FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8673, 657 aa
1>>>pF1KB8673 657 - 657 aa - 657 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6553+/-0.000336; mu= 18.5797+/- 0.021
mean_var=87.7813+/-17.874, 0's: 0 Z-trim(116.4): 77 B-trim: 95 in 1/52
Lambda= 0.136890
statistics sampled from 27518 (27598) to 27518 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.324), width: 16
Scan time: 11.400
The best scores are: opt bits E(85289)
NP_001171646 (OMIM: 612480) TCDD-inducible poly [A ( 657) 4547 908.3 0
NP_056323 (OMIM: 612480) TCDD-inducible poly [ADP- ( 657) 4547 908.3 0
NP_001171647 (OMIM: 612480) TCDD-inducible poly [A ( 657) 4547 908.3 0
NP_073587 (OMIM: 612481) poly [ADP-ribose] polymer ( 701) 734 155.2 7.3e-37
XP_011510781 (OMIM: 612066) PREDICTED: poly [ADP-r ( 425) 486 106.1 2.7e-22
XP_011510780 (OMIM: 612066) PREDICTED: poly [ADP-r ( 425) 486 106.1 2.7e-22
XP_016861281 (OMIM: 612066) PREDICTED: poly [ADP-r ( 425) 486 106.1 2.7e-22
NP_689828 (OMIM: 612066) poly [ADP-ribose] polymer ( 444) 486 106.1 2.8e-22
NP_001295250 (OMIM: 612066) poly [ADP-ribose] poly ( 375) 484 105.7 3.3e-22
XP_011510779 (OMIM: 612066) PREDICTED: poly [ADP-r ( 552) 486 106.2 3.3e-22
XP_005247217 (OMIM: 612066) PREDICTED: poly [ADP-r ( 602) 486 106.2 3.6e-22
XP_011510778 (OMIM: 612066) PREDICTED: poly [ADP-r ( 628) 486 106.2 3.7e-22
XP_011510777 (OMIM: 612066) PREDICTED: poly [ADP-r ( 638) 486 106.2 3.7e-22
NP_001106995 (OMIM: 612066) poly [ADP-ribose] poly ( 678) 486 106.3 3.9e-22
NP_001295249 (OMIM: 612066) poly [ADP-ribose] poly ( 483) 484 105.8 4e-22
XP_016861280 (OMIM: 612066) PREDICTED: poly [ADP-r ( 533) 484 105.8 4.3e-22
XP_005247216 (OMIM: 612066) PREDICTED: poly [ADP-r ( 609) 484 105.8 4.7e-22
NP_060024 (OMIM: 610028) poly [ADP-ribose] polymer (1801) 451 99.7 1e-19
XP_011515638 (OMIM: 609564) PREDICTED: poly [ADP-r (1016) 383 86.0 7.1e-16
NP_116178 (OMIM: 609564) poly [ADP-ribose] polymer (1025) 383 86.0 7.2e-16
NP_001304824 (OMIM: 609564) poly [ADP-ribose] poly (1037) 383 86.1 7.2e-16
XP_016875160 (OMIM: 616706) PREDICTED: poly [ADP-r ( 257) 332 75.5 2.6e-13
NP_001273451 (OMIM: 616706) poly [ADP-ribose] poly ( 257) 332 75.5 2.6e-13
NP_001273450 (OMIM: 616706) poly [ADP-ribose] poly ( 257) 332 75.5 2.6e-13
XP_005253768 (OMIM: 616706) PREDICTED: poly [ADP-r ( 331) 332 75.6 3.2e-13
XP_011519273 (OMIM: 616706) PREDICTED: poly [ADP-r ( 331) 332 75.6 3.2e-13
XP_011519275 (OMIM: 616706) PREDICTED: poly [ADP-r ( 331) 332 75.6 3.2e-13
XP_011519272 (OMIM: 616706) PREDICTED: poly [ADP-r ( 331) 332 75.6 3.2e-13
XP_016875159 (OMIM: 616706) PREDICTED: poly [ADP-r ( 331) 332 75.6 3.2e-13
NP_065100 (OMIM: 616706) poly [ADP-ribose] polymer ( 338) 332 75.6 3.3e-13
NP_064504 (OMIM: 607312) zinc finger CCCH-type ant ( 902) 268 63.3 4.5e-09
XP_005250558 (OMIM: 607312) PREDICTED: zinc finger (1024) 268 63.3 4.9e-09
NP_001139575 (OMIM: 612065) poly [ADP-ribose] poly ( 819) 247 59.1 7.3e-08
XP_016862795 (OMIM: 612065) PREDICTED: poly [ADP-r ( 819) 247 59.1 7.3e-08
NP_001139577 (OMIM: 612065) poly [ADP-ribose] poly ( 819) 247 59.1 7.3e-08
NP_001139576 (OMIM: 612065) poly [ADP-ribose] poly ( 819) 247 59.1 7.3e-08
XP_016862794 (OMIM: 612065) PREDICTED: poly [ADP-r ( 819) 247 59.1 7.3e-08
XP_005247877 (OMIM: 612065) PREDICTED: poly [ADP-r ( 854) 247 59.1 7.6e-08
NP_113646 (OMIM: 612065) poly [ADP-ribose] polymer ( 854) 247 59.1 7.6e-08
NP_001139574 (OMIM: 612065) poly [ADP-ribose] poly ( 854) 247 59.1 7.6e-08
XP_016862793 (OMIM: 612065) PREDICTED: poly [ADP-r ( 854) 247 59.1 7.6e-08
XP_005250097 (OMIM: 612481) PREDICTED: poly [ADP-r ( 416) 220 53.6 1.8e-06
XP_005250096 (OMIM: 612481) PREDICTED: poly [ADP-r ( 420) 220 53.6 1.8e-06
XP_005250095 (OMIM: 612481) PREDICTED: poly [ADP-r ( 487) 220 53.6 2e-06
XP_011514793 (OMIM: 612481) PREDICTED: poly [ADP-r ( 535) 220 53.6 2.1e-06
XP_011538517 (OMIM: 607128) PREDICTED: tankyrase-2 ( 695) 190 47.8 0.00016
XP_016872189 (OMIM: 607128) PREDICTED: tankyrase-2 ( 977) 177 45.4 0.0012
XP_016872188 (OMIM: 607128) PREDICTED: tankyrase-2 (1059) 177 45.4 0.0013
XP_016872187 (OMIM: 607128) PREDICTED: tankyrase-2 (1062) 177 45.4 0.0013
XP_016872186 (OMIM: 607128) PREDICTED: tankyrase-2 (1062) 177 45.4 0.0013
>>NP_001171646 (OMIM: 612480) TCDD-inducible poly [ADP-r (657 aa)
initn: 4547 init1: 4547 opt: 4547 Z-score: 4853.0 bits: 908.3 E(85289): 0
Smith-Waterman score: 4547; 100.0% identity (100.0% similar) in 657 aa overlap (1-657:1-657)
10 20 30 40 50 60
pF1KB8 MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 NTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 IPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 EICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 MRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 VPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 FHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 GICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGS
550 560 570 580 590 600
610 620 630 640 650
pF1KB8 HGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI
610 620 630 640 650
>>NP_056323 (OMIM: 612480) TCDD-inducible poly [ADP-ribo (657 aa)
initn: 4547 init1: 4547 opt: 4547 Z-score: 4853.0 bits: 908.3 E(85289): 0
Smith-Waterman score: 4547; 100.0% identity (100.0% similar) in 657 aa overlap (1-657:1-657)
10 20 30 40 50 60
pF1KB8 MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 NTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 IPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 EICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 MRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 VPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 FHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 GICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGS
550 560 570 580 590 600
610 620 630 640 650
pF1KB8 HGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI
610 620 630 640 650
>>NP_001171647 (OMIM: 612480) TCDD-inducible poly [ADP-r (657 aa)
initn: 4547 init1: 4547 opt: 4547 Z-score: 4853.0 bits: 908.3 E(85289): 0
Smith-Waterman score: 4547; 100.0% identity (100.0% similar) in 657 aa overlap (1-657:1-657)
10 20 30 40 50 60
pF1KB8 MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKDQKRLGTGTLRSLRPIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 NTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPPAENNMSVLIPDRTNVGDQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 IPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQTDLLHPVSSDVPTSPDCLDK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEASLDLVFELVNQLQYHTHQENGI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 EICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 MRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTPPSSNVNSIYHTVWKFFCRDHFGWREY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PESVIRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILLPYLQTLGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 VPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 FHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 GICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGS
550 560 570 580 590 600
610 620 630 640 650
pF1KB8 HGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI
610 620 630 640 650
>>NP_073587 (OMIM: 612481) poly [ADP-ribose] polymerase (701 aa)
initn: 546 init1: 252 opt: 734 Z-score: 782.8 bits: 155.2 E(85289): 7.3e-37
Smith-Waterman score: 734; 33.4% identity (63.4% similar) in 434 aa overlap (236-652:269-681)
210 220 230 240 250 260
pF1KB8 LSTELFQDKSEEASLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLP
::.: .::. .. .: . : . : ::
NP_073 APSRVPPLFVPQGTSERKDSSGSVSPNTLSQEEGDQICLYHIRKSCSFQDKCHRVHFHLP
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB8 YHWQIKRTTTQKWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWA---DLNAMNVYET
:.::. ::... :..: .:. ::::. .:. . ... : . ..:::. : .
NP_073 YRWQF--LDRGKWEDL--DNMELIEEAYCNPKIERILCSESASTFHSHCLNFNAMT-YGA
300 310 320 330 340 350
330 340 350 360 370
pF1KB8 TEFDQLRRLSTPPSSNVNSIYHTV----WKFFCRDHFG-WREYP-ESVIRLIEEANSRGL
: : ::::: .:.:.. : . : .. :.:: :.:: ..... . ..: .
NP_073 T---QARRLST--ASSVTKPPHFILTTDWIWYWSDEFGSWQEYGRQGTVHPVTTVSSSDV
360 370 380 390 400
380 390 400 410 420
pF1KB8 KEVRFMMWNNHYILHNSFFRREIKRRPL---FRSCFIL--LPYLQT--LGGVPTQAPPPL
... . . . . . .. . .. :.. :. : : : . : . :
NP_073 EKAYLAYCTPGSDGQAATLKFQAGKHNYELDFKA-FVQKNLVYGTTKKVCRRPKYVSP--
410 420 430 440 450 460
430 440 450 460 470 480
pF1KB8 EATSSSQIICPDGVTSANFYPETW-VYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEF
. ... : : . . :. : :. : .. .:. .. :. ..:::..:.: :
NP_073 QDVTTMQT-CNTKFPGPKSIPDYWDSSALPDPGFQKITLSSSSEEYQKVWNLFNRTLP-F
470 480 490 500 510 520
490 500 510 520 530 540
pF1KB8 KYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFD
: . .: :::: ::: :. .: :... :. ..::.:::::: ::.::..:::
NP_073 -YFVQKIERVQNLALWEVYQWQKGQMQKQNGGK--AVDERQLFHGTSAIFVDAICQQNFD
530 540 550 560 570 580
550 560 570 580 590 600
pF1KB8 PRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPP
:::: :.: .:.:::::. :.:::..::.... .: ::::.::.:... :. .. :::
NP_073 WRVCGVHGTSYGKGSYFARDAAYSHHYSKSDTQ-THTMFLARVLVGEFVRGNASFVRPP-
590 600 610 620 630
610 620 630 640 650
pF1KB8 VNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI
.. : .. .:::::.. .:.:::::. : :: .:::: :
NP_073 AKEG-WSNAFYDSCVNSVSDPSIFVIFEKHQVYPEYVIQYTTSSKPSVTPSILLALGSLF
640 650 660 670 680 690
NP_073 SSRQ
700
>>XP_011510781 (OMIM: 612066) PREDICTED: poly [ADP-ribos (425 aa)
initn: 455 init1: 159 opt: 486 Z-score: 521.2 bits: 106.1 E(85289): 2.7e-22
Smith-Waterman score: 486; 41.1% identity (66.5% similar) in 209 aa overlap (443-648:224-423)
420 430 440 450 460 470
pF1KB8 PYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDK
.:. :. :: :. :. : : .: . ..
XP_011 IFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNL-PEHWTDMN-HQLFCMVQLEPGQS
200 210 220 230 240 250
480 490 500 510 520 530
pF1KB8 SYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFH
: : . : .: .: : .: :.:: :::..:. ::. :. : :. ::: :::
XP_011 EYNTIKDKFTRTCS--SYAIEKIERIQNAFLWQSYQVKKRQMDIK---NDHKNNERLLFH
260 270 280 290 300
540 550 560 570 580
pF1KB8 GTSQDVVDGICKHNFDPRVC-GKHATMFGQGSYFAKKASYS--HNFSKKSSKGVHFMFLA
::. : : . .:.:. : : ::.:. .:.:.::: :::: ..:: .:.: . :...
XP_011 GTDADSVPYVNQHGFN-RSCAGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVV
310 320 330 340 350 360
590 600 610 620 630 640
pF1KB8 KVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYE
.:::: .: : :. ::: :: . : ::.:: ..: :..::.: :.:.:: ..: .
XP_011 RVLTGVFTKGRAGLVTPPPKNPHNPT-DLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT
370 380 390 400 410 420
650
pF1KB8 EVSNTVSI
XP_011 A
>>XP_011510780 (OMIM: 612066) PREDICTED: poly [ADP-ribos (425 aa)
initn: 455 init1: 159 opt: 486 Z-score: 521.2 bits: 106.1 E(85289): 2.7e-22
Smith-Waterman score: 486; 41.1% identity (66.5% similar) in 209 aa overlap (443-648:224-423)
420 430 440 450 460 470
pF1KB8 PYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDK
.:. :. :: :. :. : : .: . ..
XP_011 IFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNL-PEHWTDMN-HQLFCMVQLEPGQS
200 210 220 230 240 250
480 490 500 510 520 530
pF1KB8 SYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFH
: : . : .: .: : .: :.:: :::..:. ::. :. : :. ::: :::
XP_011 EYNTIKDKFTRTCS--SYAIEKIERIQNAFLWQSYQVKKRQMDIK---NDHKNNERLLFH
260 270 280 290 300
540 550 560 570 580
pF1KB8 GTSQDVVDGICKHNFDPRVC-GKHATMFGQGSYFAKKASYS--HNFSKKSSKGVHFMFLA
::. : : . .:.:. : : ::.:. .:.:.::: :::: ..:: .:.: . :...
XP_011 GTDADSVPYVNQHGFN-RSCAGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVV
310 320 330 340 350 360
590 600 610 620 630 640
pF1KB8 KVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYE
.:::: .: : :. ::: :: . : ::.:: ..: :..::.: :.:.:: ..: .
XP_011 RVLTGVFTKGRAGLVTPPPKNPHNPT-DLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT
370 380 390 400 410 420
650
pF1KB8 EVSNTVSI
XP_011 A
>>XP_016861281 (OMIM: 612066) PREDICTED: poly [ADP-ribos (425 aa)
initn: 455 init1: 159 opt: 486 Z-score: 521.2 bits: 106.1 E(85289): 2.7e-22
Smith-Waterman score: 486; 41.1% identity (66.5% similar) in 209 aa overlap (443-648:224-423)
420 430 440 450 460 470
pF1KB8 PYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDK
.:. :. :: :. :. : : .: . ..
XP_016 IFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNL-PEHWTDMN-HQLFCMVQLEPGQS
200 210 220 230 240 250
480 490 500 510 520 530
pF1KB8 SYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFH
: : . : .: .: : .: :.:: :::..:. ::. :. : :. ::: :::
XP_016 EYNTIKDKFTRTCS--SYAIEKIERIQNAFLWQSYQVKKRQMDIK---NDHKNNERLLFH
260 270 280 290 300
540 550 560 570 580
pF1KB8 GTSQDVVDGICKHNFDPRVC-GKHATMFGQGSYFAKKASYS--HNFSKKSSKGVHFMFLA
::. : : . .:.:. : : ::.:. .:.:.::: :::: ..:: .:.: . :...
XP_016 GTDADSVPYVNQHGFN-RSCAGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVV
310 320 330 340 350 360
590 600 610 620 630 640
pF1KB8 KVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYE
.:::: .: : :. ::: :: . : ::.:: ..: :..::.: :.:.:: ..: .
XP_016 RVLTGVFTKGRAGLVTPPPKNPHNPT-DLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT
370 380 390 400 410 420
650
pF1KB8 EVSNTVSI
XP_016 A
>>NP_689828 (OMIM: 612066) poly [ADP-ribose] polymerase (444 aa)
initn: 455 init1: 159 opt: 486 Z-score: 520.9 bits: 106.1 E(85289): 2.8e-22
Smith-Waterman score: 486; 41.1% identity (66.5% similar) in 209 aa overlap (443-648:243-442)
420 430 440 450 460 470
pF1KB8 PYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDK
.:. :. :: :. :. : : .: . ..
NP_689 IFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNL-PEHWTDMN-HQLFCMVQLEPGQS
220 230 240 250 260 270
480 490 500 510 520 530
pF1KB8 SYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFH
: : . : .: .: : .: :.:: :::..:. ::. :. : :. ::: :::
NP_689 EYNTIKDKFTRTCS--SYAIEKIERIQNAFLWQSYQVKKRQMDIK---NDHKNNERLLFH
280 290 300 310 320
540 550 560 570 580
pF1KB8 GTSQDVVDGICKHNFDPRVC-GKHATMFGQGSYFAKKASYS--HNFSKKSSKGVHFMFLA
::. : : . .:.:. : : ::.:. .:.:.::: :::: ..:: .:.: . :...
NP_689 GTDADSVPYVNQHGFN-RSCAGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVV
330 340 350 360 370 380
590 600 610 620 630 640
pF1KB8 KVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYE
.:::: .: : :. ::: :: . : ::.:: ..: :..::.: :.:.:: ..: .
NP_689 RVLTGVFTKGRAGLVTPPPKNPHNPT-DLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT
390 400 410 420 430 440
650
pF1KB8 EVSNTVSI
NP_689 A
>>NP_001295250 (OMIM: 612066) poly [ADP-ribose] polymera (375 aa)
initn: 455 init1: 159 opt: 484 Z-score: 519.8 bits: 105.7 E(85289): 3.3e-22
Smith-Waterman score: 484; 39.2% identity (65.8% similar) in 222 aa overlap (430-648:162-373)
400 410 420 430 440 450
pF1KB8 KRRPLFRSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPS
: . ... : .. ..:. :: :. :.
NP_001 PGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLP-AIGTGNL-PEHWTDMN-H
140 150 160 170 180
460 470 480 490 500 510
pF1KB8 QDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMF
: : .: . .. : : . : .: .: : .: :.:: :::..:. ::. :. :
NP_001 QLFCMVQLEPGQSEYNTIKDKFTRTCS--SYAIEKIERIQNAFLWQSYQVKKRQMDIK--
190 200 210 220 230 240
520 530 540 550 560 570
pF1KB8 GRDRIINERHLFHGTSQDVVDGICKHNFDPRVC-GKHATMFGQGSYFAKKASYS--HNFS
:. ::: :::::. : : . .:.:. : : ::.:. .:.:.::: :::: ..:
NP_001 -NDHKNNERLLFHGTDADSVPYVNQHGFN-RSCAGKNAVSYGKGTYFAVDASYSAKDTYS
250 260 270 280 290 300
580 590 600 610 620 630
pF1KB8 KKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFN
: .:.: . :....:::: .: : :. ::: :: . : ::.:: ..: :..::.:
NP_001 KPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPT-DLFDSVTNNTRSPKLFVVFF
310 320 330 340 350 360
640 650
pF1KB8 DDQSYPYFVIQYEEVSNTVSI
:.:.:: ..: .
NP_001 DNQAYPEYLITFTA
370
>>XP_011510779 (OMIM: 612066) PREDICTED: poly [ADP-ribos (552 aa)
initn: 431 init1: 159 opt: 486 Z-score: 519.6 bits: 106.2 E(85289): 3.3e-22
Smith-Waterman score: 486; 41.1% identity (66.5% similar) in 209 aa overlap (443-648:351-550)
420 430 440 450 460 470
pF1KB8 PYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDK
.:. :. :: :. :. : : .: . ..
XP_011 IFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNL-PEHWTDMN-HQLFCMVQLEPGQS
330 340 350 360 370
480 490 500 510 520 530
pF1KB8 SYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMFGRDRIINERHLFH
: : . : .: .: : .: :.:: :::..:. ::. :. : :. ::: :::
XP_011 EYNTIKDKFTRTCS--SYAIEKIERIQNAFLWQSYQVKKRQMDIK---NDHKNNERLLFH
380 390 400 410 420 430
540 550 560 570 580
pF1KB8 GTSQDVVDGICKHNFDPRVC-GKHATMFGQGSYFAKKASYS--HNFSKKSSKGVHFMFLA
::. : : . .:.:. : : ::.:. .:.:.::: :::: ..:: .:.: . :...
XP_011 GTDADSVPYVNQHGFN-RSCAGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVV
440 450 460 470 480 490
590 600 610 620 630 640
pF1KB8 KVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYE
.:::: .: : :. ::: :: . : ::.:: ..: :..::.: :.:.:: ..: .
XP_011 RVLTGVFTKGRAGLVTPPPKNPHNPT-DLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT
500 510 520 530 540 550
650
pF1KB8 EVSNTVSI
XP_011 A
657 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:26:45 2016 done: Fri Nov 4 14:26:47 2016
Total Scan time: 11.400 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]