Result of FASTA (omim) for
pF1KB8699
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8699, 541 aa
1>>>pF1KB8699 541 - 541 aa - 541 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.5182+/-0.000419; mu= 7.6647+/- 0.026
mean_var=173.4573+/-35.070, 0's: 0 Z-trim(117.7): 170 B-trim: 436 in 2/49
Lambda= 0.097382
statistics sampled from 29734 (29971) to 29734 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.351), width: 16
Scan time: 11.380
The best scores are: opt bits E(85289)
NP_110443 (OMIM: 615125) ankyrin repeat domain-con ( 541) 3572 514.6 3e-145
XP_006710992 (OMIM: 615125) PREDICTED: ankyrin rep ( 503) 3286 474.4 3.6e-133
XP_005271291 (OMIM: 615125) PREDICTED: ankyrin rep ( 484) 3060 442.6 1.3e-123
XP_005271292 (OMIM: 615125) PREDICTED: ankyrin rep ( 451) 2845 412.4 1.5e-114
XP_016857902 (OMIM: 615125) PREDICTED: ankyrin rep ( 350) 2279 332.8 1.1e-90
XP_016857903 (OMIM: 615125) PREDICTED: ankyrin rep ( 272) 1766 260.6 4.4e-69
XP_016857905 (OMIM: 615125) PREDICTED: ankyrin rep ( 272) 1766 260.6 4.4e-69
XP_016857904 (OMIM: 615125) PREDICTED: ankyrin rep ( 272) 1766 260.6 4.4e-69
XP_016875647 (OMIM: 615123) PREDICTED: ankyrin rep ( 551) 532 87.5 1.1e-16
XP_016875651 (OMIM: 615123) PREDICTED: ankyrin rep ( 465) 522 86.1 2.7e-16
XP_011537240 (OMIM: 615123) PREDICTED: ankyrin rep ( 467) 522 86.1 2.7e-16
XP_016875646 (OMIM: 615123) PREDICTED: ankyrin rep ( 553) 522 86.1 3e-16
XP_005254039 (OMIM: 615123) PREDICTED: ankyrin rep ( 589) 522 86.1 3.2e-16
XP_005254038 (OMIM: 615123) PREDICTED: ankyrin rep ( 590) 522 86.1 3.2e-16
NP_149112 (OMIM: 615123) ankyrin repeat domain-con ( 590) 522 86.1 3.2e-16
XP_005254037 (OMIM: 615123) PREDICTED: ankyrin rep ( 591) 522 86.1 3.2e-16
XP_011522623 (OMIM: 615124) PREDICTED: ankyrin rep ( 343) 500 82.8 1.8e-15
XP_011522622 (OMIM: 615124) PREDICTED: ankyrin rep ( 343) 500 82.8 1.8e-15
XP_005257977 (OMIM: 615124) PREDICTED: ankyrin rep ( 637) 503 83.5 2.1e-15
NP_689558 (OMIM: 615124) ankyrin repeat domain-con ( 626) 501 83.2 2.6e-15
NP_997237 (OMIM: 615126) ankyrin repeat domain-con ( 605) 491 81.8 6.6e-15
XP_011543287 (OMIM: 615126) PREDICTED: ankyrin rep ( 654) 491 81.8 7e-15
XP_011522621 (OMIM: 615124) PREDICTED: ankyrin rep ( 629) 473 79.3 3.9e-14
XP_016875652 (OMIM: 615123) PREDICTED: ankyrin rep ( 425) 372 64.9 5.5e-10
XP_011537239 (OMIM: 615123) PREDICTED: ankyrin rep ( 543) 333 59.6 2.9e-08
XP_016875650 (OMIM: 615123) PREDICTED: ankyrin rep ( 501) 292 53.8 1.5e-06
XP_016875648 (OMIM: 615123) PREDICTED: ankyrin rep ( 502) 292 53.8 1.5e-06
XP_016875649 (OMIM: 615123) PREDICTED: ankyrin rep ( 502) 292 53.8 1.5e-06
XP_005254041 (OMIM: 615123) PREDICTED: ankyrin rep ( 503) 292 53.8 1.5e-06
XP_011543288 (OMIM: 615126) PREDICTED: ankyrin rep ( 567) 279 52.0 5.8e-06
XP_011543289 (OMIM: 615126) PREDICTED: ankyrin rep ( 567) 279 52.0 5.8e-06
XP_016879665 (OMIM: 615124) PREDICTED: ankyrin rep ( 505) 244 47.0 0.00016
XP_016879664 (OMIM: 615124) PREDICTED: ankyrin rep ( 505) 244 47.0 0.00016
XP_016879663 (OMIM: 615124) PREDICTED: ankyrin rep ( 505) 244 47.0 0.00016
XP_011543290 (OMIM: 615126) PREDICTED: ankyrin rep ( 350) 215 42.8 0.0021
>>NP_110443 (OMIM: 615125) ankyrin repeat domain-contain (541 aa)
initn: 3572 init1: 3572 opt: 3572 Z-score: 2728.6 bits: 514.6 E(85289): 3e-145
Smith-Waterman score: 3572; 99.1% identity (99.4% similar) in 541 aa overlap (1-541:1-541)
10 20 30 40 50 60
pF1KB8 MTGEKIRSLRRDHKPSKEEGDLLEPGDEEAAAALGGTFTRSRIGKGGKACHKTFSNHHHR
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_110 MTGEKIRSLRRDHKPSKEEGDLLEPGDEEAAAALGGTFTRSRIGKGGKACHKIFSNHHHR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LQLKAAPASSNPPGAPALPLHNSSVTANSQSPALLAGTNPVAVVADGGSCPAHYPVHECV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 LQLKAAPASSNPPGAPALPLHNSSVTANSQSPALLAGTNPVAVVADGGSCPAHYPVHECV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FKGDVRRLSSLIRTHNIGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 FKGDVRRLSSLIRTHNIGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LAEAISYGDRQMITALLRKLKQQSRESVEEKRPRLLKALKELGDFYLELHWDFQSWVPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 LAEAISYGDRQMITALLRKLKQQSRESVEEKRPRLLKALKELGDFYLELHWDFQSWVPLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGGLSFIFNGDAAPSESFVVLDNEQKV
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_110 SRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFNGDAAPSESFVVLDNEQKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 YQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTGRVGNFLAD
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
NP_110 YQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTERVGNFLAD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 FYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQNFEPIRRQSLSPPPQNTI
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
NP_110 FYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQNFEPIRRQSLTPPPQNTI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 TWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPLGIELLLNVLEVVAPFKHFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 TWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPLGIELLLNVLEVVAPFKHFN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 KLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFQYDEFDGSIFTIPDDYKEDPSRFPD
:::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
NP_110 KLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFRYDEFDGSIFTIPDDYKEDPSRFPD
490 500 510 520 530 540
pF1KB8 L
:
NP_110 L
>>XP_006710992 (OMIM: 615125) PREDICTED: ankyrin repeat (503 aa)
initn: 3310 init1: 3286 opt: 3286 Z-score: 2511.8 bits: 474.4 E(85289): 3.6e-133
Smith-Waterman score: 3286; 98.4% identity (99.0% similar) in 502 aa overlap (1-502:1-502)
10 20 30 40 50 60
pF1KB8 MTGEKIRSLRRDHKPSKEEGDLLEPGDEEAAAALGGTFTRSRIGKGGKACHKTFSNHHHR
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_006 MTGEKIRSLRRDHKPSKEEGDLLEPGDEEAAAALGGTFTRSRIGKGGKACHKIFSNHHHR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LQLKAAPASSNPPGAPALPLHNSSVTANSQSPALLAGTNPVAVVADGGSCPAHYPVHECV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQLKAAPASSNPPGAPALPLHNSSVTANSQSPALLAGTNPVAVVADGGSCPAHYPVHECV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FKGDVRRLSSLIRTHNIGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FKGDVRRLSSLIRTHNIGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LAEAISYGDRQMITALLRKLKQQSRESVEEKRPRLLKALKELGDFYLELHWDFQSWVPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LAEAISYGDRQMITALLRKLKQQSRESVEEKRPRLLKALKELGDFYLELHWDFQSWVPLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGGLSFIFNGDAAPSESFVVLDNEQKV
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_006 SRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFNGDAAPSESFVVLDNEQKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 YQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTGRVGNFLAD
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_006 YQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTERVGNFLAD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 FYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQNFEPIRRQSLSPPPQNTI
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_006 FYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQNFEPIRRQSLTPPPQNTI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 TWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPLGIELLLNVLEVVAPFKHFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPLGIELLLNVLEVVAPFKHFN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 KLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFQYDEFDGSIFTIPDDYKEDPSRFPD
:::::::::::::::::: . .
XP_006 KLREFVQMKLPPGFPVKLGVSIR
490 500
>>XP_005271291 (OMIM: 615125) PREDICTED: ankyrin repeat (484 aa)
initn: 3084 init1: 3060 opt: 3060 Z-score: 2340.5 bits: 442.6 E(85289): 1.3e-123
Smith-Waterman score: 3060; 98.5% identity (98.7% similar) in 469 aa overlap (1-469:1-469)
10 20 30 40 50 60
pF1KB8 MTGEKIRSLRRDHKPSKEEGDLLEPGDEEAAAALGGTFTRSRIGKGGKACHKTFSNHHHR
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_005 MTGEKIRSLRRDHKPSKEEGDLLEPGDEEAAAALGGTFTRSRIGKGGKACHKIFSNHHHR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LQLKAAPASSNPPGAPALPLHNSSVTANSQSPALLAGTNPVAVVADGGSCPAHYPVHECV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQLKAAPASSNPPGAPALPLHNSSVTANSQSPALLAGTNPVAVVADGGSCPAHYPVHECV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FKGDVRRLSSLIRTHNIGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKGDVRRLSSLIRTHNIGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LAEAISYGDRQMITALLRKLKQQSRESVEEKRPRLLKALKELGDFYLELHWDFQSWVPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAEAISYGDRQMITALLRKLKQQSRESVEEKRPRLLKALKELGDFYLELHWDFQSWVPLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGGLSFIFNGDAAPSESFVVLDNEQKV
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_005 SRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFNGDAAPSESFVVLDNEQKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 YQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTGRVGNFLAD
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_005 YQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTERVGNFLAD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 FYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQNFEPIRRQSLSPPPQNTI
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_005 FYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQNFEPIRRQSLTPPPQNTI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 TWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPLGIELLLNVLEVVAPFKHFN
::::::::::::::::::::::::::::::::::::::::::::: :
XP_005 TWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPLGIELYTCVSHNHSHCDFSG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 KLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFQYDEFDGSIFTIPDDYKEDPSRFPD
XP_005 VSIR
>>XP_005271292 (OMIM: 615125) PREDICTED: ankyrin repeat (451 aa)
initn: 2845 init1: 2845 opt: 2845 Z-score: 2177.6 bits: 412.4 E(85289): 1.5e-114
Smith-Waterman score: 2845; 99.1% identity (99.3% similar) in 432 aa overlap (1-432:1-432)
10 20 30 40 50 60
pF1KB8 MTGEKIRSLRRDHKPSKEEGDLLEPGDEEAAAALGGTFTRSRIGKGGKACHKTFSNHHHR
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_005 MTGEKIRSLRRDHKPSKEEGDLLEPGDEEAAAALGGTFTRSRIGKGGKACHKIFSNHHHR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LQLKAAPASSNPPGAPALPLHNSSVTANSQSPALLAGTNPVAVVADGGSCPAHYPVHECV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQLKAAPASSNPPGAPALPLHNSSVTANSQSPALLAGTNPVAVVADGGSCPAHYPVHECV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FKGDVRRLSSLIRTHNIGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKGDVRRLSSLIRTHNIGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LAEAISYGDRQMITALLRKLKQQSRESVEEKRPRLLKALKELGDFYLELHWDFQSWVPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAEAISYGDRQMITALLRKLKQQSRESVEEKRPRLLKALKELGDFYLELHWDFQSWVPLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGGLSFIFNGDAAPSESFVVLDNEQKV
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_005 SRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFNGDAAPSESFVVLDNEQKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 YQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTGRVGNFLAD
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_005 YQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTERVGNFLAD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 FYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQNFEPIRRQSLSPPPQNTI
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_005 FYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQNFEPIRRQSLTPPPQNTI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 TWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPLGIELLLNVLEVVAPFKHFN
::::::::::::
XP_005 TWEEYISAENGKYTCVSHNHSHCDFSGVSIR
430 440 450
>>XP_016857902 (OMIM: 615125) PREDICTED: ankyrin repeat (350 aa)
initn: 2279 init1: 2279 opt: 2279 Z-score: 1749.3 bits: 332.8 E(85289): 1.1e-90
Smith-Waterman score: 2279; 98.9% identity (99.4% similar) in 350 aa overlap (192-541:1-350)
170 180 190 200 210 220
pF1KB8 LLLAHNAPVKVKNAQGWSPLAEAISYGDRQMITALLRKLKQQSRESVEEKRPRLLKALKE
::::::::::::::::::::::::::::::
XP_016 MITALLRKLKQQSRESVEEKRPRLLKALKE
10 20 30
230 240 250 260 270 280
pF1KB8 LGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGGLSFIF
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_016 LGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIF
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB8 NGDAAPSESFVVLDNEQKVYQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGDAAPSESFVVLDNEQKVYQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQ
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB8 TGWLFREDKTGRVGNFLADFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIME
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGWLFREDKTERVGNFLADFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIME
160 170 180 190 200 210
410 420 430 440 450 460
pF1KB8 QNFEPIRRQSLSPPPQNTITWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPL
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNFEPIRRQSLTPPPQNTITWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPL
220 230 240 250 260 270
470 480 490 500 510 520
pF1KB8 GIELLLNVLEVVAPFKHFNKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFQYDEFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
XP_016 GIELLLNVLEVVAPFKHFNKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFRYDEFD
280 290 300 310 320 330
530 540
pF1KB8 GSIFTIPDDYKEDPSRFPDL
::::::::::::::::::::
XP_016 GSIFTIPDDYKEDPSRFPDL
340 350
>>XP_016857903 (OMIM: 615125) PREDICTED: ankyrin repeat (272 aa)
initn: 1766 init1: 1766 opt: 1766 Z-score: 1361.2 bits: 260.6 E(85289): 4.4e-69
Smith-Waterman score: 1766; 98.5% identity (99.3% similar) in 272 aa overlap (270-541:1-272)
240 250 260 270 280 290
pF1KB8 LSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGGLSFIFNGDAAPSESFVVLDNEQK
:::::: :::::::::::::::::::::::
XP_016 MKCQRGDLSFIFNGDAAPSESFVVLDNEQK
10 20 30
300 310 320 330 340 350
pF1KB8 VYQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTGRVGNFLA
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 VYQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTERVGNFLA
40 50 60 70 80 90
360 370 380 390 400 410
pF1KB8 DFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQNFEPIRRQSLSPPPQNT
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
XP_016 DFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQNFEPIRRQSLTPPPQNT
100 110 120 130 140 150
420 430 440 450 460 470
pF1KB8 ITWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPLGIELLLNVLEVVAPFKHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPLGIELLLNVLEVVAPFKHF
160 170 180 190 200 210
480 490 500 510 520 530
pF1KB8 NKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFQYDEFDGSIFTIPDDYKEDPSRFP
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_016 NKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFRYDEFDGSIFTIPDDYKEDPSRFP
220 230 240 250 260 270
540
pF1KB8 DL
::
XP_016 DL
>>XP_016857905 (OMIM: 615125) PREDICTED: ankyrin repeat (272 aa)
initn: 1766 init1: 1766 opt: 1766 Z-score: 1361.2 bits: 260.6 E(85289): 4.4e-69
Smith-Waterman score: 1766; 98.5% identity (99.3% similar) in 272 aa overlap (270-541:1-272)
240 250 260 270 280 290
pF1KB8 LSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGGLSFIFNGDAAPSESFVVLDNEQK
:::::: :::::::::::::::::::::::
XP_016 MKCQRGDLSFIFNGDAAPSESFVVLDNEQK
10 20 30
300 310 320 330 340 350
pF1KB8 VYQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTGRVGNFLA
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 VYQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTERVGNFLA
40 50 60 70 80 90
360 370 380 390 400 410
pF1KB8 DFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQNFEPIRRQSLSPPPQNT
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
XP_016 DFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQNFEPIRRQSLTPPPQNT
100 110 120 130 140 150
420 430 440 450 460 470
pF1KB8 ITWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPLGIELLLNVLEVVAPFKHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPLGIELLLNVLEVVAPFKHF
160 170 180 190 200 210
480 490 500 510 520 530
pF1KB8 NKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFQYDEFDGSIFTIPDDYKEDPSRFP
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_016 NKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFRYDEFDGSIFTIPDDYKEDPSRFP
220 230 240 250 260 270
540
pF1KB8 DL
::
XP_016 DL
>>XP_016857904 (OMIM: 615125) PREDICTED: ankyrin repeat (272 aa)
initn: 1766 init1: 1766 opt: 1766 Z-score: 1361.2 bits: 260.6 E(85289): 4.4e-69
Smith-Waterman score: 1766; 98.5% identity (99.3% similar) in 272 aa overlap (270-541:1-272)
240 250 260 270 280 290
pF1KB8 LSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGGLSFIFNGDAAPSESFVVLDNEQK
:::::: :::::::::::::::::::::::
XP_016 MKCQRGDLSFIFNGDAAPSESFVVLDNEQK
10 20 30
300 310 320 330 340 350
pF1KB8 VYQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTGRVGNFLA
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 VYQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTERVGNFLA
40 50 60 70 80 90
360 370 380 390 400 410
pF1KB8 DFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQNFEPIRRQSLSPPPQNT
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
XP_016 DFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQNFEPIRRQSLTPPPQNT
100 110 120 130 140 150
420 430 440 450 460 470
pF1KB8 ITWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPLGIELLLNVLEVVAPFKHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPLGIELLLNVLEVVAPFKHF
160 170 180 190 200 210
480 490 500 510 520 530
pF1KB8 NKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFQYDEFDGSIFTIPDDYKEDPSRFP
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_016 NKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFRYDEFDGSIFTIPDDYKEDPSRFP
220 230 240 250 260 270
540
pF1KB8 DL
::
XP_016 DL
>>XP_016875647 (OMIM: 615123) PREDICTED: ankyrin repeat (551 aa)
initn: 654 init1: 513 opt: 532 Z-score: 420.2 bits: 87.5 E(85289): 1.1e-16
Smith-Waterman score: 812; 35.4% identity (64.6% similar) in 452 aa overlap (109-537:4-437)
80 90 100 110 120 130
pF1KB8 PLHNSSVTANSQSPALLAGTNPVAVVADGGSCPA--HYPVHECVFKGDVRRLSSLIRTHN
.: : :::.: :.:.: :.: . .. .:
XP_016 MSSACDAGDHYPLHLLVWKNDYRQLEKELQGQN
10 20 30
140 150 160 170 180 190
pF1KB8 IGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSPLAEAISYGDRQMITAL
. : .: : ::::: ::. : :..:: :.: : .: :::. : ::.: :: .:. ..
XP_016 VEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYTV
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB8 LRKLKQQSRESVEEKRPRLLKALKELGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGI
:.. .. . : :.::. . : :::....:.: :::::.::: :.:.:.:.:.:
XP_016 LQHRDYHNTSMALEGVPELLQKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGA
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB8 NIRLDTTLIDFTDMKCQRGGLSFIFNGDAAPSESFVVLDNEQKVYQRIHHEESEMET---
..:.: ::. : .:. :: ::::.:. .: . : ... : . .:::
XP_016 KLRVDITLLGFENMSWIRGRRSFIFKGEDNWAELMEVNHDDKVVTTERFDLSQEMERLTL
160 170 180 190 200 210
320 330 340 350 360
pF1KB8 ------EEEVDILMSSDIYSATLSTKSISFTRAQTG-WLFREDKTGRVGNFLADFYLVNG
.::. ..: . ...:.::.:.: :...: : .: ::. :... : : ::.
XP_016 DLMKPKSREVERRLTSPVINTSLDTKNIAFERTKSGFWGWRTDKAEVVNGYEAKVYTVNN
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB8 LVLESRKRREHLSEEDILR--NKAIMESLSKGGNIMEQNFEP---IRRQSLSPPPQNTIT
. . .. : :::.::. : .. .::: :.. :..: . . . ..::
XP_016 VNVITKIRTEHLTEEEKKRYKDRNPLESLL--GTV-EHQFGAQGDLTTECATANNPTAIT
280 290 300 310 320 330
430 440 450 460 470
pF1KB8 WEEYISAE-NGKAPHLGR--ELVCKESKKTFKATIAMSQEFPLG-IELLLNVLEVVAPFK
.::.. : . : .:: ::. . .: ::: . : .::::. .: .. .....: .
XP_016 PDEYFNEEFDLKDRDIGRPKELTIRTQK--FKAMLWMCEEFPLSLVEQVIPIIDLMARTS
340 350 360 370 380
480 490 500 510 520 530
pF1KB8 -HFNKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFQYDEFDGSIFTIPDDYK-EDP
:: .::.:.....::::::: :.. .: .:. :. :.: ::..: .:
XP_016 AHFARLRDFIKLEFPPGFPVK--------IASHIT--NFEVDQ---SVFEIPESYYVQDN
390 400 410 420 430
540
pF1KB8 SRFPDL
.:
XP_016 GRNVHLQDEDYEIMQFAIQQSLLESSRSQELSGPASNGGISQTNTYDAQYERAIQESLLT
440 450 460 470 480 490
>>XP_016875651 (OMIM: 615123) PREDICTED: ankyrin repeat (465 aa)
initn: 701 init1: 513 opt: 522 Z-score: 413.6 bits: 86.1 E(85289): 2.7e-16
Smith-Waterman score: 843; 36.4% identity (66.4% similar) in 426 aa overlap (109-512:4-424)
80 90 100 110 120 130
pF1KB8 PLHNSSVTANSQSPALLAGTNPVAVVADGGSCPA--HYPVHECVFKGDVRRLSSLIRTHN
.: : :::.: :.:.: :.: . .. .:
XP_016 MSSACDAGDHYPLHLLVWKNDYRQLEKELQGQN
10 20 30
140 150 160 170 180 190
pF1KB8 IGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSPLAEAISYGDRQMITAL
. : .: : ::::: ::. : :..:: :.: : .: :::. : ::.: :: .:. ..
XP_016 VEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYTV
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB8 LRKLKQQSRESVEEKRPRLLKALKELGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGI
:.. .. . : :.::. . : :::....:.: :::::.::: :.:.:.:.:.:
XP_016 LQHRDYHNTSMALEGVPELLQKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGA
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB8 NIRLDTTLIDFTDMKCQRGGLSFIFNGDAAPSESFVVLDNEQKVYQRIHHEESEMET---
..:.: ::. : .:. :: ::::.:. .: . : ... : . .:::
XP_016 KLRVDITLLGFENMSWIRGRRSFIFKGEDNWAELMEVNHDDKVVTTERFDLSQEMERLTL
160 170 180 190 200 210
320 330 340 350 360
pF1KB8 ------EEEVDILMSSDIYSATLSTKSISFTRAQTG-WLFREDKTGRVGNFLADFYLVNG
.::. ..: . ...:.::.:.: :...: : .: ::. :... : : ::.
XP_016 DLMKPKSREVERRLTSPVINTSLDTKNIAFERTKSGFWGWRTDKAEVVNGYEAKVYTVNN
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB8 LVLESRKRREHLSEEDILR--NKAIMESLSKGGNIMEQNFEP---IRRQSLSPPPQNTIT
. . .. : :::.::. : .. .::: :.. :..: . . . ..::
XP_016 VNVITKIRTEHLTEEEKKRYKDRNPLESLL--GTV-EHQFGAQGDLTTECATANNPTAIT
280 290 300 310 320 330
430 440 450 460 470
pF1KB8 WEEYISAE-NGKAPHLGR--ELVCKESKKTFKATIAMSQEFPLG-IELLLNVLEVVAPFK
.::.. : . : .:: ::. . .: ::: . : .::::. .: .. .....: .
XP_016 PDEYFNEEFDLKDRDIGRPKELTIRTQK--FKAMLWMCEEFPLSLVEQVIPIIDLMARTS
340 350 360 370 380
480 490 500 510 520 530
pF1KB8 -HFNKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFQYDEFDGSIFTIPDDYKEDPS
:: .::.:.....:::::::..::.: ...: .::
XP_016 AHFARLRDFIKLEFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEESVSQNVEGTQADS
390 400 410 420 430 440
540
pF1KB8 RFPDL
XP_016 GTFRTSFEWRDQPDKHL
450 460
541 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:43:47 2016 done: Fri Nov 4 14:43:48 2016
Total Scan time: 11.380 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]