FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8703, 574 aa 1>>>pF1KB8703 574 - 574 aa - 574 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.9371+/-0.000326; mu= 4.7782+/- 0.020 mean_var=261.7805+/-52.269, 0's: 0 Z-trim(124.3): 30 B-trim: 154 in 1/57 Lambda= 0.079269 statistics sampled from 45740 (45771) to 45740 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.82), E-opt: 0.2 (0.537), width: 16 Scan time: 13.420 The best scores are: opt bits E(85289) NP_056485 (OMIM: 612844) sentrin-specific protease ( 574) 4035 474.5 4.2e-133 XP_011510846 (OMIM: 612845) PREDICTED: sentrin-spe ( 755) 1040 132.1 6.5e-30 NP_689912 (OMIM: 612845) sentrin-specific protease ( 755) 1040 132.1 6.5e-30 XP_005269367 (OMIM: 612845) PREDICTED: sentrin-spe ( 727) 702 93.4 2.7e-18 XP_016874729 (OMIM: 612157) PREDICTED: sentrin-spe ( 432) 559 76.8 1.6e-13 XP_016874727 (OMIM: 612157) PREDICTED: sentrin-spe ( 445) 559 76.8 1.6e-13 XP_006719425 (OMIM: 612157) PREDICTED: sentrin-spe ( 445) 559 76.8 1.6e-13 XP_016874728 (OMIM: 612157) PREDICTED: sentrin-spe ( 445) 559 76.8 1.6e-13 XP_016874726 (OMIM: 612157) PREDICTED: sentrin-spe ( 631) 559 77.0 2.1e-13 XP_016874725 (OMIM: 612157) PREDICTED: sentrin-spe ( 631) 559 77.0 2.1e-13 XP_016874724 (OMIM: 612157) PREDICTED: sentrin-spe ( 637) 559 77.0 2.1e-13 XP_016874723 (OMIM: 612157) PREDICTED: sentrin-spe ( 637) 559 77.0 2.1e-13 XP_016874722 (OMIM: 612157) PREDICTED: sentrin-spe ( 637) 559 77.0 2.1e-13 NP_001254523 (OMIM: 612157) sentrin-specific prote ( 644) 559 77.0 2.1e-13 NP_001254524 (OMIM: 612157) sentrin-specific prote ( 644) 559 77.0 2.1e-13 XP_011536547 (OMIM: 612157) PREDICTED: sentrin-spe ( 660) 559 77.0 2.1e-13 XP_011536546 (OMIM: 612157) PREDICTED: sentrin-spe ( 663) 559 77.0 2.1e-13 XP_016874720 (OMIM: 612157) PREDICTED: sentrin-spe ( 675) 559 77.0 2.2e-13 XP_016874721 (OMIM: 612157) PREDICTED: sentrin-spe ( 675) 559 77.0 2.2e-13 XP_006719424 (OMIM: 612157) PREDICTED: sentrin-spe ( 676) 559 77.0 2.2e-13 XP_016874719 (OMIM: 612157) PREDICTED: sentrin-spe ( 694) 559 77.0 2.2e-13 XP_016874718 (OMIM: 612157) PREDICTED: sentrin-spe ( 707) 559 77.0 2.2e-13 XP_011510847 (OMIM: 612845) PREDICTED: sentrin-spe ( 643) 529 73.6 2.3e-12 XP_005269369 (OMIM: 612845) PREDICTED: sentrin-spe ( 681) 524 73.0 3.5e-12 XP_016861359 (OMIM: 612845) PREDICTED: sentrin-spe ( 709) 524 73.0 3.6e-12 NP_001294974 (OMIM: 612845) sentrin-specific prote ( 709) 524 73.0 3.6e-12 XP_005247748 (OMIM: 608261) PREDICTED: sentrin-spe ( 474) 494 69.4 2.9e-11 NP_067640 (OMIM: 608261) sentrin-specific protease ( 589) 494 69.5 3.4e-11 XP_016862462 (OMIM: 608261) PREDICTED: sentrin-spe ( 430) 425 61.5 6.4e-09 XP_005247747 (OMIM: 608261) PREDICTED: sentrin-spe ( 545) 425 61.6 7.6e-09 >>NP_056485 (OMIM: 612844) sentrin-specific protease 3 [ (574 aa) initn: 4035 init1: 4035 opt: 4035 Z-score: 2510.7 bits: 474.5 E(85289): 4.2e-133 Smith-Waterman score: 4035; 99.8% identity (99.8% similar) in 574 aa overlap (1-574:1-574) 10 20 30 40 50 60 pF1KB8 MKETIQGTGSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MKETIQGTGSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RRLPVPRPSFDASASEEEEEEEEEVDEDEEEEVAAWRLPPRWSQLGTSQRPRPSRPTHRK :::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::: NP_056 RRLPVPRPSFDASASEEEEEEEEEEDEDEEEEVAAWRLPPRWSQLGTSQRPRPSRPTHRK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRGLAHPKNHLSPQQGGATPQVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRGLAHPKNHLSPQQGGATPQVP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SPCCRFDSPRGPPPPRLGLLGALMAEDGVRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SPCCRFDSPRGPPPPRLGLLGALMAEDGVRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LSCTLPNGFGGQSGPEGERSLAPPDASILISNVCSIGDHVAQELFQGSDLGMAEEAERPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LSCTLPNGFGGQSGPEGERSLAPPDASILISNVCSIGDHVAQELFQGSDLGMAEEAERPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 EKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKGLV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 KVHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KVHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 FDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYC 490 500 510 520 530 540 550 560 570 pF1KB8 KHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV :::::::::::::::::::::::::::::::::: NP_056 KHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV 550 560 570 >>XP_011510846 (OMIM: 612845) PREDICTED: sentrin-specifi (755 aa) initn: 1041 init1: 887 opt: 1040 Z-score: 658.1 bits: 132.1 E(85289): 6.5e-30 Smith-Waterman score: 1040; 53.5% identity (79.2% similar) in 284 aa overlap (291-572:475-753) 270 280 290 300 310 pF1KB8 LAPPDASILISNVCSIGDHVAQELFQGSDLGMAEEAERPGEKAGQH-SPLREEHVT-CVQ :. : . : : .:. ::. .:... :.. XP_011 DGSLKQSILSSELLDHPYCKSPLEAPLVCSGLKLENQVGGGKNSQKASPVDDEQLSVCLS 450 460 470 480 490 500 320 330 340 350 360 370 pF1KB8 SILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKGLVLQLIQSYQRMPGNAMVRG ..::: .. ::::.::: ::. .:.:.:...:: .:: .. . : .:. . . XP_011 GFLDEVMKKYGSLVPLSEKEVLGRLKDVFNEDFS--NRKPFINREITNYRARHQKC---N 510 520 530 540 550 380 390 400 410 420 430 pF1KB8 FRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEKVHFFNSFFYDKLRTKGY ::. :..:.: ::::.:: :::::::::.::::.:.::.::.:::::::::. .: :::: XP_011 FRIFYNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDAVPDKVHFFNSFFHRQLVTKGY 560 570 580 590 600 610 440 450 460 470 480 490 pF1KB8 DGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKY .:::::::.::.:.: :::::::::::::::.: . : :...::: . : ..: :: XP_011 NGVKRWTKKVDLFKKSLLLIPIHLEVHWSLITVTLSNRIISFYDSQGIHFKFCVENIRKY 620 630 640 650 660 670 500 510 520 530 540 550 pF1KB8 LQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPK : .:: .:.: .: :::. . .:.::::::.::::::: ::: :::.:.:.:::. XP_011 LLTEAREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQYCKCLALEQPFQFSQEDMPR 680 690 700 710 720 730 560 570 pF1KB8 LRRQIYKELCHCKLTV .:..::::::.:.: XP_011 VRKRIYKELCECRLMD 740 750 >>NP_689912 (OMIM: 612845) sentrin-specific protease 5 i (755 aa) initn: 1041 init1: 887 opt: 1040 Z-score: 658.1 bits: 132.1 E(85289): 6.5e-30 Smith-Waterman score: 1040; 53.5% identity (79.2% similar) in 284 aa overlap (291-572:475-753) 270 280 290 300 310 pF1KB8 LAPPDASILISNVCSIGDHVAQELFQGSDLGMAEEAERPGEKAGQH-SPLREEHVT-CVQ :. : . : : .:. ::. .:... :.. NP_689 DGSLKQSILSSELLDHPYCKSPLEAPLVCSGLKLENQVGGGKNSQKASPVDDEQLSVCLS 450 460 470 480 490 500 320 330 340 350 360 370 pF1KB8 SILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKGLVLQLIQSYQRMPGNAMVRG ..::: .. ::::.::: ::. .:.:.:...:: .:: .. . : .:. . . NP_689 GFLDEVMKKYGSLVPLSEKEVLGRLKDVFNEDFS--NRKPFINREITNYRARHQKC---N 510 520 530 540 550 380 390 400 410 420 430 pF1KB8 FRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEKVHFFNSFFYDKLRTKGY ::. :..:.: ::::.:: :::::::::.::::.:.::.::.:::::::::. .: :::: NP_689 FRIFYNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDAVPDKVHFFNSFFHRQLVTKGY 560 570 580 590 600 610 440 450 460 470 480 490 pF1KB8 DGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKY .:::::::.::.:.: :::::::::::::::.: . : :...::: . : ..: :: NP_689 NGVKRWTKKVDLFKKSLLLIPIHLEVHWSLITVTLSNRIISFYDSQGIHFKFCVENIRKY 620 630 640 650 660 670 500 510 520 530 540 550 pF1KB8 LQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPK : .:: .:.: .: :::. . .:.::::::.::::::: ::: :::.:.:.:::. NP_689 LLTEAREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQYCKCLALEQPFQFSQEDMPR 680 690 700 710 720 730 560 570 pF1KB8 LRRQIYKELCHCKLTV .:..::::::.:.: NP_689 VRKRIYKELCECRLMD 740 750 >>XP_005269367 (OMIM: 612845) PREDICTED: sentrin-specifi (727 aa) initn: 946 init1: 546 opt: 702 Z-score: 449.4 bits: 93.4 E(85289): 2.7e-18 Smith-Waterman score: 903; 49.6% identity (72.9% similar) in 284 aa overlap (291-572:475-725) 270 280 290 300 310 pF1KB8 LAPPDASILISNVCSIGDHVAQELFQGSDLGMAEEAERPGEKAGQH-SPLREEHVT-CVQ :. : . : : .:. ::. .:... :.. XP_005 DGSLKQSILSSELLDHPYCKSPLEAPLVCSGLKLENQVGGGKNSQKASPVDDEQLSVCLS 450 460 470 480 490 500 320 330 340 350 360 370 pF1KB8 SILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKGLVLQLIQSYQRMPGNAMVRG ..::: .. ::::.::: ::. .:.:.:...:: .:: .. . : .:. . . XP_005 GFLDEVMKKYGSLVPLSEKEVLGRLKDVFNEDFS--NRKPFINREITNYRARHQKC---N 510 520 530 540 550 380 390 400 410 420 430 pF1KB8 FRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEKVHFFNSFFYDKLRTKGY ::. :..:.: ::::.:: :::::::::.::::.:.::.::.:::::::::. .: :::: XP_005 FRIFYNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDAVPDKVHFFNSFFHRQLVTKGY 560 570 580 590 600 610 440 450 460 470 480 490 pF1KB8 DGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKY .:::::::.::.:.: :::::::::::::::.: . : :...::: . : . : . XP_005 NGVKRWTKKVDLFKKSLLLIPIHLEVHWSLITVTLSNRIISFYDSQGIHFKFCVECIPQ- 620 630 640 650 660 670 500 510 520 530 540 550 pF1KB8 LQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPK :.::::::.::::::: ::: :::.:.:.:::. XP_005 ---------------------------QKNDSDCGVFVLQYCKCLALEQPFQFSQEDMPR 680 690 700 710 560 570 pF1KB8 LRRQIYKELCHCKLTV .:..::::::.:.: XP_005 VRKRIYKELCECRLMD 720 >>XP_016874729 (OMIM: 612157) PREDICTED: sentrin-specifi (432 aa) initn: 461 init1: 331 opt: 559 Z-score: 363.9 bits: 76.8 E(85289): 1.6e-13 Smith-Waterman score: 562; 37.0% identity (63.7% similar) in 273 aa overlap (308-572:181-431) 280 290 300 310 320 330 pF1KB8 DHVAQELFQGSDLGMAEEAERPGEKAGQHSPLREE-HVTCVQSILDEFLQTYGSLIPLST ::..: :: :: : : . : XP_016 QKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQET-----QKKGHKLTDSE 160 170 180 190 200 340 350 360 370 380 390 pF1KB8 DEVVEKLEDIFQQEFSTPSRKGLVLQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTL :: : :.. ..:... :.: ... ..::.. :. :. :: XP_016 DEFPEITEEM-EKEIKNVFRNG-----------NQDEVLSEAFRLTITRK-----DIQTL 210 220 230 240 400 410 420 430 440 450 pF1KB8 YGQNWLNDQVMNMYGDLVMDTVPEK----VHFFNSFFYDKLRTKGYDGVKRWTKNVDIFN :::::...:.: ...:. :: :: ::.::. ::.: ::..::::::.::.:. XP_016 NHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFS 250 260 270 280 290 300 460 470 480 490 500 510 pF1KB8 KELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFH ..::.:::: ::: : :: :...:::.::. .: . . . .::. :.. : : .: XP_016 VDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFD 310 320 330 340 350 360 520 530 540 550 560 pF1KB8 -QGWKGYFK--MNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCH .::. . : ... .: : :::: :. .: .. ..:..:::: :: .:... :. : XP_016 TNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILH 370 380 390 400 410 420 570 pF1KB8 CKLTV :: XP_016 RKLL 430 >>XP_016874727 (OMIM: 612157) PREDICTED: sentrin-specifi (445 aa) initn: 461 init1: 331 opt: 559 Z-score: 363.7 bits: 76.8 E(85289): 1.6e-13 Smith-Waterman score: 562; 37.0% identity (63.7% similar) in 273 aa overlap (308-572:194-444) 280 290 300 310 320 330 pF1KB8 DHVAQELFQGSDLGMAEEAERPGEKAGQHSPLREE-HVTCVQSILDEFLQTYGSLIPLST ::..: :: :: : : . : XP_016 QKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQET-----QKKGHKLTDSE 170 180 190 200 210 340 350 360 370 380 390 pF1KB8 DEVVEKLEDIFQQEFSTPSRKGLVLQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTL :: : :.. ..:... :.: ... ..::.. :. :. :: XP_016 DEFPEITEEM-EKEIKNVFRNG-----------NQDEVLSEAFRLTITRK-----DIQTL 220 230 240 250 260 400 410 420 430 440 450 pF1KB8 YGQNWLNDQVMNMYGDLVMDTVPEK----VHFFNSFFYDKLRTKGYDGVKRWTKNVDIFN :::::...:.: ...:. :: :: ::.::. ::.: ::..::::::.::.:. XP_016 NHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFS 270 280 290 300 310 320 460 470 480 490 500 510 pF1KB8 KELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFH ..::.:::: ::: : :: :...:::.::. .: . . . .::. :.. : : .: XP_016 VDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFD 330 340 350 360 370 380 520 530 540 550 560 pF1KB8 -QGWKGYFK--MNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCH .::. . : ... .: : :::: :. .: .. ..:..:::: :: .:... :. : XP_016 TNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILH 390 400 410 420 430 440 570 pF1KB8 CKLTV :: XP_016 RKLL >>XP_006719425 (OMIM: 612157) PREDICTED: sentrin-specifi (445 aa) initn: 461 init1: 331 opt: 559 Z-score: 363.7 bits: 76.8 E(85289): 1.6e-13 Smith-Waterman score: 562; 37.0% identity (63.7% similar) in 273 aa overlap (308-572:194-444) 280 290 300 310 320 330 pF1KB8 DHVAQELFQGSDLGMAEEAERPGEKAGQHSPLREE-HVTCVQSILDEFLQTYGSLIPLST ::..: :: :: : : . : XP_006 QKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQET-----QKKGHKLTDSE 170 180 190 200 210 340 350 360 370 380 390 pF1KB8 DEVVEKLEDIFQQEFSTPSRKGLVLQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTL :: : :.. ..:... :.: ... ..::.. :. :. :: XP_006 DEFPEITEEM-EKEIKNVFRNG-----------NQDEVLSEAFRLTITRK-----DIQTL 220 230 240 250 260 400 410 420 430 440 450 pF1KB8 YGQNWLNDQVMNMYGDLVMDTVPEK----VHFFNSFFYDKLRTKGYDGVKRWTKNVDIFN :::::...:.: ...:. :: :: ::.::. ::.: ::..::::::.::.:. XP_006 NHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFS 270 280 290 300 310 320 460 470 480 490 500 510 pF1KB8 KELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFH ..::.:::: ::: : :: :...:::.::. .: . . . .::. :.. : : .: XP_006 VDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFD 330 340 350 360 370 380 520 530 540 550 560 pF1KB8 -QGWKGYFK--MNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCH .::. . : ... .: : :::: :. .: .. ..:..:::: :: .:... :. : XP_006 TNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILH 390 400 410 420 430 440 570 pF1KB8 CKLTV :: XP_006 RKLL >>XP_016874728 (OMIM: 612157) PREDICTED: sentrin-specifi (445 aa) initn: 461 init1: 331 opt: 559 Z-score: 363.7 bits: 76.8 E(85289): 1.6e-13 Smith-Waterman score: 562; 37.0% identity (63.7% similar) in 273 aa overlap (308-572:194-444) 280 290 300 310 320 330 pF1KB8 DHVAQELFQGSDLGMAEEAERPGEKAGQHSPLREE-HVTCVQSILDEFLQTYGSLIPLST ::..: :: :: : : . : XP_016 QKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQET-----QKKGHKLTDSE 170 180 190 200 210 340 350 360 370 380 390 pF1KB8 DEVVEKLEDIFQQEFSTPSRKGLVLQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTL :: : :.. ..:... :.: ... ..::.. :. :. :: XP_016 DEFPEITEEM-EKEIKNVFRNG-----------NQDEVLSEAFRLTITRK-----DIQTL 220 230 240 250 260 400 410 420 430 440 450 pF1KB8 YGQNWLNDQVMNMYGDLVMDTVPEK----VHFFNSFFYDKLRTKGYDGVKRWTKNVDIFN :::::...:.: ...:. :: :: ::.::. ::.: ::..::::::.::.:. XP_016 NHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFS 270 280 290 300 310 320 460 470 480 490 500 510 pF1KB8 KELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFH ..::.:::: ::: : :: :...:::.::. .: . . . .::. :.. : : .: XP_016 VDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFD 330 340 350 360 370 380 520 530 540 550 560 pF1KB8 -QGWKGYFK--MNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCH .::. . : ... .: : :::: :. .: .. ..:..:::: :: .:... :. : XP_016 TNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILH 390 400 410 420 430 440 570 pF1KB8 CKLTV :: XP_016 RKLL >>XP_016874726 (OMIM: 612157) PREDICTED: sentrin-specifi (631 aa) initn: 492 init1: 331 opt: 559 Z-score: 361.8 bits: 77.0 E(85289): 2.1e-13 Smith-Waterman score: 562; 37.0% identity (63.7% similar) in 273 aa overlap (308-572:380-630) 280 290 300 310 320 330 pF1KB8 DHVAQELFQGSDLGMAEEAERPGEKAGQHSPLREE-HVTCVQSILDEFLQTYGSLIPLST ::..: :: :: : : . : XP_016 QKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQET-----QKKGHKLTDSE 350 360 370 380 390 400 340 350 360 370 380 390 pF1KB8 DEVVEKLEDIFQQEFSTPSRKGLVLQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTL :: : :.. ..:... :.: ... ..::.. :. :. :: XP_016 DEFPEITEEM-EKEIKNVFRNG-----------NQDEVLSEAFRLTITRK-----DIQTL 410 420 430 440 400 410 420 430 440 450 pF1KB8 YGQNWLNDQVMNMYGDLVMDTVPEK----VHFFNSFFYDKLRTKGYDGVKRWTKNVDIFN :::::...:.: ...:. :: :: ::.::. ::.: ::..::::::.::.:. XP_016 NHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFS 450 460 470 480 490 500 460 470 480 490 500 510 pF1KB8 KELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFH ..::.:::: ::: : :: :...:::.::. .: . . . .::. :.. : : .: XP_016 VDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFD 510 520 530 540 550 560 520 530 540 550 560 pF1KB8 -QGWKGYFK--MNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCH .::. . : ... .: : :::: :. .: .. ..:..:::: :: .:... :. : XP_016 TNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILH 570 580 590 600 610 620 570 pF1KB8 CKLTV :: XP_016 RKLL 630 >>XP_016874725 (OMIM: 612157) PREDICTED: sentrin-specifi (631 aa) initn: 492 init1: 331 opt: 559 Z-score: 361.8 bits: 77.0 E(85289): 2.1e-13 Smith-Waterman score: 562; 37.0% identity (63.7% similar) in 273 aa overlap (308-572:380-630) 280 290 300 310 320 330 pF1KB8 DHVAQELFQGSDLGMAEEAERPGEKAGQHSPLREE-HVTCVQSILDEFLQTYGSLIPLST ::..: :: :: : : . : XP_016 QKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQET-----QKKGHKLTDSE 350 360 370 380 390 400 340 350 360 370 380 390 pF1KB8 DEVVEKLEDIFQQEFSTPSRKGLVLQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTL :: : :.. ..:... :.: ... ..::.. :. :. :: XP_016 DEFPEITEEM-EKEIKNVFRNG-----------NQDEVLSEAFRLTITRK-----DIQTL 410 420 430 440 400 410 420 430 440 450 pF1KB8 YGQNWLNDQVMNMYGDLVMDTVPEK----VHFFNSFFYDKLRTKGYDGVKRWTKNVDIFN :::::...:.: ...:. :: :: ::.::. ::.: ::..::::::.::.:. XP_016 NHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFS 450 460 470 480 490 500 460 470 480 490 500 510 pF1KB8 KELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFH ..::.:::: ::: : :: :...:::.::. .: . . . .::. :.. : : .: XP_016 VDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFD 510 520 530 540 550 560 520 530 540 550 560 pF1KB8 -QGWKGYFK--MNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCH .::. . : ... .: : :::: :. .: .. ..:..:::: :: .:... :. : XP_016 TNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILH 570 580 590 600 610 620 570 pF1KB8 CKLTV :: XP_016 RKLL 630 574 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:45:02 2016 done: Fri Nov 4 14:45:04 2016 Total Scan time: 13.420 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]