FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8658, 520 aa 1>>>pF1KB8658 520 - 520 aa - 520 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.8208+/-0.00115; mu= -6.8819+/- 0.071 mean_var=524.7184+/-108.061, 0's: 0 Z-trim(116.7): 33 B-trim: 184 in 1/52 Lambda= 0.055990 statistics sampled from 17281 (17305) to 17281 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.803), E-opt: 0.2 (0.532), width: 16 Scan time: 3.370 The best scores are: opt bits E(32554) CCDS47056.1 FIP1L1 gene_id:81608|Hs108|chr4 ( 520) 3565 302.3 8.5e-82 CCDS3491.1 FIP1L1 gene_id:81608|Hs108|chr4 ( 594) 2022 177.8 3.1e-44 CCDS47055.1 FIP1L1 gene_id:81608|Hs108|chr4 ( 588) 1548 139.5 1e-32 >>CCDS47056.1 FIP1L1 gene_id:81608|Hs108|chr4 (520 aa) initn: 3565 init1: 3565 opt: 3565 Z-score: 1582.0 bits: 302.3 E(32554): 8.5e-82 Smith-Waterman score: 3565; 100.0% identity (100.0% similar) in 520 aa overlap (1-520:1-520) 10 20 30 40 50 60 pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 RMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSRRLPGAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 RMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSRRLPGAI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 DVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 DVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 PGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 PSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHES 430 440 450 460 470 480 490 500 510 520 pF1KB8 EEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE :::::::::::::::::::::::::::::::::::::::: CCDS47 EEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 490 500 510 520 >>CCDS3491.1 FIP1L1 gene_id:81608|Hs108|chr4 (594 aa) initn: 3140 init1: 2014 opt: 2022 Z-score: 907.7 bits: 177.8 E(32554): 3.1e-44 Smith-Waterman score: 3242; 89.3% identity (89.3% similar) in 551 aa overlap (29-520:44-594) 10 20 30 40 50 pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGV :::::::::::::::::::::::::::::: CCDS34 SGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANPPSGIEDETAENGV 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB8 PKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 PKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTG 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB8 TKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 TKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQK 140 150 160 170 180 190 180 190 200 210 pF1KB8 RIRMGLEVIPVTSTTNKIT-----------------------VQQGRTGNSEKETALPST ::::::::::::::::::: :::::::::::::::::: CCDS34 RIRMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGRTGNSEKETALPST 200 210 220 230 240 250 220 230 pF1KB8 KAEFTSPPSLFKTGLPPSR------------------------------------RLPGA ::::::::::::::::::: ::::: CCDS34 KAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYGRAESPDLRRLPGA 260 270 280 290 300 310 240 250 260 270 280 290 pF1KB8 IDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 IDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPP 320 330 340 350 360 370 300 310 320 330 340 350 pF1KB8 FLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 FLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPH 380 390 400 410 420 430 360 370 380 390 400 410 pF1KB8 LPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 LPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSP 440 450 460 470 480 490 420 430 440 450 460 470 pF1KB8 TPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 TPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHE 500 510 520 530 540 550 480 490 500 510 520 pF1KB8 SEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE ::::::::::::::::::::::::::::::::::::::::: CCDS34 SEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 560 570 580 590 >>CCDS47055.1 FIP1L1 gene_id:81608|Hs108|chr4 (588 aa) initn: 2793 init1: 1482 opt: 1548 Z-score: 700.8 bits: 139.5 E(32554): 1e-32 Smith-Waterman score: 3159; 87.7% identity (87.7% similar) in 552 aa overlap (37-520:37-588) 10 20 30 40 50 60 pF1KB8 ERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPKPKVTET :::::::::::::::::::::::::::::: CCDS47 ERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPKPKVTET 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTKVKGVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 EDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTKVKGVDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRIRMGLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 DAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRIRMGLEV 130 140 150 160 170 180 190 200 210 220 pF1KB8 IPVTSTTNKIT-----------------------VQQGRTGNSEKETALPSTKAEFTSPP ::::::::::: :::::::::::::::::::::::::: CCDS47 IPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGRTGNSEKETALPSTKAEFTSPP 190 200 210 220 230 240 230 240 pF1KB8 SLFKTGLPPSR------------------------------------RLPGAIDVIGQTI ::::::::::: ::::::::::::: CCDS47 SLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYGRAESPDLRRLPGAIDVIGQTI 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB8 TISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 TISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTV 310 320 330 340 350 360 310 320 330 340 350 pF1KB8 STAPPLIPPPG---------FPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFP ::::::::::: :::::::::::::::::::::::::::::::::::::::: CCDS47 STAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFP 370 380 390 400 410 420 360 370 380 390 400 410 pF1KB8 HLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 HLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHS 430 440 450 460 470 480 420 430 440 450 460 470 pF1KB8 PTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRH 490 500 510 520 530 540 480 490 500 510 520 pF1KB8 ESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE :::::::::::::::::::::::::::::::::::::::::: CCDS47 ESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 550 560 570 580 520 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:15:08 2016 done: Fri Nov 4 14:15:08 2016 Total Scan time: 3.370 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]