FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8668, 463 aa
1>>>pF1KB8668 463 - 463 aa - 463 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1294+/-0.000352; mu= 18.8564+/- 0.022
mean_var=61.6793+/-12.584, 0's: 0 Z-trim(112.8): 69 B-trim: 1140 in 1/56
Lambda= 0.163307
statistics sampled from 21790 (21860) to 21790 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.256), width: 16
Scan time: 8.820
The best scores are: opt bits E(85289)
NP_003959 (OMIM: 603172) NEDD8-activating enzyme E ( 463) 3097 738.3 1e-212
NP_937838 (OMIM: 603172) NEDD8-activating enzyme E ( 449) 2969 708.1 1.2e-203
XP_011532513 (OMIM: 603172) PREDICTED: NEDD8-activ ( 422) 2482 593.4 3.9e-169
XP_011532512 (OMIM: 603172) PREDICTED: NEDD8-activ ( 436) 2482 593.4 4e-169
NP_005490 (OMIM: 613295) SUMO-activating enzyme su ( 640) 380 98.3 6.7e-20
XP_011532374 (OMIM: 191325) PREDICTED: ubiquitin-l ( 796) 364 94.5 1.1e-18
XP_005265487 (OMIM: 191325) PREDICTED: ubiquitin-l ( 987) 364 94.6 1.3e-18
NP_003326 (OMIM: 191325) ubiquitin-like modifier-a (1012) 364 94.6 1.3e-18
XP_016863848 (OMIM: 611361) PREDICTED: ubiquitin-l (1009) 306 80.9 1.7e-14
NP_060697 (OMIM: 611361) ubiquitin-like modifier-a (1052) 306 80.9 1.8e-14
XP_016881623 (OMIM: 613295) PREDICTED: SUMO-activa ( 608) 244 66.2 2.8e-10
XP_011524606 (OMIM: 613295) PREDICTED: SUMO-activa ( 700) 244 66.2 3.2e-10
XP_005258461 (OMIM: 613295) PREDICTED: SUMO-activa ( 752) 244 66.2 3.4e-10
NP_055299 (OMIM: 609277) adenylyltransferase and s ( 460) 185 52.2 3.4e-06
NP_079094 (OMIM: 610552,617132,617133) ubiquitin-l ( 404) 183 51.7 4.3e-06
NP_001139186 (OMIM: 613294) SUMO-activating enzyme ( 266) 180 50.9 4.9e-06
XP_006723028 (OMIM: 613294) PREDICTED: SUMO-activa ( 281) 180 50.9 5.1e-06
NP_001139185 (OMIM: 613294) SUMO-activating enzyme ( 299) 180 51.0 5.4e-06
NP_005491 (OMIM: 613294) SUMO-activating enzyme su ( 346) 180 51.0 6.1e-06
XP_016881624 (OMIM: 613294) PREDICTED: SUMO-activa ( 349) 180 51.0 6.2e-06
XP_006723026 (OMIM: 613294) PREDICTED: SUMO-activa ( 378) 180 51.0 6.6e-06
NP_938143 (OMIM: 610552,617132,617133) ubiquitin-l ( 348) 172 49.1 2.3e-05
NP_001307139 (OMIM: 610552,617132,617133) ubiquiti ( 348) 172 49.1 2.3e-05
XP_016885269 (OMIM: 301830,314370) PREDICTED: ubiq (1058) 165 47.7 0.00018
XP_016885270 (OMIM: 301830,314370) PREDICTED: ubiq (1058) 165 47.7 0.00018
NP_695012 (OMIM: 301830,314370) ubiquitin-like mod (1058) 165 47.7 0.00018
NP_003325 (OMIM: 301830,314370) ubiquitin-like mod (1058) 165 47.7 0.00018
XP_005272706 (OMIM: 301830,314370) PREDICTED: ubiq (1064) 165 47.7 0.00018
XP_016885268 (OMIM: 301830,314370) PREDICTED: ubiq (1064) 165 47.7 0.00018
XP_011542256 (OMIM: 301830,314370) PREDICTED: ubiq (1072) 165 47.7 0.00018
XP_016885267 (OMIM: 301830,314370) PREDICTED: ubiq (1086) 165 47.7 0.00018
XP_016885266 (OMIM: 301830,314370) PREDICTED: ubiq (1109) 165 47.7 0.00019
NP_001018169 (OMIM: 603385) NEDD8-activating enzym ( 528) 155 45.2 0.00052
NP_003896 (OMIM: 603385) NEDD8-activating enzyme E ( 534) 155 45.2 0.00052
XP_016861043 (OMIM: 608760) PREDICTED: ubiquitin-l ( 390) 149 43.7 0.0011
XP_016861042 (OMIM: 608760) PREDICTED: ubiquitin-l ( 392) 149 43.7 0.0011
NP_001138384 (OMIM: 608760) ubiquitin-like modifie ( 623) 149 43.8 0.0016
XP_016861040 (OMIM: 608760) PREDICTED: ubiquitin-l ( 672) 149 43.8 0.0017
NP_001129503 (OMIM: 608760) ubiquitin-like modifie ( 676) 149 43.8 0.0017
XP_011531588 (OMIM: 608760) PREDICTED: ubiquitin-l ( 676) 149 43.8 0.0017
XP_011531586 (OMIM: 608760) PREDICTED: ubiquitin-l ( 694) 149 43.8 0.0017
XP_011531585 (OMIM: 608760) PREDICTED: ubiquitin-l ( 699) 149 43.8 0.0017
XP_016861037 (OMIM: 608760) PREDICTED: ubiquitin-l ( 699) 149 43.8 0.0017
XP_016861036 (OMIM: 608760) PREDICTED: ubiquitin-l ( 701) 149 43.8 0.0017
XP_016861035 (OMIM: 608760) PREDICTED: ubiquitin-l ( 703) 149 43.8 0.0018
XP_016861033 (OMIM: 608760) PREDICTED: ubiquitin-l ( 703) 149 43.8 0.0018
XP_016861034 (OMIM: 608760) PREDICTED: ubiquitin-l ( 703) 149 43.8 0.0018
NP_006386 (OMIM: 608760) ubiquitin-like modifier-a ( 703) 149 43.8 0.0018
XP_011531584 (OMIM: 608760) PREDICTED: ubiquitin-l ( 703) 149 43.8 0.0018
XP_011531583 (OMIM: 608760) PREDICTED: ubiquitin-l ( 710) 149 43.9 0.0018
>>NP_003959 (OMIM: 603172) NEDD8-activating enzyme E1 ca (463 aa)
initn: 3097 init1: 3097 opt: 3097 Z-score: 3939.9 bits: 738.3 E(85289): 1e-212
Smith-Waterman score: 3097; 99.6% identity (99.6% similar) in 463 aa overlap (1-463:1-463)
10 20 30 40 50 60
pF1KB8 MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPST
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GRPKAEVAAEFLNDRVPNCNVVPHFYKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLI
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
NP_003 GRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 SLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SMPRLPEHCIEYVRMLQWPKEQPFGEGVPLGGDDPEHIQWIFQKSLERASQYNIRGVTYR
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
NP_003 SMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAER
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 KENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYLQSVTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYLQSVTS
370 380 390 400 410 420
430 440 450 460
pF1KB8 IEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS
:::::::::::::::::::::::::::::::::::::::::::
NP_003 IEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS
430 440 450 460
>>NP_937838 (OMIM: 603172) NEDD8-activating enzyme E1 ca (449 aa)
initn: 2969 init1: 2969 opt: 2969 Z-score: 3777.1 bits: 708.1 E(85289): 1.2e-203
Smith-Waterman score: 2976; 96.5% identity (96.5% similar) in 463 aa overlap (1-463:1-449)
10 20 30 40 50 60
pF1KB8 MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPST
::::::: :::::::::::::::::::::::::::::::::::::::
NP_937 MADGEEP--------------MAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPST
10 20 30 40
70 80 90 100 110 120
pF1KB8 ESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 ESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDI
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB8 GRPKAEVAAEFLNDRVPNCNVVPHFYKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLI
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
NP_937 GRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLI
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB8 SLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 SLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB8 SMPRLPEHCIEYVRMLQWPKEQPFGEGVPLGGDDPEHIQWIFQKSLERASQYNIRGVTYR
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
NP_937 SMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYR
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB8 LTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 LTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAER
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB8 KENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYLQSVTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 KENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYLQSVTS
350 360 370 380 390 400
430 440 450 460
pF1KB8 IEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS
:::::::::::::::::::::::::::::::::::::::::::
NP_937 IEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS
410 420 430 440
>>XP_011532513 (OMIM: 603172) PREDICTED: NEDD8-activatin (422 aa)
initn: 2518 init1: 2482 opt: 2482 Z-score: 3157.5 bits: 593.4 E(85289): 3.9e-169
Smith-Waterman score: 2736; 90.7% identity (90.7% similar) in 463 aa overlap (1-463:1-422)
10 20 30 40 50 60
pF1KB8 MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPST
::::::: :::::::::::::::::::::::::::::::::::::::
XP_011 MADGEEP--------------MAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPST
10 20 30 40
70 80 90 100 110 120
pF1KB8 ESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDI
: ::::::::::::::::::::::::::::::::
XP_011 E---------------------------ALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDI
50 60 70
130 140 150 160 170 180
pF1KB8 GRPKAEVAAEFLNDRVPNCNVVPHFYKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLI
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_011 GRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLI
80 90 100 110 120 130
190 200 210 220 230 240
pF1KB8 SLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIA
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB8 SMPRLPEHCIEYVRMLQWPKEQPFGEGVPLGGDDPEHIQWIFQKSLERASQYNIRGVTYR
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_011 SMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYR
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB8 LTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAER
260 270 280 290 300 310
370 380 390 400 410 420
pF1KB8 KENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYLQSVTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYLQSVTS
320 330 340 350 360 370
430 440 450 460
pF1KB8 IEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS
:::::::::::::::::::::::::::::::::::::::::::
XP_011 IEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS
380 390 400 410 420
>>XP_011532512 (OMIM: 603172) PREDICTED: NEDD8-activatin (436 aa)
initn: 2482 init1: 2482 opt: 2482 Z-score: 3157.2 bits: 593.4 E(85289): 4e-169
Smith-Waterman score: 2857; 93.7% identity (93.7% similar) in 463 aa overlap (1-463:1-436)
10 20 30 40 50 60
pF1KB8 MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPST
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDI
: ::::::::::::::::::::::::::::::::
XP_011 E---------------------------ALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDI
70 80 90
130 140 150 160 170 180
pF1KB8 GRPKAEVAAEFLNDRVPNCNVVPHFYKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLI
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_011 GRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB8 SLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB8 SMPRLPEHCIEYVRMLQWPKEQPFGEGVPLGGDDPEHIQWIFQKSLERASQYNIRGVTYR
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_011 SMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYR
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB8 LTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAER
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB8 KENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYLQSVTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYLQSVTS
340 350 360 370 380 390
430 440 450 460
pF1KB8 IEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS
:::::::::::::::::::::::::::::::::::::::::::
XP_011 IEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS
400 410 420 430
>>NP_005490 (OMIM: 613295) SUMO-activating enzyme subuni (640 aa)
initn: 581 init1: 290 opt: 380 Z-score: 478.3 bits: 98.3 E(85289): 6.7e-20
Smith-Waterman score: 534; 41.9% identity (62.3% similar) in 236 aa overlap (71-302:19-239)
50 60 70 80 90 100
pF1KB8 VKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVID
.:::.::::.::::::::.:.:: .: .::
NP_005 MALSRGLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLID
10 20 30 40
110 120 130 140 150
pF1KB8 MDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFYKIQ--DFNDTFYRQ
.::::::::::::::. : .:: ::.:: : . . :. :.: . .:. :.: :.::
NP_005 LDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIVAYHDSIMNPDYNVEFFRQ
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB8 FHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMT
: ... .::. :: .: : .. : ::::..:: :. :.. .: :.:
NP_005 FILVMNALDNRAARNHVNRMCLA----AD--------VPLIESGTAGYLGQVTTIKKGVT
110 120 130 140 150
220 230 240 250 260 270
pF1KB8 ACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVRML--QWPKEQPFGEGVPLGGDDPE
: :: . : : .:: ::: . : : ::: ....: : :. . : :::
NP_005 ECYECHPK--PTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDRADPE
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB8 HIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAY
: .. :: : : :..
NP_005 -AAWEPTEAEARARASNEDGDIKRISTKEWAKSTGYDPVKLFTKLFKDDIRYLLTMDKLW
220 230 240 250 260 270
>>XP_011532374 (OMIM: 191325) PREDICTED: ubiquitin-like (796 aa)
initn: 316 init1: 188 opt: 364 Z-score: 456.5 bits: 94.5 E(85289): 1.1e-18
Smith-Waterman score: 367; 33.9% identity (57.3% similar) in 218 aa overlap (73-279:220-418)
50 60 70 80 90
pF1KB8 KFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQ-----IH
:..:::..:::::: .:: :. .
XP_011 EDCALRGSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLT
190 200 210 220 230 240
100 110 120 130 140 150
pF1KB8 VIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFYKIQD-----FN
:.::: :. :::.:::::: .:.::::::::: :. .:.: : .. ..
XP_011 VVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYG
250 260 270 280 290 300
160 170 180 190 200 210
pF1KB8 DTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARV
:.:. . .. .:::. :::.. . :. ::...:: : :.: :
XP_011 DNFFSRVDGVAAALDSFQARRYVAARCTHYLK------------PLLEAGTSGTWGSATV
310 320 330 340 350
220 230 240 250 260 270
pF1KB8 ILPGMTACIECTLELYPPQ-VNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLG
..: .: . . . .:.::. .: :: ::: ... : : :.
XP_011 FMPHVTEAYRAPASAAASEDAPYPVCTVRYFPSTAEHT------LQWARHE-FEELFRLS
360 370 380 390 400 410
280 290 300 310 320 330
pF1KB8 GDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKI
.. .: :
XP_011 AETINHHQQAHTSLADMDEPQTLTLLKPVLGVLRVRPQNWQDCVAWALGHWKLCFHYGIK
420 430 440 450 460 470
>>XP_005265487 (OMIM: 191325) PREDICTED: ubiquitin-like (987 aa)
initn: 249 init1: 188 opt: 364 Z-score: 455.1 bits: 94.6 E(85289): 1.3e-18
Smith-Waterman score: 367; 33.9% identity (57.3% similar) in 218 aa overlap (73-279:436-634)
50 60 70 80 90
pF1KB8 KFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQ-----IH
:..:::..:::::: .:: :. .
XP_005 EDCALRGSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLT
410 420 430 440 450 460
100 110 120 130 140 150
pF1KB8 VIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFYKIQD-----FN
:.::: :. :::.:::::: .:.::::::::: :. .:.: : .. ..
XP_005 VVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYG
470 480 490 500 510 520
160 170 180 190 200 210
pF1KB8 DTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARV
:.:. . .. .:::. :::.. . :. ::...:: : :.: :
XP_005 DNFFSRVDGVAAALDSFQARRYVAARCTHYLK------------PLLEAGTSGTWGSATV
530 540 550 560 570
220 230 240 250 260 270
pF1KB8 ILPGMTACIECTLELYPPQ-VNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLG
..: .: . . . .:.::. .: :: ::: ... : : :.
XP_005 FMPHVTEAYRAPASAAASEDAPYPVCTVRYFPSTAEHT------LQWARHE-FEELFRLS
580 590 600 610 620
280 290 300 310 320 330
pF1KB8 GDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKI
.. .: :
XP_005 AETINHHQQAHTSLADMDEPQTLTLLKPVLGVLRVRPQNWQDCVAWALGHWKLCFHYGIK
630 640 650 660 670 680
>>NP_003326 (OMIM: 191325) ubiquitin-like modifier-activ (1012 aa)
initn: 249 init1: 188 opt: 364 Z-score: 454.9 bits: 94.6 E(85289): 1.3e-18
Smith-Waterman score: 367; 33.9% identity (57.3% similar) in 218 aa overlap (73-279:436-634)
50 60 70 80 90
pF1KB8 KFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQ-----IH
:..:::..:::::: .:: :. .
NP_003 EDCALRGSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLT
410 420 430 440 450 460
100 110 120 130 140 150
pF1KB8 VIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFYKIQD-----FN
:.::: :. :::.:::::: .:.::::::::: :. .:.: : .. ..
NP_003 VVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYG
470 480 490 500 510 520
160 170 180 190 200 210
pF1KB8 DTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARV
:.:. . .. .:::. :::.. . :. ::...:: : :.: :
NP_003 DNFFSRVDGVAAALDSFQARRYVAARCTHYLK------------PLLEAGTSGTWGSATV
530 540 550 560 570
220 230 240 250 260 270
pF1KB8 ILPGMTACIECTLELYPPQ-VNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLG
..: .: . . . .:.::. .: :: ::: ... : : :.
NP_003 FMPHVTEAYRAPASAAASEDAPYPVCTVRYFPSTAEHT------LQWARHE-FEELFRLS
580 590 600 610 620
280 290 300 310 320 330
pF1KB8 GDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKI
.. .: :
NP_003 AETINHHQQAHTSLADMDEPQTLTLLKPVLGVLRVRPQNWQDCVAWALGHWKLCFHYGIK
630 640 650 660 670 680
>>XP_016863848 (OMIM: 611361) PREDICTED: ubiquitin-like (1009 aa)
initn: 460 init1: 139 opt: 306 Z-score: 381.1 bits: 80.9 E(85289): 1.7e-14
Smith-Waterman score: 372; 34.7% identity (61.8% similar) in 199 aa overlap (67-254:458-642)
40 50 60 70 80 90
pF1KB8 RWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFR--
:.. .....: :..:::.:::.:: :
XP_016 LGKPECEEFLPRGDRYDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTS
430 440 450 460 470 480
100 110 120 130 140 150
pF1KB8 ----QIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFYKIQD
.: : : : :. :::::::::::. : .::. .::. . .. :. :.
XP_016 KEKGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLKINSQIKIDAHLNKVCP
490 500 510 520 530 540
160 170 180 190 200
pF1KB8 -----FNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEG
.:: :: . .:. .::.. :::.... .. : ::.:.:: :
XP_016 TTETIYNDEFYTKQDVIITALDNVEARRYVDSRCLANLR------------PLLDSGTMG
550 560 570 580 590
210 220 230 240 250 260
pF1KB8 FKGNARVILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFG
::...::.: .: . . ::. ..:.::. :.: :: :...:
XP_016 TKGHTEVIVPHLTESYNSHRD--PPEEEIPFCTLKSFPAAIEHTIQWARDKFESSFSHKP
600 610 620 630 640 650
270 280 290 300 310 320
pF1KB8 EGVPLGGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCA
XP_016 SLFNKFWQTYSSAEEVLQKIQSGHSLEGCFQVIKLLSRRPRNWSQCVELARLKFEKYFNH
660 670 680 690 700 710
>>NP_060697 (OMIM: 611361) ubiquitin-like modifier-activ (1052 aa)
initn: 460 init1: 139 opt: 306 Z-score: 380.8 bits: 80.9 E(85289): 1.8e-14
Smith-Waterman score: 372; 34.7% identity (61.8% similar) in 199 aa overlap (67-254:458-642)
40 50 60 70 80 90
pF1KB8 RWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFR--
:.. .....: :..:::.:::.:: :
NP_060 LGKPECEEFLPRGDRYDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTS
430 440 450 460 470 480
100 110 120 130 140 150
pF1KB8 ----QIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFYKIQD
.: : : : :. :::::::::::. : .::. .::. . .. :. :.
NP_060 KEKGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLKINSQIKIDAHLNKVCP
490 500 510 520 530 540
160 170 180 190 200
pF1KB8 -----FNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEG
.:: :: . .:. .::.. :::.... .. : ::.:.:: :
NP_060 TTETIYNDEFYTKQDVIITALDNVEARRYVDSRCLANLR------------PLLDSGTMG
550 560 570 580 590
210 220 230 240 250 260
pF1KB8 FKGNARVILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFG
::...::.: .: . . ::. ..:.::. :.: :: :...:
NP_060 TKGHTEVIVPHLTESYNSHRD--PPEEEIPFCTLKSFPAAIEHTIQWARDKFESSFSHKP
600 610 620 630 640 650
270 280 290 300 310 320
pF1KB8 EGVPLGGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCA
NP_060 SLFNKFWQTYSSAEEVLQKIQSGHSLEGCFQVIKLLSRRPRNWSQCVELARLKFEKYFNH
660 670 680 690 700 710
463 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:23:04 2016 done: Fri Nov 4 14:23:06 2016
Total Scan time: 8.820 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]