FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8657, 454 aa
1>>>pF1KB8657 454 - 454 aa - 454 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5388+/-0.000999; mu= 16.0773+/- 0.060
mean_var=70.8835+/-14.414, 0's: 0 Z-trim(104.5): 47 B-trim: 20 in 1/48
Lambda= 0.152336
statistics sampled from 7888 (7923) to 7888 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.243), width: 16
Scan time: 1.890
The best scores are: opt bits E(32554)
CCDS5339.1 WIPI2 gene_id:26100|Hs108|chr7 ( 454) 2982 664.9 4.7e-191
CCDS34593.1 WIPI2 gene_id:26100|Hs108|chr7 ( 436) 2705 604.0 9.6e-173
CCDS47531.1 WIPI2 gene_id:26100|Hs108|chr7 ( 443) 2661 594.4 7.9e-170
CCDS47532.1 WIPI2 gene_id:26100|Hs108|chr7 ( 425) 2384 533.5 1.6e-151
CCDS47533.1 WIPI2 gene_id:26100|Hs108|chr7 ( 384) 2208 494.8 6.5e-140
CCDS11677.1 WIPI1 gene_id:55062|Hs108|chr17 ( 446) 1574 355.5 6.5e-98
CCDS82193.1 WIPI1 gene_id:55062|Hs108|chr17 ( 364) 1367 309.9 2.7e-84
CCDS11815.2 WDR45B gene_id:56270|Hs108|chr17 ( 344) 388 94.8 1.5e-19
CCDS35250.1 WDR45 gene_id:11152|Hs108|chrX ( 360) 319 79.6 5.8e-15
CCDS14318.1 WDR45 gene_id:11152|Hs108|chrX ( 361) 319 79.6 5.8e-15
>>CCDS5339.1 WIPI2 gene_id:26100|Hs108|chr7 (454 aa)
initn: 2982 init1: 2982 opt: 2982 Z-score: 3543.6 bits: 664.9 E(32554): 4.7e-191
Smith-Waterman score: 2982; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454)
10 20 30 40 50 60
pF1KB8 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
370 380 390 400 410 420
430 440 450
pF1KB8 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
::::::::::::::::::::::::::::::::::
CCDS53 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
430 440 450
>>CCDS34593.1 WIPI2 gene_id:26100|Hs108|chr7 (436 aa)
initn: 2851 init1: 2705 opt: 2705 Z-score: 3214.8 bits: 604.0 E(32554): 9.6e-173
Smith-Waterman score: 2819; 96.0% identity (96.0% similar) in 454 aa overlap (1-454:1-436)
10 20 30 40 50 60
pF1KB8 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
::::::::::::::::::::::::: :::::::::::::::::
CCDS34 MNLASQSGEAGAGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSS
10 20 30 40
70 80 90 100 110 120
pF1KB8 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB8 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB8 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB8 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB8 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB8 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
350 360 370 380 390 400
430 440 450
pF1KB8 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
::::::::::::::::::::::::::::::::::
CCDS34 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
410 420 430
>>CCDS47531.1 WIPI2 gene_id:26100|Hs108|chr7 (443 aa)
initn: 2895 init1: 2661 opt: 2661 Z-score: 3162.5 bits: 594.4 E(32554): 7.9e-170
Smith-Waterman score: 2877; 97.6% identity (97.6% similar) in 454 aa overlap (1-454:1-443)
10 20 30 40 50 60
pF1KB8 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
:::::::::::::::::::::::::::::::::::::::::::::: :::
CCDS47 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK-----------AYT
370 380 390 400
430 440 450
pF1KB8 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
::::::::::::::::::::::::::::::::::
CCDS47 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
410 420 430 440
>>CCDS47532.1 WIPI2 gene_id:26100|Hs108|chr7 (425 aa)
initn: 2764 init1: 2384 opt: 2384 Z-score: 2833.7 bits: 533.5 E(32554): 1.6e-151
Smith-Waterman score: 2714; 93.6% identity (93.6% similar) in 454 aa overlap (1-454:1-425)
10 20 30 40 50 60
pF1KB8 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
::::::::::::::::::::::::: :::::::::::::::::
CCDS47 MNLASQSGEAGAGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSS
10 20 30 40
70 80 90 100 110 120
pF1KB8 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB8 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB8 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB8 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB8 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB8 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
:::::::::::::::::::::::::::::::::::::::::::::: :::
CCDS47 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK-----------AYT
350 360 370 380 390
430 440 450
pF1KB8 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
::::::::::::::::::::::::::::::::::
CCDS47 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
400 410 420
>>CCDS47533.1 WIPI2 gene_id:26100|Hs108|chr7 (384 aa)
initn: 2442 init1: 2208 opt: 2208 Z-score: 2625.3 bits: 494.8 E(32554): 6.5e-140
Smith-Waterman score: 2424; 97.1% identity (97.1% similar) in 383 aa overlap (72-454:13-384)
50 60 70 80 90 100
pF1KB8 VWSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKV
::::::::::::::::::::::::::::::
CCDS47 MFTHVLPFVISADTEDVCIVERLFSSSLVAIVSLKAPRKLKV
10 20 30 40
110 120 130 140 150 160
pF1KB8 CHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 CHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGL
50 60 70 80 90 100
170 180 190 200 210 220
pF1KB8 CALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 CALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATAS
110 120 130 140 150 160
230 240 250 260 270 280
pF1KB8 EKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 EKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVK
170 180 190 200 210 220
290 300 310 320 330 340
pF1KB8 EKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 EKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQK
230 240 250 260 270 280
350 360 370 380 390 400
pF1KB8 IPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 IPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYG
290 300 310 320 330 340
410 420 430 440 450
pF1KB8 AAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
::::: :::::::::::::::::::::::::::::::::::::
CCDS47 AAAGK-----------AYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
350 360 370 380
>>CCDS11677.1 WIPI1 gene_id:55062|Hs108|chr17 (446 aa)
initn: 1540 init1: 1499 opt: 1574 Z-score: 1871.3 bits: 355.5 E(32554): 6.5e-98
Smith-Waterman score: 1574; 58.9% identity (84.9% similar) in 411 aa overlap (44-451:28-434)
20 30 40 50 60 70
pF1KB8 QLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSSVDKLEQIYECTDT
:::.:.:.:::.::::::..:.:.. ..
CCDS11 MEAEAADAPPGGVESALSCFSFNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNEI
10 20 30 40 50
80 90 100 110 120 130
pF1KB8 EDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCL
:: :::::::::::..:: ::...: ::::::::::::::..::...::::::.:::
CCDS11 PDVYIVERLFSSSLVVVVSHTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCL
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB8 EESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLR
:::.:::::.:::.:.:. . : ::.::::::::..: ::::::: : ::. ..: .:.
CCDS11 EESIYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLK
120 130 140 150 160 170
200 210 220 230 240 250
pF1KB8 AANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICS
.. : ::.. :::..:.:::.:::.::::::::::::.:.::::.:::::.:: :.: :
CCDS11 TVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISS
180 190 200 210 220 230
260 270 280 290 300 310
pF1KB8 LAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEM
:.::::..:: :::::::::::::: : .. ::::.::.::.::..::.:.:::.::..:
CCDS11 LVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDM
240 250 260 270 280 290
320 330 340 350 360 370
pF1KB8 FNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQH
..: :::::.:: : :..:::.:.::::.:::::....:.:::::::::.::::.:.: :
CCDS11 MHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTH
300 310 320 330 340 350
380 390 400 410 420 430
pF1KB8 RLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLED
: :: ::.: .. . : . :.:.:.... . . :. : .:..: ::. : . .
CCDS11 SLLGS-GTTEE--NKENDLRPSLPQSYAATVARPS-ASSASTVPGYSEDGGALRGEVIPE
360 370 380 390 400 410
440 450
pF1KB8 EASA---LRLDEDSEHPPMILRTD
. : . ::...: ::.::
CCDS11 HEFATGPVCLDDENEFPPIILCRGNQKGKTKQS
420 430 440
>>CCDS82193.1 WIPI1 gene_id:55062|Hs108|chr17 (364 aa)
initn: 1333 init1: 1292 opt: 1367 Z-score: 1626.8 bits: 309.9 E(32554): 2.7e-84
Smith-Waterman score: 1367; 58.7% identity (84.8% similar) in 356 aa overlap (99-451:1-352)
70 80 90 100 110 120
pF1KB8 ECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQR
..: ::::::::::::::..::...:::::
CCDS82 MNVYHFKKGTEICNYSYSSNILSIRLNRQR
10 20 30
130 140 150 160 170 180
pF1KB8 LIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFD
:.::::::.:::::.:::.:.:. . : ::.::::::::..: ::::::: : ::. ..:
CCDS82 LLVCLEESIYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYD
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB8 TINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRC
.:... : ::.. :::..:.:::.:::.::::::::::::.:.::::.:::::.::
CCDS82 GNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRY
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB8 VSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPS
:.: ::.::::..:: :::::::::::::: : .. ::::.::.::.::..::.:.:::.
CCDS82 VTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPT
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB8 QVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECA
::..:..: :::::.:: : :..:::.:.::::.:::::....:.:::::::::.::::.
CCDS82 QVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECV
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB8 LMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGG
:.: : : :: ::.: .. . : . :.:.:.... . . :. : .:..: ::. :
CCDS82 LIKTHSLLGS-GTTEE--NKENDLRPSLPQSYAATVARPS-ASSASTVPGYSEDGGALRG
280 290 300 310 320
430 440 450
pF1KB8 ACLEDEASA---LRLDEDSEHPPMILRTD
. .. : . ::...: ::.::
CCDS82 EVIPEHEFATGPVCLDDENEFPPIILCRGNQKGKTKQS
330 340 350 360
>>CCDS11815.2 WDR45B gene_id:56270|Hs108|chr17 (344 aa)
initn: 343 init1: 276 opt: 388 Z-score: 464.3 bits: 94.8 E(32554): 1.5e-19
Smith-Waterman score: 443; 31.0% identity (56.8% similar) in 368 aa overlap (11-367:10-328)
10 20 30 40 50 60
pF1KB8 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
: : ::.:.::::. : .: : ..:.. .. .
CCDS11 MNLLPCNPHGNG-LLYAGFNQDH----GC--------------FACGMENGFRVYNTDP
10 20 30 40
70 80 90 100 110
pF1KB8 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSL-KAPR----KLKVCHFKKGTEICNYSY
. . :. : . : :: :: . .:.:. : :. :. . : . . .
CCDS11 LKEKEK-QEFLEG-GVGHVEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEF
50 60 70 80 90
120 130 140 150 160 170
pF1KB8 SNTILAVKLNRQRLIVCLEESL----YIHNIRDMKVLHTIRETPPNPAGLCALSINNDNC
:. . :::: :.:..: :. . . :: ....:. :: :: :::.: :..:
CCDS11 STEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLHVF----ETCYNPKGLCVLCPNSNNS
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB8 YLAYPGSATIGEVQVFDTINLRAANM-IPAHDSPLAALAFDASGTKLATASEKGTVIRVF
::.::. : :.::. : . . . ::::.. :. .:.. .::..::::::::.::.:
CCDS11 LLAFPGTHT-GHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIF
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB8 SIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTT
. :. . :.::: . : . :..:. .. .::. ::::: : :..
CCDS11 DTSSGHLIQELRRGSQAANIYC-INFNQDASLICVSSDHGTVHIFAAEDPKRNKQSS---
220 230 240 250 260
300 310 320 330 340
pF1KB8 WTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGA-
.::.:.:: ..:.. .:. ..: : ::...: : ...
CCDS11 ---------LASASFLP----KYFSSKWSFSKFQVP-SGSPCICAFGT---EPNAVIAIC
270 280 290 300 310
350 360 370 380 390 400
pF1KB8 ADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTY
::: : . ..:. :::
CCDS11 ADGSYYKFLFNPK--GECIRDVYAQFLEMTDDKL
320 330 340
>>CCDS35250.1 WDR45 gene_id:11152|Hs108|chrX (360 aa)
initn: 260 init1: 138 opt: 319 Z-score: 382.1 bits: 79.6 E(32554): 5.8e-15
Smith-Waterman score: 335; 26.6% identity (57.1% similar) in 308 aa overlap (78-367:53-343)
50 60 70 80 90 100
pF1KB8 GSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSL-KAPRKLKVCHF--
.:: : :.:.:.:. ..:. .. .
CCDS35 CAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRSNLLALVGGGSSPKFSEISVLIW
30 40 50 60 70 80
110 120 130 140 150
pF1KB8 ---KKGTE-----ICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPP
..: . . ...... .:.:.. ...... :.. .:.... : .:
CCDS35 DDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDNPRKLFEFDTRD
90 100 110 120 130 140
160 170 180 190 200 210
pF1KB8 NPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLR-----AANMIPAHDSPLAALAFD
:: ::: : . .. :..:: : .:. : . . : : ::.: .: ....
CCDS35 NPKGLCDLCPSLEKQLLVFPGHKC-GSLQLVDLASTKPGTSSAPFTINAHQSDIACVSLN
150 160 170 180 190 200
220 230 240 250 260 270
pF1KB8 ASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTET
:: .:.::.:::.::.:. .:: :.:::. . : . :: :. :: :::. :
CCDS35 QPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYC-INFSHDSSFLCASSDKGT
210 220 230 240 250 260
280 290 300 310 320 330
pF1KB8 VHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHK
:::: :. .. . . . ::: .:. :: . .:. .:
CCDS35 VHIFALKDTR----LNRRSALARVGKVGPMIGQYVDSQWS--------LASFTVP-AESA
270 280 290 300
340 350 360 370 380
pF1KB8 NICSLA--TIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSA
::... : ... ... .:: .. : . :. :.:
CCDS35 CICAFGRNTSKNVNSVIAICVDGTFHKYVFTPD--GNCNREAFDVYLDICDDDDF
310 320 330 340 350 360
390 400 410 420 430 440
pF1KB8 SHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPM
>>CCDS14318.1 WDR45 gene_id:11152|Hs108|chrX (361 aa)
initn: 260 init1: 138 opt: 319 Z-score: 382.1 bits: 79.6 E(32554): 5.8e-15
Smith-Waterman score: 333; 26.5% identity (56.6% similar) in 309 aa overlap (78-367:53-344)
50 60 70 80 90 100
pF1KB8 GSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSL-KAPRKLKVCHF--
.:: : :.:.:.:. ..:. ..
CCDS14 CAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRSNLLALVGGGSSPKFSEISAVLI
30 40 50 60 70 80
110 120 130 140 150
pF1KB8 ----KKGTE-----ICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETP
..: . . ...... .:.:.. ...... :.. .:.... : .:
CCDS14 WDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDNPRKLFEFDTR
90 100 110 120 130 140
160 170 180 190 200 210
pF1KB8 PNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLR-----AANMIPAHDSPLAALAF
:: ::: : . .. :..:: : .:. : . . : : ::.: .: ...
CCDS14 DNPKGLCDLCPSLEKQLLVFPGHKC-GSLQLVDLASTKPGTSSAPFTINAHQSDIACVSL
150 160 170 180 190 200
220 230 240 250 260 270
pF1KB8 DASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTE
. :: .:.::.:::.::.:. .:: :.:::. . : . :: :. :: :::.
CCDS14 NQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYC-INFSHDSSFLCASSDKG
210 220 230 240 250 260
280 290 300 310 320 330
pF1KB8 TVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGH
::::: :. .. . . . ::: .:. :: . .:. .:
CCDS14 TVHIFALKDTR----LNRRSALARVGKVGPMIGQYVDSQWS--------LASFTVP-AES
270 280 290 300
340 350 360 370 380
pF1KB8 KNICSLA--TIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDS
::... : ... ... .:: .. : . :. :.:
CCDS14 ACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPD--GNCNREAFDVYLDICDDDDF
310 320 330 340 350 360
390 400 410 420 430 440
pF1KB8 ASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASALRLDEDSEHPP
454 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:14:15 2016 done: Fri Nov 4 14:14:15 2016
Total Scan time: 1.890 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]