FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8665, 499 aa
  1>>>pF1KB8665 499 - 499 aa - 499 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.9238+/-0.000828; mu= 16.4532+/- 0.050
 mean_var=88.6368+/-17.360, 0's: 0 Z-trim(108.3): 22  B-trim: 0 in 0/52
 Lambda= 0.136228
 statistics sampled from 10128 (10139) to 10128 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.311), width:  16
 Scan time:  3.280

The best scores are:                                      opt bits E(32554)
CCDS12879.1 PRPF31 gene_id:26121|Hs108|chr19       ( 499) 3156 630.2 1.5e-180
CCDS2353.1 NOP58 gene_id:51602|Hs108|chr2          ( 529)  427 93.9 4.6e-19
CCDS13030.1 NOP56 gene_id:10528|Hs108|chr20        ( 594)  399 88.4 2.3e-17


>>CCDS12879.1 PRPF31 gene_id:26121|Hs108|chr19            (499 aa)
 initn: 3156 init1: 3156 opt: 3156  Z-score: 3354.7  bits: 630.2 E(32554): 1.5e-180
Smith-Waterman score: 3156; 99.8% identity (100.0% similar) in 499 aa overlap (1-499:1-499)

               10        20        30        40        50        60
pF1KB8 MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 AEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 AEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 RFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 EEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 EEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LSKVPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCT
       :::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 LSKMPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 LAARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 LAARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 KMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 KMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF
              430       440       450       460       470       480

              490         
pF1KB8 SSMAEFLKVKGEKSGLMST
       :::::::::::::::::::
CCDS12 SSMAEFLKVKGEKSGLMST
              490         

>>CCDS2353.1 NOP58 gene_id:51602|Hs108|chr2               (529 aa)
 initn: 402 init1: 324 opt: 427  Z-score: 455.7  bits: 93.9 E(32554): 4.6e-19
Smith-Waterman score: 437; 23.6% identity (61.2% similar) in 381 aa overlap (92-471:161-521)

              70        80        90       100       110       120 
pF1KB8 EIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKR
                                     .::.: .:  ....:::      :. :. .
CCDS23 EPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWH
              140       150       160       170       180       190

             130       140       150       160       170       180 
pF1KB8 FPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLSE
       :::: ... . : : . ....:.   :   . .:...: . .   :...:  ..: ..::
CCDS23 FPELGKIISDNLTYCKCLQKVGDR--KNYASAKLSELLPEEVEAEVKAAAEISMGTEVSE
              200       210         220       230       240        

             190       200       210       220       230       240 
pF1KB8 EELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTNL
       :..  . . : ...:..  . ..:::...::  ::::.....:  ..:.... ::.: ::
CCDS23 EDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNL
      250       260       270       280       290       300        

             250       260       270       280       290       300 
pF1KB8 SKVPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCTL
       .:  : ....:::..  . ...:    :. : :::...: .  :  . : .:..::: .:
CCDS23 AKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQTSPKHKGKISRMLAAKTVL
      310       320       330       340       350       360        

             310       320       330       340       350       360 
pF1KB8 AARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYRK
       : : :.: :.. . .: : . ..: .. .  :   .....     : .. .:   .   :
CCDS23 AIRYDAFGEDSSSAMGVENRAKLEARL-RTLEDRGIRKISGTGKAL-AKTEKYEHKSEVK
      370       380       390        400       410        420      

             370       380        390       400       410       420
pF1KB8 MKERLGLTEIRKQANRMSFGEIE-EDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI
         .  : . .   ... .. ... ::   :          :. ..... ..:.:  . ..
CCDS23 TYDPSGDSTLPTCSKKRKIEQVDKEDEITEK---------KAKKAKIK-VKVEEEEEEKV
        430       440       450                460        470      

              430       440       450       460       470       480
pF1KB8 SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF
       ..  . ...:..   : :. :...  .        :  .  :..:.  .::         
CCDS23 AEEEETSVKKKKK-RGKKKHIKEEPLSEEE-----PCTSTAIASPEKKKKKKKKRENED 
        480        490       500            510       520          

              490         
pF1KB8 SSMAEFLKVKGEKSGLMST

>>CCDS13030.1 NOP56 gene_id:10528|Hs108|chr20             (594 aa)
 initn: 388 init1: 295 opt: 399  Z-score: 425.2  bits: 88.4 E(32554): 2.3e-17
Smith-Waterman score: 410; 24.7% identity (63.0% similar) in 308 aa overlap (92-386:167-474)

              70        80        90       100       110       120 
pF1KB8 EIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKR
                                     .:... .:  ......: .   .:. :. .
CCDS13 TDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYH
        140       150       160       170       180       190      

             130       140       150        160       170          
pF1KB8 FPELESLVPNALDYIRTVKELGNSLDKCKNN-ENLQQILTNATIMVVSVTAS-TTQGQQL
       :::: ... .   : : .. .::  .  ... :.:...  ...   . . :: ...:...
CCDS13 FPELVKIINDNATYCRLAQFIGNRRELNEDKLEKLEELTMDGAKAKAILDASRSSMGMDI
        200       210       220       230       240       250      

     180       190       200       210       220       230         
pF1KB8 SEEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLT
       :  .:  .:   . .. :.  .. .. :..:.:: .::.:: .:: ...:.... ::.::
CCDS13 SAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLT
        260       270       280       290       300       310      

     240       250       260       270       280       290         
pF1KB8 NLSKVPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKC
       ::.: :: ....:::..  . .... .  :. : :.:: ..       . . .: .: ::
CCDS13 NLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKC
        320       330       340       350       360       370      

     300       310       320       330                  340        
pF1KB8 TLAARVDSFHESTEGKVGYELKDEIERKFDKWQ--EPP---------PVKQVKPLPAPLD
       ..:.:.: : :   .  : .:....:.... ..  : :          . :..   : . 
CCDS13 SIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEIT
        380       390       400       410       420       430      

      350       360       370       380       390       400        
pF1KB8 GQRKKRGGRRYRKMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVR
        . .:.  .: .: :.::.   . .. :  :  :  :.                      
CCDS13 RKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGM
        440       450       460       470       480       490      

      410       420       430       440       450       460        
pF1KB8 QTQVNEATKARISKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAA
                                                                   
CCDS13 EDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGS
        500       510       520       530       540       550      




499 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 14:21:20 2016 done: Fri Nov  4 14:21:20 2016
 Total Scan time:  3.280 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]