FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8672, 571 aa 1>>>pF1KB8672 571 - 571 aa - 571 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2656+/-0.000473; mu= 18.8205+/- 0.029 mean_var=62.1643+/-12.519, 0's: 0 Z-trim(108.6): 64 B-trim: 11 in 1/54 Lambda= 0.162669 statistics sampled from 16658 (16693) to 16658 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.537), E-opt: 0.2 (0.196), width: 16 Scan time: 8.280 The best scores are: opt bits E(85289) NP_055400 (OMIM: 604653,606069) solute carrier fam ( 571) 3724 883.2 0 XP_016859427 (OMIM: 604653,606069) PREDICTED: solu ( 531) 3440 816.5 0 XP_005246562 (OMIM: 604653,606069) PREDICTED: solu ( 531) 3440 816.5 0 >>NP_055400 (OMIM: 604653,606069) solute carrier family (571 aa) initn: 3724 init1: 3724 opt: 3724 Z-score: 4719.7 bits: 883.2 E(85289): 0 Smith-Waterman score: 3724; 100.0% identity (100.0% similar) in 571 aa overlap (1-571:1-571) 10 20 30 40 50 60 pF1KB8 MTRAGDHNRQRGCCGSLADYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MTRAGDHNRQRGCCGSLADYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LTMYHGWVLTSCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LTMYHGWVLTSCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 DQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 EEETELKQLNLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EEETELKQLNLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 SYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 TKIPEITTEIYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TKIPEITTEIYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 QENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFR 490 500 510 520 530 540 550 560 570 pF1KB8 FAQNTLGNKLFACGPDAKEVRKENQANTSVV ::::::::::::::::::::::::::::::: NP_055 FAQNTLGNKLFACGPDAKEVRKENQANTSVV 550 560 570 >>XP_016859427 (OMIM: 604653,606069) PREDICTED: solute c (531 aa) initn: 3440 init1: 3440 opt: 3440 Z-score: 4360.0 bits: 816.5 E(85289): 0 Smith-Waterman score: 3440; 100.0% identity (100.0% similar) in 531 aa overlap (41-571:1-531) 20 30 40 50 60 70 pF1KB8 RGCCGSLADYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVAG :::::::::::::::::::::::::::::: XP_016 MWHFAVSVFLVELYGNSLLLTAVYGLVVAG 10 20 30 80 90 100 110 120 130 pF1KB8 SVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHELLTMYHGWVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHELLTMYHGWVLT 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB8 SCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRIDQLTNILAPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRIDQLTNILAPM 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB8 AVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLKEEETELKQLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLKEEETELKQLN 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB8 LHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWVSYYNQPVFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWVSYYNQPVFLA 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB8 GMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAFTWLRRKCGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAFTWLRRKCGLV 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB8 RTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITPTKIPEITTEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITPTKIPEITTEI 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB8 YMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERG 400 410 420 430 440 450 500 510 520 530 540 550 pF1KB8 IINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFRFAQNTLGNKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFRFAQNTLGNKL 460 470 480 490 500 510 560 570 pF1KB8 FACGPDAKEVRKENQANTSVV ::::::::::::::::::::: XP_016 FACGPDAKEVRKENQANTSVV 520 530 >>XP_005246562 (OMIM: 604653,606069) PREDICTED: solute c (531 aa) initn: 3440 init1: 3440 opt: 3440 Z-score: 4360.0 bits: 816.5 E(85289): 0 Smith-Waterman score: 3440; 100.0% identity (100.0% similar) in 531 aa overlap (41-571:1-531) 20 30 40 50 60 70 pF1KB8 RGCCGSLADYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVAG :::::::::::::::::::::::::::::: XP_005 MWHFAVSVFLVELYGNSLLLTAVYGLVVAG 10 20 30 80 90 100 110 120 130 pF1KB8 SVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHELLTMYHGWVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHELLTMYHGWVLT 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB8 SCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRIDQLTNILAPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRIDQLTNILAPM 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB8 AVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLKEEETELKQLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLKEEETELKQLN 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB8 LHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWVSYYNQPVFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWVSYYNQPVFLA 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB8 GMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAFTWLRRKCGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAFTWLRRKCGLV 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB8 RTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITPTKIPEITTEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITPTKIPEITTEI 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB8 YMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERG 400 410 420 430 440 450 500 510 520 530 540 550 pF1KB8 IINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFRFAQNTLGNKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFRFAQNTLGNKL 460 470 480 490 500 510 560 570 pF1KB8 FACGPDAKEVRKENQANTSVV ::::::::::::::::::::: XP_005 FACGPDAKEVRKENQANTSVV 520 530 571 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:26:10 2016 done: Fri Nov 4 14:26:11 2016 Total Scan time: 8.280 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]