Result of FASTA (omim) for pF1KB8663
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8663, 558 aa
  1>>>pF1KB8663 558 - 558 aa - 558 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.7588+/-0.000573; mu= -10.5983+/- 0.035
 mean_var=513.4569+/-104.149, 0's: 0 Z-trim(117.9): 150  B-trim: 0 in 0/55
 Lambda= 0.056601
 statistics sampled from 30092 (30234) to 30092 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.354), width:  16
 Scan time: 11.610

The best scores are:                                      opt bits E(85289)
NP_115517 (OMIM: 616173) nuclear speckle splicing  ( 558) 3688 316.5 1.4e-85
XP_016880698 (OMIM: 616173) PREDICTED: nuclear spe ( 588) 3427 295.2 3.7e-79
XP_011523647 (OMIM: 616173) PREDICTED: nuclear spe ( 537) 3425 295.0 3.9e-79
XP_016880700 (OMIM: 616173) PREDICTED: nuclear spe ( 504) 3335 287.6 6.2e-77
XP_016880699 (OMIM: 616173) PREDICTED: nuclear spe ( 504) 3335 287.6 6.2e-77
XP_016880702 (OMIM: 616173) PREDICTED: nuclear spe ( 504) 3335 287.6 6.2e-77
XP_016880701 (OMIM: 616173) PREDICTED: nuclear spe ( 504) 3335 287.6 6.2e-77
XP_016880704 (OMIM: 616173) PREDICTED: nuclear spe ( 504) 3335 287.6 6.2e-77
XP_016880703 (OMIM: 616173) PREDICTED: nuclear spe ( 504) 3335 287.6 6.2e-77
NP_001248396 (OMIM: 616173) nuclear speckle splici ( 504) 3335 287.6 6.2e-77
NP_055885 (OMIM: 616453) zinc finger CCCH domain-c (1564)  376 46.6 0.00071
XP_005266369 (OMIM: 616453) PREDICTED: zinc finger (1564)  376 46.6 0.00071
NP_001317496 (OMIM: 616453) zinc finger CCCH domai (1668)  376 46.6 0.00074
NP_001317494 (OMIM: 616453) zinc finger CCCH domai (1668)  376 46.6 0.00074
NP_001317495 (OMIM: 616453) zinc finger CCCH domai (1668)  376 46.6 0.00074
XP_016875966 (OMIM: 616453) PREDICTED: zinc finger (1669)  376 46.6 0.00074
XP_005266367 (OMIM: 616453) PREDICTED: zinc finger (1669)  376 46.6 0.00074
XP_016875968 (OMIM: 616453) PREDICTED: zinc finger (1669)  376 46.6 0.00074
XP_016875967 (OMIM: 616453) PREDICTED: zinc finger (1669)  376 46.6 0.00074
NP_001317493 (OMIM: 616453) zinc finger CCCH domai (1669)  376 46.6 0.00074
NP_001070256 (OMIM: 616453) zinc finger CCCH domai (1669)  376 46.6 0.00074
XP_016875969 (OMIM: 616453) PREDICTED: zinc finger (1669)  376 46.6 0.00074
NP_001310464 (OMIM: 609268) splicing regulatory gl ( 358)  328 41.9   0.004
NP_001310463 (OMIM: 609268) splicing regulatory gl ( 359)  325 41.7  0.0048
XP_016864545 (OMIM: 609268) PREDICTED: splicing re ( 359)  325 41.7  0.0048
NP_001257421 (OMIM: 609268) splicing regulatory gl ( 507)  328 42.1  0.0051
NP_001310458 (OMIM: 609268) splicing regulatory gl ( 623)  328 42.2  0.0058
NP_001310456 (OMIM: 609268) splicing regulatory gl ( 508)  325 41.9   0.006
NP_631907 (OMIM: 609268) splicing regulatory gluta ( 508)  325 41.9   0.006
XP_011541473 (OMIM: 609268) PREDICTED: splicing re ( 508)  325 41.9   0.006
NP_001070667 (OMIM: 609268) splicing regulatory gl ( 624)  325 42.0  0.0069


>>NP_115517 (OMIM: 616173) nuclear speckle splicing regu  (558 aa)
 initn: 3688 init1: 3688 opt: 3688  Z-score: 1657.5  bits: 316.5 E(85289): 1.4e-85
Smith-Waterman score: 3688; 100.0% identity (100.0% similar) in 558 aa overlap (1-558:1-558)

               10        20        30        40        50        60
pF1KB8 MAIPGRQYGLILPKKTQQLHPVLQKPSVFGNDSDDDDETSVSESLQREAAKKQAMKQTKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MAIPGRQYGLILPKKTQQLHPVLQKPSVFGNDSDDDDETSVSESLQREAAKKQAMKQTKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 EIQKALAEDATVYEYDSIYDEMQKKKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 EIQKALAEDATVYEYDSIYDEMQKKKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RMEKKIQREREMEKGEFDDKEAFVTSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 RMEKKIQREREMEKGEFDDKEAFVTSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 SGFYRHLLNQAVGEEEVPKCSFREARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 SGFYRHLLNQAVGEEEVPKCSFREARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 EENPDADSDFDAKSSADDEIEETRVNCRREKVIETPENDFKHHRSQNHSRSPSEERGHST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 EENPDADSDFDAKSSADDEIEETRVNCRREKVIETPENDFKHHRSQNHSRSPSEERGHST
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 RHHTKGSRTSRGHEKREDQHQQKQSRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 RHHTKGSRTSRGHEKREDQHQQKQSRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 QEDKPRARDQRERSDRVWKREKDREKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 QEDKPRARDQRERSDRVWKREKDREKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEH
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 MKVRKERYENNDKYRDREKREVGVQSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MKVRKERYENNDKYRDREKREVGVQSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 DKERNQEKPSNSESSLGAKHRLTEEGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 DKERNQEKPSNSESSLGAKHRLTEEGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYL
              490       500       510       520       530       540

              550        
pF1KB8 ARQMARVNAKTYIEKEDD
       ::::::::::::::::::
NP_115 ARQMARVNAKTYIEKEDD
              550        

>>XP_016880698 (OMIM: 616173) PREDICTED: nuclear speckle  (588 aa)
 initn: 3427 init1: 3427 opt: 3427  Z-score: 1542.1  bits: 295.2 E(85289): 3.7e-79
Smith-Waterman score: 3427; 99.8% identity (100.0% similar) in 521 aa overlap (38-558:68-588)

        10        20        30        40        50        60       
pF1KB8 YGLILPKKTQQLHPVLQKPSVFGNDSDDDDETSVSESLQREAAKKQAMKQTKLEIQKALA
                                     .:::::::::::::::::::::::::::::
XP_016 FKGKLLKFGIRVPELESCFAIHQLFVLKFSQTSVSESLQREAAKKQAMKQTKLEIQKALA
        40        50        60        70        80        90       

        70        80        90       100       110       120       
pF1KB8 EDATVYEYDSIYDEMQKKKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDATVYEYDSIYDEMQKKKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQ
       100       110       120       130       140       150       

       130       140       150       160       170       180       
pF1KB8 REREMEKGEFDDKEAFVTSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REREMEKGEFDDKEAFVTSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHL
       160       170       180       190       200       210       

       190       200       210       220       230       240       
pF1KB8 LNQAVGEEEVPKCSFREARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNQAVGEEEVPKCSFREARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDAD
       220       230       240       250       260       270       

       250       260       270       280       290       300       
pF1KB8 SDFDAKSSADDEIEETRVNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDFDAKSSADDEIEETRVNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGS
       280       290       300       310       320       330       

       310       320       330       340       350       360       
pF1KB8 RTSRGHEKREDQHQQKQSRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTSRGHEKREDQHQQKQSRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRA
       340       350       360       370       380       390       

       370       380       390       400       410       420       
pF1KB8 RDQRERSDRVWKREKDREKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDQRERSDRVWKREKDREKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKER
       400       410       420       430       440       450       

       430       440       450       460       470       480       
pF1KB8 YENNDKYRDREKREVGVQSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YENNDKYRDREKREVGVQSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQE
       460       470       480       490       500       510       

       490       500       510       520       530       540       
pF1KB8 KPSNSESSLGAKHRLTEEGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPSNSESSLGAKHRLTEEGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARV
       520       530       540       550       560       570       

       550        
pF1KB8 NAKTYIEKEDD
       :::::::::::
XP_016 NAKTYIEKEDD
       580        

>>XP_011523647 (OMIM: 616173) PREDICTED: nuclear speckle  (537 aa)
 initn: 3460 init1: 3425 opt: 3425  Z-score: 1541.6  bits: 295.0 E(85289): 3.9e-79
Smith-Waterman score: 3425; 100.0% identity (100.0% similar) in 520 aa overlap (39-558:18-537)

       10        20        30        40        50        60        
pF1KB8 GLILPKKTQQLHPVLQKPSVFGNDSDDDDETSVSESLQREAAKKQAMKQTKLEIQKALAE
                                     ::::::::::::::::::::::::::::::
XP_011              MAIPGRQNIVLRSHRKRTSVSESLQREAAKKQAMKQTKLEIQKALAE
                            10        20        30        40       

       70        80        90       100       110       120        
pF1KB8 DATVYEYDSIYDEMQKKKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DATVYEYDSIYDEMQKKKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQR
        50        60        70        80        90       100       

      130       140       150       160       170       180        
pF1KB8 EREMEKGEFDDKEAFVTSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EREMEKGEFDDKEAFVTSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLL
       110       120       130       140       150       160       

      190       200       210       220       230       240        
pF1KB8 NQAVGEEEVPKCSFREARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQAVGEEEVPKCSFREARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADS
       170       180       190       200       210       220       

      250       260       270       280       290       300        
pF1KB8 DFDAKSSADDEIEETRVNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFDAKSSADDEIEETRVNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSR
       230       240       250       260       270       280       

      310       320       330       340       350       360        
pF1KB8 TSRGHEKREDQHQQKQSRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSRGHEKREDQHQQKQSRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRAR
       290       300       310       320       330       340       

      370       380       390       400       410       420        
pF1KB8 DQRERSDRVWKREKDREKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQRERSDRVWKREKDREKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERY
       350       360       370       380       390       400       

      430       440       450       460       470       480        
pF1KB8 ENNDKYRDREKREVGVQSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENNDKYRDREKREVGVQSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEK
       410       420       430       440       450       460       

      490       500       510       520       530       540        
pF1KB8 PSNSESSLGAKHRLTEEGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSNSESSLGAKHRLTEEGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVN
       470       480       490       500       510       520       

      550        
pF1KB8 AKTYIEKEDD
       ::::::::::
XP_011 AKTYIEKEDD
       530       

>>XP_016880700 (OMIM: 616173) PREDICTED: nuclear speckle  (504 aa)
 initn: 3335 init1: 3335 opt: 3335  Z-score: 1502.3  bits: 287.6 E(85289): 6.2e-77
Smith-Waterman score: 3335; 100.0% identity (100.0% similar) in 504 aa overlap (55-558:1-504)

           30        40        50        60        70        80    
pF1KB8 KPSVFGNDSDDDDETSVSESLQREAAKKQAMKQTKLEIQKALAEDATVYEYDSIYDEMQK
                                     ::::::::::::::::::::::::::::::
XP_016                               MKQTKLEIQKALAEDATVYEYDSIYDEMQK
                                             10        20        30

           90       100       110       120       130       140    
pF1KB8 KKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFV
               40        50        60        70        80        90

          150       160       170       180       190       200    
pF1KB8 TSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFRE
              100       110       120       130       140       150

          210       220       230       240       250       260    
pF1KB8 ARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETR
              160       170       180       190       200       210

          270       280       290       300       310       320    
pF1KB8 VNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQ
              220       230       240       250       260       270

          330       340       350       360       370       380    
pF1KB8 SRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDR
              280       290       300       310       320       330

          390       400       410       420       430       440    
pF1KB8 EKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGV
              340       350       360       370       380       390

          450       460       470       480       490       500    
pF1KB8 QSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTE
              400       410       420       430       440       450

          510       520       530       540       550        
pF1KB8 EGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD
              460       470       480       490       500    

>>XP_016880699 (OMIM: 616173) PREDICTED: nuclear speckle  (504 aa)
 initn: 3335 init1: 3335 opt: 3335  Z-score: 1502.3  bits: 287.6 E(85289): 6.2e-77
Smith-Waterman score: 3335; 100.0% identity (100.0% similar) in 504 aa overlap (55-558:1-504)

           30        40        50        60        70        80    
pF1KB8 KPSVFGNDSDDDDETSVSESLQREAAKKQAMKQTKLEIQKALAEDATVYEYDSIYDEMQK
                                     ::::::::::::::::::::::::::::::
XP_016                               MKQTKLEIQKALAEDATVYEYDSIYDEMQK
                                             10        20        30

           90       100       110       120       130       140    
pF1KB8 KKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFV
               40        50        60        70        80        90

          150       160       170       180       190       200    
pF1KB8 TSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFRE
              100       110       120       130       140       150

          210       220       230       240       250       260    
pF1KB8 ARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETR
              160       170       180       190       200       210

          270       280       290       300       310       320    
pF1KB8 VNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQ
              220       230       240       250       260       270

          330       340       350       360       370       380    
pF1KB8 SRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDR
              280       290       300       310       320       330

          390       400       410       420       430       440    
pF1KB8 EKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGV
              340       350       360       370       380       390

          450       460       470       480       490       500    
pF1KB8 QSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTE
              400       410       420       430       440       450

          510       520       530       540       550        
pF1KB8 EGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD
              460       470       480       490       500    

>>XP_016880702 (OMIM: 616173) PREDICTED: nuclear speckle  (504 aa)
 initn: 3335 init1: 3335 opt: 3335  Z-score: 1502.3  bits: 287.6 E(85289): 6.2e-77
Smith-Waterman score: 3335; 100.0% identity (100.0% similar) in 504 aa overlap (55-558:1-504)

           30        40        50        60        70        80    
pF1KB8 KPSVFGNDSDDDDETSVSESLQREAAKKQAMKQTKLEIQKALAEDATVYEYDSIYDEMQK
                                     ::::::::::::::::::::::::::::::
XP_016                               MKQTKLEIQKALAEDATVYEYDSIYDEMQK
                                             10        20        30

           90       100       110       120       130       140    
pF1KB8 KKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFV
               40        50        60        70        80        90

          150       160       170       180       190       200    
pF1KB8 TSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFRE
              100       110       120       130       140       150

          210       220       230       240       250       260    
pF1KB8 ARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETR
              160       170       180       190       200       210

          270       280       290       300       310       320    
pF1KB8 VNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQ
              220       230       240       250       260       270

          330       340       350       360       370       380    
pF1KB8 SRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDR
              280       290       300       310       320       330

          390       400       410       420       430       440    
pF1KB8 EKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGV
              340       350       360       370       380       390

          450       460       470       480       490       500    
pF1KB8 QSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTE
              400       410       420       430       440       450

          510       520       530       540       550        
pF1KB8 EGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD
              460       470       480       490       500    

>>XP_016880701 (OMIM: 616173) PREDICTED: nuclear speckle  (504 aa)
 initn: 3335 init1: 3335 opt: 3335  Z-score: 1502.3  bits: 287.6 E(85289): 6.2e-77
Smith-Waterman score: 3335; 100.0% identity (100.0% similar) in 504 aa overlap (55-558:1-504)

           30        40        50        60        70        80    
pF1KB8 KPSVFGNDSDDDDETSVSESLQREAAKKQAMKQTKLEIQKALAEDATVYEYDSIYDEMQK
                                     ::::::::::::::::::::::::::::::
XP_016                               MKQTKLEIQKALAEDATVYEYDSIYDEMQK
                                             10        20        30

           90       100       110       120       130       140    
pF1KB8 KKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFV
               40        50        60        70        80        90

          150       160       170       180       190       200    
pF1KB8 TSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFRE
              100       110       120       130       140       150

          210       220       230       240       250       260    
pF1KB8 ARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETR
              160       170       180       190       200       210

          270       280       290       300       310       320    
pF1KB8 VNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQ
              220       230       240       250       260       270

          330       340       350       360       370       380    
pF1KB8 SRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDR
              280       290       300       310       320       330

          390       400       410       420       430       440    
pF1KB8 EKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGV
              340       350       360       370       380       390

          450       460       470       480       490       500    
pF1KB8 QSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTE
              400       410       420       430       440       450

          510       520       530       540       550        
pF1KB8 EGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD
              460       470       480       490       500    

>>XP_016880704 (OMIM: 616173) PREDICTED: nuclear speckle  (504 aa)
 initn: 3335 init1: 3335 opt: 3335  Z-score: 1502.3  bits: 287.6 E(85289): 6.2e-77
Smith-Waterman score: 3335; 100.0% identity (100.0% similar) in 504 aa overlap (55-558:1-504)

           30        40        50        60        70        80    
pF1KB8 KPSVFGNDSDDDDETSVSESLQREAAKKQAMKQTKLEIQKALAEDATVYEYDSIYDEMQK
                                     ::::::::::::::::::::::::::::::
XP_016                               MKQTKLEIQKALAEDATVYEYDSIYDEMQK
                                             10        20        30

           90       100       110       120       130       140    
pF1KB8 KKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFV
               40        50        60        70        80        90

          150       160       170       180       190       200    
pF1KB8 TSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFRE
              100       110       120       130       140       150

          210       220       230       240       250       260    
pF1KB8 ARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETR
              160       170       180       190       200       210

          270       280       290       300       310       320    
pF1KB8 VNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQ
              220       230       240       250       260       270

          330       340       350       360       370       380    
pF1KB8 SRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDR
              280       290       300       310       320       330

          390       400       410       420       430       440    
pF1KB8 EKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGV
              340       350       360       370       380       390

          450       460       470       480       490       500    
pF1KB8 QSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTE
              400       410       420       430       440       450

          510       520       530       540       550        
pF1KB8 EGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD
              460       470       480       490       500    

>>XP_016880703 (OMIM: 616173) PREDICTED: nuclear speckle  (504 aa)
 initn: 3335 init1: 3335 opt: 3335  Z-score: 1502.3  bits: 287.6 E(85289): 6.2e-77
Smith-Waterman score: 3335; 100.0% identity (100.0% similar) in 504 aa overlap (55-558:1-504)

           30        40        50        60        70        80    
pF1KB8 KPSVFGNDSDDDDETSVSESLQREAAKKQAMKQTKLEIQKALAEDATVYEYDSIYDEMQK
                                     ::::::::::::::::::::::::::::::
XP_016                               MKQTKLEIQKALAEDATVYEYDSIYDEMQK
                                             10        20        30

           90       100       110       120       130       140    
pF1KB8 KKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFV
               40        50        60        70        80        90

          150       160       170       180       190       200    
pF1KB8 TSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFRE
              100       110       120       130       140       150

          210       220       230       240       250       260    
pF1KB8 ARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETR
              160       170       180       190       200       210

          270       280       290       300       310       320    
pF1KB8 VNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQ
              220       230       240       250       260       270

          330       340       350       360       370       380    
pF1KB8 SRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDR
              280       290       300       310       320       330

          390       400       410       420       430       440    
pF1KB8 EKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGV
              340       350       360       370       380       390

          450       460       470       480       490       500    
pF1KB8 QSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTE
              400       410       420       430       440       450

          510       520       530       540       550        
pF1KB8 EGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD
              460       470       480       490       500    

>>NP_001248396 (OMIM: 616173) nuclear speckle splicing r  (504 aa)
 initn: 3335 init1: 3335 opt: 3335  Z-score: 1502.3  bits: 287.6 E(85289): 6.2e-77
Smith-Waterman score: 3335; 100.0% identity (100.0% similar) in 504 aa overlap (55-558:1-504)

           30        40        50        60        70        80    
pF1KB8 KPSVFGNDSDDDDETSVSESLQREAAKKQAMKQTKLEIQKALAEDATVYEYDSIYDEMQK
                                     ::::::::::::::::::::::::::::::
NP_001                               MKQTKLEIQKALAEDATVYEYDSIYDEMQK
                                             10        20        30

           90       100       110       120       130       140    
pF1KB8 KKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFV
               40        50        60        70        80        90

          150       160       170       180       190       200    
pF1KB8 TSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFRE
              100       110       120       130       140       150

          210       220       230       240       250       260    
pF1KB8 ARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETR
              160       170       180       190       200       210

          270       280       290       300       310       320    
pF1KB8 VNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQ
              220       230       240       250       260       270

          330       340       350       360       370       380    
pF1KB8 SRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDR
              280       290       300       310       320       330

          390       400       410       420       430       440    
pF1KB8 EKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGV
              340       350       360       370       380       390

          450       460       470       480       490       500    
pF1KB8 QSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTE
              400       410       420       430       440       450

          510       520       530       540       550        
pF1KB8 EGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD
              460       470       480       490       500    




558 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 14:20:45 2016 done: Fri Nov  4 14:20:46 2016
 Total Scan time: 11.610 Total Display time:  0.120

Function used was FASTA [36.3.4 Apr, 2011]
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