FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8662, 377 aa 1>>>pF1KB8662 377 - 377 aa - 377 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.4467+/-0.000623; mu= -8.3363+/- 0.038 mean_var=301.7505+/-62.813, 0's: 0 Z-trim(113.7): 90 B-trim: 1037 in 2/53 Lambda= 0.073833 statistics sampled from 23052 (23139) to 23052 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.612), E-opt: 0.2 (0.271), width: 16 Scan time: 7.940 The best scores are: opt bits E(85289) NP_054876 (OMIM: 616070) coiled-coil domain-contai ( 377) 2370 266.6 6.9e-71 XP_011521340 (OMIM: 616070) PREDICTED: coiled-coil ( 350) 2161 244.3 3.3e-64 XP_011521341 (OMIM: 616070) PREDICTED: coiled-coil ( 332) 2093 237.0 4.8e-62 XP_011521343 (OMIM: 616070) PREDICTED: coiled-coil ( 332) 2093 237.0 4.8e-62 XP_011521342 (OMIM: 616070) PREDICTED: coiled-coil ( 332) 2093 237.0 4.8e-62 XP_016878665 (OMIM: 616070) PREDICTED: coiled-coil ( 332) 2093 237.0 4.8e-62 XP_011521344 (OMIM: 616070) PREDICTED: coiled-coil ( 310) 1856 211.8 1.8e-54 XP_016878666 (OMIM: 616070) PREDICTED: coiled-coil ( 289) 1807 206.5 6.3e-53 NP_001135774 (OMIM: 616070) coiled-coil domain-con ( 323) 1537 177.8 3.1e-44 XP_016878667 (OMIM: 616070) PREDICTED: coiled-coil ( 222) 1293 151.7 1.6e-36 >>NP_054876 (OMIM: 616070) coiled-coil domain-containing (377 aa) initn: 2370 init1: 2370 opt: 2370 Z-score: 1393.6 bits: 266.6 E(85289): 6.9e-71 Smith-Waterman score: 2370; 100.0% identity (100.0% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KB8 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 PPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 NAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 QELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 QELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 KAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWN 310 320 330 340 350 360 370 pF1KB8 RMKITNEQLQADYLAGK ::::::::::::::::: NP_054 RMKITNEQLQADYLAGK 370 >>XP_011521340 (OMIM: 616070) PREDICTED: coiled-coil dom (350 aa) initn: 2161 init1: 2161 opt: 2161 Z-score: 1273.8 bits: 244.3 E(85289): 3.3e-64 Smith-Waterman score: 2161; 100.0% identity (100.0% similar) in 344 aa overlap (34-377:7-350) 10 20 30 40 50 60 pF1KB8 DESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPR :::::::::::::::::::::::::::::: XP_011 MHYRRWSYVNSALKTETEMFEKYYAKLEPRDQRPPR 10 20 30 70 80 90 100 110 120 pF1KB8 LSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAE 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB8 RDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRD 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB8 NMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQEL 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB8 TQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAE 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB8 AVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMK 280 290 300 310 320 330 370 pF1KB8 ITNEQLQADYLAGK :::::::::::::: XP_011 ITNEQLQADYLAGK 340 350 >>XP_011521341 (OMIM: 616070) PREDICTED: coiled-coil dom (332 aa) initn: 2093 init1: 2093 opt: 2093 Z-score: 1234.9 bits: 237.0 E(85289): 4.8e-62 Smith-Waterman score: 2093; 100.0% identity (100.0% similar) in 332 aa overlap (46-377:1-332) 20 30 40 50 60 70 pF1KB8 GSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYA :::::::::::::::::::::::::::::: XP_011 MFEKYYAKLEPRDQRPPRLSEIKISAADYA 10 20 30 80 90 100 110 120 130 pF1KB8 QFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEE 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB8 AEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVS 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB8 LKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQ 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB8 VLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB8 FRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLA 280 290 300 310 320 330 pF1KB8 GK :: XP_011 GK >>XP_011521343 (OMIM: 616070) PREDICTED: coiled-coil dom (332 aa) initn: 2093 init1: 2093 opt: 2093 Z-score: 1234.9 bits: 237.0 E(85289): 4.8e-62 Smith-Waterman score: 2093; 100.0% identity (100.0% similar) in 332 aa overlap (46-377:1-332) 20 30 40 50 60 70 pF1KB8 GSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYA :::::::::::::::::::::::::::::: XP_011 MFEKYYAKLEPRDQRPPRLSEIKISAADYA 10 20 30 80 90 100 110 120 130 pF1KB8 QFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEE 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB8 AEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVS 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB8 LKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQ 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB8 VLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB8 FRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLA 280 290 300 310 320 330 pF1KB8 GK :: XP_011 GK >>XP_011521342 (OMIM: 616070) PREDICTED: coiled-coil dom (332 aa) initn: 2093 init1: 2093 opt: 2093 Z-score: 1234.9 bits: 237.0 E(85289): 4.8e-62 Smith-Waterman score: 2093; 100.0% identity (100.0% similar) in 332 aa overlap (46-377:1-332) 20 30 40 50 60 70 pF1KB8 GSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYA :::::::::::::::::::::::::::::: XP_011 MFEKYYAKLEPRDQRPPRLSEIKISAADYA 10 20 30 80 90 100 110 120 130 pF1KB8 QFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEE 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB8 AEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVS 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB8 LKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQ 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB8 VLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB8 FRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLA 280 290 300 310 320 330 pF1KB8 GK :: XP_011 GK >>XP_016878665 (OMIM: 616070) PREDICTED: coiled-coil dom (332 aa) initn: 2093 init1: 2093 opt: 2093 Z-score: 1234.9 bits: 237.0 E(85289): 4.8e-62 Smith-Waterman score: 2093; 100.0% identity (100.0% similar) in 332 aa overlap (46-377:1-332) 20 30 40 50 60 70 pF1KB8 GSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYA :::::::::::::::::::::::::::::: XP_016 MFEKYYAKLEPRDQRPPRLSEIKISAADYA 10 20 30 80 90 100 110 120 130 pF1KB8 QFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEE 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB8 AEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVS 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB8 LKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQ 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB8 VLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAE 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB8 FRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLA 280 290 300 310 320 330 pF1KB8 GK :: XP_016 GK >>XP_011521344 (OMIM: 616070) PREDICTED: coiled-coil dom (310 aa) initn: 1856 init1: 1856 opt: 1856 Z-score: 1098.9 bits: 211.8 E(85289): 1.8e-54 Smith-Waterman score: 1856; 100.0% identity (100.0% similar) in 297 aa overlap (1-297:1-297) 10 20 30 40 50 60 pF1KB8 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 QELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEETVS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWN XP_011 LYHSGWSAAS 310 >>XP_016878666 (OMIM: 616070) PREDICTED: coiled-coil dom (289 aa) initn: 1807 init1: 1807 opt: 1807 Z-score: 1071.1 bits: 206.5 E(85289): 6.3e-53 Smith-Waterman score: 1807; 100.0% identity (100.0% similar) in 289 aa overlap (89-377:1-289) 60 70 80 90 100 110 pF1KB8 QRPPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHT :::::::::::::::::::::::::::::: XP_016 MDRGVGLTADQKLELVQKEVADMKDDLRHT 10 20 30 120 130 140 150 160 170 pF1KB8 RANAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RANAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDM 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB8 NRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEA 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB8 RNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEED 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB8 RAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKA 220 230 240 250 260 270 360 370 pF1KB8 WNRMKITNEQLQADYLAGK ::::::::::::::::::: XP_016 WNRMKITNEQLQADYLAGK 280 >>NP_001135774 (OMIM: 616070) coiled-coil domain-contain (323 aa) initn: 1533 init1: 1533 opt: 1537 Z-score: 915.0 bits: 177.8 E(85289): 3.1e-44 Smith-Waterman score: 1896; 85.7% identity (85.7% similar) in 377 aa overlap (1-377:1-323) 10 20 30 40 50 60 pF1KB8 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRA :::::::::::::::: NP_001 PPRLSEIKISAADYAQ-------------------------------------------- 70 130 140 150 160 170 180 pF1KB8 NAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ----------AIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR 80 90 100 110 120 190 200 210 220 230 240 pF1KB8 RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARN 130 140 150 160 170 180 250 260 270 280 290 300 pF1KB8 QELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRA 190 200 210 220 230 240 310 320 330 340 350 360 pF1KB8 KAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWN 250 260 270 280 290 300 370 pF1KB8 RMKITNEQLQADYLAGK ::::::::::::::::: NP_001 RMKITNEQLQADYLAGK 310 320 >>XP_016878667 (OMIM: 616070) PREDICTED: coiled-coil dom (222 aa) initn: 1293 init1: 1293 opt: 1293 Z-score: 776.8 bits: 151.7 E(85289): 1.6e-36 Smith-Waterman score: 1293; 100.0% identity (100.0% similar) in 209 aa overlap (89-297:1-209) 60 70 80 90 100 110 pF1KB8 QRPPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHT :::::::::::::::::::::::::::::: XP_016 MDRGVGLTADQKLELVQKEVADMKDDLRHT 10 20 30 120 130 140 150 160 170 pF1KB8 RANAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RANAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDM 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB8 NRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEA 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB8 RNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEED ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEET 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB8 RAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKA XP_016 VSLYHSGWSAAS 220 377 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:20:05 2016 done: Fri Nov 4 14:20:06 2016 Total Scan time: 7.940 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]