FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8683, 672 aa 1>>>pF1KB8683 672 - 672 aa - 672 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.9198+/-0.000482; mu= 7.4511+/- 0.030 mean_var=145.4565+/-29.730, 0's: 0 Z-trim(113.3): 77 B-trim: 0 in 0/50 Lambda= 0.106343 statistics sampled from 22456 (22533) to 22456 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.264), width: 16 Scan time: 11.730 The best scores are: opt bits E(85289) NP_113609 (OMIM: 617092,617095) tetratricopeptide ( 672) 4393 686.5 8.7e-197 XP_011523625 (OMIM: 617092,617095) PREDICTED: tetr ( 509) 3315 521.0 4.2e-147 XP_011523626 (OMIM: 617092,617095) PREDICTED: tetr ( 480) 2963 467.0 7.3e-131 NP_001269582 (OMIM: 605063) stress-induced-phospho ( 519) 207 44.2 0.0015 XP_011539605 (OMIM: 604213,609245) PREDICTED: G-pr ( 458) 193 42.0 0.0059 XP_006710652 (OMIM: 604213,609245) PREDICTED: G-pr ( 665) 193 42.1 0.0081 XP_016856587 (OMIM: 604213,609245) PREDICTED: G-pr ( 684) 193 42.1 0.0083 NP_001307968 (OMIM: 604213,609245) G-protein-signa ( 684) 193 42.1 0.0083 XP_011539603 (OMIM: 604213,609245) PREDICTED: G-pr ( 684) 193 42.1 0.0083 NP_001307967 (OMIM: 604213,609245) G-protein-signa ( 684) 193 42.1 0.0083 XP_011539604 (OMIM: 604213,609245) PREDICTED: G-pr ( 684) 193 42.1 0.0083 XP_016856586 (OMIM: 604213,609245) PREDICTED: G-pr ( 684) 193 42.1 0.0083 NP_037428 (OMIM: 604213,609245) G-protein-signalin ( 684) 193 42.1 0.0083 >>NP_113609 (OMIM: 617092,617095) tetratricopeptide repe (672 aa) initn: 4393 init1: 4393 opt: 4393 Z-score: 3653.9 bits: 686.5 E(85289): 8.7e-197 Smith-Waterman score: 4393; 100.0% identity (100.0% similar) in 672 aa overlap (1-672:1-672) 10 20 30 40 50 60 pF1KB8 MSDPEGETLRSTFPSYMAEGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 MSDPEGETLRSTFPSYMAEGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GDLERSLKDAEASLQSDPAFCKGILQKAETLYTMGDFEFALVFYHRGYKLRPDREFRVGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 GDLERSLKDAEASLQSDPAFCKGILQKAETLYTMGDFEFALVFYHRGYKLRPDREFRVGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QKAQEAINNSVGSPSSIKLENKGDLSFLSKQAENIKAQQKPQPMKHLLHPTKGEPKWKAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 QKAQEAINNSVGSPSSIKLENKGDLSFLSKQAENIKAQQKPQPMKHLLHPTKGEPKWKAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LKSEKTVRQLLGELYVDKEYLEKLLLDEDLIKGTMKGGLTVEDLIMTGINYLDTHSNFWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 LKSEKTVRQLLGELYVDKEYLEKLLLDEDLIKGTMKGGLTVEDLIMTGINYLDTHSNFWR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 QQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 QQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 LKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 RALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELDQAWQAQNYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 RALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELDQAWQAQNYG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 EKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQAII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 EKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQAII 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 SALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREKDMRRVRDEPEKVVKQWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 SALDDANKGIIRELRKTNYVENLKEKSEGEASLYEDRIITREKDMRRVRDEPEKVVKQWD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 HSEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVAKGLSGELGTRSGETGRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 HSEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVAKGLSGELGTRSGETGRKL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 LEAGRRESREIYRRPSGELEQRLSGEFSRQEPEELKKLSEVGRREPEELGKTQFGEIGET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 LEAGRRESREIYRRPSGELEQRLSGEFSRQEPEELKKLSEVGRREPEELGKTQFGEIGET 610 620 630 640 650 660 670 pF1KB8 KKTGNEMEKEYE :::::::::::: NP_113 KKTGNEMEKEYE 670 >>XP_011523625 (OMIM: 617092,617095) PREDICTED: tetratri (509 aa) initn: 3315 init1: 3315 opt: 3315 Z-score: 2761.9 bits: 521.0 E(85289): 4.2e-147 Smith-Waterman score: 3315; 100.0% identity (100.0% similar) in 509 aa overlap (164-672:1-509) 140 150 160 170 180 190 pF1KB8 PSSIKLENKGDLSFLSKQAENIKAQQKPQPMKHLLHPTKGEPKWKASLKSEKTVRQLLGE :::::::::::::::::::::::::::::: XP_011 MKHLLHPTKGEPKWKASLKSEKTVRQLLGE 10 20 30 200 210 220 230 240 250 pF1KB8 LYVDKEYLEKLLLDEDLIKGTMKGGLTVEDLIMTGINYLDTHSNFWRQQKPIYARERDRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYVDKEYLEKLLLDEDLIKGTMKGGLTVEDLIMTGINYLDTHSNFWRQQKPIYARERDRK 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB8 LMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKVLKKVLEWNKEEVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKVLKKVLEWNKEEVP 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB8 NKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDNIGRVFARV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDNIGRVFARV 160 170 180 190 200 210 380 390 400 410 420 430 pF1KB8 GKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELDQAWQAQNYGEKSQQCAEEEGDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELDQAWQAQNYGEKSQQCAEEEGDI 220 230 240 250 260 270 440 450 460 470 480 490 pF1KB8 EWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQAIISALDDANKGIIRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQAIISALDDANKGIIRE 280 290 300 310 320 330 500 510 520 530 540 550 pF1KB8 LRKTNYVENLKEKSEGEASLYEDRIITREKDMRRVRDEPEKVVKQWDHSEDEKETDEDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRKTNYVENLKEKSEGEASLYEDRIITREKDMRRVRDEPEKVVKQWDHSEDEKETDEDDE 340 350 360 370 380 390 560 570 580 590 600 610 pF1KB8 AFGEALQSPASGKQSVEAGKARSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFGEALQSPASGKQSVEAGKARSDLGAVAKGLSGELGTRSGETGRKLLEAGRRESREIYR 400 410 420 430 440 450 620 630 640 650 660 670 pF1KB8 RPSGELEQRLSGEFSRQEPEELKKLSEVGRREPEELGKTQFGEIGETKKTGNEMEKEYE ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPSGELEQRLSGEFSRQEPEELKKLSEVGRREPEELGKTQFGEIGETKKTGNEMEKEYE 460 470 480 490 500 >>XP_011523626 (OMIM: 617092,617095) PREDICTED: tetratri (480 aa) initn: 2963 init1: 2963 opt: 2963 Z-score: 2470.4 bits: 467.0 E(85289): 7.3e-131 Smith-Waterman score: 2963; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447) 10 20 30 40 50 60 pF1KB8 MSDPEGETLRSTFPSYMAEGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSDPEGETLRSTFPSYMAEGERLYLCGEFSKAAQSFSNALYLQDGDKNCLVARSKCFLKM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GDLERSLKDAEASLQSDPAFCKGILQKAETLYTMGDFEFALVFYHRGYKLRPDREFRVGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDLERSLKDAEASLQSDPAFCKGILQKAETLYTMGDFEFALVFYHRGYKLRPDREFRVGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QKAQEAINNSVGSPSSIKLENKGDLSFLSKQAENIKAQQKPQPMKHLLHPTKGEPKWKAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QKAQEAINNSVGSPSSIKLENKGDLSFLSKQAENIKAQQKPQPMKHLLHPTKGEPKWKAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LKSEKTVRQLLGELYVDKEYLEKLLLDEDLIKGTMKGGLTVEDLIMTGINYLDTHSNFWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKSEKTVRQLLGELYVDKEYLEKLLLDEDLIKGTMKGGLTVEDLIMTGINYLDTHSNFWR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 QQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQKPIYARERDRKLMQEKWLRDHKRRPSQTAHYILKSLEDIDMLLTSGSAEGSLQKAEKV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEIAKEYDLPDAKS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 RALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELDQAWQAQNYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELDQAWQAQNYG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 EKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQAII ::::::::::::::::::::::::::: XP_011 EKSQQCAEEEGDIEWQLNASVLVAQAQGLGRCQQGYHQRTEENQLRGESQRKKRGRSFTV 430 440 450 460 470 480 >>NP_001269582 (OMIM: 605063) stress-induced-phosphoprot (519 aa) initn: 119 init1: 89 opt: 207 Z-score: 184.8 bits: 44.2 E(85289): 0.0015 Smith-Waterman score: 207; 26.2% identity (56.9% similar) in 160 aa overlap (19-170:342-501) 10 20 30 40 pF1KB8 MSDPEGETLRSTFPSYMAEGERLYLCGEFSKAAQSFSNALYLQDGDKN .:.. . :.. .: . ...:. . : . NP_001 LKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAK 320 330 340 350 360 370 50 60 70 80 90 100 pF1KB8 CLVARSKCFLKMGDLERSLKDAEASLQSDPAFCKGILQKAETLYTMGDFEFALVFYHRGY :. :. :. ... .::: : .: .:.: :: .:: .: .: :. :. :... NP_001 LYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKAL 380 390 400 410 420 430 110 120 130 140 150 160 pF1KB8 KLRPD-REFRVGIQKAQEAINNSVGSPSSIKLENKGD---LSFLSKQAENI---KAQQKP : . .: : :. . : : :: ..: . .: ...: : . . :. : NP_001 DLDSSCKEAADGYQRCMMAQYNRHDSPEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDP 440 450 460 470 480 490 170 180 190 200 210 220 pF1KB8 QPM-KHLLHPTKGEPKWKASLKSEKTVRQLLGELYVDKEYLEKLLLDEDLIKGTMKGGLT : . .:: .: NP_001 QALSEHLKNPVIAQKIQKLMDVGLIAIR 500 510 >>XP_011539605 (OMIM: 604213,609245) PREDICTED: G-protei (458 aa) initn: 252 init1: 124 opt: 193 Z-score: 174.0 bits: 42.0 E(85289): 0.0059 Smith-Waterman score: 193; 23.6% identity (58.7% similar) in 225 aa overlap (320-537:202-424) 290 300 310 320 330 340 pF1KB8 AEGSLQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEI : .. .::.. ::... :. .:.. : : XP_011 EEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLI 180 190 200 210 220 230 350 360 370 380 390 400 pF1KB8 AKEYDLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKT---WLFHEIGRC :::. :. :: .:.: .. .:.:. : . ... . ::. ... . .: XP_011 AKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNT 240 250 260 270 280 290 410 420 430 440 450 460 pF1KB8 YLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALER : :.. .: .: : :.: .: . : ...: . : . ..:.. :: :: XP_011 YTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEI 300 310 320 330 340 350 470 480 490 500 510 520 pF1KB8 AKLVHNNEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEASL--YEDRIITRE-- .. : .. .. . . :. .. .. : .. ..:..: ..:: . .. :. XP_011 SREVGDKSGE--LTARLNLSDLQMVLGLSYSTNNSIMSENTEIDSSLNGVRPKLGRRHSM 360 370 380 390 400 530 540 550 560 570 580 pF1KB8 KDMRRVRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVA ..:. .. ::::.: XP_011 ENMELMKLTPEKVLKNQHFNVLIMRIHSMHLVQVLKIVQYTKKDIFKEI 410 420 430 440 450 >>XP_006710652 (OMIM: 604213,609245) PREDICTED: G-protei (665 aa) initn: 282 init1: 124 opt: 193 Z-score: 171.5 bits: 42.1 E(85289): 0.0081 Smith-Waterman score: 193; 23.2% identity (58.8% similar) in 228 aa overlap (320-540:183-407) 290 300 310 320 330 340 pF1KB8 AEGSLQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEI : .. .::.. ::... :. .:.. : : XP_006 EEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLI 160 170 180 190 200 210 350 360 370 380 390 400 pF1KB8 AKEYDLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKT---WLFHEIGRC :::. :. :: .:.: .. .:.:. : . ... . ::. ... . .: XP_006 AKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNT 220 230 240 250 260 270 410 420 430 440 450 460 pF1KB8 YLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALER : :.. .: .: : :.: .: . : ...: . : . ..:.. :: :: XP_006 YTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEI 280 290 300 310 320 330 470 480 490 500 510 520 pF1KB8 AKLVHNNEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEASL--YEDRIITRE-- .. : .. .. . . :. .. .. : .. ..:..: ..:: . .. :. XP_006 SREVGDKSGE--LTARLNLSDLQMVLGLSYSTNNSIMSENTEIDSSLNGVRPKLGRRHSM 340 350 360 370 380 390 530 540 550 560 570 580 pF1KB8 KDMRRVRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVA ..:. .. :::: ..:. XP_006 ENMELMKLTPEKV-QNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKTNSSTKVLQDAS 400 410 420 430 440 >>XP_016856587 (OMIM: 604213,609245) PREDICTED: G-protei (684 aa) initn: 282 init1: 124 opt: 193 Z-score: 171.4 bits: 42.1 E(85289): 0.0083 Smith-Waterman score: 193; 23.2% identity (58.8% similar) in 228 aa overlap (320-540:202-426) 290 300 310 320 330 340 pF1KB8 AEGSLQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEI : .. .::.. ::... :. .:.. : : XP_016 EEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLI 180 190 200 210 220 230 350 360 370 380 390 400 pF1KB8 AKEYDLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKT---WLFHEIGRC :::. :. :: .:.: .. .:.:. : . ... . ::. ... . .: XP_016 AKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNT 240 250 260 270 280 290 410 420 430 440 450 460 pF1KB8 YLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALER : :.. .: .: : :.: .: . : ...: . : . ..:.. :: :: XP_016 YTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEI 300 310 320 330 340 350 470 480 490 500 510 520 pF1KB8 AKLVHNNEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEASL--YEDRIITRE-- .. : .. .. . . :. .. .. : .. ..:..: ..:: . .. :. XP_016 SREVGDKSGE--LTARLNLSDLQMVLGLSYSTNNSIMSENTEIDSSLNGVRPKLGRRHSM 360 370 380 390 400 530 540 550 560 570 580 pF1KB8 KDMRRVRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVA ..:. .. :::: ..:. XP_016 ENMELMKLTPEKV-QNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKTNSSTKVLQDAS 410 420 430 440 450 460 >>NP_001307968 (OMIM: 604213,609245) G-protein-signaling (684 aa) initn: 282 init1: 124 opt: 193 Z-score: 171.4 bits: 42.1 E(85289): 0.0083 Smith-Waterman score: 193; 23.2% identity (58.8% similar) in 228 aa overlap (320-540:202-426) 290 300 310 320 330 340 pF1KB8 AEGSLQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEI : .. .::.. ::... :. .:.. : : NP_001 EEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLI 180 190 200 210 220 230 350 360 370 380 390 400 pF1KB8 AKEYDLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKT---WLFHEIGRC :::. :. :: .:.: .. .:.:. : . ... . ::. ... . .: NP_001 AKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNT 240 250 260 270 280 290 410 420 430 440 450 460 pF1KB8 YLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALER : :.. .: .: : :.: .: . : ...: . : . ..:.. :: :: NP_001 YTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEI 300 310 320 330 340 350 470 480 490 500 510 520 pF1KB8 AKLVHNNEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEASL--YEDRIITRE-- .. : .. .. . . :. .. .. : .. ..:..: ..:: . .. :. NP_001 SREVGDKSGE--LTARLNLSDLQMVLGLSYSTNNSIMSENTEIDSSLNGVRPKLGRRHSM 360 370 380 390 400 530 540 550 560 570 580 pF1KB8 KDMRRVRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVA ..:. .. :::: ..:. NP_001 ENMELMKLTPEKV-QNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKTNSSTKVLQDAS 410 420 430 440 450 460 >>XP_011539603 (OMIM: 604213,609245) PREDICTED: G-protei (684 aa) initn: 282 init1: 124 opt: 193 Z-score: 171.4 bits: 42.1 E(85289): 0.0083 Smith-Waterman score: 193; 23.2% identity (58.8% similar) in 228 aa overlap (320-540:202-426) 290 300 310 320 330 340 pF1KB8 AEGSLQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEI : .. .::.. ::... :. .:.. : : XP_011 EEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLI 180 190 200 210 220 230 350 360 370 380 390 400 pF1KB8 AKEYDLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKT---WLFHEIGRC :::. :. :: .:.: .. .:.:. : . ... . ::. ... . .: XP_011 AKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNT 240 250 260 270 280 290 410 420 430 440 450 460 pF1KB8 YLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALER : :.. .: .: : :.: .: . : ...: . : . ..:.. :: :: XP_011 YTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEI 300 310 320 330 340 350 470 480 490 500 510 520 pF1KB8 AKLVHNNEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEASL--YEDRIITRE-- .. : .. .. . . :. .. .. : .. ..:..: ..:: . .. :. XP_011 SREVGDKSGE--LTARLNLSDLQMVLGLSYSTNNSIMSENTEIDSSLNGVRPKLGRRHSM 360 370 380 390 400 530 540 550 560 570 580 pF1KB8 KDMRRVRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVA ..:. .. :::: ..:. XP_011 ENMELMKLTPEKV-QNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKTNSSTKVLQDAS 410 420 430 440 450 460 >>NP_001307967 (OMIM: 604213,609245) G-protein-signaling (684 aa) initn: 282 init1: 124 opt: 193 Z-score: 171.4 bits: 42.1 E(85289): 0.0083 Smith-Waterman score: 193; 23.2% identity (58.8% similar) in 228 aa overlap (320-540:202-426) 290 300 310 320 330 340 pF1KB8 AEGSLQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDLEI : .. .::.. ::... :. .:.. : : NP_001 EEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLI 180 190 200 210 220 230 350 360 370 380 390 400 pF1KB8 AKEYDLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKT---WLFHEIGRC :::. :. :: .:.: .. .:.:. : . ... . ::. ... . .: NP_001 AKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNT 240 250 260 270 280 290 410 420 430 440 450 460 pF1KB8 YLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFEKALER : :.. .: .: : :.: .: . : ...: . : . ..:.. :: :: NP_001 YTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEI 300 310 320 330 340 350 470 480 490 500 510 520 pF1KB8 AKLVHNNEAQQAIISALDDANKGIIRELRKTNYVENLKEKSEGEASL--YEDRIITRE-- .. : .. .. . . :. .. .. : .. ..:..: ..:: . .. :. NP_001 SREVGDKSGE--LTARLNLSDLQMVLGLSYSTNNSIMSENTEIDSSLNGVRPKLGRRHSM 360 370 380 390 400 530 540 550 560 570 580 pF1KB8 KDMRRVRDEPEKVVKQWDHSEDEKETDEDDEAFGEALQSPASGKQSVEAGKARSDLGAVA ..:. .. :::: ..:. NP_001 ENMELMKLTPEKV-QNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKTNSSTKVLQDAS 410 420 430 440 450 460 672 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:33:07 2016 done: Fri Nov 4 14:33:09 2016 Total Scan time: 11.730 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]