FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8668, 463 aa 1>>>pF1KB8668 463 - 463 aa - 463 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7459+/-0.000846; mu= 14.9077+/- 0.051 mean_var=62.5924+/-12.489, 0's: 0 Z-trim(106.1): 28 B-trim: 419 in 1/52 Lambda= 0.162111 statistics sampled from 8772 (8794) to 8772 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.27), width: 16 Scan time: 2.400 The best scores are: opt bits E(32554) CCDS2909.1 UBA3 gene_id:9039|Hs108|chr3 ( 463) 3097 733.0 1.5e-211 CCDS2910.1 UBA3 gene_id:9039|Hs108|chr3 ( 449) 2969 703.1 1.5e-202 CCDS12439.1 UBA2 gene_id:10054|Hs108|chr19 ( 640) 380 97.6 4e-20 CCDS2805.1 UBA7 gene_id:7318|Hs108|chr3 (1012) 364 93.9 8.2e-19 CCDS3516.1 UBA6 gene_id:55236|Hs108|chr4 (1052) 306 80.3 1e-14 >>CCDS2909.1 UBA3 gene_id:9039|Hs108|chr3 (463 aa) initn: 3097 init1: 3097 opt: 3097 Z-score: 3911.3 bits: 733.0 E(32554): 1.5e-211 Smith-Waterman score: 3097; 99.6% identity (99.6% similar) in 463 aa overlap (1-463:1-463) 10 20 30 40 50 60 pF1KB8 MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 ESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GRPKAEVAAEFLNDRVPNCNVVPHFYKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLI ::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::: CCDS29 GRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 SLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SMPRLPEHCIEYVRMLQWPKEQPFGEGVPLGGDDPEHIQWIFQKSLERASQYNIRGVTYR :::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: CCDS29 SMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 LTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAER 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 KENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYLQSVTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 KENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYLQSVTS 370 380 390 400 410 420 430 440 450 460 pF1KB8 IEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS ::::::::::::::::::::::::::::::::::::::::::: CCDS29 IEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS 430 440 450 460 >>CCDS2910.1 UBA3 gene_id:9039|Hs108|chr3 (449 aa) initn: 2969 init1: 2969 opt: 2969 Z-score: 3749.8 bits: 703.1 E(32554): 1.5e-202 Smith-Waterman score: 2976; 96.5% identity (96.5% similar) in 463 aa overlap (1-463:1-449) 10 20 30 40 50 60 pF1KB8 MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPST ::::::: ::::::::::::::::::::::::::::::::::::::: CCDS29 MADGEEP--------------MAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPST 10 20 30 40 70 80 90 100 110 120 pF1KB8 ESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 ESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDI 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 GRPKAEVAAEFLNDRVPNCNVVPHFYKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLI ::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::: CCDS29 GRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLI 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 SLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 SLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIA 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 SMPRLPEHCIEYVRMLQWPKEQPFGEGVPLGGDDPEHIQWIFQKSLERASQYNIRGVTYR :::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: CCDS29 SMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYR 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 LTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 LTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAER 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB8 KENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYLQSVTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 KENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYLQSVTS 350 360 370 380 390 400 430 440 450 460 pF1KB8 IEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS ::::::::::::::::::::::::::::::::::::::::::: CCDS29 IEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS 410 420 430 440 >>CCDS12439.1 UBA2 gene_id:10054|Hs108|chr19 (640 aa) initn: 581 init1: 290 opt: 380 Z-score: 474.7 bits: 97.6 E(32554): 4e-20 Smith-Waterman score: 534; 41.9% identity (62.3% similar) in 236 aa overlap (71-302:19-239) 50 60 70 80 90 100 pF1KB8 VKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVID .:::.::::.::::::::.:.:: .: .:: CCDS12 MALSRGLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLID 10 20 30 40 110 120 130 140 150 pF1KB8 MDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFYKIQ--DFNDTFYRQ .::::::::::::::. : .:: ::.:: : . . :. :.: . .:. :.: :.:: CCDS12 LDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIVAYHDSIMNPDYNVEFFRQ 50 60 70 80 90 100 160 170 180 190 200 210 pF1KB8 FHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMT : ... .::. :: .: : .. : ::::..:: :. :.. .: :.: CCDS12 FILVMNALDNRAARNHVNRMCLA----AD--------VPLIESGTAGYLGQVTTIKKGVT 110 120 130 140 150 220 230 240 250 260 270 pF1KB8 ACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVRML--QWPKEQPFGEGVPLGGDDPE : :: . : : .:: ::: . : : ::: ....: : :. . : ::: CCDS12 ECYECHPK--PTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDRADPE 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB8 HIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAY : .. :: : : :.. CCDS12 -AAWEPTEAEARARASNEDGDIKRISTKEWAKSTGYDPVKLFTKLFKDDIRYLLTMDKLW 220 230 240 250 260 270 >>CCDS2805.1 UBA7 gene_id:7318|Hs108|chr3 (1012 aa) initn: 249 init1: 188 opt: 364 Z-score: 451.2 bits: 93.9 E(32554): 8.2e-19 Smith-Waterman score: 367; 33.9% identity (57.3% similar) in 218 aa overlap (73-279:436-634) 50 60 70 80 90 pF1KB8 KFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQ-----IH :..:::..:::::: .:: :. . CCDS28 EDCALRGSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLT 410 420 430 440 450 460 100 110 120 130 140 150 pF1KB8 VIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFYKIQD-----FN :.::: :. :::.:::::: .:.::::::::: :. .:.: : .. .. CCDS28 VVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYG 470 480 490 500 510 520 160 170 180 190 200 210 pF1KB8 DTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARV :.:. . .. .:::. :::.. . :. ::...:: : :.: : CCDS28 DNFFSRVDGVAAALDSFQARRYVAARCTHYLK------------PLLEAGTSGTWGSATV 530 540 550 560 570 220 230 240 250 260 270 pF1KB8 ILPGMTACIECTLELYPPQ-VNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLG ..: .: . . . .:.::. .: :: ::: ... : : :. CCDS28 FMPHVTEAYRAPASAAASEDAPYPVCTVRYFPSTAEHT------LQWARHE-FEELFRLS 580 590 600 610 620 280 290 300 310 320 330 pF1KB8 GDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKI .. .: : CCDS28 AETINHHQQAHTSLADMDEPQTLTLLKPVLGVLRVRPQNWQDCVAWALGHWKLCFHYGIK 630 640 650 660 670 680 >>CCDS3516.1 UBA6 gene_id:55236|Hs108|chr4 (1052 aa) initn: 460 init1: 139 opt: 306 Z-score: 377.6 bits: 80.3 E(32554): 1e-14 Smith-Waterman score: 372; 34.7% identity (61.8% similar) in 199 aa overlap (67-254:458-642) 40 50 60 70 80 90 pF1KB8 RWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFR-- :.. .....: :..:::.:::.:: : CCDS35 LGKPECEEFLPRGDRYDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTS 430 440 450 460 470 480 100 110 120 130 140 150 pF1KB8 ----QIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFYKIQD .: : : : :. :::::::::::. : .::. .::. . .. :. :. CCDS35 KEKGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLKINSQIKIDAHLNKVCP 490 500 510 520 530 540 160 170 180 190 200 pF1KB8 -----FNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEG .:: :: . .:. .::.. :::.... .. : ::.:.:: : CCDS35 TTETIYNDEFYTKQDVIITALDNVEARRYVDSRCLANLR------------PLLDSGTMG 550 560 570 580 590 210 220 230 240 250 260 pF1KB8 FKGNARVILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFG ::...::.: .: . . ::. ..:.::. :.: :: :...: CCDS35 TKGHTEVIVPHLTESYNSHRD--PPEEEIPFCTLKSFPAAIEHTIQWARDKFESSFSHKP 600 610 620 630 640 650 270 280 290 300 310 320 pF1KB8 EGVPLGGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCA CCDS35 SLFNKFWQTYSSAEEVLQKIQSGHSLEGCFQVIKLLSRRPRNWSQCVELARLKFEKYFNH 660 670 680 690 700 710 463 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:23:04 2016 done: Fri Nov 4 14:23:04 2016 Total Scan time: 2.400 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]