FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8670, 464 aa 1>>>pF1KB8670 464 - 464 aa - 464 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3861+/-0.000763; mu= 18.0530+/- 0.046 mean_var=75.0508+/-15.392, 0's: 0 Z-trim(109.7): 39 B-trim: 394 in 2/49 Lambda= 0.148046 statistics sampled from 11036 (11074) to 11036 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.34), width: 16 Scan time: 2.830 The best scores are: opt bits E(32554) CCDS5577.1 RCC1L gene_id:81554|Hs108|chr7 ( 464) 3167 685.6 2.9e-197 CCDS64683.1 RCC1L gene_id:81554|Hs108|chr7 ( 454) 3006 651.2 6.3e-187 CCDS64684.1 RCC1L gene_id:81554|Hs108|chr7 ( 358) 2377 516.8 1.4e-146 CCDS82939.1 HERC3 gene_id:8916|Hs108|chr4 ( 368) 432 101.4 1.7e-21 CCDS34028.1 HERC3 gene_id:8916|Hs108|chr4 (1050) 432 101.7 3.9e-21 CCDS60541.1 HERC4 gene_id:26091|Hs108|chr10 ( 979) 401 95.1 3.6e-19 CCDS7274.1 HERC4 gene_id:26091|Hs108|chr10 (1049) 401 95.1 3.8e-19 CCDS41533.1 HERC4 gene_id:26091|Hs108|chr10 (1057) 401 95.1 3.8e-19 CCDS54777.1 HERC6 gene_id:55008|Hs108|chr4 ( 986) 397 94.2 6.6e-19 CCDS47098.1 HERC6 gene_id:55008|Hs108|chr4 (1022) 397 94.2 6.7e-19 CCDS73571.1 RCBTB2 gene_id:1102|Hs108|chr13 ( 527) 375 89.3 1e-17 CCDS9411.1 RCBTB2 gene_id:1102|Hs108|chr13 ( 551) 375 89.3 1.1e-17 CCDS73572.1 RCBTB2 gene_id:1102|Hs108|chr13 ( 556) 375 89.3 1.1e-17 CCDS3630.1 HERC5 gene_id:51191|Hs108|chr4 (1024) 326 79.0 2.5e-14 CCDS7828.1 SERGEF gene_id:26297|Hs108|chr11 ( 458) 303 73.9 3.9e-13 CCDS9418.1 RCBTB1 gene_id:55213|Hs108|chr13 ( 531) 299 73.1 8e-13 CCDS14246.1 RPGR gene_id:6103|Hs108|chrX ( 815) 276 68.3 3.4e-11 CCDS35229.1 RPGR gene_id:6103|Hs108|chrX (1152) 276 68.4 4.5e-11 >>CCDS5577.1 RCC1L gene_id:81554|Hs108|chr7 (464 aa) initn: 3167 init1: 3167 opt: 3167 Z-score: 3655.1 bits: 685.6 E(32554): 2.9e-197 Smith-Waterman score: 3167; 99.6% identity (99.6% similar) in 464 aa overlap (1-464:1-464) 10 20 30 40 50 60 pF1KB8 MALVALVAGARLGRRLSGPGLGRGHWTAARRSRSRREAAEAEAEVPVVQYVGERAARADR ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: CCDS55 MALVALVAGARLGRRLSGPGLGRGHWTAAGRSRSRREAAEAEAEVPVVQYVGERAARADR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VFVWGFSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPYRLELDQKISSAACGYGFTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 VFVWGFSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPYRLELDQKISSAACGYGFTL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LSSKTADVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQETRVLQVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LSSKTADVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQETRVLQVS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 CGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHGMQDFDGQVVQVACGQD ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: CCDS55 CGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQVACGQD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 HSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 HSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 DGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 DGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFVW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 GYGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GYGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGK 370 380 390 400 410 420 430 440 450 460 pF1KB8 NIRGCLGIGRLEDQYFPWRVTMPGEPVDVACGVDHMVTLAKSFI :::::::::::::::::::::::::::::::::::::::::::: CCDS55 NIRGCLGIGRLEDQYFPWRVTMPGEPVDVACGVDHMVTLAKSFI 430 440 450 460 >>CCDS64683.1 RCC1L gene_id:81554|Hs108|chr7 (454 aa) initn: 3250 init1: 3006 opt: 3006 Z-score: 3469.4 bits: 651.2 E(32554): 6.3e-187 Smith-Waterman score: 3006; 98.9% identity (99.1% similar) in 443 aa overlap (1-443:1-443) 10 20 30 40 50 60 pF1KB8 MALVALVAGARLGRRLSGPGLGRGHWTAARRSRSRREAAEAEAEVPVVQYVGERAARADR ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: CCDS64 MALVALVAGARLGRRLSGPGLGRGHWTAAGRSRSRREAAEAEAEVPVVQYVGERAARADR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VFVWGFSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPYRLELDQKISSAACGYGFTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 VFVWGFSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPYRLELDQKISSAACGYGFTL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LSSKTADVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQETRVLQVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 LSSKTADVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQETRVLQVS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 CGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHGMQDFDGQVVQVACGQD ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: CCDS64 CGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQVACGQD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 HSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 HSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 DGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 DGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFVW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 GYGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 GYGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGK 370 380 390 400 410 420 430 440 450 460 pF1KB8 NIRGCLGIGRLEDQYFPWRVTMPGEPVDVACGVDHMVTLAKSFI :::::::::::::::::::. : CCDS64 NIRGCLGIGRLEDQYFPWRAPAPSASAKTTGPLL 430 440 450 >>CCDS64684.1 RCC1L gene_id:81554|Hs108|chr7 (358 aa) initn: 2377 init1: 2377 opt: 2377 Z-score: 2744.8 bits: 516.8 E(32554): 1.4e-146 Smith-Waterman score: 2377; 99.4% identity (99.4% similar) in 352 aa overlap (1-352:1-352) 10 20 30 40 50 60 pF1KB8 MALVALVAGARLGRRLSGPGLGRGHWTAARRSRSRREAAEAEAEVPVVQYVGERAARADR ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: CCDS64 MALVALVAGARLGRRLSGPGLGRGHWTAAGRSRSRREAAEAEAEVPVVQYVGERAARADR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VFVWGFSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPYRLELDQKISSAACGYGFTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 VFVWGFSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPYRLELDQKISSAACGYGFTL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LSSKTADVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQETRVLQVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 LSSKTADVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQETRVLQVS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 CGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHGMQDFDGQVVQVACGQD ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: CCDS64 CGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQVACGQD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 HSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 HSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 DGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFVW :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 DGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNDTWPQS 310 320 330 340 350 370 380 390 400 410 420 pF1KB8 GYGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGK >>CCDS82939.1 HERC3 gene_id:8916|Hs108|chr4 (368 aa) initn: 394 init1: 258 opt: 432 Z-score: 499.5 bits: 101.4 E(32554): 1.7e-21 Smith-Waterman score: 438; 31.2% identity (58.1% similar) in 308 aa overlap (158-462:22-312) 130 140 150 160 170 180 pF1KB8 VTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQETRVLQVSCGRAHSL : ::. .. :: : .:.:: ::. CCDS82 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRS----VKEVACGGNHSV 10 20 30 40 190 200 210 220 230 240 pF1KB8 VLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHGMQDFDGQVVQVACGQDHSLFLTD : . :.. : :. :: :.. :. ... .. : ....::::..::: :.: CCDS82 FLLEDGEVYTCGLNTKGQLGHEREGNK----PEQIGALA--DQHIIHVACGESHSLALSD 50 60 70 80 90 100 250 260 270 280 290 300 pF1KB8 KGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSADGGLFGW .:...: : :.::: :: . . . .: : ...::. . :::..::: .: : CCDS82 RGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTW 110 120 130 140 150 160 310 320 330 340 350 360 pF1KB8 GNSEYLQLASVTD-STQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFVWGYGILG :.. . ::. . .:.. : . :. . :.: ::. .:. : :: ::.. : CCDS82 GKNSHGQLGLGKEFPSQASPQRVRSLEGI-PLAQVAAGGAHSFALSLSGAVFGWGMNNAG 170 180 190 200 210 220 370 380 390 400 410 420 pF1KB8 KGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGKNIRGCL . : : . : : . . .: : :: : :.::..: .:..: . : : CCDS82 Q---LGLSDEKDRESPCHVKLLRTQ---KVVYISCGEEHTAVLTKSGGVFTFGAGSCGQL 230 240 250 260 270 430 440 450 460 pF1KB8 GIGRLEDQYFPWRVT--MPGEPVDVACGVDHMVTLAKSFI : ..:. : :: : .: ...::: .: .... : CCDS82 GHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCN 280 290 300 310 320 330 CCDS82 VKCPSPVKGYWAAHSGQLSARAGKNDCLWNLKVF 340 350 360 >>CCDS34028.1 HERC3 gene_id:8916|Hs108|chr4 (1050 aa) initn: 394 init1: 258 opt: 432 Z-score: 493.0 bits: 101.7 E(32554): 3.9e-21 Smith-Waterman score: 438; 31.2% identity (58.1% similar) in 308 aa overlap (158-462:22-312) 130 140 150 160 170 180 pF1KB8 VTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQETRVLQVSCGRAHSL : ::. .. :: : .:.:: ::. CCDS34 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRS----VKEVACGGNHSV 10 20 30 40 190 200 210 220 230 240 pF1KB8 VLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHGMQDFDGQVVQVACGQDHSLFLTD : . :.. : :. :: :.. :. ... .. : ....::::..::: :.: CCDS34 FLLEDGEVYTCGLNTKGQLGHEREGNK----PEQIGALA--DQHIIHVACGESHSLALSD 50 60 70 80 90 100 250 260 270 280 290 300 pF1KB8 KGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSADGGLFGW .:...: : :.::: :: . . . .: : ...::. . :::..::: .: : CCDS34 RGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTW 110 120 130 140 150 160 310 320 330 340 350 360 pF1KB8 GNSEYLQLASVTD-STQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFVWGYGILG :.. . ::. . .:.. : . :. . :.: ::. .:. : :: ::.. : CCDS34 GKNSHGQLGLGKEFPSQASPQRVRSLEGI-PLAQVAAGGAHSFALSLSGAVFGWGMNNAG 170 180 190 200 210 220 370 380 390 400 410 420 pF1KB8 KGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGKNIRGCL . : : . : : . . .: : :: : :.::..: .:..: . : : CCDS34 Q---LGLSDEKDRESPCHVKLLRTQ---KVVYISCGEEHTAVLTKSGGVFTFGAGSCGQL 230 240 250 260 270 430 440 450 460 pF1KB8 GIGRLEDQYFPWRVT--MPGEPVDVACGVDHMVTLAKSFI : ..:. : :: : .: ...::: .: .... : CCDS34 GHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCN 280 290 300 310 320 330 CCDS34 VKCPSPVKGYWAAHSGQLSARADRFKYHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMN 340 350 360 370 380 390 >>CCDS60541.1 HERC4 gene_id:26091|Hs108|chr10 (979 aa) initn: 418 init1: 226 opt: 401 Z-score: 457.6 bits: 95.1 E(32554): 3.6e-19 Smith-Waterman score: 464; 31.2% identity (57.9% similar) in 349 aa overlap (96-440:23-341) 70 80 90 100 110 120 pF1KB8 FSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPYRLELDQKISSAACGYGFTLLSSKT ..: . ..... ...:: :.. . CCDS60 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVF---V 10 20 30 40 130 140 150 160 170 180 pF1KB8 ADVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQETRVLQVSCGRAH : :. : : .::: ..::: .: : . :: . .. ::::.:: CCDS60 LDDGTVYTCGCNDLGQLGHEKSRK----------KPEQV-VALDAQN---IVAVSCGEAH 50 60 70 80 90 190 200 210 220 230 240 pF1KB8 SLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHGMQDFDGQVVQVACGQDHSLFL .:.:.:. :.. : .: :: : : .: . .....:. :.:::::: ::: : CCDS60 TLALNDKGQVYAWGLDSDGQLGL-VGSEECIRVPRNIKSLSDI--QIVQVACGYYHSLAL 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB8 TDKGEVYSCGWGAD--GQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSADGG . .::. : :: . :: ::: .. .: .: :. .:::. : .... .:. CCDS60 SKASEVF-C-WGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGA 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB8 LFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFVWGYG .:::: ... ::. ..: .. :: :. :. :: :.:. :: ::..: : CCDS60 IFGWGRNKFGQLG-LNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAG 220 230 240 250 260 370 380 390 400 410 420 pF1KB8 ILGK-GPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALT-NKGELFVWGKN :. : : :. :. : .: :. : :..: :: .: .:.. ..:... .: . CCDS60 GYGQLGHN---STSHEINPRKVF---ELMGSI-VTEIACGRQHTSAFVPSSGRIYSFGLG 270 280 290 300 310 320 430 440 450 460 pF1KB8 IRGCLGIGRLEDQYFPWRVTMPGEPVDVACGVDHMVTLAKSFI : :: : .. :. : CCDS60 GNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSPQ 330 340 350 360 370 380 >>CCDS7274.1 HERC4 gene_id:26091|Hs108|chr10 (1049 aa) initn: 418 init1: 226 opt: 401 Z-score: 457.2 bits: 95.1 E(32554): 3.8e-19 Smith-Waterman score: 464; 31.2% identity (57.9% similar) in 349 aa overlap (96-440:23-341) 70 80 90 100 110 120 pF1KB8 FSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPYRLELDQKISSAACGYGFTLLSSKT ..: . ..... ...:: :.. . CCDS72 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVF---V 10 20 30 40 130 140 150 160 170 180 pF1KB8 ADVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQETRVLQVSCGRAH : :. : : .::: ..::: .: : . :: . .. ::::.:: CCDS72 LDDGTVYTCGCNDLGQLGHEKSRK----------KPEQV-VALDAQN---IVAVSCGEAH 50 60 70 80 90 190 200 210 220 230 240 pF1KB8 SLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHGMQDFDGQVVQVACGQDHSLFL .:.:.:. :.. : .: :: : : .: . .....:. :.:::::: ::: : CCDS72 TLALNDKGQVYAWGLDSDGQLGL-VGSEECIRVPRNIKSLSDI--QIVQVACGYYHSLAL 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB8 TDKGEVYSCGWGAD--GQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSADGG . .::. : :: . :: ::: .. .: .: :. .:::. : .... .:. CCDS72 SKASEVF-C-WGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGA 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB8 LFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFVWGYG .:::: ... ::. ..: .. :: :. :. :: :.:. :: ::..: : CCDS72 IFGWGRNKFGQLG-LNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAG 220 230 240 250 260 370 380 390 400 410 420 pF1KB8 ILGK-GPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALT-NKGELFVWGKN :. : : :. :. : .: :. : :..: :: .: .:.. ..:... .: . CCDS72 GYGQLGHN---STSHEINPRKVF---ELMGSI-VTEIACGRQHTSAFVPSSGRIYSFGLG 270 280 290 300 310 320 430 440 450 460 pF1KB8 IRGCLGIGRLEDQYFPWRVTMPGEPVDVACGVDHMVTLAKSFI : :: : .. :. : CCDS72 GNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSPQ 330 340 350 360 370 380 >>CCDS41533.1 HERC4 gene_id:26091|Hs108|chr10 (1057 aa) initn: 418 init1: 226 opt: 401 Z-score: 457.2 bits: 95.1 E(32554): 3.8e-19 Smith-Waterman score: 464; 31.2% identity (57.9% similar) in 349 aa overlap (96-440:23-341) 70 80 90 100 110 120 pF1KB8 FSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPYRLELDQKISSAACGYGFTLLSSKT ..: . ..... ...:: :.. . CCDS41 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVF---V 10 20 30 40 130 140 150 160 170 180 pF1KB8 ADVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQETRVLQVSCGRAH : :. : : .::: ..::: .: : . :: . .. ::::.:: CCDS41 LDDGTVYTCGCNDLGQLGHEKSRK----------KPEQV-VALDAQN---IVAVSCGEAH 50 60 70 80 90 190 200 210 220 230 240 pF1KB8 SLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHGMQDFDGQVVQVACGQDHSLFL .:.:.:. :.. : .: :: : : .: . .....:. :.:::::: ::: : CCDS41 TLALNDKGQVYAWGLDSDGQLGL-VGSEECIRVPRNIKSLSDI--QIVQVACGYYHSLAL 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB8 TDKGEVYSCGWGAD--GQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSADGG . .::. : :: . :: ::: .. .: .: :. .:::. : .... .:. CCDS41 SKASEVF-C-WGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGA 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB8 LFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFVWGYG .:::: ... ::. ..: .. :: :. :. :: :.:. :: ::..: : CCDS41 IFGWGRNKFGQLG-LNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAG 220 230 240 250 260 370 380 390 400 410 420 pF1KB8 ILGK-GPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALT-NKGELFVWGKN :. : : :. :. : .: :. : :..: :: .: .:.. ..:... .: . CCDS41 GYGQLGHN---STSHEINPRKVF---ELMGSI-VTEIACGRQHTSAFVPSSGRIYSFGLG 270 280 290 300 310 320 430 440 450 460 pF1KB8 IRGCLGIGRLEDQYFPWRVTMPGEPVDVACGVDHMVTLAKSFI : :: : .. :. : CCDS41 GNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSPQ 330 340 350 360 370 380 >>CCDS54777.1 HERC6 gene_id:55008|Hs108|chr4 (986 aa) initn: 296 init1: 211 opt: 397 Z-score: 453.0 bits: 94.2 E(32554): 6.6e-19 Smith-Waterman score: 397; 31.7% identity (57.2% similar) in 290 aa overlap (176-460:25-301) 150 160 170 180 190 200 pF1KB8 RSRKDKTRGYEYVLEPSPVSLPLDRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQ .::.. :. :::.: . :.: :.:: :: CCDS54 MYFCWGADSRELQRRRTAGSPGAELLQAASGERHSLLLLTNHRVLSCGDNSRGQ 10 20 30 40 50 210 220 230 240 250 260 pF1KB8 CGRKVVENEIYSESHRVHGMQDFDGQVVQ-VACGQDHSLFLTDKGEVYSCGWGADGQTGL ::. .. : .: .. .:. :.::..::: . ::.:.. : :..:: :. CCDS54 LGRRGAQRGELPEP-----IQALETLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGI 60 70 80 90 100 270 280 290 300 310 320 pF1KB8 GHYN-ITSSPTKLGGDLAGVNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTD-ST :... :. .: :. : ...:::. ::.: :. .:.::.. . ::. . . CCDS54 GEFKEISFTPKKIM-TLNDIKIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPS 110 120 130 140 150 160 330 340 350 360 370 380 pF1KB8 QVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFVWGYGILGKGPNLVESAVP-EMIP :.. : . :. . :.: ::. .:. : : :: . :. : :: . CCDS54 QASPQRVRSLEGI-PLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLA-LSGRNVPVQSNK 170 180 190 200 210 220 390 400 410 420 430 440 pF1KB8 PTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRVT : : . .. : : :: .: :.::. :..:..: : : :: . .. : : CCDS54 PLSVGALK---NLGVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVE 230 240 250 260 270 280 450 460 pF1KB8 -MPGEPVDVACGVDHMVTLAKSFI . : .. :: : ::: CCDS54 RIDGLVSQIDCGSYH--TLAYVHTTGQVVSFGHGPSDTSKPTHPEALTENFDISCLISAE 290 300 310 320 330 340 >>CCDS47098.1 HERC6 gene_id:55008|Hs108|chr4 (1022 aa) initn: 296 init1: 211 opt: 397 Z-score: 452.7 bits: 94.2 E(32554): 6.7e-19 Smith-Waterman score: 397; 31.7% identity (57.2% similar) in 290 aa overlap (176-460:25-301) 150 160 170 180 190 200 pF1KB8 RSRKDKTRGYEYVLEPSPVSLPLDRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQ .::.. :. :::.: . :.: :.:: :: CCDS47 MYFCWGADSRELQRRRTAGSPGAELLQAASGERHSLLLLTNHRVLSCGDNSRGQ 10 20 30 40 50 210 220 230 240 250 260 pF1KB8 CGRKVVENEIYSESHRVHGMQDFDGQVVQ-VACGQDHSLFLTDKGEVYSCGWGADGQTGL ::. .. : .: .. .:. :.::..::: . ::.:.. : :..:: :. CCDS47 LGRRGAQRGELPEP-----IQALETLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGI 60 70 80 90 100 270 280 290 300 310 320 pF1KB8 GHYN-ITSSPTKLGGDLAGVNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTD-ST :... :. .: :. : ...:::. ::.: :. .:.::.. . ::. . . CCDS47 GEFKEISFTPKKIM-TLNDIKIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPS 110 120 130 140 150 160 330 340 350 360 370 380 pF1KB8 QVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFVWGYGILGKGPNLVESAVP-EMIP :.. : . :. . :.: ::. .:. : : :: . :. : :: . CCDS47 QASPQRVRSLEGI-PLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLA-LSGRNVPVQSNK 170 180 190 200 210 220 390 400 410 420 430 440 pF1KB8 PTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRVT : : . .. : : :: .: :.::. :..:..: : : :: . .. : : CCDS47 PLSVGALK---NLGVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVE 230 240 250 260 270 280 450 460 pF1KB8 -MPGEPVDVACGVDHMVTLAKSFI . : .. :: : ::: CCDS47 RIDGLVSQIDCGSYH--TLAYVHTTGQVVSFGHGPSDTSKPTHPEALTENFDISCLISAE 290 300 310 320 330 340 464 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:24:53 2016 done: Fri Nov 4 14:24:53 2016 Total Scan time: 2.830 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]