FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8675, 622 aa 1>>>pF1KB8675 622 - 622 aa - 622 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8198+/-0.000349; mu= 7.7518+/- 0.022 mean_var=148.2801+/-29.313, 0's: 0 Z-trim(118.5): 26 B-trim: 0 in 0/55 Lambda= 0.105325 statistics sampled from 31466 (31492) to 31466 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.369), width: 16 Scan time: 9.640 The best scores are: opt bits E(85289) NP_001305663 (OMIM: 609541,611729) kinesin light c ( 622) 4064 629.5 1e-179 NP_073733 (OMIM: 609541,611729) kinesin light chai ( 622) 4064 629.5 1e-179 XP_005274240 (OMIM: 609541,611729) PREDICTED: kine ( 622) 4064 629.5 1e-179 NP_001128247 (OMIM: 609541,611729) kinesin light c ( 622) 4064 629.5 1e-179 NP_001128248 (OMIM: 609541,611729) kinesin light c ( 622) 4064 629.5 1e-179 XP_005274241 (OMIM: 609541,611729) PREDICTED: kine ( 600) 3905 605.4 1.8e-172 NP_001128246 (OMIM: 609541,611729) kinesin light c ( 545) 3107 484.1 5.4e-136 NP_001123579 (OMIM: 600025) kinesin light chain 1 ( 618) 2604 407.7 6.1e-113 XP_016873622 (OMIM: 609541,611729) PREDICTED: kine ( 425) 2440 382.7 1.4e-105 NP_891553 (OMIM: 600025) kinesin light chain 1 iso ( 573) 2428 380.9 6.5e-105 NP_005543 (OMIM: 600025) kinesin light chain 1 iso ( 560) 2419 379.6 1.6e-104 NP_803136 (OMIM: 601334) kinesin light chain 3 [Ho ( 504) 1654 263.3 1.5e-69 NP_694972 (OMIM: 208540,267010,604387,608002) neph (1330) 440 79.1 1.1e-13 >>NP_001305663 (OMIM: 609541,611729) kinesin light chain (622 aa) initn: 4064 init1: 4064 opt: 4064 Z-score: 3347.5 bits: 629.5 E(85289): 1e-179 Smith-Waterman score: 4064; 99.8% identity (100.0% similar) in 622 aa overlap (1-622:1-622) 10 20 30 40 50 60 pF1KB8 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 AEPLCKRALEIREKVLGKFRPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_001 AEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG 550 560 570 580 590 600 610 620 pF1KB8 LSDSRTLSSSSMDLSRRSSLVG :::::::::::::::::::::: NP_001 LSDSRTLSSSSMDLSRRSSLVG 610 620 >>NP_073733 (OMIM: 609541,611729) kinesin light chain 2 (622 aa) initn: 4064 init1: 4064 opt: 4064 Z-score: 3347.5 bits: 629.5 E(85289): 1e-179 Smith-Waterman score: 4064; 99.8% identity (100.0% similar) in 622 aa overlap (1-622:1-622) 10 20 30 40 50 60 pF1KB8 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 AEPLCKRALEIREKVLGKFRPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_073 AEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG 550 560 570 580 590 600 610 620 pF1KB8 LSDSRTLSSSSMDLSRRSSLVG :::::::::::::::::::::: NP_073 LSDSRTLSSSSMDLSRRSSLVG 610 620 >>XP_005274240 (OMIM: 609541,611729) PREDICTED: kinesin (622 aa) initn: 4064 init1: 4064 opt: 4064 Z-score: 3347.5 bits: 629.5 E(85289): 1e-179 Smith-Waterman score: 4064; 99.8% identity (100.0% similar) in 622 aa overlap (1-622:1-622) 10 20 30 40 50 60 pF1KB8 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 AEPLCKRALEIREKVLGKFRPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_005 AEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG 550 560 570 580 590 600 610 620 pF1KB8 LSDSRTLSSSSMDLSRRSSLVG :::::::::::::::::::::: XP_005 LSDSRTLSSSSMDLSRRSSLVG 610 620 >>NP_001128247 (OMIM: 609541,611729) kinesin light chain (622 aa) initn: 4064 init1: 4064 opt: 4064 Z-score: 3347.5 bits: 629.5 E(85289): 1e-179 Smith-Waterman score: 4064; 99.8% identity (100.0% similar) in 622 aa overlap (1-622:1-622) 10 20 30 40 50 60 pF1KB8 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 AEPLCKRALEIREKVLGKFRPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_001 AEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG 550 560 570 580 590 600 610 620 pF1KB8 LSDSRTLSSSSMDLSRRSSLVG :::::::::::::::::::::: NP_001 LSDSRTLSSSSMDLSRRSSLVG 610 620 >>NP_001128248 (OMIM: 609541,611729) kinesin light chain (622 aa) initn: 4064 init1: 4064 opt: 4064 Z-score: 3347.5 bits: 629.5 E(85289): 1e-179 Smith-Waterman score: 4064; 99.8% identity (100.0% similar) in 622 aa overlap (1-622:1-622) 10 20 30 40 50 60 pF1KB8 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 AEPLCKRALEIREKVLGKFRPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_001 AEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG 550 560 570 580 590 600 610 620 pF1KB8 LSDSRTLSSSSMDLSRRSSLVG :::::::::::::::::::::: NP_001 LSDSRTLSSSSMDLSRRSSLVG 610 620 >>XP_005274241 (OMIM: 609541,611729) PREDICTED: kinesin (600 aa) initn: 4224 init1: 3905 opt: 3905 Z-score: 3217.2 bits: 605.4 E(85289): 1.8e-172 Smith-Waterman score: 3905; 99.7% identity (99.8% similar) in 597 aa overlap (1-597:1-597) 10 20 30 40 50 60 pF1KB8 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 AEPLCKRALEIREKVLGKFRPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_005 AEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG ::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_005 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQQGPLP 550 560 570 580 590 600 610 620 pF1KB8 LSDSRTLSSSSMDLSRRSSLVG >>NP_001128246 (OMIM: 609541,611729) kinesin light chain (545 aa) initn: 3104 init1: 3104 opt: 3107 Z-score: 2562.5 bits: 484.1 E(85289): 5.4e-136 Smith-Waterman score: 3420; 87.5% identity (87.6% similar) in 622 aa overlap (1-622:1-545) 10 20 30 40 50 60 pF1KB8 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL :::::::::::::::: NP_001 LRRSLEAIELGLGEAQ-------------------------------------------- 70 130 140 150 160 170 180 pF1KB8 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP ::::::::::::::::::::::::::: NP_001 ---------------------------------EEKGDVPKDTLDDLFPNEDEQSPAPSP 80 90 100 190 200 210 220 230 240 pF1KB8 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 110 120 130 140 150 160 250 260 270 280 290 300 pF1KB8 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 170 180 190 200 210 220 310 320 330 340 350 360 pF1KB8 AEPLCKRALEIREKVLGKFRPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_001 AEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP 230 240 250 260 270 280 370 380 390 400 410 420 pF1KB8 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 290 300 310 320 330 340 430 440 450 460 470 480 pF1KB8 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK 350 360 370 380 390 400 490 500 510 520 530 540 pF1KB8 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL 410 420 430 440 450 460 550 560 570 580 590 600 pF1KB8 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG 470 480 490 500 510 520 610 620 pF1KB8 LSDSRTLSSSSMDLSRRSSLVG :::::::::::::::::::::: NP_001 LSDSRTLSSSSMDLSRRSSLVG 530 540 >>NP_001123579 (OMIM: 600025) kinesin light chain 1 isof (618 aa) initn: 2547 init1: 1768 opt: 2604 Z-score: 2148.6 bits: 407.7 E(85289): 6.1e-113 Smith-Waterman score: 2615; 69.0% identity (85.1% similar) in 606 aa overlap (1-589:5-607) 10 20 30 40 pF1KB8 MAMMVFPRE---EKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAP----EAGE :. ::. .: :::.::::. :: ::::::.:..:: ..: :. . . NP_001 MYDNMSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 AEPGSQERCILLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWL .:. ..:.::: .::::.::::..:::.::.:::::::::::::::: :::::: NP_001 ESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 REELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKG-DVPKDTLDDLF :.:::.::::::.:::.::::::::.:: ::.:..: :.: ::.:.: : :. ::::: NP_001 RDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLF 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 PNEDEQSPAPS----PGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQA :: ::..:. . ... ...:.::::::::::::::::::::::::::::::::::: NP_001 PN-DEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQA 190 200 210 220 230 230 240 250 260 270 280 pF1KB8 LEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAAT :::::::::::::::::::::::::::::::::.::.::::::::::::::::::::::: NP_001 LEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAAT 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 LNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFRPDVAKQLSNLALLCQNQGKAEEVE :::::::::::::::::::::::::::::::::: .:::::::.::::::::::: :::: NP_001 LNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVE 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB8 YYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSV :::.:::::: :.::::::::::::::::::::::::...::::::::::::::.::::: NP_001 YYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSV 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB8 NGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGK . .::::::::::::: : :..:.. .::::.::::::::::::.:::..:::::::::: NP_001 DDENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGK 420 430 440 450 460 470 470 480 490 500 510 520 pF1KB8 LEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDL- .:::.:::. : :.:::::: . . .:.:.:.: . ..: ::. . . :: NP_001 FEAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENM--EKRRSRESLNVDVVKYESGPD 480 490 500 510 520 530 530 540 550 560 570 pF1KB8 --EDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQE--PPNPRMKR :.:. ..::::::.:::.:::::.::: ..::::: ::.::.::. .: : :: . NP_001 GGEEVSMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSSRESEPKNPGASL 540 550 560 570 580 590 580 590 600 610 620 pF1KB8 ASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRSSLVG : : : : NP_001 AEPLFVENDSSSSGLEDATAN 600 610 >>XP_016873622 (OMIM: 609541,611729) PREDICTED: kinesin (425 aa) initn: 2440 init1: 2440 opt: 2440 Z-score: 2016.3 bits: 382.7 E(85289): 1.4e-105 Smith-Waterman score: 2440; 99.5% identity (100.0% similar) in 372 aa overlap (251-622:54-425) 230 240 250 260 270 280 pF1KB8 CKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPA .::::::::::::::::::::::::::::: XP_016 VRKLPTALGAWRAGAEQVSPHSGSHSVIHTQDQNKYKEAAHLLNDALAIREKTLGKDHPA 30 40 50 60 70 80 290 300 310 320 330 340 pF1KB8 VAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFRPDVAKQLSNLALLCQNQGKA :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: XP_016 VAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKA 90 100 110 120 130 140 350 360 370 380 390 400 pF1KB8 EEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKE 150 160 170 180 190 200 410 420 430 440 450 460 pF1KB8 FGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYR 210 220 230 240 250 260 470 480 490 500 510 520 pF1KB8 RQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSE 270 280 290 300 310 320 530 540 550 560 570 580 pF1KB8 SDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRA 330 340 350 360 370 380 590 600 610 620 pF1KB8 SSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRSSLVG :::::::::::::::::::::::::::::::::::::::::: XP_016 SSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRSSLVG 390 400 410 420 >>NP_891553 (OMIM: 600025) kinesin light chain 1 isoform (573 aa) initn: 2747 init1: 1759 opt: 2428 Z-score: 2004.5 bits: 380.9 E(85289): 6.5e-105 Smith-Waterman score: 2439; 69.4% identity (85.4% similar) in 563 aa overlap (1-548:5-561) 10 20 30 40 pF1KB8 MAMMVFPRE---EKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAP----EAGE :. ::. .: :::.::::. :: ::::::.:..:: ..: :. . . NP_891 MYDNMSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 AEPGSQERCILLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWL .:. ..:.::: .::::.::::..:::.::.:::::::::::::::: :::::: NP_891 ESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 REELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKG-DVPKDTLDDLF :.:::.::::::.:::.::::::::.:: ::.:..: :.: ::.:.: : :. ::::: NP_891 RDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLF 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 PNEDEQSPAPS----PGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQA :: ::..:. . ... ...:.::::::::::::::::::::::::::::::::::: NP_891 PN-DEDDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQA 190 200 210 220 230 230 240 250 260 270 280 pF1KB8 LEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAAT :::::::::::::::::::::::::::::::::.::.::::::::::::::::::::::: NP_891 LEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAAT 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 LNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFRPDVAKQLSNLALLCQNQGKAEEVE :::::::::::::::::::::::::::::::::: .:::::::.::::::::::: :::: NP_891 LNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVE 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB8 YYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSV :::.:::::: :.::::::::::::::::::::::::...::::::::::::::.::::: NP_891 YYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSV 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB8 NGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGK . .::::::::::::: : :..:.. .::::.::::::::::::.:::..:::::::::: NP_891 DDENKPIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGK 420 430 440 450 460 470 470 480 490 500 510 520 pF1KB8 LEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDL- .:::.:::. : :.:::::: . . .:.:.:.: . ..: ::. . . :: NP_891 FEAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENM--EKRRSRESLNVDVVKYESGPD 480 490 500 510 520 530 530 540 550 560 570 580 pF1KB8 --EDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRAS :.:. ..:::: :: :.. :: NP_891 GGEEVSMSVEWNGGVSG---RASFCGKRQQQQWPGRRHR 540 550 560 570 622 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:28:43 2016 done: Fri Nov 4 14:28:44 2016 Total Scan time: 9.640 Total Display time: 0.150 Function used was FASTA [36.3.4 Apr, 2011]