FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8678, 376 aa 1>>>pF1KB8678 376 - 376 aa - 376 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3288+/-0.000461; mu= 16.0092+/- 0.029 mean_var=62.4163+/-12.348, 0's: 0 Z-trim(109.0): 39 B-trim: 60 in 1/49 Lambda= 0.162340 statistics sampled from 17154 (17192) to 17154 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.565), E-opt: 0.2 (0.202), width: 16 Scan time: 7.290 The best scores are: opt bits E(85289) NP_005727 (OMIM: 605143) alpha-centractin [Homo sa ( 376) 2488 591.8 8.5e-169 NP_005726 (OMIM: 605144) beta-centractin [Homo sap ( 376) 2344 558.1 1.2e-158 XP_016858605 (OMIM: 605144) PREDICTED: beta-centra ( 332) 2035 485.7 6.6e-137 XP_005263911 (OMIM: 605144) PREDICTED: beta-centra ( 302) 1847 441.6 1.1e-123 NP_005150 (OMIM: 102540,612098,612794,613424) acti ( 377) 1429 343.8 3.9e-94 NP_001186883 (OMIM: 102560,604717,614583) actin, c ( 375) 1427 343.3 5.4e-94 NP_001605 (OMIM: 102560,604717,614583) actin, cyto ( 375) 1427 343.3 5.4e-94 NP_001092 (OMIM: 102630,243310,607371,608578) acti ( 375) 1426 343.1 6.3e-94 NP_001091 (OMIM: 102610,161800,255310,616852) acti ( 377) 1424 342.6 8.8e-94 NP_001135417 (OMIM: 102620,611788,613834,614042) a ( 377) 1421 341.9 1.4e-93 NP_001307784 (OMIM: 102620,611788,613834,614042) a ( 377) 1421 341.9 1.4e-93 NP_001604 (OMIM: 102620,611788,613834,614042) acti ( 377) 1421 341.9 1.4e-93 NP_001606 (OMIM: 102545) actin, gamma-enteric smoo ( 376) 1418 341.2 2.3e-93 NP_001017992 (OMIM: 614835) beta-actin-like protei ( 376) 1399 336.8 5.1e-92 XP_016859649 (OMIM: 608914) PREDICTED: POTE ankyri ( 657) 1358 327.3 6.4e-89 XP_011509518 (OMIM: 608914) PREDICTED: POTE ankyri ( 957) 1358 327.3 8.9e-89 XP_016859648 (OMIM: 608914) PREDICTED: POTE ankyri ( 967) 1358 327.3 9e-89 NP_001077007 (OMIM: 608914) POTE ankyrin domain fa (1075) 1358 327.4 9.8e-89 XP_016859650 (OMIM: 608914) PREDICTED: POTE ankyri (1075) 1358 327.4 9.8e-89 NP_001186822 (OMIM: 102545) actin, gamma-enteric s ( 333) 1102 267.2 4e-71 NP_115876 (OMIM: 608534) actin-related protein T3 ( 372) 1065 258.5 1.8e-68 NP_536356 (OMIM: 608535) actin-related protein T2 ( 377) 1036 251.7 2e-66 NP_005713 (OMIM: 604221) actin-related protein 2 i ( 394) 1001 243.6 6.1e-64 NP_612146 (OMIM: 300487) actin-related protein T1 ( 376) 999 243.1 8.1e-64 NP_001005386 (OMIM: 604221) actin-related protein ( 399) 990 241.0 3.7e-63 NP_006678 (OMIM: 604303) actin-like protein 7A [Ho ( 435) 922 225.1 2.5e-58 NP_006677 (OMIM: 604304) actin-like protein 7B [Ho ( 415) 897 219.2 1.4e-56 NP_005712 (OMIM: 604222) actin-related protein 3 i ( 418) 501 126.5 1.1e-28 NP_001264069 (OMIM: 604222) actin-related protein ( 367) 482 122.0 2.2e-27 NP_057272 (OMIM: 612458) actin-like protein 6B [Ho ( 426) 410 105.2 3e-22 NP_817126 (OMIM: 604958) actin-like protein 6A iso ( 387) 337 88.0 3.9e-17 NP_829888 (OMIM: 604958) actin-like protein 6A iso ( 387) 337 88.0 3.9e-17 NP_004292 (OMIM: 604958) actin-like protein 6A iso ( 429) 337 88.1 4.3e-17 >>NP_005727 (OMIM: 605143) alpha-centractin [Homo sapien (376 aa) initn: 2488 init1: 2488 opt: 2488 Z-score: 3151.4 bits: 591.8 E(85289): 8.5e-169 Smith-Waterman score: 2488; 100.0% identity (100.0% similar) in 376 aa overlap (1-376:1-376) 10 20 30 40 50 60 pF1KB8 MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 MRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 YYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 YYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 SGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSK 310 320 330 340 350 360 370 pF1KB8 KEYEEDGARSIHRKTF :::::::::::::::: NP_005 KEYEEDGARSIHRKTF 370 >>NP_005726 (OMIM: 605144) beta-centractin [Homo sapiens (376 aa) initn: 2344 init1: 2344 opt: 2344 Z-score: 2969.2 bits: 558.1 E(85289): 1.2e-158 Smith-Waterman score: 2344; 90.4% identity (98.9% similar) in 376 aa overlap (1-376:1-376) 10 20 30 40 50 60 pF1KB8 MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGP :::::.::::::::::::::::::::::::::::::::::::::.::::::::::.:::: NP_005 MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKN :::::::::.::::::::.:.:::::::::::::::::::::::::::::::::::: :: NP_005 KAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI ::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 REKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 MRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQ ::.:::::::::.::: ::::: :::.:.:::.:..::::::::::::::::.:::::.: NP_005 MRVDIAGRDVSRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALETEKVQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 YYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVL : ::::::...::.:::::::::.:::.:.::::.:::..:::.:::::::::::.:::: NP_005 YTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 SGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSK :::::::::::::::::::::::::.::.::::::::::::::::::::::::::::::: NP_005 SGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKKMWVSK 310 320 330 340 350 360 370 pF1KB8 KEYEEDGARSIHRKTF :::::::.:.:::::: NP_005 KEYEEDGSRAIHRKTF 370 >>XP_016858605 (OMIM: 605144) PREDICTED: beta-centractin (332 aa) initn: 2035 init1: 2035 opt: 2035 Z-score: 2578.9 bits: 485.7 E(85289): 6.6e-137 Smith-Waterman score: 2035; 89.5% identity (98.8% similar) in 332 aa overlap (45-376:1-332) 20 30 40 50 60 70 pF1KB8 DNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYP .::::::::::.:::::::::::::.:::: XP_016 MRVMAGALEGDLFIGPKAEEHRGLLTIRYP 10 20 30 80 90 100 110 120 130 pF1KB8 MEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNV ::::.:.:::::::::::::::::::::::::::::::::::: ::::.::::::::::: XP_016 MEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNV 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB8 PALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFL ::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::.: XP_016 PALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYL 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB8 RLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPS :: ::::: :::.:.:::.:..::::::::::::::::.:::::.:: ::::::...::. XP_016 RLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALETEKVQYTLPDGSTLDVGPA 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB8 RFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRL :::::::::.:::.:.::::.:::..:::.:::::::::::.:::::::::::::::::: XP_016 RFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVLSGGSTLFKGFGDRL 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB8 LSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRK :::::::::::.::.::::::::::::::::::::::::::::::::::::::.:.:::: XP_016 LSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRK 280 290 300 310 320 330 pF1KB8 TF :: XP_016 TF >>XP_005263911 (OMIM: 605144) PREDICTED: beta-centractin (302 aa) initn: 1847 init1: 1847 opt: 1847 Z-score: 2341.6 bits: 441.6 E(85289): 1.1e-123 Smith-Waterman score: 1847; 89.4% identity (98.7% similar) in 302 aa overlap (75-376:1-302) 50 60 70 80 90 100 pF1KB8 VRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSE ::::.:.::::::::::::::::::::::: XP_005 MEHGVVRDWNDMERIWQYVYSKDQLQTFSE 10 20 30 110 120 130 140 150 160 pF1KB8 EHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGV ::::::::::::: ::::.::::::::::::::::::::::::::::::::::::::::: XP_005 EHPVLLTEAPLNPSKNREKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGV 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB8 THAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYL ::::::::::::::::::.:::::::::.::: ::::: :::.:.:::.:..:::::::: XP_005 THAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYL 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB8 SINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQ ::::::::.:::::.:: ::::::...::.:::::::::.:::.:.::::.:::..:::. XP_005 SINPQKDEALETEKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIH 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB8 KSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGG :::::::::::.:::::::::::::::::::::::::::::.::.::::::::::::::: XP_005 KSDMDLRRTLFANIVLSGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGG 220 230 240 250 260 270 350 360 370 pF1KB8 SILASLDTFKKMWVSKKEYEEDGARSIHRKTF :::::::::::::::::::::::.:.:::::: XP_005 SILASLDTFKKMWVSKKEYEEDGSRAIHRKTF 280 290 300 >>NP_005150 (OMIM: 102540,612098,612794,613424) actin, a (377 aa) initn: 1421 init1: 571 opt: 1429 Z-score: 1811.0 bits: 343.8 E(85289): 3.9e-94 Smith-Waterman score: 1429; 53.7% identity (82.1% similar) in 369 aa overlap (12-376:10-377) 10 20 30 40 50 60 pF1KB8 MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGP .: :::::..:::::::. :. ::. ::::.: ::.: . : ..: NP_005 MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 KAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKN .:. .::.:...::.::::. .:.:::.::.... ..:.. ::::.:::::::::. : NP_005 EAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFY-NELRVAPEEHPTLLTEAPLNPKAN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 RERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI ::. ....::::::::.....::::::::.:::::.:::::::::: ::::::.:.::.: NP_005 REKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 MRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQ ::.:.::::.. .: : ..::.: ...: :::. :::. ::.... ... . . ... NP_005 MRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSS 180 190 200 210 220 230 250 260 270 280 290 pF1KB8 ----YYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFS : ::::..: :: ::: :: ::.:..:: :: ::::. .:.: :.:.:. :.. NP_005 LEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYA 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 NIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKM : :::::.:.. :..::. .:. :::. .::.: :: :: ::.::::::::::.::..: NP_005 NNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQM 300 310 320 330 340 350 360 370 pF1KB8 WVSKKEYEEDGARSIHRKTF :.::.::.: : .::: : NP_005 WISKQEYDEAGPSIVHRKCF 360 370 >>NP_001186883 (OMIM: 102560,604717,614583) actin, cytop (375 aa) initn: 1422 init1: 570 opt: 1427 Z-score: 1808.5 bits: 343.3 E(85289): 5.4e-94 Smith-Waterman score: 1427; 53.4% identity (82.7% similar) in 369 aa overlap (12-376:8-375) 10 20 30 40 50 60 pF1KB8 MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGP .:::::::. :::::::. :. ::. ::::.: ::.: . : ..: NP_001 MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 KAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKN .:. .::.:...::.::::: .:.:::.::.... ..:.. ::::::::::::::. : NP_001 EAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFY-NELRVAPEEHPVLLTEAPLNPKAN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 RERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI ::. ....:::::.::.....::::::::.:::::.:.::::::::.::::::.:.::.: NP_001 REKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 MRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQ .:.:.::::.. .: : ..::.: ...: :::. :::. ::.... ... . . ... NP_001 LRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSS 180 190 200 210 220 230 250 260 270 280 290 pF1KB8 ----YYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFS : ::::..: :: ::: :: ::.:...: :: ::::. .:.: :.:.:. :.. NP_001 LEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYA 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 NIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKM : :::::.:.. :..::. .:. :::. .::.: :: :: ::.::::::::::.::..: NP_001 NTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQM 300 310 320 330 340 350 360 370 pF1KB8 WVSKKEYEEDGARSIHRKTF :.::.::.:.: .::: : NP_001 WISKQEYDESGPSIVHRKCF 360 370 >>NP_001605 (OMIM: 102560,604717,614583) actin, cytoplas (375 aa) initn: 1422 init1: 570 opt: 1427 Z-score: 1808.5 bits: 343.3 E(85289): 5.4e-94 Smith-Waterman score: 1427; 53.4% identity (82.7% similar) in 369 aa overlap (12-376:8-375) 10 20 30 40 50 60 pF1KB8 MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGP .:::::::. :::::::. :. ::. ::::.: ::.: . : ..: NP_001 MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 KAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKN .:. .::.:...::.::::: .:.:::.::.... ..:.. ::::::::::::::. : NP_001 EAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFY-NELRVAPEEHPVLLTEAPLNPKAN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 RERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI ::. ....:::::.::.....::::::::.:::::.:.::::::::.::::::.:.::.: NP_001 REKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 MRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQ .:.:.::::.. .: : ..::.: ...: :::. :::. ::.... ... . . ... NP_001 LRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSS 180 190 200 210 220 230 250 260 270 280 290 pF1KB8 ----YYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFS : ::::..: :: ::: :: ::.:...: :: ::::. .:.: :.:.:. :.. NP_001 LEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYA 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 NIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKM : :::::.:.. :..::. .:. :::. .::.: :: :: ::.::::::::::.::..: NP_001 NTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQM 300 310 320 330 340 350 360 370 pF1KB8 WVSKKEYEEDGARSIHRKTF :.::.::.:.: .::: : NP_001 WISKQEYDESGPSIVHRKCF 360 370 >>NP_001092 (OMIM: 102630,243310,607371,608578) actin, c (375 aa) initn: 1412 init1: 570 opt: 1426 Z-score: 1807.2 bits: 343.1 E(85289): 6.3e-94 Smith-Waterman score: 1426; 53.1% identity (82.7% similar) in 369 aa overlap (12-376:8-375) 10 20 30 40 50 60 pF1KB8 MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGP .:.:::::. :::::::. :. ::. ::::.: ::.: . : ..: NP_001 MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 KAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKN .:. .::.:...::.::::: .:.:::.::.... ..:.. ::::::::::::::. : NP_001 EAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFY-NELRVAPEEHPVLLTEAPLNPKAN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 RERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI ::. ....:::::.::.....::::::::.:::::.:.::::::::.::::::.:.::.: NP_001 REKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 MRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQ .:.:.::::.. .: : ..::.: ...: :::. :::. ::.... ... . . ... NP_001 LRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSS 180 190 200 210 220 230 250 260 270 280 290 pF1KB8 ----YYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFS : ::::..: :: ::: :: ::.:...: :: ::::. .:.: :.:.:. :.. NP_001 LEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYA 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 NIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKM : :::::.:.. :..::. .:. :::. .::.: :: :: ::.::::::::::.::..: NP_001 NTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQM 300 310 320 330 340 350 360 370 pF1KB8 WVSKKEYEEDGARSIHRKTF :.::.::.:.: .::: : NP_001 WISKQEYDESGPSIVHRKCF 360 370 >>NP_001091 (OMIM: 102610,161800,255310,616852) actin, a (377 aa) initn: 1416 init1: 571 opt: 1424 Z-score: 1804.7 bits: 342.6 E(85289): 8.8e-94 Smith-Waterman score: 1424; 53.1% identity (82.1% similar) in 369 aa overlap (12-376:10-377) 10 20 30 40 50 60 pF1KB8 MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGP .: :::::..:::::::. :. ::. ::::.: ::.: . : ..: NP_001 MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 KAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKN .:. .::.:...::.::::. .:.:::.::.... ..:.. ::::.:::::::::. : NP_001 EAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFY-NELRVAPEEHPTLLTEAPLNPKAN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 RERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI ::. ....::::::::.....::::::::.:::::.:::::::::: ::::::.:.::.: NP_001 REKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 MRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQ ::.:.::::.. .: : ..::.: ...: :::. :::. ::.... ... . . ... NP_001 MRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSS 180 190 200 210 220 230 250 260 270 280 290 pF1KB8 ----YYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFS : ::::..: :: ::: :: ::.:..:: :: ::::. .:.: :.:.:. :.. NP_001 LEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYA 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 NIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKM : :.:::.:.. :..::. .:. :::. .::.: :: :: ::.::::::::::.::..: NP_001 NNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQM 300 310 320 330 340 350 360 370 pF1KB8 WVSKKEYEEDGARSIHRKTF :..:.::.: : .::: : NP_001 WITKQEYDEAGPSIVHRKCF 360 370 >>NP_001135417 (OMIM: 102620,611788,613834,614042) actin (377 aa) initn: 1413 init1: 571 opt: 1421 Z-score: 1800.9 bits: 341.9 E(85289): 1.4e-93 Smith-Waterman score: 1421; 53.7% identity (81.6% similar) in 369 aa overlap (12-376:10-377) 10 20 30 40 50 60 pF1KB8 MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGP .: :::::. :::::::. :. ::. ::::.: ::.: . : ..: NP_001 MCEEEDSTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 KAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKN .:. .::.:...::.::::. .:.:::.::.. . ..:.. ::::.:::::::::. : NP_001 EAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFY-NELRVAPEEHPTLLTEAPLNPKAN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 RERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI ::. ....::::::::.....::::::::.:::::.:::::::::: ::::::.:.::.: NP_001 REKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 MRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQ ::.:.::::.. .: : ..::.: ...: :::. :::. ::.... ... . . ... NP_001 MRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSS 180 190 200 210 220 230 250 260 270 280 290 pF1KB8 ----YYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFS : ::::..: :: ::: :: ::.:..:: :: ::::. .:.: :.:.:. :.. NP_001 LEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYA 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 NIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKM : :::::.:.. :..::. .:. :::. .::.: :: :: ::.::::::::::.::..: NP_001 NNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQM 300 310 320 330 340 350 360 370 pF1KB8 WVSKKEYEEDGARSIHRKTF :.::.::.: : .::: : NP_001 WISKQEYDEAGPSIVHRKCF 360 370 376 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:30:44 2016 done: Fri Nov 4 14:30:45 2016 Total Scan time: 7.290 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]