FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8685, 717 aa 1>>>pF1KB8685 717 - 717 aa - 717 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5102+/-0.00078; mu= 10.9514+/- 0.048 mean_var=138.2350+/-26.665, 0's: 0 Z-trim(113.1): 10 B-trim: 0 in 0/51 Lambda= 0.109085 statistics sampled from 13785 (13795) to 13785 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.748), E-opt: 0.2 (0.424), width: 16 Scan time: 3.290 The best scores are: opt bits E(32554) CCDS12675.1 RSPH6A gene_id:81492|Hs108|chr19 ( 717) 4891 781.3 0 CCDS34521.1 RSPH4A gene_id:345895|Hs108|chr6 ( 716) 1978 322.8 1.1e-87 CCDS55051.1 RSPH4A gene_id:345895|Hs108|chr6 ( 600) 1245 207.4 5e-53 >>CCDS12675.1 RSPH6A gene_id:81492|Hs108|chr19 (717 aa) initn: 4891 init1: 4891 opt: 4891 Z-score: 4165.3 bits: 781.3 E(32554): 0 Smith-Waterman score: 4891; 100.0% identity (100.0% similar) in 717 aa overlap (1-717:1-717) 10 20 30 40 50 60 pF1KB8 MGDLPPYPERPAQQPPGRRTSQASQRRHSRDQAQALAADPEERQQIPPDAQRNAPGWSQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MGDLPPYPERPAQQPPGRRTSQASQRRHSRDQAQALAADPEERQQIPPDAQRNAPGWSQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GSLSQQENLLMPQVFQAEEARLGGMEYPSVNTGFPSEFQPQPYSDESRMQVAELTTSLML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 GSLSQQENLLMPQVFQAEEARLGGMEYPSVNTGFPSEFQPQPYSDESRMQVAELTTSLML 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QRLQQGQSSLFQQLDPTFQEPPVNPLGQFNLYQTDQFSEGAQHGPYIRDDPALQFLPSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 QRLQQGQSSLFQQLDPTFQEPPVNPLGQFNLYQTDQFSEGAQHGPYIRDDPALQFLPSEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GFPHYSAQVPEPEPLELAVQNAKAYLLQTSINCDLSLYEHLVNLLTKILNQRPEDPLSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 GFPHYSAQVPEPEPLELAVQNAKAYLLQTSINCDLSLYEHLVNLLTKILNQRPEDPLSVL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ESLNRTTQWEWFHPKLDTLRDDPEMQPTYKMAEKQKALFTRSGGGTEGEQEMEEEVGETP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 ESLNRTTQWEWFHPKLDTLRDDPEMQPTYKMAEKQKALFTRSGGGTEGEQEMEEEVGETP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VPNIMETAFYFEQAGVGLSSDESFRIFLAMKQLVEQQPIHTCRFWGKILGIKRSYLVAEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 VPNIMETAFYFEQAGVGLSSDESFRIFLAMKQLVEQQPIHTCRFWGKILGIKRSYLVAEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 EFREGEEEAEEEEVEEMTEGGEVMEAHGEEEGEEDEEKAVDIVPKSVWKPPPVIPKEESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 EFREGEEEAEEEEVEEMTEGGEVMEAHGEEEGEEDEEKAVDIVPKSVWKPPPVIPKEESR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SGANKYLYFVCNEPGLPWTRLPHVTPAQIVNARKIKKFFTGYLDTPVVSYPPFPGNEANY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 SGANKYLYFVCNEPGLPWTRLPHVTPAQIVNARKIKKFFTGYLDTPVVSYPPFPGNEANY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 LRAQIARISAATQVSPLGFYQFSEEEGDEEEEGGAGRDSYEENPDFEGIPVLELVDSMAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LRAQIARISAATQVSPLGFYQFSEEEGDEEEEGGAGRDSYEENPDFEGIPVLELVDSMAN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 WVHHTQHILPQGRCTWVNPLQKTEEEEDLGEEEEKADEGPEEVEQEVGPPLLTPLSEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 WVHHTQHILPQGRCTWVNPLQKTEEEEDLGEEEEKADEGPEEVEQEVGPPLLTPLSEDAE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 IMHLAPWTTRLSCSLCPQYSVAVVRSNLWPGAYAYASGKKFENIYIGWGHKYSPESFNPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 IMHLAPWTTRLSCSLCPQYSVAVVRSNLWPGAYAYASGKKFENIYIGWGHKYSPESFNPA 610 620 630 640 650 660 670 680 690 700 710 pF1KB8 LPAPIQQEYPSGPEIMEMSDPTVEEEQALKAAQEQALGATEEEEEGEEEEEGEETDD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LPAPIQQEYPSGPEIMEMSDPTVEEEQALKAAQEQALGATEEEEEGEEEEEGEETDD 670 680 690 700 710 >>CCDS34521.1 RSPH4A gene_id:345895|Hs108|chr6 (716 aa) initn: 1905 init1: 914 opt: 1978 Z-score: 1687.7 bits: 322.8 E(32554): 1.1e-87 Smith-Waterman score: 2305; 51.5% identity (76.5% similar) in 714 aa overlap (8-716:42-716) 10 20 30 pF1KB8 MGDLPPYPERPAQQPPGRRTSQASQRRHSRDQAQALA : . : : : :..:. ...:.. CCDS34 ENQEELGETRRPWEGKTAASPQYSEPESSEPLEAKQGPETGRQSRSSRPWSPQSRAKTPL 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB8 ADPE--ERQQIPPDAQRNAPGWSQRGSLSQQENLLMPQVFQAEEARLGGMEYPSVNTGFP . : : .. : . :. :. : ...: : :.. : .. : ..: .: CCDS34 GGPAGPETSSPAPVSPRE-PSSSPSPLAPARQDLAAPP--QSD--RTTSV-IPEAGTPYP 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 SEFQPQPYSDESRMQVAELTTSLMLQRLQQGQSSLFQQLDPTFQEPPVNPLGQFNLYQTD . .. . . :: . . . . .:. :: . : . : .... . : .:...: . CCDS34 DPLEQSSDKRESTPHHTSQSEGNTFQQSQQPKPHLCGRRDVSYNNAKQKEL-RFDVFQEE 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB8 QFSEGAQHGPYIRDDPALQFLPSELGFPHYSAQVPEPEPLELAVQNAKAYLLQTSINCDL . ... : ..:: :. ...: : ::...::::::::.:: : . CCDS34 D-----SNSDYDLQQPA----PG-------GSEVA-PSMLEITIQNAKAYLLKTSSNSGF 190 200 210 220 220 230 240 250 260 270 pF1KB8 SLYEHLVNLLTKILNQRPEDPLSVLESLNRTTQWEWFHPKLDTLRDDPEMQPTYKMAEKQ .::.:: :.::::::.:::. ....:.... .. : :.:.:... :. :::..:::: CCDS34 NLYDHLSNMLTKILNERPENAVDIFENISQDVKMAHFSKKFDALQNENELLPTYEIAEKQ 230 240 250 260 270 280 280 290 300 310 320 330 pF1KB8 KALFTRSGGGTEG-EQEMEEEVGETPVPNIMETAFYFEQAGVGLSSDESFRIFLAMKQLV :::: . : :: .::.:.:..:. .::.::.:::::::::::..::..:::::.:::. CCDS34 KALFLQ--GHLEGVDQELEDEIAENALPNVMESAFYFEQAGVGLGTDETYRIFLALKQLT 290 300 310 320 330 340 340 350 360 370 380 390 pF1KB8 EQQPIHTCRFWGKILGIKRSYLVAEVEFREGE--EEAEEEEVEEMTEGGEVMEAHGEEEG . .::. :::::::::.. .:.:::::::::: ::.:::.: : ..:: ::: : CCDS34 DTHPIQRCRFWGKILGLEMNYIVAEVEFREGEDEEEVEEEDVAEERDNGES-EAH---ED 350 360 370 380 390 400 400 410 420 430 440 450 pF1KB8 EEDEEKAVDIVPKSVWKPPPVIPKEESRSGANKYLYFVCNEPGLPWTRLPHVTPAQIVNA :::: .::: .: : .:::::::.:::::.:::::::: ::..:: : ::::: : CCDS34 EEDE------LPKSFYKAPQAIPKEESRTGANKYVYFVCNEPGRPWVKLPPVIPAQIVIA 410 420 430 440 450 460 470 480 490 500 510 pF1KB8 RKIKKFFTGYLDTPVVSYPPFPGNEANYLRAQIARISAATQVSPLGFYQFSEEEGDEEEE ::::::::: ::.:..:::::::::.::::::::::::.:.:::::::::.::::.:::: CCDS34 RKIKKFFTGRLDAPIISYPPFPGNESNYLRAQIARISAGTHVSPLGFYQFGEEEGEEEEE 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB8 GGAGRDSYEENPDFEGIPVLELVDSMANWVHHTQHILPQGRCTWVNPLQKTEEEEDLGEE . .::.:.::::::::: :..::.:..:::::.:::: ::::.: : .::.::::. :: CCDS34 AEGGRNSFEENPDFEGIQVIDLVESLSNWVHHVQHILSQGRCNWFNSIQKNEEEEE--EE 520 530 540 550 560 570 580 590 600 610 620 630 pF1KB8 EEKADEGPEEVEQEVGPPLLTPLSEDAEIMHLAPWTTRLSCSLCPQYSVAVVRSNLWPGA .:. :.. . .::::: :::::.::: ::... ::::::: .: :::..::..::::::: CCDS34 DEEKDDS-DYIEQEVGLPLLTPISEDLEIQNIPPWTTRLSSNLIPQYAIAVLQSNLWPGA 580 590 600 610 620 630 640 650 660 670 680 690 pF1KB8 YAYASGKKFENIYIGWGHKYSPESFNPALPAPIQQEYPSGPEIMEMSDPTVEEEQALKAA ::...::::::.::::::::::....: .: :. ::::::::: ::.::.::::::..:: CCDS34 YAFSNGKKFENFYIGWGHKYSPDNYTPPVPPPVYQEYPSGPEITEMDDPSVEEEQAFRAA 640 650 660 670 680 690 700 710 pF1KB8 QEQALGATEEEEEGEEEEEGEETDD :: .: :.:.:: :.:.: .. : CCDS34 QEAVLLAAENEESEEDEDEEDDYD 700 710 >>CCDS55051.1 RSPH4A gene_id:345895|Hs108|chr6 (600 aa) initn: 1504 init1: 810 opt: 1245 Z-score: 1065.4 bits: 207.4 E(32554): 5e-53 Smith-Waterman score: 1572; 48.5% identity (73.2% similar) in 549 aa overlap (8-551:42-554) 10 20 30 pF1KB8 MGDLPPYPERPAQQPPGRRTSQASQRRHSRDQAQALA : . : : : :..:. ...:.. CCDS55 ENQEELGETRRPWEGKTAASPQYSEPESSEPLEAKQGPETGRQSRSSRPWSPQSRAKTPL 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB8 ADPE--ERQQIPPDAQRNAPGWSQRGSLSQQENLLMPQVFQAEEARLGGMEYPSVNTGFP . : : .. : . :. :. : ...: : :.. : .. : ..: .: CCDS55 GGPAGPETSSPAPVSPRE-PSSSPSPLAPARQDLAAPP--QSD--RTTSV-IPEAGTPYP 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 SEFQPQPYSDESRMQVAELTTSLMLQRLQQGQSSLFQQLDPTFQEPPVNPLGQFNLYQTD . .. . . :: . . . . .:. :: . : . : .... . : .:...: CCDS55 DPLEQSSDKRESTPHHTSQSEGNTFQQSQQPKPHLCGRRDVSYNNAKQKEL-RFDVFQ-- 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB8 QFSEGAQHGPYIRDDPALQFLPSELGFPHYSAQVPEPEPLELAVQNAKAYLLQTSINCDL : ... : ..:: :. ...: : ::...::::::::.:: : . CCDS55 ---EEDSNSDYDLQQPA----PG-------GSEVA-PSMLEITIQNAKAYLLKTSSNSGF 190 200 210 220 220 230 240 250 260 270 pF1KB8 SLYEHLVNLLTKILNQRPEDPLSVLESLNRTTQWEWFHPKLDTLRDDPEMQPTYKMAEKQ .::.:: :.::::::.:::. ....:.... .. : :.:.:... :. :::..:::: CCDS55 NLYDHLSNMLTKILNERPENAVDIFENISQDVKMAHFSKKFDALQNENELLPTYEIAEKQ 230 240 250 260 270 280 280 290 300 310 320 330 pF1KB8 KALFTRSGGGTEG-EQEMEEEVGETPVPNIMETAFYFEQAGVGLSSDESFRIFLAMKQLV :::: . : :: .::.:.:..:. .::.::.:::::::::::..::..:::::.:::. CCDS55 KALFLQ--GHLEGVDQELEDEIAENALPNVMESAFYFEQAGVGLGTDETYRIFLALKQLT 290 300 310 320 330 340 340 350 360 370 380 390 pF1KB8 EQQPIHTCRFWGKILGIKRSYLVAEVEFREGE--EEAEEEEVEEMTEGGEVMEAHGEEEG . .::. :::::::::.. .:.:::::::::: ::.:::.: : ..:: ::: : CCDS55 DTHPIQRCRFWGKILGLEMNYIVAEVEFREGEDEEEVEEEDVAEERDNGES-EAH---ED 350 360 370 380 390 400 400 410 420 430 440 450 pF1KB8 EEDEEKAVDIVPKSVWKPPPVIPKEESRSGANKYLYFVCNEPGLPWTRLPHVTPAQIVNA :::: .::: .: : .:::::::.:::::.:::::::: ::..:: : ::::: : CCDS55 EEDE------LPKSFYKAPQAIPKEESRTGANKYVYFVCNEPGRPWVKLPPVIPAQIVIA 410 420 430 440 450 460 470 480 490 500 510 pF1KB8 RKIKKFFTGYLDTPVVSYPPFPGNEANYLRAQIARISAATQVSPLGFYQFSEEEGDEEEE ::::::::: ::.:..:::::::::.::::::::::::.:.:::::::::.::::.:::: CCDS55 RKIKKFFTGRLDAPIISYPPFPGNESNYLRAQIARISAGTHVSPLGFYQFGEEEGEEEEE 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB8 GGAGRDSYEENPDFEGIPVLELVDSMANWVHHTQHILPQGRCTWVNPLQKTEEEEDLGEE . .::.:.::::::::: :..::.:..:::::.:::: : CCDS55 AEGGRNSFEENPDFEGIQVIDLVESLSNWVHHVQHILSQRFRIYPPGQHGYPQISFHNML 520 530 540 550 560 570 580 590 600 610 620 630 pF1KB8 EEKADEGPEEVEQEVGPPLLTPLSEDAEIMHLAPWTTRLSCSLCPQYSVAVVRSNLWPGA CCDS55 LQSFNPTFGLEHMPSPMAKSLKIST 580 590 600 717 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 22:10:01 2016 done: Sat Nov 5 22:10:01 2016 Total Scan time: 3.290 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]