FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8659, 658 aa 1>>>pF1KB8659 658 - 658 aa - 658 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8444+/-0.000378; mu= 7.7564+/- 0.023 mean_var=148.1067+/-30.209, 0's: 0 Z-trim(117.7): 17 B-trim: 789 in 2/51 Lambda= 0.105387 statistics sampled from 29947 (29961) to 29947 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.351), width: 16 Scan time: 11.590 The best scores are: opt bits E(85289) NP_060855 (OMIM: 610780) large subunit GTPase 1 ho ( 658) 4464 690.9 4e-198 XP_016862285 (OMIM: 610780) PREDICTED: large subun ( 500) 3289 512.1 1.9e-144 NP_005266 (OMIM: 143024) guanine nucleotide-bindin ( 607) 426 76.9 2.4e-13 XP_005249072 (OMIM: 143024) PREDICTED: guanine nuc ( 607) 426 76.9 2.4e-13 NP_001310553 (OMIM: 609365) nucleolar GTP-binding ( 548) 246 49.5 3.9e-05 NP_037417 (OMIM: 609365) nucleolar GTP-binding pro ( 731) 246 49.6 4.9e-05 NP_001310552 (OMIM: 609365) nucleolar GTP-binding ( 799) 230 47.2 0.00028 NP_001171748 (OMIM: 300873) guanine nucleotide-bin ( 582) 194 41.6 0.0097 NP_061940 (OMIM: 300873) guanine nucleotide-bindin ( 582) 194 41.6 0.0097 >>NP_060855 (OMIM: 610780) large subunit GTPase 1 homolo (658 aa) initn: 4464 init1: 4464 opt: 4464 Z-score: 3678.0 bits: 690.9 E(85289): 4e-198 Smith-Waterman score: 4464; 99.8% identity (100.0% similar) in 658 aa overlap (1-658:1-658) 10 20 30 40 50 60 pF1KB8 MGRRRAPAGGSLGRALMRHQTQRSRSHRHTDSWLHTSELNDGYDWGRLNLQSVTEQSSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MGRRRAPAGGSLGRALMRHQTQRSRSHRHTDSWLHTSELNDGYDWGRLNLQSVTEQSSLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DFLATAELAGTEFVAEKLNIKFVPAEARTGLLSFEESQRIKKLHEENKQFLCIPRRPNWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 DFLATAELAGTEFVAEKLNIKFVPAEARTGLLSFEESQRIKKLHEENKQFLCIPRRPNWN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QNTTPEELKQAEKDNFLEWRRQLVRLEEEQKLILTPFERNLDFWRQLWRVIERSDIVVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 QNTTPEELKQAEKDNFLEWRRQLVRLEEEQKLILTPFERNLDFWRQLWRVIERSDIVVQI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VDARNPLLFRCEDLECYVKEMDANKENVILINKADLLTAEQRSAWAMYFEKEDVKVIFWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 VDARNPLLFRCEDLECYVKEMDANKENVILINKADLLTAEQRSAWAMYFEKEDVKVIFWS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ALAGAIPLNGDSEEEANRDDRQSNTTEFGHSSFDQAEISHSESEHLPARDSPSLSENPTT ::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::: NP_060 ALAGAIPLNGDSEEEANRDDRQSNTTKFGHSSFDQAEISHSESEHLPARDSPSLSENPTT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 DEDDSEYEDCPEEEEDDWQTCSEEDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 DEDDSEYEDCPEEEEDDWQTCSEEDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 TKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 TKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 HVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKDYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 HVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKDYV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 SGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQE 550 560 570 580 590 600 610 620 630 640 650 pF1KB8 NVRALTKGVQAVMGYKPGSGVVTASTASSENGAGKPWKKHGNRNKKEKSRRLYKHLDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 NVRALTKGVQAVMGYKPGSGVVTASTASSENGAGKPWKKHGNRNKKEKSRRLYKHLDM 610 620 630 640 650 >>XP_016862285 (OMIM: 610780) PREDICTED: large subunit G (500 aa) initn: 3289 init1: 3289 opt: 3289 Z-score: 2714.3 bits: 512.1 E(85289): 1.9e-144 Smith-Waterman score: 3289; 99.6% identity (100.0% similar) in 485 aa overlap (174-658:16-500) 150 160 170 180 190 200 pF1KB8 VRLEEEQKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEMDA .::::::::::::::::::::::::::::: XP_016 MEEVGLAIPASAGQPNDIVVQIVDARNPLLFRCEDLECYVKEMDA 10 20 30 40 210 220 230 240 250 260 pF1KB8 NKENVILINKADLLTAEQRSAWAMYFEKEDVKVIFWSALAGAIPLNGDSEEEANRDDRQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKENVILINKADLLTAEQRSAWAMYFEKEDVKVIFWSALAGAIPLNGDSEEEANRDDRQS 50 60 70 80 90 100 270 280 290 300 310 320 pF1KB8 NTTEFGHSSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPEEEEDDWQTCSE :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTTKFGHSSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPEEEEDDWQTCSE 110 120 130 140 150 160 330 340 350 360 370 380 pF1KB8 EDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVK 170 180 190 200 210 220 390 400 410 420 430 440 pF1KB8 DGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVM 230 240 250 260 270 280 450 460 470 480 490 500 pF1KB8 PSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRP 290 300 310 320 330 340 510 520 530 540 550 560 pF1KB8 PTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKDYVSGKLLYCHPPPGRDPVTFQHQHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKDYVSGKLLYCHPPPGRDPVTFQHQHQ 350 360 370 380 390 400 570 580 590 600 610 620 pF1KB8 RLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVMGYKPGSGVVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVMGYKPGSGVVT 410 420 430 440 450 460 630 640 650 pF1KB8 ASTASSENGAGKPWKKHGNRNKKEKSRRLYKHLDM ::::::::::::::::::::::::::::::::::: XP_016 ASTASSENGAGKPWKKHGNRNKKEKSRRLYKHLDM 470 480 490 500 >>NP_005266 (OMIM: 143024) guanine nucleotide-binding pr (607 aa) initn: 560 init1: 302 opt: 426 Z-score: 360.5 bits: 76.9 E(85289): 2.4e-13 Smith-Waterman score: 602; 31.0% identity (55.2% similar) in 449 aa overlap (111-552:127-522) 90 100 110 120 130 140 pF1KB8 KFVPAEARTGLLSFEESQRIKKLHEENKQFLCIPRRPNWNQNTTPEELKQAEKDNFLEWR : .:::: :. . . :.: . :. .: .. NP_005 KRAAREQVLQPVSAELLELDIREVYQPGSVLDFPRRPPWSYEMSKEQLMSQEERSFQDYL 100 110 120 130 140 150 150 160 170 180 190 200 pF1KB8 RQLVRLEEEQKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKE .. .:: . ::.::. :::::::.: ::::. :.: :.:.. : :: NP_005 GKIHGAYSSEKL--SYFEHNLETWRQLWRVLEMSDIVLLITDIRHPVVNFPPALYEYVTG 160 170 180 190 200 210 210 220 230 240 250 pF1KB8 MDANKENVILINKADLLTAEQRSAWAMYFEKE--DVKVIFWSALA--GAIPLNGDSEEEA . . :...::.:: :: ::... ...:...... : . .: . NP_005 -ELGLALVLVLNKVDLAPPALVVAWKHYFHQHYPQLHVVLFTSFPRDPRTPQDPSSVLKK 220 230 240 250 260 270 260 270 280 290 300 310 pF1KB8 NRDDRQSNTTEFGHSSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPEEEED .: .. : .: .. .: :. . : : :. . : . . . :::. NP_005 SRRRGRGWTRALGPEQLLRA----CEAITVGKVDLSSWREKIARDVAGATWGNGSGEEEE 280 290 300 310 320 320 330 340 350 360 370 pF1KB8 DWQTCSEEDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKEL ::::: . :: .: . NP_005 ------EEDGP---------------------------------AVLVEQQTDSAMEPTG 330 340 350 380 390 400 410 420 430 pF1KB8 HTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLC : .. ::: .:.: ::.::::::: :: ..: : :::: :::::..::: .. :.. :: NP_005 PTQERYKDGVVTIGCVGFPNVGKSSLINGLVGRKVVSVSRTPGHTRYFQTYFLTPSVKLC 360 370 380 390 400 410 440 450 460 470 480 490 pF1KB8 DCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPRE :::::..::.. . .. .:: :: :... :. . . :: ..: ... : : NP_005 DCPGLIFPSLLPRQLQVL-AGIYPIAQIQEPYTAVGYLASRIPVQAL-----LHLRHP-E 420 430 440 450 460 500 510 520 530 540 550 pF1KB8 DEDP--HRPPTSEELLTAYGYMRGFMTAHG-QPDQPRSARYILKDYVSGKLLYCHPPPGR ::: ..: . .. :.. ::. ::.. . : :.: .:. :.:.: : ::: NP_005 AEDPSAEHPWCAWDICEAWAEKRGYKTAKAARNDVYRAANSLLRLAVDGRLSLCFHPPGY 470 480 490 500 510 520 560 570 580 590 600 610 pF1KB8 DPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVM NP_005 SEQKGTWESHPETTELVVLQGRVGPAGDEEEEEEEELSSSCEEEGEEDRDADEEGEGDEE 530 540 550 560 570 580 >>XP_005249072 (OMIM: 143024) PREDICTED: guanine nucleot (607 aa) initn: 560 init1: 302 opt: 426 Z-score: 360.5 bits: 76.9 E(85289): 2.4e-13 Smith-Waterman score: 602; 31.0% identity (55.2% similar) in 449 aa overlap (111-552:127-522) 90 100 110 120 130 140 pF1KB8 KFVPAEARTGLLSFEESQRIKKLHEENKQFLCIPRRPNWNQNTTPEELKQAEKDNFLEWR : .:::: :. . . :.: . :. .: .. XP_005 KRAAREQVLQPVSAELLELDIREVYQPGSVLDFPRRPPWSYEMSKEQLMSQEERSFQDYL 100 110 120 130 140 150 150 160 170 180 190 200 pF1KB8 RQLVRLEEEQKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKE .. .:: . ::.::. :::::::.: ::::. :.: :.:.. : :: XP_005 GKIHGAYSSEKL--SYFEHNLETWRQLWRVLEMSDIVLLITDIRHPVVNFPPALYEYVTG 160 170 180 190 200 210 210 220 230 240 250 pF1KB8 MDANKENVILINKADLLTAEQRSAWAMYFEKE--DVKVIFWSALA--GAIPLNGDSEEEA . . :...::.:: :: ::... ...:...... : . .: . XP_005 -ELGLALVLVLNKVDLAPPALVVAWKHYFHQHYPQLHVVLFTSFPRDPRTPQDPSSVLKK 220 230 240 250 260 270 260 270 280 290 300 310 pF1KB8 NRDDRQSNTTEFGHSSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPEEEED .: .. : .: .. .: :. . : : :. . : . . . :::. XP_005 SRRRGRGWTRALGPEQLLRA----CEAITVGKVDLSSWREKIARDVAGATWGNGSGEEEE 280 290 300 310 320 320 330 340 350 360 370 pF1KB8 DWQTCSEEDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKEL ::::: . :: .: . XP_005 ------EEDGP---------------------------------AVLVEQQTDSAMEPTG 330 340 350 380 390 400 410 420 430 pF1KB8 HTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLC : .. ::: .:.: ::.::::::: :: ..: : :::: :::::..::: .. :.. :: XP_005 PTQERYKDGVVTIGCVGFPNVGKSSLINGLVGRKVVSVSRTPGHTRYFQTYFLTPSVKLC 360 370 380 390 400 410 440 450 460 470 480 490 pF1KB8 DCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPRE :::::..::.. . .. .:: :: :... :. . . :: ..: ... : : XP_005 DCPGLIFPSLLPRQLQVL-AGIYPIAQIQEPYTAVGYLASRIPVQAL-----LHLRHP-E 420 430 440 450 460 500 510 520 530 540 550 pF1KB8 DEDP--HRPPTSEELLTAYGYMRGFMTAHG-QPDQPRSARYILKDYVSGKLLYCHPPPGR ::: ..: . .. :.. ::. ::.. . : :.: .:. :.:.: : ::: XP_005 AEDPSAEHPWCAWDICEAWAEKRGYKTAKAARNDVYRAANSLLRLAVDGRLSLCFHPPGY 470 480 490 500 510 520 560 570 580 590 600 610 pF1KB8 DPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVM XP_005 SEQKGTWESHPETTELVVLQGRVGPAGDEEEEEEEELSSSCEEEGEEDRDADEEGEGDEE 530 540 550 560 570 580 >>NP_001310553 (OMIM: 609365) nucleolar GTP-binding prot (548 aa) initn: 336 init1: 191 opt: 246 Z-score: 213.3 bits: 49.5 E(85289): 3.9e-05 Smith-Waterman score: 298; 28.6% identity (61.9% similar) in 189 aa overlap (368-556:113-285) 340 350 360 370 380 390 pF1KB8 ESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNV .::. : .::: .: :..::..::::: NP_001 KRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKK----QISVGFIGYPNV 90 100 110 120 130 400 410 420 430 440 450 pF1KB8 GKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSG ::::.:::. ..: .:. :.:: .: . . . : ::::.:.:: ....... .: NP_001 GKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSE-DSETDIVLKG 140 150 160 170 180 190 460 470 480 490 500 510 pF1KB8 ILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMR .. ...... .. : . . . :: :. :. .:..: .. NP_001 VVQVEKIKSPEDHIGAVLERAKPEYISKTYKID---SWEN--------AEDFLEKLAFRT 200 210 220 230 240 520 530 540 550 560 570 pF1KB8 GFMTAHGQPDQPRSARYILKDYVSGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKM : . :.:: ....:.:. :.. . ::. .:. NP_001 GKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSSSLEVVPEAAQNN 250 260 270 280 290 300 580 590 600 610 620 630 pF1KB8 QLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVMGYKPGSGVVTASTASSENGAGKPW NP_001 PGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDDLVP 310 320 330 340 350 360 >>NP_037417 (OMIM: 609365) nucleolar GTP-binding protein (731 aa) initn: 336 init1: 191 opt: 246 Z-score: 211.4 bits: 49.6 E(85289): 4.9e-05 Smith-Waterman score: 298; 28.6% identity (61.9% similar) in 189 aa overlap (368-556:296-468) 340 350 360 370 380 390 pF1KB8 ESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNV .::. : .::: .: :..::..::::: NP_037 KRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKK----QISVGFIGYPNV 270 280 290 300 310 320 400 410 420 430 440 450 pF1KB8 GKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSG ::::.:::. ..: .:. :.:: .: . . . : ::::.:.:: ....... .: NP_037 GKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSE-DSETDIVLKG 330 340 350 360 370 380 460 470 480 490 500 510 pF1KB8 ILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMR .. ...... .. : . . . :: :. :. .:..: .. NP_037 VVQVEKIKSPEDHIGAVLERAKPEYISKTYKID---SWEN--------AEDFLEKLAFRT 390 400 410 420 520 530 540 550 560 570 pF1KB8 GFMTAHGQPDQPRSARYILKDYVSGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKM : . :.:: ....:.:. :.. . ::. .:. NP_037 GKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSSSLEVVPEAAQNN 430 440 450 460 470 480 580 590 600 610 620 630 pF1KB8 QLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVMGYKPGSGVVTASTASSENGAGKPW NP_037 PGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDDLVP 490 500 510 520 530 540 >>NP_001310552 (OMIM: 609365) nucleolar GTP-binding prot (799 aa) initn: 310 init1: 191 opt: 230 Z-score: 197.7 bits: 47.2 E(85289): 0.00028 Smith-Waterman score: 368; 23.7% identity (50.6% similar) in 443 aa overlap (120-556:166-536) 90 100 110 120 130 140 pF1KB8 GLLSFEESQRIKKLHEENKQFLCIPRRPNWNQNTTPEELKQAEKDNFLEWRRQLVRLEEE : . . : :. :: : . :: : . NP_001 DTESFETTFGPKSQRKRPNLFASDMQSLIENAEMSTESYDQG-KDRDLVTEDTGVRNEAQ 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB8 QKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEMDANKENVI ... . . : .:..::. ::.:::..:::.:. : .: :.:. :. .. NP_001 EEIYKKGQSKRI--WGELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKHLIF 200 210 220 230 240 250 210 220 230 240 250 260 pF1KB8 LINKADLLTAEQRSAWAMYFEKEDVKVIFWSALAGAIPLNGDSEEEANRDDRQSNTTEFG ..:: ::. . . :. . .. . : ..: :. :: NP_001 VLNKCDLVPTWATKRWVAVLSQDYPTLAFHASL----------------------TNPFG 260 270 280 290 270 280 290 300 310 320 pF1KB8 HSSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPEEEEDDWQTCS------E ...: : . .. :: . .: : :: :. :: : NP_001 KGAFIQLLRQFGKPWHLTFH---ALLGFPGL-----LCILCP------WSPCSFYVLWLE 300 310 320 330 330 340 350 360 370 380 pF1KB8 EDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVK . :: . . ...: .:. . : . .:. ::: .: NP_001 RALPKFK---LQIPGQTSAPEGSRGTRLPYQ--------------ILKASCSLHTDKK-- 340 350 360 370 390 400 410 420 430 440 pF1KB8 DGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVM :..::..:::::::::.:::. ..: .:. :.:: .: . . . : ::::.:. NP_001 --QISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVY 380 390 400 410 420 430 450 460 470 480 490 500 pF1KB8 PSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRP :: ....... .:.. ...... .. : . . . :: :. NP_001 PSE-DSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYISKTYKID-----------SW 440 450 460 470 480 510 520 530 540 550 560 pF1KB8 PTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKDYVSGKLLYCHPPPGRDPVTFQHQHQ ..:..: .. : . :.:: ....:.:. :.. . ::. .:. NP_001 ENAEDFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLP 490 500 510 520 530 540 570 580 590 600 610 620 pF1KB8 RLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVMGYKPGSGVVT NP_001 SSSLEVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGK 550 560 570 580 590 600 >>NP_001171748 (OMIM: 300873) guanine nucleotide-binding (582 aa) initn: 383 init1: 171 opt: 194 Z-score: 170.2 bits: 41.6 E(85289): 0.0097 Smith-Waterman score: 265; 31.9% identity (59.0% similar) in 166 aa overlap (386-551:252-404) 360 370 380 390 400 410 pF1KB8 QIHNFSHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVS .. ::.:: ::::::: ::.. .. ::. NP_001 ESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVG 230 240 250 260 270 280 420 430 440 450 460 470 pF1KB8 ATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVC :.:: :: .: .:.. . : : ::.: :. .... . . .... : : :: . NP_001 AVPGITKFMQEVYLDKFIRLLDAPGIV-PG-PNSEVGTILRNCVHVQKLADPVTPVETIL 290 300 310 320 330 480 490 500 510 520 530 pF1KB8 QNIPRHVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMRGFMTAHGQPDQPRSARYI : . . ::.. . :.:..::: .. : : .: ..:. . NP_001 QRCNLEEISNYYGVSGFQ-----------TTEHFLTAVAHRLGKKKKGGLYSQEQAAKAV 340 350 360 370 380 540 550 560 570 580 590 pF1KB8 LKDYVSGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKT : :.::::. . ::: NP_001 LADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANEDTMECLATGESDE 390 400 410 420 430 440 >>NP_061940 (OMIM: 300873) guanine nucleotide-binding pr (582 aa) initn: 383 init1: 171 opt: 194 Z-score: 170.2 bits: 41.6 E(85289): 0.0097 Smith-Waterman score: 265; 31.9% identity (59.0% similar) in 166 aa overlap (386-551:252-404) 360 370 380 390 400 410 pF1KB8 QIHNFSHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVS .. ::.:: ::::::: ::.. .. ::. NP_061 ESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVG 230 240 250 260 270 280 420 430 440 450 460 470 pF1KB8 ATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVC :.:: :: .: .:.. . : : ::.: :. .... . . .... : : :: . NP_061 AVPGITKFMQEVYLDKFIRLLDAPGIV-PG-PNSEVGTILRNCVHVQKLADPVTPVETIL 290 300 310 320 330 480 490 500 510 520 530 pF1KB8 QNIPRHVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMRGFMTAHGQPDQPRSARYI : . . ::.. . :.:..::: .. : : .: ..:. . NP_061 QRCNLEEISNYYGVSGFQ-----------TTEHFLTAVAHRLGKKKKGGLYSQEQAAKAV 340 350 360 370 380 540 550 560 570 580 590 pF1KB8 LKDYVSGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKT : :.::::. . ::: NP_061 LADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANEDTMECLATGESDE 390 400 410 420 430 440 658 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 09:14:32 2016 done: Sat Nov 5 09:14:34 2016 Total Scan time: 11.590 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]