYDLRLVLYQHWSLHDSLCNTSYTAARFKLWSVHGQKRLQEFLADMGLPLKQVKQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 RISFEYDLRLVLYQHWSLHDSLCNTSYTAARFKLWSVHGQKRLQEFLADMGLPLKQVKQK 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB8 FQAMDISLKENLREMIEESANKFGMKDMRVQTFSIHFGFKHKFLASDVVFATMSLMESPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 FQAMDISLKENLREMIEESANKFGMKDMRVQTFSIHFGFKHKFLASDVVFATMSLMESPE 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB8 KDGSGTDHFIQALDSLSRSNLDKLYHGLELAKKQLRATQQTIASCLCTNLVISQGPFLYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 KDGSGTDHFIQALDSLSRSNLDKLYHGLELAKKQLRATQQTIASCLCTNLVISQGPFLYC 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB8 SLMEGTPDVMLFSRPASLSLLSKHLLKSFVCSTKNRRCKLLPLVMAAPLSMEHGTVTVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 SLMEGTPDVMLFSRPASLSLLSKHLLKSFVCSTKNRRCKLLPLVMAAPLSMEHGTVTVVG 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB8 IPPETDSSDRKNFFGRAFEKAAESTSSRMLHNHFDLSVIELKAEDRSKFLDALISLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 IPPETDSSDRKNFFGRAFEKAAESTSSRMLHNHFDLSVIELKAEDRSKFLDALISLLS 550 560 570 580 590 566 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:56:19 2016 done: Sat Nov 5 21:56:20 2016 Total Scan time: 3.380 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]