FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8667, 424 aa 1>>>pF1KB8667 424 - 424 aa - 424 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3241+/-0.000374; mu= 17.3700+/- 0.023 mean_var=68.7391+/-14.299, 0's: 0 Z-trim(113.0): 12 B-trim: 721 in 1/54 Lambda= 0.154694 statistics sampled from 22070 (22082) to 22070 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.259), width: 16 Scan time: 7.580 The best scores are: opt bits E(85289) NP_061913 (OMIM: 106210,606985,617141) elongator c ( 424) 2791 632.1 8.3e-181 NP_001275655 (OMIM: 106210,606985,617141) elongato ( 535) 2496 566.3 6.6e-161 NP_001275654 (OMIM: 106210,606985,617141) elongato ( 476) 2484 563.6 3.8e-160 >>NP_061913 (OMIM: 106210,606985,617141) elongator compl (424 aa) initn: 2791 init1: 2791 opt: 2791 Z-score: 3367.1 bits: 632.1 E(85289): 8.3e-181 Smith-Waterman score: 2791; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424) 10 20 30 40 50 60 pF1KB8 MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LLVSTGLPALDQLLGGGLAVGTVLLIEEDKYNIYSPLLFKYFLAEGIVNGHTLLVASAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 LLVSTGLPALDQLLGGGLAVGTVLLIEEDKYNIYSPLLFKYFLAEGIVNGHTLLVASAKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 DPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 GHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 DGSNPQKKQRNILRIGIQNLGSPLWGDDICCAENGGNSHSLTKFLYVLRGLLRTSLSACI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 DGSNPQKKQRNILRIGIQNLGSPLWGDDICCAENGGNSHSLTKFLYVLRGLLRTSLSACI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 ITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 CDESDVKDLAFKLKRKLFTIERLHLPPDLSDTVSRSSKMDLAESAKRLGPGCGMMAGGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 CDESDVKDLAFKLKRKLFTIERLHLPPDLSDTVSRSSKMDLAESAKRLGPGCGMMAGGKK 370 380 390 400 410 420 pF1KB8 HLDF :::: NP_061 HLDF >>NP_001275655 (OMIM: 106210,606985,617141) elongator co (535 aa) initn: 2496 init1: 2496 opt: 2496 Z-score: 3009.8 bits: 566.3 E(85289): 6.6e-161 Smith-Waterman score: 2496; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:1-381) 10 20 30 40 50 60 pF1KB8 MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LLVSTGLPALDQLLGGGLAVGTVLLIEEDKYNIYSPLLFKYFLAEGIVNGHTLLVASAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLVSTGLPALDQLLGGGLAVGTVLLIEEDKYNIYSPLLFKYFLAEGIVNGHTLLVASAKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 DGSNPQKKQRNILRIGIQNLGSPLWGDDICCAENGGNSHSLTKFLYVLRGLLRTSLSACI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGSNPQKKQRNILRIGIQNLGSPLWGDDICCAENGGNSHSLTKFLYVLRGLLRTSLSACI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 CDESDVKDLAFKLKRKLFTIERLHLPPDLSDTVSRSSKMDLAESAKRLGPGCGMMAGGKK ::::::::::::::::::::: NP_001 CDESDVKDLAFKLKRKLFTIEAGVQWHDLGSRQPRLLGSSNSPASASLVAGITGAHHHTQ 370 380 390 400 410 420 >>NP_001275654 (OMIM: 106210,606985,617141) elongator co (476 aa) initn: 1401 init1: 1401 opt: 2484 Z-score: 2996.0 bits: 563.6 E(85289): 3.8e-160 Smith-Waterman score: 2484; 99.7% identity (99.7% similar) in 382 aa overlap (1-381:1-382) 10 20 30 40 50 60 pF1KB8 MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LLVSTGLPALDQLLGGGLAVGTVLLIEEDKYNIYSPLLFKYFLAEGIVNGHTLLVASAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLVSTGLPALDQLLGGGLAVGTVLLIEEDKYNIYSPLLFKYFLAEGIVNGHTLLVASAKE 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 DPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKME-IGPVSSSR ::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: NP_001 DPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEQIGPVSSSR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 FGHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 FDGSNPQKKQRNILRIGIQNLGSPLWGDDICCAENGGNSHSLTKFLYVLRGLLRTSLSAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FDGSNPQKKQRNILRIGIQNLGSPLWGDDICCAENGGNSHSLTKFLYVLRGLLRTSLSAC 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 IITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 ICDESDVKDLAFKLKRKLFTIERLHLPPDLSDTVSRSSKMDLAESAKRLGPGCGMMAGGK :::::::::::::::::::::: NP_001 ICDESDVKDLAFKLKRKLFTIEWVQDNYLRQERNIYPPGFSYLLKQKDSAWGEGSLQHST 370 380 390 400 410 420 424 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:22:30 2016 done: Fri Nov 4 14:22:31 2016 Total Scan time: 7.580 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]