FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8658, 520 aa 1>>>pF1KB8658 520 - 520 aa - 520 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.7681+/-0.000452; mu= -12.6302+/- 0.029 mean_var=572.8652+/-118.155, 0's: 0 Z-trim(124.8): 74 B-trim: 895 in 1/60 Lambda= 0.053586 statistics sampled from 47140 (47221) to 47140 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.813), E-opt: 0.2 (0.554), width: 16 Scan time: 11.180 The best scores are: opt bits E(85289) NP_001128410 (OMIM: 607686) pre-mRNA 3'-end-proces ( 520) 3565 290.1 1.1e-77 XP_005265839 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 535) 3380 275.8 2.2e-73 XP_016864158 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 529) 2496 207.5 8.1e-53 XP_005265838 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 544) 2311 193.2 1.7e-48 XP_016864154 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 558) 2292 191.8 4.7e-48 XP_016864157 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 543) 2290 191.6 5.1e-48 XP_016864160 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 499) 2044 172.5 2.6e-42 XP_016864151 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 579) 2022 170.9 9.2e-42 NP_112179 (OMIM: 607686) pre-mRNA 3'-end-processin ( 594) 2022 170.9 9.4e-42 XP_016864155 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 556) 2016 170.4 1.2e-41 XP_005265831 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 571) 2016 170.4 1.3e-41 XP_016864153 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 565) 1644 141.7 5.7e-33 XP_016864156 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 552) 1548 134.2 9.6e-31 XP_016864152 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 567) 1548 134.2 9.7e-31 XP_005265830 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 580) 1548 134.3 9.9e-31 NP_001128409 (OMIM: 607686) pre-mRNA 3'-end-proces ( 588) 1548 134.3 1e-30 XP_005265826 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 603) 1548 134.3 1e-30 XP_016864159 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 526) 1407 123.3 1.8e-27 XP_005265836 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 549) 1140 102.7 3e-21 XP_005265835 (OMIM: 607686) PREDICTED: pre-mRNA 3' ( 558) 1140 102.7 3e-21 >>NP_001128410 (OMIM: 607686) pre-mRNA 3'-end-processing (520 aa) initn: 3565 init1: 3565 opt: 3565 Z-score: 1516.0 bits: 290.1 E(85289): 1.1e-77 Smith-Waterman score: 3565; 100.0% identity (100.0% similar) in 520 aa overlap (1-520:1-520) 10 20 30 40 50 60 pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 RMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSRRLPGAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSRRLPGAI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 DVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 PGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 PSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHES 430 440 450 460 470 480 490 500 510 520 pF1KB8 EEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE :::::::::::::::::::::::::::::::::::::::: NP_001 EEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 490 500 510 520 >>XP_005265839 (OMIM: 607686) PREDICTED: pre-mRNA 3'-end (535 aa) initn: 3380 init1: 3380 opt: 3380 Z-score: 1438.6 bits: 275.8 E(85289): 2.2e-73 Smith-Waterman score: 3525; 97.2% identity (97.2% similar) in 535 aa overlap (1-520:1-535) 10 20 30 40 pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYG---------------DENEVERPEEENASANP :::::::::::::::::::::::::::: ::::::::::::::::: XP_005 MSAGEVERLVSELSGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 FKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPF 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB8 FPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSR 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB8 SARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRER 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB8 ERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEET 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB8 RHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 490 500 510 520 530 >>XP_016864158 (OMIM: 607686) PREDICTED: pre-mRNA 3'-end (529 aa) initn: 3246 init1: 2168 opt: 2496 Z-score: 1069.3 bits: 207.5 E(85289): 8.1e-53 Smith-Waterman score: 3537; 98.3% identity (98.3% similar) in 529 aa overlap (1-520:1-529) 10 20 30 40 50 60 pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 RMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSRRLPGAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSRRLPGAI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 DVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPF 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 LPPPPTVSTAPPLIPPPG---------FPPPPGAPPPSLIPTIESGHSSGYDSRSARAFP :::::::::::::::::: ::::::::::::::::::::::::::::::::: XP_016 LPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFP 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 YGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRER 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 ERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSR 430 440 450 460 470 480 480 490 500 510 520 pF1KB8 SNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 490 500 510 520 >>XP_005265838 (OMIM: 607686) PREDICTED: pre-mRNA 3'-end (544 aa) initn: 3061 init1: 1983 opt: 2311 Z-score: 991.8 bits: 193.2 E(85289): 1.7e-48 Smith-Waterman score: 3497; 95.6% identity (95.6% similar) in 544 aa overlap (1-520:1-544) 10 20 30 40 pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYG---------------DENEVERPEEENASANP :::::::::::::::::::::::::::: ::::::::::::::::: XP_005 MSAGEVERLVSELSGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 FKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPF 250 260 270 280 290 300 290 300 310 320 330 pF1KB8 FPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPG---------FPPPPGAPPPSLIPTIES ::::::::::::::::::::::::::::::::: :::::::::::::::::: XP_005 FPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPTIES 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB8 GHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRE 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB8 RDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRE 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB8 RRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEA 490 500 510 520 530 540 520 pF1KB8 TPAE :::: XP_005 TPAE >>XP_016864154 (OMIM: 607686) PREDICTED: pre-mRNA 3'-end (558 aa) initn: 2417 init1: 2245 opt: 2292 Z-score: 983.8 bits: 191.8 E(85289): 4.7e-48 Smith-Waterman score: 3433; 93.1% identity (93.1% similar) in 552 aa overlap (7-520:7-558) 10 20 30 40 pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYG---------------DENEVERPEEENASANP :::::::::::::::::::::: ::::::::::::::::: XP_016 MSAGEVERLVSELSGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF 130 140 150 160 170 180 170 180 190 200 pF1KB8 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKIT-----------------------VQQGR :::::::::::::::::::::::::::::::: ::::: XP_016 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGR 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB8 TGNSEKETALPSTKAEFTSPPSLFKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGNSEKETALPSTKAEFTSPPSLFKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENS 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB8 NIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPP 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB8 PGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYAR 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB8 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB8 RHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 490 500 510 520 530 540 510 520 pF1KB8 AGSEPAPEQESTEATPAE :::::::::::::::::: XP_016 AGSEPAPEQESTEATPAE 550 >>XP_016864157 (OMIM: 607686) PREDICTED: pre-mRNA 3'-end (543 aa) initn: 2245 init1: 2245 opt: 2290 Z-score: 983.1 bits: 191.6 E(85289): 5.1e-48 Smith-Waterman score: 3509; 95.8% identity (95.8% similar) in 543 aa overlap (1-520:1-543) 10 20 30 40 50 60 pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI 130 140 150 160 170 180 190 200 210 pF1KB8 RMGLEVIPVTSTTNKIT-----------------------VQQGRTGNSEKETALPSTKA ::::::::::::::::: :::::::::::::::::::: XP_016 RMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGRTGNSEKETALPSTKA 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB8 EFTSPPSLFKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFTSPPSLFKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDN 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB8 NFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESG 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB8 HSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRER 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB8 DRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB8 RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEAT 490 500 510 520 530 540 520 pF1KB8 PAE ::: XP_016 PAE >>XP_016864160 (OMIM: 607686) PREDICTED: pre-mRNA 3'-end (499 aa) initn: 2352 init1: 1983 opt: 2044 Z-score: 880.7 bits: 172.5 E(85289): 2.6e-42 Smith-Waterman score: 2362; 85.1% identity (89.6% similar) in 424 aa overlap (1-400:1-419) 10 20 30 40 pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYG---------------DENEVERPEEENASANP :::::::::::::::::::::::::::: ::::::::::::::::: XP_016 MSAGEVERLVSELSGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 FKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKTGLPPSRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPF 250 260 270 280 290 300 290 300 310 320 330 pF1KB8 FPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPG---------FPPPPGAPPPSLIPTIES ::::::::::::::::::::::::::::::::: :::::::::::::::::: XP_016 FPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPTIES 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB8 GHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRE :::::::::::::::::: :. . .. ......: . ....: ... : :. XP_016 GHSSGYDSRSARAFPYGN-AMKNDTDTGNMQKEVMSVTEQVE---KKKNDIEKD-DTGRK 370 380 390 400 410 400 410 420 430 440 450 pF1KB8 RDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRE : : XP_016 RKPDISLLEVIVDVAMKVKKEIVTGDTNTKNLKEAKKEKKRAVSLPLNRRAPKLHLQNRH 420 430 440 450 460 470 >>XP_016864151 (OMIM: 607686) PREDICTED: pre-mRNA 3'-end (579 aa) initn: 3325 init1: 2014 opt: 2022 Z-score: 870.8 bits: 170.9 E(85289): 9.2e-42 Smith-Waterman score: 3250; 89.3% identity (89.3% similar) in 552 aa overlap (28-520:28-579) 10 20 30 40 50 60 pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK ::::::::::::::::::::::::::::::::: XP_016 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI 130 140 150 160 170 180 190 200 210 pF1KB8 RMGLEVIPVTSTTNKIT-----------------------VQQGRTGNSEKETALPSTKA ::::::::::::::::: :::::::::::::::::::: XP_016 RMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGRTGNSEKETALPSTKA 190 200 210 220 230 240 220 230 240 pF1KB8 EFTSPPSLFKTGLPPSR------------------------------------RLPGAID ::::::::::::::::: ::::::: XP_016 EFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYGRAESPDLRRLPGAID 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB8 VIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFL 310 320 330 340 350 360 310 320 330 340 350 360 pF1KB8 PPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLP 370 380 390 400 410 420 370 380 390 400 410 420 pF1KB8 GSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTP 430 440 450 460 470 480 430 440 450 460 470 480 pF1KB8 SVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESE 490 500 510 520 530 540 490 500 510 520 pF1KB8 EGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE ::::::::::::::::::::::::::::::::::::::: XP_016 EGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 550 560 570 >>NP_112179 (OMIM: 607686) pre-mRNA 3'-end-processing fa (594 aa) initn: 3140 init1: 2014 opt: 2022 Z-score: 870.6 bits: 170.9 E(85289): 9.4e-42 Smith-Waterman score: 3242; 89.3% identity (89.3% similar) in 551 aa overlap (29-520:44-594) 10 20 30 40 50 pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGV :::::::::::::::::::::::::::::: NP_112 SGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANPPSGIEDETAENGV 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB8 PKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 PKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTG 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB8 TKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 TKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQK 140 150 160 170 180 190 180 190 200 210 pF1KB8 RIRMGLEVIPVTSTTNKIT-----------------------VQQGRTGNSEKETALPST ::::::::::::::::::: :::::::::::::::::: NP_112 RIRMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGRTGNSEKETALPST 200 210 220 230 240 250 220 230 pF1KB8 KAEFTSPPSLFKTGLPPSR------------------------------------RLPGA ::::::::::::::::::: ::::: NP_112 KAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYGRAESPDLRRLPGA 260 270 280 290 300 310 240 250 260 270 280 290 pF1KB8 IDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 IDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPP 320 330 340 350 360 370 300 310 320 330 340 350 pF1KB8 FLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 FLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPH 380 390 400 410 420 430 360 370 380 390 400 410 pF1KB8 LPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 LPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSP 440 450 460 470 480 490 420 430 440 450 460 470 pF1KB8 TPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 TPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHE 500 510 520 530 540 550 480 490 500 510 520 pF1KB8 SEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE ::::::::::::::::::::::::::::::::::::::::: NP_112 SEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 560 570 580 590 >>XP_016864155 (OMIM: 607686) PREDICTED: pre-mRNA 3'-end (556 aa) initn: 2343 init1: 2014 opt: 2016 Z-score: 868.5 bits: 170.4 E(85289): 1.2e-41 Smith-Waterman score: 3458; 93.5% identity (93.5% similar) in 552 aa overlap (5-520:5-556) 10 20 30 40 50 60 pF1KB8 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 RMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSR------ :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RMGLEVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSRNSTSSQ 190 200 210 220 230 240 240 250 260 pF1KB8 ------------------------------RLPGAIDVIGQTITISRVEGRRRANENSNI :::::::::::::::::::::::::::::: XP_016 SQTSTASRKANSSVGKWQDRYGRAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNI 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB8 QVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPG 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB8 APPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARRE 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB8 KDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERH 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB8 RASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAG 490 500 510 520 530 540 510 520 pF1KB8 SEPAPEQESTEATPAE :::::::::::::::: XP_016 SEPAPEQESTEATPAE 550 520 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:15:09 2016 done: Fri Nov 4 14:15:10 2016 Total Scan time: 11.180 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]