FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8693, 538 aa 1>>>pF1KB8693 538 - 538 aa - 538 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7076+/-0.000807; mu= 16.1304+/- 0.049 mean_var=66.7629+/-13.430, 0's: 0 Z-trim(107.4): 24 B-trim: 0 in 0/51 Lambda= 0.156966 statistics sampled from 9536 (9553) to 9536 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.293), width: 16 Scan time: 3.530 The best scores are: opt bits E(32554) CCDS43045.1 MTMR14 gene_id:64419|Hs108|chr3 ( 538) 3595 823.1 0 CCDS43044.1 MTMR14 gene_id:64419|Hs108|chr3 ( 598) 3234 741.3 7.2e-214 CCDS43043.1 MTMR14 gene_id:64419|Hs108|chr3 ( 650) 3234 741.3 7.7e-214 >>CCDS43045.1 MTMR14 gene_id:64419|Hs108|chr3 (538 aa) initn: 3595 init1: 3595 opt: 3595 Z-score: 4395.7 bits: 823.1 E(32554): 0 Smith-Waterman score: 3595; 99.8% identity (99.8% similar) in 538 aa overlap (1-538:1-538) 10 20 30 40 50 60 pF1KB8 MAGARAAAAAASAGSSASSGNQPPQELGLGELLEEFSRTQYRAKDGSGTGGSKVGRIEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: CCDS43 MAGARAAAAAASAGSSASSGNQPPQELGLGELLEEFSRTQYRAKDGSGTGGSKVERIEKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 CLELFGRDYCFSVIPNTNGDICGHYPRHIVFLEYESSEKEKDTFESTVQVSKLQDLIHRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 CLELFGRDYCFSVIPNTNGDICGHYPRHIVFLEYESSEKEKDTFESTVQVSKLQDLIHRS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 KMARCRGRFVCPVILFKGKHICRSATLAGWGELYGRSGYNYFFSGGADDAWADVEDVTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KMARCRGRFVCPVILFKGKHICRSATLAGWGELYGRSGYNYFFSGGADDAWADVEDVTEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 DCALRSGDTHLFDKVRGYDIKLLRYLSVKYICDLMVENKKVKFGMNVTSSEKVDKAQRYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DCALRSGDTHLFDKVRGYDIKLLRYLSVKYICDLMVENKKVKFGMNVTSSEKVDKAQRYA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 DFTLLSIPYPGCEFFKEYKDRDYMAEGLIFNWKQDYVDAPLSIPDFLTHSLNIDWSQYQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DFTLLSIPYPGCEFFKEYKDRDYMAEGLIFNWKQDYVDAPLSIPDFLTHSLNIDWSQYQC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 WDLVQQTQNYLKLLLSLVNSDDDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 WDLVQQTQNYLKLLLSLVNSDDDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 TEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 GGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAWLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAWLA 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 ALSDRETRLQEVRSAFLAAYSSTVGLRAVAPSPSGAIGGLLEQFARGVGLRSISSNAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 ALSDRETRLQEVRSAFLAAYSSTVGLRAVAPSPSGAIGGLLEQFARGVGLRSISSNAL 490 500 510 520 530 >>CCDS43044.1 MTMR14 gene_id:64419|Hs108|chr3 (598 aa) initn: 3581 init1: 3234 opt: 3234 Z-score: 3953.1 bits: 741.3 E(32554): 7.2e-214 Smith-Waterman score: 3288; 89.3% identity (89.3% similar) in 570 aa overlap (1-510:1-570) 10 20 30 40 50 60 pF1KB8 MAGARAAAAAASAGSSASSGNQPPQELGLGELLEEFSRTQYRAKDGSGTGGSKVGRIEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: CCDS43 MAGARAAAAAASAGSSASSGNQPPQELGLGELLEEFSRTQYRAKDGSGTGGSKVERIEKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 CLELFGRDYCFSVIPNTNGDICGHYPRHIVFLEYESSEKEKDTFESTVQVSKLQDLIHRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 CLELFGRDYCFSVIPNTNGDICGHYPRHIVFLEYESSEKEKDTFESTVQVSKLQDLIHRS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 KMARCRGRFVCPVILFKGKHICRSATLAGWGELYGRSGYNYFFSGGADDAWADVEDVTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KMARCRGRFVCPVILFKGKHICRSATLAGWGELYGRSGYNYFFSGGADDAWADVEDVTEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 DCALRSGDTHLFDKVRGYDIKLLRYLSVKYICDLMVENKKVKFGMNVTSSEKVDKAQRYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DCALRSGDTHLFDKVRGYDIKLLRYLSVKYICDLMVENKKVKFGMNVTSSEKVDKAQRYA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 DFTLLSIPYPGCEFFKEYKDRDYMAEGLIFNWKQDYVDAPLSIPDFLTHSLNIDWSQYQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DFTLLSIPYPGCEFFKEYKDRDYMAEGLIFNWKQDYVDAPLSIPDFLTHSLNIDWSQYQC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 WDLVQQTQNYLKLLLSLVNSDDDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 WDLVQQTQNYLKLLLSLVNSDDDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 TEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARD 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 GGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAW-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAWRK 430 440 450 460 470 480 480 pF1KB8 ----------------------------------------------------------LA :: CCDS43 SHSSSPQSVLWNRPQPSEDRLPSQQGLAEARSSSSSSSNHSDNFFRMGSSPLEVPKPRLA 490 500 510 520 530 540 490 500 510 520 530 pF1KB8 ALSDRETRLQEVRSAFLAAYSSTVGLRAVAPSPSGAIGGLLEQFARGVGLRSISSNAL :::::::::::::::::::::::::::::: CCDS43 ALSDRETRLQEVRSAFLAAYSSTVGLRAVAPSPSGAIGGLLEQFARGVGLRSISSNAL 550 560 570 580 590 >>CCDS43043.1 MTMR14 gene_id:64419|Hs108|chr3 (650 aa) initn: 3581 init1: 3234 opt: 3234 Z-score: 3952.5 bits: 741.3 E(32554): 7.7e-214 Smith-Waterman score: 3234; 99.8% identity (99.8% similar) in 478 aa overlap (1-478:1-478) 10 20 30 40 50 60 pF1KB8 MAGARAAAAAASAGSSASSGNQPPQELGLGELLEEFSRTQYRAKDGSGTGGSKVGRIEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: CCDS43 MAGARAAAAAASAGSSASSGNQPPQELGLGELLEEFSRTQYRAKDGSGTGGSKVERIEKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 CLELFGRDYCFSVIPNTNGDICGHYPRHIVFLEYESSEKEKDTFESTVQVSKLQDLIHRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 CLELFGRDYCFSVIPNTNGDICGHYPRHIVFLEYESSEKEKDTFESTVQVSKLQDLIHRS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 KMARCRGRFVCPVILFKGKHICRSATLAGWGELYGRSGYNYFFSGGADDAWADVEDVTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KMARCRGRFVCPVILFKGKHICRSATLAGWGELYGRSGYNYFFSGGADDAWADVEDVTEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 DCALRSGDTHLFDKVRGYDIKLLRYLSVKYICDLMVENKKVKFGMNVTSSEKVDKAQRYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DCALRSGDTHLFDKVRGYDIKLLRYLSVKYICDLMVENKKVKFGMNVTSSEKVDKAQRYA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 DFTLLSIPYPGCEFFKEYKDRDYMAEGLIFNWKQDYVDAPLSIPDFLTHSLNIDWSQYQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DFTLLSIPYPGCEFFKEYKDRDYMAEGLIFNWKQDYVDAPLSIPDFLTHSLNIDWSQYQC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 WDLVQQTQNYLKLLLSLVNSDDDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 WDLVQQTQNYLKLLLSLVNSDDDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 TEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 GGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAWLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAWRK 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 ALSDRETRLQEVRSAFLAAYSSTVGLRAVAPSPSGAIGGLLEQFARGVGLRSISSNAL CCDS43 SHSSSPQSVLWNRPQPSEDRLPSQQGLAEARSSSSSSSNHSDNFFRMGSSPLEVPKPRSV 490 500 510 520 530 540 >-- initn: 396 init1: 361 opt: 361 Z-score: 436.4 bits: 90.7 E(32554): 5.5e-18 Smith-Waterman score: 361; 100.0% identity (100.0% similar) in 60 aa overlap (479-538:591-650) 450 460 470 480 490 500 pF1KB8 VMESSPGATGSFTYEAVELVPAGAPTQAAWLAALSDRETRLQEVRSAFLAAYSSTVGLRA :::::::::::::::::::::::::::::: CCDS43 GCGSIQERAVLHTDSSLPFSFPDELPNSCLLAALSDRETRLQEVRSAFLAAYSSTVGLRA 570 580 590 600 610 620 510 520 530 pF1KB8 VAPSPSGAIGGLLEQFARGVGLRSISSNAL :::::::::::::::::::::::::::::: CCDS43 VAPSPSGAIGGLLEQFARGVGLRSISSNAL 630 640 650 538 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:39:58 2016 done: Fri Nov 4 14:39:58 2016 Total Scan time: 3.530 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]