FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8704, 238 aa 1>>>pF1KB8704 238 - 238 aa - 238 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.7981+/-0.000388; mu= -15.5518+/- 0.024 mean_var=319.6505+/-64.139, 0's: 0 Z-trim(122.5): 10 B-trim: 0 in 0/57 Lambda= 0.071736 statistics sampled from 40674 (40688) to 40674 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.477), width: 16 Scan time: 7.900 The best scores are: opt bits E(85289) NP_002036 (OMIM: 162060) neuromodulin isoform 2 [H ( 238) 1517 169.6 4.2e-42 XP_016861617 (OMIM: 162060) PREDICTED: neuromoduli ( 274) 1441 161.8 1.1e-39 NP_001123536 (OMIM: 162060) neuromodulin isoform 1 ( 274) 1441 161.8 1.1e-39 >>NP_002036 (OMIM: 162060) neuromodulin isoform 2 [Homo (238 aa) initn: 1517 init1: 1517 opt: 1517 Z-score: 876.9 bits: 169.6 E(85289): 4.2e-42 Smith-Waterman score: 1517; 100.0% identity (100.0% similar) in 238 aa overlap (1-238:1-238) 10 20 30 40 50 60 pF1KB8 MLCCMRRTKQVEKNDDDQKIEQDGIKPEDKAHKAATKIQASFRGHITRKKLKGEKKDDVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MLCCMRRTKQVEKNDDDQKIEQDGIKPEDKAHKAATKIQASFRGHITRKKLKGEKKDDVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 AAEAEANKKDEAPVADGVEKKGEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AAEAEANKKDEAPVADGVEKKGEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAAT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EQAAPQAPASSEEKAGSAETESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EQAAPQAPASSEEKAGSAETESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAAT 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 TPAAEDAAAKATAQPPTETGESSQAEENIEAVDETKPKESARQDEGKEEEPEADQEHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TPAAEDAAAKATAQPPTETGESSQAEENIEAVDETKPKESARQDEGKEEEPEADQEHA 190 200 210 220 230 >>XP_016861617 (OMIM: 162060) PREDICTED: neuromodulin is (274 aa) initn: 1441 init1: 1441 opt: 1441 Z-score: 833.4 bits: 161.8 E(85289): 1.1e-39 Smith-Waterman score: 1441; 99.6% identity (100.0% similar) in 229 aa overlap (10-238:46-274) 10 20 30 pF1KB8 MLCCMRRTKQVEKNDDDQKIEQDGIKPEDKAHKAATKIQ .::::::::::::::::::::::::::::: XP_016 LPCLGGLRKNLQRAVRPSPYSLGFLTFWISRVEKNDDDQKIEQDGIKPEDKAHKAATKIQ 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB8 ASFRGHITRKKLKGEKKDDVQAAEAEANKKDEAPVADGVEKKGEGTTTAEAAPATGSKPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASFRGHITRKKLKGEKKDDVQAAEAEANKKDEAPVADGVEKKGEGTTTAEAAPATGSKPD 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB8 EPGKAGETPSEEKKGEGDAATEQAAPQAPASSEEKAGSAETESATKASTDNSPSSKAEDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPGKAGETPSEEKKGEGDAATEQAAPQAPASSEEKAGSAETESATKASTDNSPSSKAEDA 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB8 PAKEEPKQADVPAAVTAAAATTPAAEDAAAKATAQPPTETGESSQAEENIEAVDETKPKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAKEEPKQADVPAAVTAAAATTPAAEDAAAKATAQPPTETGESSQAEENIEAVDETKPKE 200 210 220 230 240 250 220 230 pF1KB8 SARQDEGKEEEPEADQEHA ::::::::::::::::::: XP_016 SARQDEGKEEEPEADQEHA 260 270 >>NP_001123536 (OMIM: 162060) neuromodulin isoform 1 [Ho (274 aa) initn: 1441 init1: 1441 opt: 1441 Z-score: 833.4 bits: 161.8 E(85289): 1.1e-39 Smith-Waterman score: 1441; 99.6% identity (100.0% similar) in 229 aa overlap (10-238:46-274) 10 20 30 pF1KB8 MLCCMRRTKQVEKNDDDQKIEQDGIKPEDKAHKAATKIQ .::::::::::::::::::::::::::::: NP_001 LPCLGGLRKNLQRAVRPSPYSLGFLTFWISRVEKNDDDQKIEQDGIKPEDKAHKAATKIQ 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB8 ASFRGHITRKKLKGEKKDDVQAAEAEANKKDEAPVADGVEKKGEGTTTAEAAPATGSKPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASFRGHITRKKLKGEKKDDVQAAEAEANKKDEAPVADGVEKKGEGTTTAEAAPATGSKPD 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB8 EPGKAGETPSEEKKGEGDAATEQAAPQAPASSEEKAGSAETESATKASTDNSPSSKAEDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPGKAGETPSEEKKGEGDAATEQAAPQAPASSEEKAGSAETESATKASTDNSPSSKAEDA 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB8 PAKEEPKQADVPAAVTAAAATTPAAEDAAAKATAQPPTETGESSQAEENIEAVDETKPKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAKEEPKQADVPAAVTAAAATTPAAEDAAAKATAQPPTETGESSQAEENIEAVDETKPKE 200 210 220 230 240 250 220 230 pF1KB8 SARQDEGKEEEPEADQEHA ::::::::::::::::::: NP_001 SARQDEGKEEEPEADQEHA 260 270 238 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:45:42 2016 done: Fri Nov 4 14:45:43 2016 Total Scan time: 7.900 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]