FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8697, 546 aa 1>>>pF1KB8697 546 - 546 aa - 546 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.4701+/-0.000444; mu= -12.9237+/- 0.028 mean_var=523.3755+/-107.674, 0's: 0 Z-trim(123.1): 64 B-trim: 0 in 0/60 Lambda= 0.056062 statistics sampled from 42336 (42409) to 42336 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.497), width: 16 Scan time: 11.280 The best scores are: opt bits E(85289) XP_016856051 (OMIM: 608676) PREDICTED: alpha-taxil ( 546) 3544 301.4 4.9e-81 NP_787048 (OMIM: 608676) alpha-taxilin [Homo sapie ( 546) 3544 301.4 4.9e-81 XP_016856052 (OMIM: 608676) PREDICTED: alpha-taxil ( 579) 2449 212.8 2.3e-54 XP_016856050 (OMIM: 608676) PREDICTED: alpha-taxil ( 579) 2449 212.8 2.3e-54 XP_016856053 (OMIM: 608676) PREDICTED: alpha-taxil ( 371) 2374 206.6 1.1e-52 XP_016856054 (OMIM: 608676) PREDICTED: alpha-taxil ( 371) 2374 206.6 1.1e-52 XP_011539234 (OMIM: 608676) PREDICTED: alpha-taxil ( 386) 2228 194.8 4.2e-49 XP_011539233 (OMIM: 608676) PREDICTED: alpha-taxil ( 386) 2228 194.8 4.2e-49 NP_060830 (OMIM: 300677) gamma-taxilin isoform 1 [ ( 528) 1612 145.1 5.2e-34 XP_011533807 (OMIM: 611438) PREDICTED: beta-taxili ( 684) 1501 136.2 3.2e-31 XP_016865811 (OMIM: 611438) PREDICTED: beta-taxili ( 684) 1501 136.2 3.2e-31 NP_694967 (OMIM: 611438) beta-taxilin [Homo sapien ( 684) 1501 136.2 3.2e-31 XP_005266893 (OMIM: 611438) PREDICTED: beta-taxili ( 684) 1501 136.2 3.2e-31 NP_001162154 (OMIM: 300677) gamma-taxilin isoform ( 396) 1413 128.9 3e-29 XP_011533808 (OMIM: 611438) PREDICTED: beta-taxili ( 536) 1393 127.4 1.1e-28 XP_016885120 (OMIM: 300677) PREDICTED: gamma-taxil ( 323) 1128 105.7 2.3e-22 >>XP_016856051 (OMIM: 608676) PREDICTED: alpha-taxilin i (546 aa) initn: 3544 init1: 3544 opt: 3544 Z-score: 1575.9 bits: 301.4 E(85289): 4.9e-81 Smith-Waterman score: 3544; 99.6% identity (100.0% similar) in 546 aa overlap (1-546:1-546) 10 20 30 40 50 60 pF1KB8 MKNQDKKNGAAQQSNPKSSPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPRKPEGAQA :::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKNQDKKNGAAKQSNPKSSPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPRKPEGAQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RTAQSGALRDVSEELSRQLEDILSTYCVDNNQGGPGEDGAQGEPAEPEDAEKSRTYVARN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTAQSGALRDVSEELSRQLEDILSTYCVDNNQGGPGEDGAQGEPAEPEDAEKSRTYVARN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GEPEPTPVVNGEKEPSKGDPNTEEIRQSDEVGDRDHRRPQEKKKAKGLGKEITLLMQTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEPEPTPVVNGEKEPSKGDPNTEEIRQSDEVGDRDHRRPQEKKKAKGLGKEITLLMQTLN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TLSTPEEKLAALCKKYAELLEEHRNSQKQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLSTPEEKLAALCKKYAELLEEHRNSQKQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LESLCRELQRHNRSLKEEGVQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LESLCRELQRHNRSLKEEGVQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ENMELAERLKKLIEQYELREEHIDKVFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENMELAERLKKLIEQYELREEHIDKVFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 FLLKEAVESQRMCELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFEQEMEKMTK :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: XP_016 FLLKEAVESQRMCELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFKQEMEKMTK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 KIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVKIQRLEKLCRALQTERND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVKIQRLEKLCRALQTERND 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 LNKRVQDLSAGGQGSLTDSGPERRPEGPGAQAPSSPRVTEAPCYPGAPSTEASGQTGPQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNKRVQDLSAGGQGSLTDSGPERRPEGPGAQAPSSPRVTEAPCYPGAPSTEASGQTGPQE 490 500 510 520 530 540 pF1KB8 PTSARA :::::: XP_016 PTSARA >>NP_787048 (OMIM: 608676) alpha-taxilin [Homo sapiens] (546 aa) initn: 3544 init1: 3544 opt: 3544 Z-score: 1575.9 bits: 301.4 E(85289): 4.9e-81 Smith-Waterman score: 3544; 99.6% identity (100.0% similar) in 546 aa overlap (1-546:1-546) 10 20 30 40 50 60 pF1KB8 MKNQDKKNGAAQQSNPKSSPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPRKPEGAQA :::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::: NP_787 MKNQDKKNGAAKQSNPKSSPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPRKPEGAQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RTAQSGALRDVSEELSRQLEDILSTYCVDNNQGGPGEDGAQGEPAEPEDAEKSRTYVARN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 RTAQSGALRDVSEELSRQLEDILSTYCVDNNQGGPGEDGAQGEPAEPEDAEKSRTYVARN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GEPEPTPVVNGEKEPSKGDPNTEEIRQSDEVGDRDHRRPQEKKKAKGLGKEITLLMQTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 GEPEPTPVVNGEKEPSKGDPNTEEIRQSDEVGDRDHRRPQEKKKAKGLGKEITLLMQTLN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TLSTPEEKLAALCKKYAELLEEHRNSQKQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 TLSTPEEKLAALCKKYAELLEEHRNSQKQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LESLCRELQRHNRSLKEEGVQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 LESLCRELQRHNRSLKEEGVQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ENMELAERLKKLIEQYELREEHIDKVFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 ENMELAERLKKLIEQYELREEHIDKVFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 FLLKEAVESQRMCELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFEQEMEKMTK :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: NP_787 FLLKEAVESQRMCELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFKQEMEKMTK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 KIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVKIQRLEKLCRALQTERND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 KIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVKIQRLEKLCRALQTERND 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 LNKRVQDLSAGGQGSLTDSGPERRPEGPGAQAPSSPRVTEAPCYPGAPSTEASGQTGPQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 LNKRVQDLSAGGQGSLTDSGPERRPEGPGAQAPSSPRVTEAPCYPGAPSTEASGQTGPQE 490 500 510 520 530 540 pF1KB8 PTSARA :::::: NP_787 PTSARA >>XP_016856052 (OMIM: 608676) PREDICTED: alpha-taxilin i (579 aa) initn: 2414 init1: 2414 opt: 2449 Z-score: 1096.9 bits: 212.8 E(85289): 2.3e-54 Smith-Waterman score: 3461; 93.9% identity (94.3% similar) in 578 aa overlap (2-546:2-579) 10 20 30 40 50 60 pF1KB8 MKNQDKKNGAAQQSNPKSSPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPRKPEGAQA ::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKNQDKKNGAAKQSNPKSSPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPRKPEGAQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RTAQSGALRDVSEELSRQLEDILSTYCVDNNQGGPGEDGAQGEPAEPEDAEKSRTYVARN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTAQSGALRDVSEELSRQLEDILSTYCVDNNQGGPGEDGAQGEPAEPEDAEKSRTYVARN 70 80 90 100 110 120 130 140 150 160 pF1KB8 GEPEPTPVVNGEKEPSKGDPNTEEIRQSDEVGDRDHRRPQEKKKAKGLG----------- ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEPEPTPVVNGEKEPSKGDPNTEEIRQSDEVGDRDHRRPQEKKKAKGLGEQRAALCEAGE 130 140 150 160 170 180 170 180 190 200 pF1KB8 ----------------------KEITLLMQTLNTLSTPEEKLAALCKKYAELLEEHRNSQ :::::::::::::::::::::::::::::::::::::: XP_016 EREFGLDVLWASLFCQDSKENGKEITLLMQTLNTLSTPEEKLAALCKKYAELLEEHRNSQ 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB8 KQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRAREEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRAREEE 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB8 EKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDKVF 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB8 KHKDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLLKEAVESQRMCELMKQQETHLKQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KHKDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLLKEAVESQRMCELMKQQETHLKQQL 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB8 ALYTEKFEEFQNTLSKSSEVFTTFEQEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMA ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_016 ALYTEKFEEFQNTLSKSSEVFTTFKQEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMA 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB8 EEKTVRDKELEGLQVKIQRLEKLCRALQTERNDLNKRVQDLSAGGQGSLTDSGPERRPEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEKTVRDKELEGLQVKIQRLEKLCRALQTERNDLNKRVQDLSAGGQGSLTDSGPERRPEG 490 500 510 520 530 540 510 520 530 540 pF1KB8 PGAQAPSSPRVTEAPCYPGAPSTEASGQTGPQEPTSARA ::::::::::::::::::::::::::::::::::::::: XP_016 PGAQAPSSPRVTEAPCYPGAPSTEASGQTGPQEPTSARA 550 560 570 >>XP_016856050 (OMIM: 608676) PREDICTED: alpha-taxilin i (579 aa) initn: 2414 init1: 2414 opt: 2449 Z-score: 1096.9 bits: 212.8 E(85289): 2.3e-54 Smith-Waterman score: 3461; 93.9% identity (94.3% similar) in 578 aa overlap (2-546:2-579) 10 20 30 40 50 60 pF1KB8 MKNQDKKNGAAQQSNPKSSPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPRKPEGAQA ::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKNQDKKNGAAKQSNPKSSPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPRKPEGAQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RTAQSGALRDVSEELSRQLEDILSTYCVDNNQGGPGEDGAQGEPAEPEDAEKSRTYVARN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTAQSGALRDVSEELSRQLEDILSTYCVDNNQGGPGEDGAQGEPAEPEDAEKSRTYVARN 70 80 90 100 110 120 130 140 150 160 pF1KB8 GEPEPTPVVNGEKEPSKGDPNTEEIRQSDEVGDRDHRRPQEKKKAKGLG----------- ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEPEPTPVVNGEKEPSKGDPNTEEIRQSDEVGDRDHRRPQEKKKAKGLGEQRAALCEAGE 130 140 150 160 170 180 170 180 190 200 pF1KB8 ----------------------KEITLLMQTLNTLSTPEEKLAALCKKYAELLEEHRNSQ :::::::::::::::::::::::::::::::::::::: XP_016 EREFGLDVLWASLFCQDSKENGKEITLLMQTLNTLSTPEEKLAALCKKYAELLEEHRNSQ 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB8 KQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRAREEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRAREEE 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB8 EKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDKVF 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB8 KHKDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLLKEAVESQRMCELMKQQETHLKQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KHKDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLLKEAVESQRMCELMKQQETHLKQQL 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB8 ALYTEKFEEFQNTLSKSSEVFTTFEQEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMA ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_016 ALYTEKFEEFQNTLSKSSEVFTTFKQEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMA 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB8 EEKTVRDKELEGLQVKIQRLEKLCRALQTERNDLNKRVQDLSAGGQGSLTDSGPERRPEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEKTVRDKELEGLQVKIQRLEKLCRALQTERNDLNKRVQDLSAGGQGSLTDSGPERRPEG 490 500 510 520 530 540 510 520 530 540 pF1KB8 PGAQAPSSPRVTEAPCYPGAPSTEASGQTGPQEPTSARA ::::::::::::::::::::::::::::::::::::::: XP_016 PGAQAPSSPRVTEAPCYPGAPSTEASGQTGPQEPTSARA 550 560 570 >>XP_016856053 (OMIM: 608676) PREDICTED: alpha-taxilin i (371 aa) initn: 2374 init1: 2374 opt: 2374 Z-score: 1066.6 bits: 206.6 E(85289): 1.1e-52 Smith-Waterman score: 2374; 99.7% identity (100.0% similar) in 371 aa overlap (176-546:1-371) 150 160 170 180 190 200 pF1KB8 RQSDEVGDRDHRRPQEKKKAKGLGKEITLLMQTLNTLSTPEEKLAALCKKYAELLEEHRN :::::::::::::::::::::::::::::: XP_016 MQTLNTLSTPEEKLAALCKKYAELLEEHRN 10 20 30 210 220 230 240 250 260 pF1KB8 SQKQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQKQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRARE 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB8 EEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDK 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB8 VFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLLKEAVESQRMCELMKQQETHLKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLLKEAVESQRMCELMKQQETHLKQ 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB8 QLALYTEKFEEFQNTLSKSSEVFTTFEQEMEKMTKKIKKLEKETTMYRSRWESSNKALLE ::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::: XP_016 QLALYTEKFEEFQNTLSKSSEVFTTFKQEMEKMTKKIKKLEKETTMYRSRWESSNKALLE 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB8 MAEEKTVRDKELEGLQVKIQRLEKLCRALQTERNDLNKRVQDLSAGGQGSLTDSGPERRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAEEKTVRDKELEGLQVKIQRLEKLCRALQTERNDLNKRVQDLSAGGQGSLTDSGPERRP 280 290 300 310 320 330 510 520 530 540 pF1KB8 EGPGAQAPSSPRVTEAPCYPGAPSTEASGQTGPQEPTSARA ::::::::::::::::::::::::::::::::::::::::: XP_016 EGPGAQAPSSPRVTEAPCYPGAPSTEASGQTGPQEPTSARA 340 350 360 370 >>XP_016856054 (OMIM: 608676) PREDICTED: alpha-taxilin i (371 aa) initn: 2374 init1: 2374 opt: 2374 Z-score: 1066.6 bits: 206.6 E(85289): 1.1e-52 Smith-Waterman score: 2374; 99.7% identity (100.0% similar) in 371 aa overlap (176-546:1-371) 150 160 170 180 190 200 pF1KB8 RQSDEVGDRDHRRPQEKKKAKGLGKEITLLMQTLNTLSTPEEKLAALCKKYAELLEEHRN :::::::::::::::::::::::::::::: XP_016 MQTLNTLSTPEEKLAALCKKYAELLEEHRN 10 20 30 210 220 230 240 250 260 pF1KB8 SQKQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQKQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRARE 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB8 EEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDK 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB8 VFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLLKEAVESQRMCELMKQQETHLKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLLKEAVESQRMCELMKQQETHLKQ 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB8 QLALYTEKFEEFQNTLSKSSEVFTTFEQEMEKMTKKIKKLEKETTMYRSRWESSNKALLE ::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::: XP_016 QLALYTEKFEEFQNTLSKSSEVFTTFKQEMEKMTKKIKKLEKETTMYRSRWESSNKALLE 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB8 MAEEKTVRDKELEGLQVKIQRLEKLCRALQTERNDLNKRVQDLSAGGQGSLTDSGPERRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAEEKTVRDKELEGLQVKIQRLEKLCRALQTERNDLNKRVQDLSAGGQGSLTDSGPERRP 280 290 300 310 320 330 510 520 530 540 pF1KB8 EGPGAQAPSSPRVTEAPCYPGAPSTEASGQTGPQEPTSARA ::::::::::::::::::::::::::::::::::::::::: XP_016 EGPGAQAPSSPRVTEAPCYPGAPSTEASGQTGPQEPTSARA 340 350 360 370 >>XP_011539234 (OMIM: 608676) PREDICTED: alpha-taxilin i (386 aa) initn: 2228 init1: 2228 opt: 2228 Z-score: 1002.5 bits: 194.8 E(85289): 4.2e-49 Smith-Waterman score: 2228; 98.6% identity (98.9% similar) in 353 aa overlap (194-546:34-386) 170 180 190 200 210 220 pF1KB8 KAKGLGKEITLLMQTLNTLSTPEEKLAALCKKYAELLEEHRNSQKQMKLLQKKQSQLVQE :: :::::::::::::::::::::::: XP_011 RNPPRGIQTQKRSGRVTRSETETIEGHRRRKKPRVWLEEHRNSQKQMKLLQKKQSQLVQE 10 20 30 40 50 60 230 240 250 260 270 280 pF1KB8 KDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRAREEEEKRKEVTSHFQVTLND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRAREEEEKRKEVTSHFQVTLND 70 80 90 100 110 120 290 300 310 320 330 340 pF1KB8 IQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDKVFKHKDLQQQLVDAKLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDKVFKHKDLQQQLVDAKLQQ 130 140 150 160 170 180 350 360 370 380 390 400 pF1KB8 AQEMLKEAEERHQREKDFLLKEAVESQRMCELMKQQETHLKQQLALYTEKFEEFQNTLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQEMLKEAEERHQREKDFLLKEAVESQRMCELMKQQETHLKQQLALYTEKFEEFQNTLSK 190 200 210 220 230 240 410 420 430 440 450 460 pF1KB8 SSEVFTTFEQEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVK ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSEVFTTFKQEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVK 250 260 270 280 290 300 470 480 490 500 510 520 pF1KB8 IQRLEKLCRALQTERNDLNKRVQDLSAGGQGSLTDSGPERRPEGPGAQAPSSPRVTEAPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQRLEKLCRALQTERNDLNKRVQDLSAGGQGSLTDSGPERRPEGPGAQAPSSPRVTEAPC 310 320 330 340 350 360 530 540 pF1KB8 YPGAPSTEASGQTGPQEPTSARA ::::::::::::::::::::::: XP_011 YPGAPSTEASGQTGPQEPTSARA 370 380 >>XP_011539233 (OMIM: 608676) PREDICTED: alpha-taxilin i (386 aa) initn: 2228 init1: 2228 opt: 2228 Z-score: 1002.5 bits: 194.8 E(85289): 4.2e-49 Smith-Waterman score: 2228; 98.6% identity (98.9% similar) in 353 aa overlap (194-546:34-386) 170 180 190 200 210 220 pF1KB8 KAKGLGKEITLLMQTLNTLSTPEEKLAALCKKYAELLEEHRNSQKQMKLLQKKQSQLVQE :: :::::::::::::::::::::::: XP_011 RNPPRGIQTQKRSGRVTRSETETIEGHRRRKKPRVWLEEHRNSQKQMKLLQKKQSQLVQE 10 20 30 40 50 60 230 240 250 260 270 280 pF1KB8 KDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRAREEEEKRKEVTSHFQVTLND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRAREEEEKRKEVTSHFQVTLND 70 80 90 100 110 120 290 300 310 320 330 340 pF1KB8 IQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDKVFKHKDLQQQLVDAKLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDKVFKHKDLQQQLVDAKLQQ 130 140 150 160 170 180 350 360 370 380 390 400 pF1KB8 AQEMLKEAEERHQREKDFLLKEAVESQRMCELMKQQETHLKQQLALYTEKFEEFQNTLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQEMLKEAEERHQREKDFLLKEAVESQRMCELMKQQETHLKQQLALYTEKFEEFQNTLSK 190 200 210 220 230 240 410 420 430 440 450 460 pF1KB8 SSEVFTTFEQEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVK ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSEVFTTFKQEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVK 250 260 270 280 290 300 470 480 490 500 510 520 pF1KB8 IQRLEKLCRALQTERNDLNKRVQDLSAGGQGSLTDSGPERRPEGPGAQAPSSPRVTEAPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQRLEKLCRALQTERNDLNKRVQDLSAGGQGSLTDSGPERRPEGPGAQAPSSPRVTEAPC 310 320 330 340 350 360 530 540 pF1KB8 YPGAPSTEASGQTGPQEPTSARA ::::::::::::::::::::::: XP_011 YPGAPSTEASGQTGPQEPTSARA 370 380 >>NP_060830 (OMIM: 300677) gamma-taxilin isoform 1 [Homo (528 aa) initn: 1602 init1: 1602 opt: 1612 Z-score: 731.6 bits: 145.1 E(85289): 5.2e-34 Smith-Waterman score: 1631; 58.5% identity (80.8% similar) in 463 aa overlap (28-488:7-455) 10 20 30 40 50 pF1KB8 MKNQDKKNGAAQQSNPKSSPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPRKPE--GA :.:. : . : :.:: : ..::. :. NP_060 MATRVEEAARGRGGGAEEATEAGRGGRRRSPRQKFEIGT 10 20 30 60 70 80 90 100 110 pF1KB8 QARTAQSGALRDVSEELSRQLEDILSTYCVDNNQGGPGEDGAQGEPAEPEDAEKSRTYVA . ... : .. . : .:::. .: :: .. . : . ..:. :. NP_060 MEEAGICGLGVKADMLCNSQSNDILQHQ--GSNCGGTSNKHSLEEDEGSDFITENRNLVS 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB8 RNGEPEPTPVVNGEKEPSKGDPNTEEIRQSDEVGDRDHRRPQEKKKAKGLGKEITLLMQT :. .. .: : : : . :..: . ...: : ::::. ::::. NP_060 ------PAYCTQESREEIPGG----EARTDPPDGQQDSE--CNRNKEKTLGKEVLLLMQA 100 110 120 130 140 180 190 200 210 220 230 pF1KB8 LNTLSTPEEKLAALCKKYAELLEEHRNSQKQMKLLQKKQSQLVQEKDHLRGEHSKAVLAR :::::::::::::::::::.:::: :. :::::.:::::.:.:.:: ::..:::::.::: NP_060 LNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILAR 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB8 SKLESLCRELQRHNRSLKEEGVQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKL ::::::::::::::..::::..:.::::::.:::.:.:::.:::.:: :.:::. .:.:: NP_060 SKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLNEIQAQLEQHDIHNAKL 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB8 RQENMELAERLKKLIEQYELREEHIDKVFKHKDLQQQLVDAKLQQAQEMLKEAEERHQRE ::::.::.:.:::::::: :::::::::::::.::::::::::::. ...:::.:.:::: NP_060 RQENIELGEKLKKLIEQYALREEHIDKVFKHKELQQQLVDAKLQQTTQLIKEADEKHQRE 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB8 KDFLLKEAVESQRMCELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFEQEMEKM ..::::::.::.. : :::::..:::::.:: .::::::.:..::.:.::::.:::::: NP_060 REFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKM 330 340 350 360 370 380 420 430 440 450 460 470 pF1KB8 TKKIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVKIQRLEKLCRALQTER ::::::::::: ..:..::..:::::.::::::::::: ..::.:..::::::::::::: NP_060 TKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTER 390 400 410 420 430 440 480 490 500 510 520 530 pF1KB8 NDLNKRVQDLSAGGQGSLTDSGPERRPEGPGAQAPSSPRVTEAPCYPGAPSTEASGQTGP :.::..:. : NP_060 NELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPCTALDSHKELNTSSKRALGAHLEAEP 450 460 470 480 490 500 >>XP_011533807 (OMIM: 611438) PREDICTED: beta-taxilin is (684 aa) initn: 1563 init1: 1454 opt: 1501 Z-score: 681.6 bits: 136.2 E(85289): 3.2e-31 Smith-Waterman score: 1587; 52.6% identity (78.6% similar) in 504 aa overlap (3-506:4-479) 10 20 30 40 50 pF1KB8 MKNQDKKNGAAQQSNPKSSPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPRKPEGAQ :.... .: .::.: ::. .. ::. . .: : .: .: .: . XP_011 MEANHSEQLSAERQSTP---PGD-------SSSLPSHNG--LEKEDGQDSPTPVQPPEKE 10 20 30 40 60 70 80 90 100 110 pF1KB8 ARTAQSGALRDVSEELSRQLEDILSTYCVDNNQGGPGEDGAQGEPAEPEDAEKSRTYVAR : . :.::::.::::::..:: . . :..:. .::.::. . . XP_011 ASVHP-----DISEELNRQLEDIINTY--GSAASTAGKEGSARASEQPENAESPDN---E 50 60 70 80 90 120 130 140 150 160 170 pF1KB8 NGEPEPTPVVNGEKEPSKGDPNTEEIRQSDEVGDRDHRRPQEKKKAKGLGKEITLLMQTL .:. : : :.. ..:.: : . . :...... ::: :::::: .::::.: XP_011 DGDCEETTEEAGREPVASGEPPTVK----EPVSNKEQK--LEKKILKGLGKEANLLMQNL 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB8 NTLSTPEEKLAALCKKYAELLEEHRNSQKQMKLLQKKQSQLVQEKDHLRGEHSKAVLARS : :.:::::. : :::::::.:::. ::..::::::: :. .:::.:.::::.:.:::: XP_011 NKLQTPEEKFDFLFKKYAELLDEHRTEQKKLKLLQKKQVQIQKEKDQLQGEHSRAILARS 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB8 KLESLCRELQRHNRSLKEEGVQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLR :::::::::::::..::::..::::::::::::.::::: ::.::: :.::..::: :: XP_011 KLESLCRELQRHNKTLKEEALQRAREEEEKRKEITSHFQSTLTDIQGQIEQQSERNMKLC 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB8 QENMELAERLKKLIEQYELREEHIDKVFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREK ::: ::::.::..:.::::::::.::.:::..:::.::::::.:::::.:::::::.::: XP_011 QENTELAEKLKSIIDQYELREEHLDKIFKHRELQQKLVDAKLEQAQEMMKEAEERHKREK 280 290 300 310 320 330 360 370 380 390 400 410 pF1KB8 DFLLKEAVESQRMCELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFEQEMEKMT ..::..:.: . . ...:.::: :. ::.::. .:::::.::.::.:::.::.:::.: : XP_011 EYLLNQAAEWKLQAKVLKEQETVLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMDKTT 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB8 KKIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVKIQRLEKLCRALQTERN ::.:::::.:. ...:.:. :::::.: :::..: :: : . .:: :::.:::::: ::: XP_011 KKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYECFVMKIGRLENLCRALQEERN 400 410 420 430 440 450 480 490 500 510 520 530 pF1KB8 DLNKRVQDLSAGGQGSLTDSGPERRPEGPGAQAPSSPRVTEAPCYPGAPSTEASGQTGPQ .:.:...: . . . .. . ...:: XP_011 ELHKKIRDAEISEKDDQSQHNSDEEPESNVSVDQEIDAEEVNSVQTAVKNLATAFMIIHH 460 470 480 490 500 510 546 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:42:27 2016 done: Fri Nov 4 14:42:29 2016 Total Scan time: 11.280 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]