Result of FASTA (omim) for pF1KB8659
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8659, 658 aa
  1>>>pF1KB8659 658 - 658 aa - 658 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.8444+/-0.000378; mu= 7.7564+/- 0.023
 mean_var=148.1067+/-30.209, 0's: 0 Z-trim(117.7): 17  B-trim: 789 in 2/51
 Lambda= 0.105387
 statistics sampled from 29947 (29961) to 29947 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.351), width:  16
 Scan time: 11.590

The best scores are:                                      opt bits E(85289)
NP_060855 (OMIM: 610780) large subunit GTPase 1 ho ( 658) 4464 690.9  4e-198
XP_016862285 (OMIM: 610780) PREDICTED: large subun ( 500) 3289 512.1 1.9e-144
NP_005266 (OMIM: 143024) guanine nucleotide-bindin ( 607)  426 76.9 2.4e-13
XP_005249072 (OMIM: 143024) PREDICTED: guanine nuc ( 607)  426 76.9 2.4e-13
NP_001310553 (OMIM: 609365) nucleolar GTP-binding  ( 548)  246 49.5 3.9e-05
NP_037417 (OMIM: 609365) nucleolar GTP-binding pro ( 731)  246 49.6 4.9e-05
NP_001310552 (OMIM: 609365) nucleolar GTP-binding  ( 799)  230 47.2 0.00028
NP_001171748 (OMIM: 300873) guanine nucleotide-bin ( 582)  194 41.6  0.0097
NP_061940 (OMIM: 300873) guanine nucleotide-bindin ( 582)  194 41.6  0.0097


>>NP_060855 (OMIM: 610780) large subunit GTPase 1 homolo  (658 aa)
 initn: 4464 init1: 4464 opt: 4464  Z-score: 3678.0  bits: 690.9 E(85289): 4e-198
Smith-Waterman score: 4464; 99.8% identity (100.0% similar) in 658 aa overlap (1-658:1-658)

               10        20        30        40        50        60
pF1KB8 MGRRRAPAGGSLGRALMRHQTQRSRSHRHTDSWLHTSELNDGYDWGRLNLQSVTEQSSLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MGRRRAPAGGSLGRALMRHQTQRSRSHRHTDSWLHTSELNDGYDWGRLNLQSVTEQSSLD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 DFLATAELAGTEFVAEKLNIKFVPAEARTGLLSFEESQRIKKLHEENKQFLCIPRRPNWN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DFLATAELAGTEFVAEKLNIKFVPAEARTGLLSFEESQRIKKLHEENKQFLCIPRRPNWN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 QNTTPEELKQAEKDNFLEWRRQLVRLEEEQKLILTPFERNLDFWRQLWRVIERSDIVVQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QNTTPEELKQAEKDNFLEWRRQLVRLEEEQKLILTPFERNLDFWRQLWRVIERSDIVVQI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 VDARNPLLFRCEDLECYVKEMDANKENVILINKADLLTAEQRSAWAMYFEKEDVKVIFWS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VDARNPLLFRCEDLECYVKEMDANKENVILINKADLLTAEQRSAWAMYFEKEDVKVIFWS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 ALAGAIPLNGDSEEEANRDDRQSNTTEFGHSSFDQAEISHSESEHLPARDSPSLSENPTT
       ::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
NP_060 ALAGAIPLNGDSEEEANRDDRQSNTTKFGHSSFDQAEISHSESEHLPARDSPSLSENPTT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 DEDDSEYEDCPEEEEDDWQTCSEEDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DEDDSEYEDCPEEEEDDWQTCSEEDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNF
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 SHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGH
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 TKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 HVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKDYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 HVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKDYV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 SGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQE
              550       560       570       580       590       600

              610       620       630       640       650        
pF1KB8 NVRALTKGVQAVMGYKPGSGVVTASTASSENGAGKPWKKHGNRNKKEKSRRLYKHLDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 NVRALTKGVQAVMGYKPGSGVVTASTASSENGAGKPWKKHGNRNKKEKSRRLYKHLDM
              610       620       630       640       650        

>>XP_016862285 (OMIM: 610780) PREDICTED: large subunit G  (500 aa)
 initn: 3289 init1: 3289 opt: 3289  Z-score: 2714.3  bits: 512.1 E(85289): 1.9e-144
Smith-Waterman score: 3289; 99.6% identity (100.0% similar) in 485 aa overlap (174-658:16-500)

           150       160       170       180       190       200   
pF1KB8 VRLEEEQKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEMDA
                                     .:::::::::::::::::::::::::::::
XP_016                MEEVGLAIPASAGQPNDIVVQIVDARNPLLFRCEDLECYVKEMDA
                              10        20        30        40     

           210       220       230       240       250       260   
pF1KB8 NKENVILINKADLLTAEQRSAWAMYFEKEDVKVIFWSALAGAIPLNGDSEEEANRDDRQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKENVILINKADLLTAEQRSAWAMYFEKEDVKVIFWSALAGAIPLNGDSEEEANRDDRQS
          50        60        70        80        90       100     

           270       280       290       300       310       320   
pF1KB8 NTTEFGHSSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPEEEEDDWQTCSE
       :::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTTKFGHSSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPEEEEDDWQTCSE
         110       120       130       140       150       160     

           330       340       350       360       370       380   
pF1KB8 EDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVK
         170       180       190       200       210       220     

           390       400       410       420       430       440   
pF1KB8 DGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVM
         230       240       250       260       270       280     

           450       460       470       480       490       500   
pF1KB8 PSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRP
         290       300       310       320       330       340     

           510       520       530       540       550       560   
pF1KB8 PTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKDYVSGKLLYCHPPPGRDPVTFQHQHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKDYVSGKLLYCHPPPGRDPVTFQHQHQ
         350       360       370       380       390       400     

           570       580       590       600       610       620   
pF1KB8 RLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVMGYKPGSGVVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVMGYKPGSGVVT
         410       420       430       440       450       460     

           630       640       650        
pF1KB8 ASTASSENGAGKPWKKHGNRNKKEKSRRLYKHLDM
       :::::::::::::::::::::::::::::::::::
XP_016 ASTASSENGAGKPWKKHGNRNKKEKSRRLYKHLDM
         470       480       490       500

>>NP_005266 (OMIM: 143024) guanine nucleotide-binding pr  (607 aa)
 initn: 560 init1: 302 opt: 426  Z-score: 360.5  bits: 76.9 E(85289): 2.4e-13
Smith-Waterman score: 602; 31.0% identity (55.2% similar) in 449 aa overlap (111-552:127-522)

               90       100       110       120       130       140
pF1KB8 KFVPAEARTGLLSFEESQRIKKLHEENKQFLCIPRRPNWNQNTTPEELKQAEKDNFLEWR
                                     : .:::: :. . . :.: . :. .: .. 
NP_005 KRAAREQVLQPVSAELLELDIREVYQPGSVLDFPRRPPWSYEMSKEQLMSQEERSFQDYL
        100       110       120       130       140       150      

              150       160       170       180       190       200
pF1KB8 RQLVRLEEEQKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKE
        ..      .::  . ::.::. :::::::.: ::::. :.: :.:..     :  ::  
NP_005 GKIHGAYSSEKL--SYFEHNLETWRQLWRVLEMSDIVLLITDIRHPVVNFPPALYEYVTG
        160         170       180       190       200       210    

              210       220       230         240         250      
pF1KB8 MDANKENVILINKADLLTAEQRSAWAMYFEKE--DVKVIFWSALA--GAIPLNGDSEEEA
        . .   :...::.::       ::  ::...  ...:......      : . .:  . 
NP_005 -ELGLALVLVLNKVDLAPPALVVAWKHYFHQHYPQLHVVLFTSFPRDPRTPQDPSSVLKK
           220       230       240       250       260       270   

        260       270       280       290       300       310      
pF1KB8 NRDDRQSNTTEFGHSSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPEEEED
       .:   .. :  .:  .. .:     :.  .   :  :  :. . :   . . .   :::.
NP_005 SRRRGRGWTRALGPEQLLRA----CEAITVGKVDLSSWREKIARDVAGATWGNGSGEEEE
           280       290           300       310       320         

        320       330       340       350       360       370      
pF1KB8 DWQTCSEEDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKEL
             :::::                                 . :: .:    .    
NP_005 ------EEDGP---------------------------------AVLVEQQTDSAMEPTG
           330                                        340       350

        380       390       400       410       420       430      
pF1KB8 HTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLC
        : .. ::: .:.: ::.::::::: :: ..: : :::: :::::..::: .. :.. ::
NP_005 PTQERYKDGVVTIGCVGFPNVGKSSLINGLVGRKVVSVSRTPGHTRYFQTYFLTPSVKLC
              360       370       380       390       400       410

        440       450       460       470       480       490      
pF1KB8 DCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPRE
       :::::..::..  . ..  .:: :: :...    :. . . :: ..:     ...  : :
NP_005 DCPGLIFPSLLPRQLQVL-AGIYPIAQIQEPYTAVGYLASRIPVQAL-----LHLRHP-E
              420        430       440       450            460    

        500         510       520        530       540       550   
pF1KB8 DEDP--HRPPTSEELLTAYGYMRGFMTAHG-QPDQPRSARYILKDYVSGKLLYCHPPPGR
        :::  ..:  . ..  :..  ::. ::.. . :  :.:  .:.  :.:.:  :  ::: 
NP_005 AEDPSAEHPWCAWDICEAWAEKRGYKTAKAARNDVYRAANSLLRLAVDGRLSLCFHPPGY
           470       480       490       500       510       520   

           560       570       580       590       600       610   
pF1KB8 DPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVM
                                                                   
NP_005 SEQKGTWESHPETTELVVLQGRVGPAGDEEEEEEEELSSSCEEEGEEDRDADEEGEGDEE
           530       540       550       560       570       580   

>>XP_005249072 (OMIM: 143024) PREDICTED: guanine nucleot  (607 aa)
 initn: 560 init1: 302 opt: 426  Z-score: 360.5  bits: 76.9 E(85289): 2.4e-13
Smith-Waterman score: 602; 31.0% identity (55.2% similar) in 449 aa overlap (111-552:127-522)

               90       100       110       120       130       140
pF1KB8 KFVPAEARTGLLSFEESQRIKKLHEENKQFLCIPRRPNWNQNTTPEELKQAEKDNFLEWR
                                     : .:::: :. . . :.: . :. .: .. 
XP_005 KRAAREQVLQPVSAELLELDIREVYQPGSVLDFPRRPPWSYEMSKEQLMSQEERSFQDYL
        100       110       120       130       140       150      

              150       160       170       180       190       200
pF1KB8 RQLVRLEEEQKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKE
        ..      .::  . ::.::. :::::::.: ::::. :.: :.:..     :  ::  
XP_005 GKIHGAYSSEKL--SYFEHNLETWRQLWRVLEMSDIVLLITDIRHPVVNFPPALYEYVTG
        160         170       180       190       200       210    

              210       220       230         240         250      
pF1KB8 MDANKENVILINKADLLTAEQRSAWAMYFEKE--DVKVIFWSALA--GAIPLNGDSEEEA
        . .   :...::.::       ::  ::...  ...:......      : . .:  . 
XP_005 -ELGLALVLVLNKVDLAPPALVVAWKHYFHQHYPQLHVVLFTSFPRDPRTPQDPSSVLKK
           220       230       240       250       260       270   

        260       270       280       290       300       310      
pF1KB8 NRDDRQSNTTEFGHSSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPEEEED
       .:   .. :  .:  .. .:     :.  .   :  :  :. . :   . . .   :::.
XP_005 SRRRGRGWTRALGPEQLLRA----CEAITVGKVDLSSWREKIARDVAGATWGNGSGEEEE
           280       290           300       310       320         

        320       330       340       350       360       370      
pF1KB8 DWQTCSEEDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKEL
             :::::                                 . :: .:    .    
XP_005 ------EEDGP---------------------------------AVLVEQQTDSAMEPTG
           330                                        340       350

        380       390       400       410       420       430      
pF1KB8 HTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLC
        : .. ::: .:.: ::.::::::: :: ..: : :::: :::::..::: .. :.. ::
XP_005 PTQERYKDGVVTIGCVGFPNVGKSSLINGLVGRKVVSVSRTPGHTRYFQTYFLTPSVKLC
              360       370       380       390       400       410

        440       450       460       470       480       490      
pF1KB8 DCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPRE
       :::::..::..  . ..  .:: :: :...    :. . . :: ..:     ...  : :
XP_005 DCPGLIFPSLLPRQLQVL-AGIYPIAQIQEPYTAVGYLASRIPVQAL-----LHLRHP-E
              420        430       440       450            460    

        500         510       520        530       540       550   
pF1KB8 DEDP--HRPPTSEELLTAYGYMRGFMTAHG-QPDQPRSARYILKDYVSGKLLYCHPPPGR
        :::  ..:  . ..  :..  ::. ::.. . :  :.:  .:.  :.:.:  :  ::: 
XP_005 AEDPSAEHPWCAWDICEAWAEKRGYKTAKAARNDVYRAANSLLRLAVDGRLSLCFHPPGY
           470       480       490       500       510       520   

           560       570       580       590       600       610   
pF1KB8 DPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVM
                                                                   
XP_005 SEQKGTWESHPETTELVVLQGRVGPAGDEEEEEEEELSSSCEEEGEEDRDADEEGEGDEE
           530       540       550       560       570       580   

>>NP_001310553 (OMIM: 609365) nucleolar GTP-binding prot  (548 aa)
 initn: 336 init1: 191 opt: 246  Z-score: 213.3  bits: 49.5 E(85289): 3.9e-05
Smith-Waterman score: 298; 28.6% identity (61.9% similar) in 189 aa overlap (368-556:113-285)

       340       350       360       370       380       390       
pF1KB8 ESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNV
                                     .::. : .::: .:    :..::..:::::
NP_001 KRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKK----QISVGFIGYPNV
             90       100       110       120           130        

       400       410       420       430       440       450       
pF1KB8 GKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSG
       ::::.:::. ..:  .:.   :.:: .: . .   . : ::::.:.::  ....... .:
NP_001 GKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSE-DSETDIVLKG
      140       150       160       170       180        190       

       460       470       480       490       500       510       
pF1KB8 ILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMR
       .. ......    .. : .    . .  :: :.     :.        .:..:   ..  
NP_001 VVQVEKIKSPEDHIGAVLERAKPEYISKTYKID---SWEN--------AEDFLEKLAFRT
       200       210       220       230                  240      

       520       530       540       550       560       570       
pF1KB8 GFMTAHGQPDQPRSARYILKDYVSGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKM
       : .   :.::    ....:.:.  :.. .   ::. .:.                     
NP_001 GKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSSSLEVVPEAAQNN
        250       260       270       280       290       300      

       580       590       600       610       620       630       
pF1KB8 QLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVMGYKPGSGVVTASTASSENGAGKPW
                                                                   
NP_001 PGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDDLVP
        310       320       330       340       350       360      

>>NP_037417 (OMIM: 609365) nucleolar GTP-binding protein  (731 aa)
 initn: 336 init1: 191 opt: 246  Z-score: 211.4  bits: 49.6 E(85289): 4.9e-05
Smith-Waterman score: 298; 28.6% identity (61.9% similar) in 189 aa overlap (368-556:296-468)

       340       350       360       370       380       390       
pF1KB8 ESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNV
                                     .::. : .::: .:    :..::..:::::
NP_037 KRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKK----QISVGFIGYPNV
         270       280       290       300           310       320 

       400       410       420       430       440       450       
pF1KB8 GKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSG
       ::::.:::. ..:  .:.   :.:: .: . .   . : ::::.:.::  ....... .:
NP_037 GKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSE-DSETDIVLKG
             330       340       350       360       370        380

       460       470       480       490       500       510       
pF1KB8 ILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMR
       .. ......    .. : .    . .  :: :.     :.        .:..:   ..  
NP_037 VVQVEKIKSPEDHIGAVLERAKPEYISKTYKID---SWEN--------AEDFLEKLAFRT
              390       400       410                  420         

       520       530       540       550       560       570       
pF1KB8 GFMTAHGQPDQPRSARYILKDYVSGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKM
       : .   :.::    ....:.:.  :.. .   ::. .:.                     
NP_037 GKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSSSLEVVPEAAQNN
     430       440       450       460       470       480         

       580       590       600       610       620       630       
pF1KB8 QLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVMGYKPGSGVVTASTASSENGAGKPW
                                                                   
NP_037 PGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDDLVP
     490       500       510       520       530       540         

>>NP_001310552 (OMIM: 609365) nucleolar GTP-binding prot  (799 aa)
 initn: 310 init1: 191 opt: 230  Z-score: 197.7  bits: 47.2 E(85289): 0.00028
Smith-Waterman score: 368; 23.7% identity (50.6% similar) in 443 aa overlap (120-556:166-536)

      90       100       110       120       130       140         
pF1KB8 GLLSFEESQRIKKLHEENKQFLCIPRRPNWNQNTTPEELKQAEKDNFLEWRRQLVRLEEE
                                     : . . :   :. ::  :  .   :: : .
NP_001 DTESFETTFGPKSQRKRPNLFASDMQSLIENAEMSTESYDQG-KDRDLVTEDTGVRNEAQ
         140       150       160       170        180       190    

     150       160       170       180       190       200         
pF1KB8 QKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEMDANKENVI
       ...      . .  : .:..::. ::.:::..:::.:.  :   .: :.:.    :. ..
NP_001 EEIYKKGQSKRI--WGELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKHLIF
          200         210       220       230       240       250  

     210       220       230       240       250       260         
pF1KB8 LINKADLLTAEQRSAWAMYFEKEDVKVIFWSALAGAIPLNGDSEEEANRDDRQSNTTEFG
       ..:: ::. .   . :.  . ..   . : ..:                      :. ::
NP_001 VLNKCDLVPTWATKRWVAVLSQDYPTLAFHASL----------------------TNPFG
            260       270       280                             290

     270       280       290       300       310       320         
pF1KB8 HSSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPEEEEDDWQTCS------E
       ...: :   . ..  ::  .   .:   :           ::      :. ::      :
NP_001 KGAFIQLLRQFGKPWHLTFH---ALLGFPGL-----LCILCP------WSPCSFYVLWLE
              300       310               320             330      

           330       340       350       360       370       380   
pF1KB8 EDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVK
       .  :: .    .   ...:   .:. . : .              .:.    ::: .:  
NP_001 RALPKFK---LQIPGQTSAPEGSRGTRLPYQ--------------ILKASCSLHTDKK--
        340          350       360                     370         

           390       400       410       420       430       440   
pF1KB8 DGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVM
         :..::..:::::::::.:::. ..:  .:.   :.:: .: . .   . : ::::.:.
NP_001 --QISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVY
         380       390       400       410       420       430     

           450       460       470       480       490       500   
pF1KB8 PSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRP
       ::  ....... .:.. ......    .. : .    . .  :: :.             
NP_001 PSE-DSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYISKTYKID-----------SW
          440       450       460       470       480              

           510       520       530       540       550       560   
pF1KB8 PTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKDYVSGKLLYCHPPPGRDPVTFQHQHQ
        ..:..:   ..  : .   :.::    ....:.:.  :.. .   ::. .:.       
NP_001 ENAEDFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLP
           490       500       510       520       530       540   

           570       580       590       600       610       620   
pF1KB8 RLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVMGYKPGSGVVT
                                                                   
NP_001 SSSLEVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGK
           550       560       570       580       590       600   

>>NP_001171748 (OMIM: 300873) guanine nucleotide-binding  (582 aa)
 initn: 383 init1: 171 opt: 194  Z-score: 170.2  bits: 41.6 E(85289): 0.0097
Smith-Waterman score: 265; 31.9% identity (59.0% similar) in 166 aa overlap (386-551:252-404)

         360       370       380       390       400       410     
pF1KB8 QIHNFSHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVS
                                     .. ::.:: ::::::: ::..  ..  ::.
NP_001 ESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVG
             230       240       250       260       270       280 

         420       430       440       450       460       470     
pF1KB8 ATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVC
       :.:: :: .: .:..  . : : ::.: :.  ....     . . .... : : ::  . 
NP_001 AVPGITKFMQEVYLDKFIRLLDAPGIV-PG-PNSEVGTILRNCVHVQKLADPVTPVETIL
             290       300        310        320       330         

         480       490       500       510       520       530     
pF1KB8 QNIPRHVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMRGFMTAHGQPDQPRSARYI
       :    . .   ::.. .            :.:..::: ..  :     :  .: ..:. .
NP_001 QRCNLEEISNYYGVSGFQ-----------TTEHFLTAVAHRLGKKKKGGLYSQEQAAKAV
     340       350                  360       370       380        

         540       550       560       570       580       590     
pF1KB8 LKDYVSGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKT
       : :.::::. .  :::                                            
NP_001 LADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANEDTMECLATGESDE
      390       400       410       420       430       440        

>>NP_061940 (OMIM: 300873) guanine nucleotide-binding pr  (582 aa)
 initn: 383 init1: 171 opt: 194  Z-score: 170.2  bits: 41.6 E(85289): 0.0097
Smith-Waterman score: 265; 31.9% identity (59.0% similar) in 166 aa overlap (386-551:252-404)

         360       370       380       390       400       410     
pF1KB8 QIHNFSHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVS
                                     .. ::.:: ::::::: ::..  ..  ::.
NP_061 ESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVG
             230       240       250       260       270       280 

         420       430       440       450       460       470     
pF1KB8 ATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVC
       :.:: :: .: .:..  . : : ::.: :.  ....     . . .... : : ::  . 
NP_061 AVPGITKFMQEVYLDKFIRLLDAPGIV-PG-PNSEVGTILRNCVHVQKLADPVTPVETIL
             290       300        310        320       330         

         480       490       500       510       520       530     
pF1KB8 QNIPRHVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMRGFMTAHGQPDQPRSARYI
       :    . .   ::.. .            :.:..::: ..  :     :  .: ..:. .
NP_061 QRCNLEEISNYYGVSGFQ-----------TTEHFLTAVAHRLGKKKKGGLYSQEQAAKAV
     340       350                  360       370       380        

         540       550       560       570       580       590     
pF1KB8 LKDYVSGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKT
       : :.::::. .  :::                                            
NP_061 LADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANEDTMECLATGESDE
      390       400       410       420       430       440        




658 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 09:14:32 2016 done: Sat Nov  5 09:14:34 2016
 Total Scan time: 11.590 Total Display time:  0.080

Function used was FASTA [36.3.4 Apr, 2011]
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