FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8664, 409 aa 1>>>pF1KB8664 409 - 409 aa - 409 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4112+/-0.000824; mu= 12.4699+/- 0.050 mean_var=94.9520+/-18.939, 0's: 0 Z-trim(109.9): 54 B-trim: 0 in 0/51 Lambda= 0.131620 statistics sampled from 11191 (11238) to 11191 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.345), width: 16 Scan time: 2.720 The best scores are: opt bits E(32554) CCDS6331.1 DEPTOR gene_id:64798|Hs108|chr8 ( 409) 2707 524.1 9.5e-149 CCDS64960.1 DEPTOR gene_id:64798|Hs108|chr8 ( 308) 1772 346.4 2.1e-95 CCDS6201.1 PREX2 gene_id:80243|Hs108|chr8 (1606) 522 109.5 2.4e-23 CCDS13410.1 PREX1 gene_id:57580|Hs108|chr20 (1659) 504 106.0 2.6e-22 >>CCDS6331.1 DEPTOR gene_id:64798|Hs108|chr8 (409 aa) initn: 2707 init1: 2707 opt: 2707 Z-score: 2784.0 bits: 524.1 E(32554): 9.5e-149 Smith-Waterman score: 2707; 99.5% identity (99.8% similar) in 409 aa overlap (1-409:1-409) 10 20 30 40 50 60 pF1KB8 MEEGGSTGSAGSDSSTSGSGGAQQRELERMAEVLVTGEQLRLRLHEEKVIKDRRHHLKTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MEEGGSTGSAGSDSSTSGSGGAQQRELERMAEVLVTGEQLRLRLHEEKVIKDRRHHLKTY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PNCFVAKELIDWLIEHKEASDRETAIKLMQKLADRGIIHHVCDEHKEFKDVKLFYRFRKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 PNCFVAKELIDWLIEHKEASDRETAIKLMQKLADRGIIHHVCDEHKEFKDVKLFYRFRKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DGTFPLDNEVKAFMRGQRLYEKLMSPENTLLQPREEEGVKYERTFMASEFLDWLVQEGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 DGTFPLDNEVKAFMRGQRLYEKLMSPENTLLQPREEEGVKYERTFMASEFLDWLVQEGEA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TTRKEAEQLCHRLMEHGIIQHVSSKHPFVDSNLLYQFRMNFRRRRRLMELLNEKSPSSQE :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: CCDS63 TTRKEAEQLCHRLMEHGIIQHVSNKHPFVDSNLLYQFRMNFRRRRRLMELLNEKSPSSQE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 THDSPFCLGKQSHDNRKSTSFMSVSPSKEIKIVSAVRRSSMSSCGSSGYFSSSPTLSSSP :::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 THDSPFCLRKQSHDNRKSTSFMSVSPSKEIKIVSAVRRSSMSSCGSSGYFSSSPTLSSSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 PVLCNPKSVLKRPVTSEELLTPGAPYARKTFTIVGDAVGWGFVVRGSKPCHIQAVDPSGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 PVLCNPKSVLKRPVTSEELLTPGAPYARKTFTIVGDAVGWGFVVRGSKPCHIQAVDPSGP 310 320 330 340 350 360 370 380 390 400 pF1KB8 AAAAGMKVCQFVVSVNGLNVLHVDYRTVSNLILTGPRTIVMEVMEELEC ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 AAAAGMKVCQFVVSVNGLNVLHVDYRTVSNLILTGPRTIVMEVMEELEC 370 380 390 400 >>CCDS64960.1 DEPTOR gene_id:64798|Hs108|chr8 (308 aa) initn: 1764 init1: 1764 opt: 1772 Z-score: 1826.3 bits: 346.4 E(32554): 2.1e-95 Smith-Waterman score: 1803; 74.8% identity (75.1% similar) in 409 aa overlap (1-409:1-308) 10 20 30 40 50 60 pF1KB8 MEEGGSTGSAGSDSSTSGSGGAQQRELERMAEVLVTGEQLRLRLHEEKVIKDRRHHLKTY :::::::::::::::::::::::::::::::::::::::::: CCDS64 MEEGGSTGSAGSDSSTSGSGGAQQRELERMAEVLVTGEQLRL------------------ 10 20 30 40 70 80 90 100 110 120 pF1KB8 PNCFVAKELIDWLIEHKEASDRETAIKLMQKLADRGIIHHVCDEHKEFKDVKLFYRFRKD CCDS64 ------------------------------------------------------------ 130 140 150 160 170 180 pF1KB8 DGTFPLDNEVKAFMRGQRLYEKLMSPENTLLQPREEEGVKYERTFMASEFLDWLVQEGEA ::::::::::::::::::::::::::::::::::::: CCDS64 -----------------------MSPENTLLQPREEEGVKYERTFMASEFLDWLVQEGEA 50 60 70 190 200 210 220 230 240 pF1KB8 TTRKEAEQLCHRLMEHGIIQHVSSKHPFVDSNLLYQFRMNFRRRRRLMELLNEKSPSSQE :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: CCDS64 TTRKEAEQLCHRLMEHGIIQHVSNKHPFVDSNLLYQFRMNFRRRRRLMELLNEKSPSSQE 80 90 100 110 120 130 250 260 270 280 290 300 pF1KB8 THDSPFCLGKQSHDNRKSTSFMSVSPSKEIKIVSAVRRSSMSSCGSSGYFSSSPTLSSSP :::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 THDSPFCLRKQSHDNRKSTSFMSVSPSKEIKIVSAVRRSSMSSCGSSGYFSSSPTLSSSP 140 150 160 170 180 190 310 320 330 340 350 360 pF1KB8 PVLCNPKSVLKRPVTSEELLTPGAPYARKTFTIVGDAVGWGFVVRGSKPCHIQAVDPSGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 PVLCNPKSVLKRPVTSEELLTPGAPYARKTFTIVGDAVGWGFVVRGSKPCHIQAVDPSGP 200 210 220 230 240 250 370 380 390 400 pF1KB8 AAAAGMKVCQFVVSVNGLNVLHVDYRTVSNLILTGPRTIVMEVMEELEC ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 AAAAGMKVCQFVVSVNGLNVLHVDYRTVSNLILTGPRTIVMEVMEELEC 260 270 280 290 300 >>CCDS6201.1 PREX2 gene_id:80243|Hs108|chr8 (1606 aa) initn: 470 init1: 355 opt: 522 Z-score: 532.6 bits: 109.5 E(32554): 2.4e-23 Smith-Waterman score: 522; 32.0% identity (61.0% similar) in 372 aa overlap (27-380:370-727) 10 20 30 40 50 pF1KB8 MEEGGSTGSAGSDSSTSGSGGAQQRELERMAEVLVT--GEQL-RLRLHEEKVIKDR .:. . :... ::.: .. .. ..:::: CCDS62 VCMAKTPEEKHEWFEAILKERERRKGLKLGMEQDTWVMISEQGEKLYKMMCRQGNLIKDR 340 350 360 370 380 390 60 70 80 90 100 110 pF1KB8 RHHLKTYPNCFVAKELIDWLIEHKEASDRETAIKLMQKLADRGIIHHVCDEHKEFKDVKL ...: :.:.::...:...::.: : : ...: : : . :::::: :.:. :: .. CCDS62 KRKLTTFPKCFLGSEFVSWLLEIGEIHRPEEGVHLGQALLENGIIHHVTDKHQ-FKPEQM 400 410 420 430 440 450 120 130 140 150 160 170 pF1KB8 FYRFRKDDGTFPLDNEVKAFM-RGQRLYEKLMSPENTLLQPREEEGVKYERTFMASEFLD .:::: ::::: ::.. . .: ::: .: : . ... .. . :. . ::....: CCDS62 LYRFRYDDGTFYPRNEMQDVISKGVRLYCRLHSLFTPVIRDKDYHLRTYKSVVMANKLID 460 470 480 490 500 510 180 190 200 210 220 230 pF1KB8 WLVQEGEATTRKEAEQLCHRLMEHGIIQHVSSKHPFVDSNLLYQFRMNFRRRRRLMELLN ::. .:. ::.:: . : ..:...:: : : : ::..: : .. :: : CCDS62 WLIAQGDCRTREEAMIFGVGLCDNGFMHHVLEKSEFKDEPLLFRF---FSDEE--MEGSN 520 530 540 550 560 570 240 250 260 270 280 pF1KB8 EKSPSSQETHDSPFC---LGKQS--HDNRKSTSFMSVSPSKEIKIVSAVRRSSMSSCGS- : :: ..:. ..:. : .: .. .... :.. :...: . .. CCDS62 MK--HRLMKHDLKVVENVIAKSLLIKSNEGSYGF-GLEDKNKVPIIKLVEKGSNAEMAGM 580 590 600 610 620 630 290 300 310 320 330 pF1KB8 ---SGYFSSSPTLSSSPP---VLCNPKSVL--KRPVTSEELLTPGAPYARKTFTIVGDAV . :. . : : : : :: : ..:. ..:. : :.: : .: CCDS62 EVGKKIFAINGDLVFMRPFNEVDCFLKSCLNSRKPL---RVLVSTKP--RETVKIPDSAD 640 650 660 670 680 340 350 360 370 380 390 pF1KB8 GWGFVVRGSKPCHIQAVDPSGPAAAAGMKVCQFVVSVNGLNVLHVDYRTVSNLILTGPRT : :: .:: : ..:: . :::::.. : ...:::.:: CCDS62 GLGFQIRGFGPSVVHAVGRGTVAAAAGLHPGQCIIKVNGINVSKETHASVIAHVTACRKY 690 700 710 720 730 740 400 pF1KB8 IVMEVMEELEC CCDS62 RRPTKQDSIQWVYNSIESAQEDLQKSHSKPPGDEAGDAFDCKVEEVIDKFNTMAIIDGKK 750 760 770 780 790 800 >>CCDS13410.1 PREX1 gene_id:57580|Hs108|chr20 (1659 aa) initn: 402 init1: 323 opt: 504 Z-score: 513.9 bits: 106.0 E(32554): 2.6e-22 Smith-Waterman score: 506; 30.1% identity (60.9% similar) in 379 aa overlap (23-382:392-761) 10 20 30 40 pF1KB8 MEEGGSTGSAGSDSSTSGSGGAQQRE-----LERMAEVLVT--GEQLRLRLH .::: .:: : :... ::.: . CCDS13 HNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKLGMERDAYVMIAEKGEKLYHMMM 370 380 390 400 410 420 50 60 70 80 90 100 pF1KB8 EEKV--IKDRRHHLKTYPNCFVAKELIDWLIEHKEASDRETAIKLMQKLADRGIIHHVCD ..:: :::::..:.: :.::...:.. ::.: : : : ...: : : . :::::: : CCDS13 NKKVNLIKDRRRKLSTVPKCFLGNEFVAWLLEIGEISKTEEGVNLGQALLENGIIHHVSD 430 440 450 460 470 480 110 120 130 140 150 160 pF1KB8 EHKEFKDVKLFYRFRKDDGTFPLDNEVKAFM-RGQRLYEKLMSPENTLLQPREEEGVKYE .:. ::. ...:::: ::::. .:.. .: .: ::: .: : . ... :. . :. CCDS13 KHQ-FKNEQVMYRFRYDDGTYKARSELEDIMSKGVRLYCRLHSLYTPVIKDRDYHLKTYK 490 500 510 520 530 540 170 180 190 200 210 220 pF1KB8 RTFMASEFLDWLVQEGEATTRKEAEQLCHRLMEHGIIQHVSSKHPFVDSNLLYQFRMNFR .. .:...:::. .:. ::.:: : : ..:...:: : : : . ..:. . CCDS13 SVLPGSKLVDWLLAQGDCQTREEAVALGVGLCNNGFMHHVLEKSEFRDESQYFRFHAD-- 550 560 570 580 590 230 240 250 260 270 pF1KB8 RRRRLMELLNEKSPSSQETHDSPFC---LGKQSHDNRKSTSF-MSVSPSKEIKIVSAVRR :. . .: ..: .: . :.:. . .. ... ... .:..:.: CCDS13 -----EEMEGTSSKNKQLRNDFKLVENILAKRLLILPQEEDYGFDIEEKNKAVVVKSVQR 600 610 620 630 640 650 280 290 300 310 320 330 pF1KB8 SSMSSCGS----SGYFSSSPTLSSSPPVLCNPKSVLKRPVTSEE-LLTPGAPYARKTFTI .:.. .. .: . : : . . .:.:.. :.. : : :.. . : CCDS13 GSLAEVAGLQVGRKIYSINEDLVFLRP-FSEVESILNQSFCSRRPLRLLVATKAKEIIKI 660 670 680 690 700 710 340 350 360 370 380 390 pF1KB8 VGDAVGWGFVVRGSKPCHIQAVDPSGPAAAAGMKVCQFVVSVNGLNVLHVDYRTVSNLIL . : .::. : .. :: .. : :::. . : ...::: ::.. CCDS13 PDQPDTLCFQIRGAAPPYVYAVGRGSEAMAAGLCAGQCILKVNGSNVMNDGAPEVLEHFQ 720 730 740 750 760 770 400 pF1KB8 TGPRTIVMEVMEELEC CCDS13 AFRSRREEALGLYQWIYHTHEDAQEARASQEASTEDPSGEQAQEEDQADSAFPLLSLGPR 780 790 800 810 820 830 409 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 19:43:48 2016 done: Fri Nov 4 19:43:49 2016 Total Scan time: 2.720 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]