FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8679, 514 aa 1>>>pF1KB8679 514 - 514 aa - 514 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5416+/-0.000388; mu= 13.4966+/- 0.024 mean_var=114.4480+/-22.553, 0's: 0 Z-trim(115.0): 55 B-trim: 611 in 1/55 Lambda= 0.119886 statistics sampled from 25126 (25178) to 25126 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.295), width: 16 Scan time: 8.850 The best scores are: opt bits E(85289) NP_001354 (OMIM: 300126,305000) H/ACA ribonucleopr ( 514) 3338 588.5 1.5e-167 NP_001135935 (OMIM: 300126,305000) H/ACA ribonucle ( 509) 3280 578.5 1.6e-164 NP_001275676 (OMIM: 300126,305000) H/ACA ribonucle ( 420) 2764 489.2 1e-137 >>NP_001354 (OMIM: 300126,305000) H/ACA ribonucleoprotei (514 aa) initn: 3338 init1: 3338 opt: 3338 Z-score: 3128.9 bits: 588.5 E(85289): 1.5e-167 Smith-Waterman score: 3338; 100.0% identity (100.0% similar) in 514 aa overlap (1-514:1-514) 10 20 30 40 50 60 pF1KB8 MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQEYVDYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQEYVDYS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 ESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAK 430 440 450 460 470 480 490 500 510 pF1KB8 AGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE :::::::::::::::::::::::::::::::::: NP_001 AGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE 490 500 510 >>NP_001135935 (OMIM: 300126,305000) H/ACA ribonucleopro (509 aa) initn: 3076 init1: 2741 opt: 3280 Z-score: 3074.8 bits: 578.5 E(85289): 1.6e-164 Smith-Waterman score: 3280; 98.8% identity (99.0% similar) in 514 aa overlap (1-514:1-509) 10 20 30 40 50 60 pF1KB8 MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQEYVDYS ::::::::::::::::::::::::::::::::::::::::::::::::::::::. NP_001 GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQD----- 370 380 390 400 410 430 440 450 460 470 480 pF1KB8 ESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAK 420 430 440 450 460 470 490 500 510 pF1KB8 AGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE :::::::::::::::::::::::::::::::::: NP_001 AGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE 480 490 500 >>NP_001275676 (OMIM: 300126,305000) H/ACA ribonucleopro (420 aa) initn: 2764 init1: 2764 opt: 2764 Z-score: 2593.6 bits: 489.2 E(85289): 1e-137 Smith-Waterman score: 2764; 100.0% identity (100.0% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KB8 MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQEYVDYS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQEYVDYR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 ESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAK 514 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:54:12 2016 done: Sat Nov 5 21:54:13 2016 Total Scan time: 8.850 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]