FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8705, 376 aa 1>>>pF1KB8705 376 - 376 aa - 376 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9997+/-0.000416; mu= 18.6791+/- 0.026 mean_var=73.7035+/-15.790, 0's: 0 Z-trim(111.9): 77 B-trim: 952 in 1/51 Lambda= 0.149393 statistics sampled from 20500 (20578) to 20500 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.602), E-opt: 0.2 (0.241), width: 16 Scan time: 8.040 The best scores are: opt bits E(85289) NP_598003 (OMIM: 611149) zinc transporter 7 [Homo ( 376) 2549 559.0 6.6e-159 XP_016855889 (OMIM: 611149) PREDICTED: zinc transp ( 376) 2549 559.0 6.6e-159 NP_001138356 (OMIM: 611149) zinc transporter 7 [Ho ( 376) 2549 559.0 6.6e-159 XP_011539081 (OMIM: 611149) PREDICTED: zinc transp ( 306) 2065 454.6 1.4e-127 XP_016855890 (OMIM: 611149) PREDICTED: zinc transp ( 289) 1933 426.1 5e-119 XP_016865238 (OMIM: 607819) PREDICTED: zinc transp ( 681) 642 148.2 5.5e-35 XP_006714735 (OMIM: 607819) PREDICTED: zinc transp ( 722) 642 148.2 5.7e-35 XP_005248626 (OMIM: 607819) PREDICTED: zinc transp ( 724) 642 148.2 5.7e-35 NP_075053 (OMIM: 607819) zinc transporter 5 isofor ( 765) 642 148.2 6e-35 NP_067017 (OMIM: 609521) zinc transporter 1 [Homo ( 507) 315 77.6 7.2e-14 NP_061183 (OMIM: 611146,613280) zinc transporter 1 ( 485) 285 71.1 6.2e-12 XP_016859955 (OMIM: 611148) PREDICTED: zinc transp ( 228) 235 60.0 6.2e-09 NP_001180443 (OMIM: 611148) zinc transporter 6 iso ( 438) 235 60.3 1e-08 NP_060434 (OMIM: 611148) zinc transporter 6 isofor ( 461) 235 60.3 1e-08 NP_115902 (OMIM: 608118,609617) zinc transporter 2 ( 323) 232 59.5 1.2e-08 XP_016878049 (OMIM: 602095) PREDICTED: zinc transp ( 429) 233 59.8 1.3e-08 NP_037441 (OMIM: 602095) zinc transporter 4 isofor ( 429) 233 59.8 1.3e-08 XP_011520299 (OMIM: 602095) PREDICTED: zinc transp ( 429) 233 59.8 1.3e-08 NP_001004434 (OMIM: 608118,609617) zinc transporte ( 372) 232 59.6 1.4e-08 NP_001180442 (OMIM: 611148) zinc transporter 6 iso ( 501) 231 59.5 2e-08 XP_011531405 (OMIM: 602878) PREDICTED: zinc transp ( 274) 226 58.2 2.7e-08 XP_011531404 (OMIM: 602878) PREDICTED: zinc transp ( 315) 226 58.2 3e-08 NP_001070984 (OMIM: 601416) zinc transporter SLC39 ( 469) 226 58.4 4e-08 NP_008910 (OMIM: 601416) zinc transporter SLC39A7 ( 469) 226 58.4 4e-08 NP_001305880 (OMIM: 602878) zinc transporter 3 iso ( 375) 222 57.4 6.2e-08 NP_001305879 (OMIM: 602878) zinc transporter 3 iso ( 375) 222 57.4 6.2e-08 NP_001305878 (OMIM: 602878) zinc transporter 3 iso ( 383) 222 57.4 6.3e-08 NP_003450 (OMIM: 602878) zinc transporter 3 a [Hom ( 388) 222 57.4 6.4e-08 XP_016857173 (OMIM: 611146,613280) PREDICTED: zinc ( 326) 196 51.8 2.7e-06 XP_006711500 (OMIM: 611146,613280) PREDICTED: zinc ( 422) 196 51.9 3.3e-06 NP_001166286 (OMIM: 125853,611145) zinc transporte ( 320) 188 50.0 8.9e-06 NP_001166284 (OMIM: 125853,611145) zinc transporte ( 320) 188 50.0 8.9e-06 NP_001166282 (OMIM: 125853,611145) zinc transporte ( 320) 188 50.0 8.9e-06 NP_001166285 (OMIM: 125853,611145) zinc transporte ( 320) 188 50.0 8.9e-06 NP_776250 (OMIM: 125853,611145) zinc transporter 8 ( 369) 188 50.1 9.9e-06 NP_001317406 (OMIM: 611148) zinc transporter 6 iso ( 264) 185 49.3 1.2e-05 XP_006712111 (OMIM: 611148) PREDICTED: zinc transp ( 264) 185 49.3 1.2e-05 NP_001317407 (OMIM: 611148) zinc transporter 6 iso ( 264) 185 49.3 1.2e-05 XP_016859951 (OMIM: 611148) PREDICTED: zinc transp ( 387) 186 49.7 1.4e-05 NP_001317405 (OMIM: 611148) zinc transporter 6 iso ( 387) 186 49.7 1.4e-05 XP_011531264 (OMIM: 611148) PREDICTED: zinc transp ( 387) 186 49.7 1.4e-05 NP_001180444 (OMIM: 611148) zinc transporter 6 iso ( 432) 178 48.0 4.9e-05 NP_001317408 (OMIM: 611148) zinc transporter 6 iso ( 412) 169 46.0 0.00018 XP_016859954 (OMIM: 611148) PREDICTED: zinc transp ( 267) 156 43.1 0.00092 XP_016859953 (OMIM: 611148) PREDICTED: zinc transp ( 268) 156 43.1 0.00093 XP_016859952 (OMIM: 611148) PREDICTED: zinc transp ( 340) 156 43.2 0.0011 XP_011531265 (OMIM: 611148) PREDICTED: zinc transp ( 362) 156 43.2 0.0012 XP_011531261 (OMIM: 611148) PREDICTED: zinc transp ( 478) 156 43.3 0.0014 NP_001095886 (OMIM: 228960,612358) kininogen-1 iso ( 644) 156 43.4 0.0018 >>NP_598003 (OMIM: 611149) zinc transporter 7 [Homo sapi (376 aa) initn: 2549 init1: 2549 opt: 2549 Z-score: 2973.9 bits: 559.0 E(85289): 6.6e-159 Smith-Waterman score: 2549; 100.0% identity (100.0% similar) in 376 aa overlap (1-376:1-376) 10 20 30 40 50 60 pF1KB8 MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 CLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 CLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFKHGGHGHSHGSGHGHSHSLFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 FIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFKHGGHGHSHGSGHGHSHSLFN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSHDGPSLKETTGPSRQILQGVFLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 GALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSHDGPSLKETTGPSRQILQGVFLH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILMQRTPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 ILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILMQRTPPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLIVAPDADARWILSQTHNIFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 LENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLIVAPDADARWILSQTHNIFT 310 320 330 340 350 360 370 pF1KB8 QAGVRQLYVQIDFAAM :::::::::::::::: NP_598 QAGVRQLYVQIDFAAM 370 >>XP_016855889 (OMIM: 611149) PREDICTED: zinc transporte (376 aa) initn: 2549 init1: 2549 opt: 2549 Z-score: 2973.9 bits: 559.0 E(85289): 6.6e-159 Smith-Waterman score: 2549; 100.0% identity (100.0% similar) in 376 aa overlap (1-376:1-376) 10 20 30 40 50 60 pF1KB8 MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 CLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFKHGGHGHSHGSGHGHSHSLFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFKHGGHGHSHGSGHGHSHSLFN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSHDGPSLKETTGPSRQILQGVFLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSHDGPSLKETTGPSRQILQGVFLH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILMQRTPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILMQRTPPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLIVAPDADARWILSQTHNIFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLIVAPDADARWILSQTHNIFT 310 320 330 340 350 360 370 pF1KB8 QAGVRQLYVQIDFAAM :::::::::::::::: XP_016 QAGVRQLYVQIDFAAM 370 >>NP_001138356 (OMIM: 611149) zinc transporter 7 [Homo s (376 aa) initn: 2549 init1: 2549 opt: 2549 Z-score: 2973.9 bits: 559.0 E(85289): 6.6e-159 Smith-Waterman score: 2549; 100.0% identity (100.0% similar) in 376 aa overlap (1-376:1-376) 10 20 30 40 50 60 pF1KB8 MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 CLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFKHGGHGHSHGSGHGHSHSLFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFKHGGHGHSHGSGHGHSHSLFN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSHDGPSLKETTGPSRQILQGVFLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSHDGPSLKETTGPSRQILQGVFLH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILMQRTPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILMQRTPPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLIVAPDADARWILSQTHNIFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLIVAPDADARWILSQTHNIFT 310 320 330 340 350 360 370 pF1KB8 QAGVRQLYVQIDFAAM :::::::::::::::: NP_001 QAGVRQLYVQIDFAAM 370 >>XP_011539081 (OMIM: 611149) PREDICTED: zinc transporte (306 aa) initn: 2065 init1: 2065 opt: 2065 Z-score: 2411.3 bits: 454.6 E(85289): 1.4e-127 Smith-Waterman score: 2065; 100.0% identity (100.0% similar) in 306 aa overlap (71-376:1-306) 50 60 70 80 90 100 pF1KB8 FLCLNLSFAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGY :::::::::::::::::::::::::::::: XP_011 MFFDSTAILAGLAASVISKWRDNDAFSYGY 10 20 30 110 120 130 140 150 160 pF1KB8 VRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFK 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB8 HGGHGHSHGSGHGHSHSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSHDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HGGHGHSHGSGHGHSHSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSHDG 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB8 PSLKETTGPSRQILQGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSLKETTGPSRQILQGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVV 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB8 SVIPLLRESVGILMQRTPPLLENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVIPLLRESVGILMQRTPPLLENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKL 220 230 240 250 260 270 350 360 370 pF1KB8 IVAPDADARWILSQTHNIFTQAGVRQLYVQIDFAAM :::::::::::::::::::::::::::::::::::: XP_011 IVAPDADARWILSQTHNIFTQAGVRQLYVQIDFAAM 280 290 300 >>XP_016855890 (OMIM: 611149) PREDICTED: zinc transporte (289 aa) initn: 2249 init1: 1933 opt: 1933 Z-score: 2257.9 bits: 426.1 E(85289): 5e-119 Smith-Waterman score: 1933; 99.6% identity (100.0% similar) in 285 aa overlap (1-285:1-285) 10 20 30 40 50 60 pF1KB8 MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 CLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFKHGGHGHSHGSGHGHSHSLFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFKHGGHGHSHGSGHGHSHSLFN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSHDGPSLKETTGPSRQILQGVFLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSHDGPSLKETTGPSRQILQGVFLH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILMQRTPPL ::::::::::::::::::::::::::::::::::::::::::::. XP_016 ILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPFPQKF 250 260 270 280 310 320 330 340 350 360 pF1KB8 LENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLIVAPDADARWILSQTHNIFT >>XP_016865238 (OMIM: 607819) PREDICTED: zinc transporte (681 aa) initn: 970 init1: 510 opt: 642 Z-score: 749.1 bits: 148.2 E(85289): 5.5e-35 Smith-Waterman score: 890; 46.2% identity (71.3% similar) in 303 aa overlap (26-324:366-641) 10 20 30 40 50 pF1KB8 MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLY ...:: .. ::..:.:::::: :.::::.: XP_016 YSPEGTPLYNFMGDAFQHSSQSIPRFIKESLKQILEESDSRQIFYFLCLNLLFTFVELFY 340 350 360 370 380 390 60 70 80 90 100 110 pF1KB8 GIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFL :. .: ::::::.:::.:: .:.. :: :...:.:. . ::::: : :.:.::.::::: XP_016 GVLTNSLGLISDGFHMLFDCSALVMGLFAALMSRWKATRIFSYGYGRIEILSGFINGLFL 400 410 420 430 440 450 120 130 140 150 160 170 pF1KB8 IFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFKHGGHGHSHGSGHGHS : :::.: :.: : . ::.. . : ::. :..:::::: .:.:. :.:.::...: XP_016 IVIAFFVFMESVARLIDPPELDTHMLTPVSVGGLIVNLIGICAFSHA-HSHAHGASQGSC 460 470 480 490 500 510 180 190 200 210 220 230 pF1KB8 HSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHA-HGHGHFHSHDGPSLKETTGPSRQIL :: :: ::: : : :. ::::: :. : ... . . XP_016 HS------------SDHSHSH-------HMHGHSDHGHGHSHGSAGGGMNAN-------M 520 530 540 240 250 260 270 280 290 pF1KB8 QGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILM .:::::.:::::::::::.:......:: .::::.::..::::: .::.::.... .:. XP_016 RGVFLHVLADTLGSIGVIVSTVLIEQFGWFIADPLCSLFIAILIFLSVVPLIKDACQVLL 550 560 570 580 590 600 300 310 320 330 340 350 pF1KB8 QRTPPLLENSLPQCYQRVQQL---QGVYSLQEQHFWTLCSDVYVGTLKLIVAPDADARWI : :: :. : ..: . :: .: : XP_016 LRLPPEYEKELHIALEKVTGILKDAGVNNLTIQVEKEAYFQHMSGLSTGFHDVLAMTKQM 610 620 630 640 650 660 360 370 pF1KB8 LSQTHNIFTQAGVRQLYVQIDFAAM XP_016 ESMKYCKDGTYIM 670 680 >>XP_006714735 (OMIM: 607819) PREDICTED: zinc transporte (722 aa) initn: 970 init1: 510 opt: 642 Z-score: 748.8 bits: 148.2 E(85289): 5.7e-35 Smith-Waterman score: 890; 46.2% identity (71.3% similar) in 303 aa overlap (26-324:407-682) 10 20 30 40 50 pF1KB8 MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLY ...:: .. ::..:.:::::: :.::::.: XP_006 YSPEGTPLYNFMGDAFQHSSQSIPRFIKESLKQILEESDSRQIFYFLCLNLLFTFVELFY 380 390 400 410 420 430 60 70 80 90 100 110 pF1KB8 GIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFL :. .: ::::::.:::.:: .:.. :: :...:.:. . ::::: : :.:.::.::::: XP_006 GVLTNSLGLISDGFHMLFDCSALVMGLFAALMSRWKATRIFSYGYGRIEILSGFINGLFL 440 450 460 470 480 490 120 130 140 150 160 170 pF1KB8 IFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFKHGGHGHSHGSGHGHS : :::.: :.: : . ::.. . : ::. :..:::::: .:.:. :.:.::...: XP_006 IVIAFFVFMESVARLIDPPELDTHMLTPVSVGGLIVNLIGICAFSHA-HSHAHGASQGSC 500 510 520 530 540 550 180 190 200 210 220 230 pF1KB8 HSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHA-HGHGHFHSHDGPSLKETTGPSRQIL :: :: ::: : : :. ::::: :. : ... . . XP_006 HS------------SDHSHSH-------HMHGHSDHGHGHSHGSAGGGMNAN-------M 560 570 580 240 250 260 270 280 290 pF1KB8 QGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILM .:::::.:::::::::::.:......:: .::::.::..::::: .::.::.... .:. XP_006 RGVFLHVLADTLGSIGVIVSTVLIEQFGWFIADPLCSLFIAILIFLSVVPLIKDACQVLL 590 600 610 620 630 640 300 310 320 330 340 350 pF1KB8 QRTPPLLENSLPQCYQRVQQL---QGVYSLQEQHFWTLCSDVYVGTLKLIVAPDADARWI : :: :. : ..: . :: .: : XP_006 LRLPPEYEKELHIALEKVTGILKDAGVNNLTIQVEKEAYFQHMSGLSTGFHDVLAMTKQM 650 660 670 680 690 700 360 370 pF1KB8 LSQTHNIFTQAGVRQLYVQIDFAAM XP_006 ESMKYCKDGTYIM 710 720 >>XP_005248626 (OMIM: 607819) PREDICTED: zinc transporte (724 aa) initn: 1084 init1: 510 opt: 642 Z-score: 748.8 bits: 148.2 E(85289): 5.7e-35 Smith-Waterman score: 1019; 44.0% identity (73.0% similar) in 348 aa overlap (26-372:366-686) 10 20 30 40 50 pF1KB8 MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLY ...:: .. ::..:.:::::: :.::::.: XP_005 YSPEGTPLYNFMGDAFQHSSQSIPRFIKESLKQILEESDSRQIFYFLCLNLLFTFVELFY 340 350 360 370 380 390 60 70 80 90 100 110 pF1KB8 GIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFL :. .: ::::::.:::.:: .:.. :: :...:.:. . ::::: : :.:.::.::::: XP_005 GVLTNSLGLISDGFHMLFDCSALVMGLFAALMSRWKATRIFSYGYGRIEILSGFINGLFL 400 410 420 430 440 450 120 130 140 150 160 170 pF1KB8 IFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFKHGGHGHSHGSGHGHS : :::.: :.: : . ::.. . : ::. :..:::::: .:.:. :.:.::...: XP_005 IVIAFFVFMESVARLIDPPELDTHMLTPVSVGGLIVNLIGICAFSHA-HSHAHGASQGSC 460 470 480 490 500 510 180 190 200 210 220 230 pF1KB8 HSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHA-HGHGHFHSHDGPSLKETTGPSRQIL :: :: ::: : : :. ::::: :. : ... . . XP_005 HS------------SDHSHSH-------HMHGHSDHGHGHSHGSAGGGMNAN-------M 520 530 540 240 250 260 270 280 290 pF1KB8 QGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILM .:::::.:::::::::::.:......:: .::::.::..::::: .::.::.... .:. XP_005 RGVFLHVLADTLGSIGVIVSTVLIEQFGWFIADPLCSLFIAILIFLSVVPLIKDACQVLL 550 560 570 580 590 600 300 310 320 330 340 350 pF1KB8 QRTPPLLENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLIVAPDADARWILSQ : :: :. : ...:...:. : .. ::: ... .::... :. :. . :..: XP_005 LRLPPEYEKELHIALEKIQKIEGLISYRDPHFWRHSASIVAGTIHIQVTSDVLEQRIVQQ 610 620 630 640 650 660 360 370 pF1KB8 THNIFTQAGVRQLYVQIDFAAM . .:. .::: .: .:.. XP_005 VTGILKDAGVNNLTIQVEKEAYFQHMSGLSTGFHDVLAMTKQMESMKYCKDGTYIM 670 680 690 700 710 720 >>NP_075053 (OMIM: 607819) zinc transporter 5 isoform 1 (765 aa) initn: 1103 init1: 510 opt: 642 Z-score: 748.5 bits: 148.2 E(85289): 6e-35 Smith-Waterman score: 1019; 44.0% identity (73.0% similar) in 348 aa overlap (26-372:407-727) 10 20 30 40 50 pF1KB8 MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLY ...:: .. ::..:.:::::: :.::::.: NP_075 YSPEGTPLYNFMGDAFQHSSQSIPRFIKESLKQILEESDSRQIFYFLCLNLLFTFVELFY 380 390 400 410 420 430 60 70 80 90 100 110 pF1KB8 GIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFL :. .: ::::::.:::.:: .:.. :: :...:.:. . ::::: : :.:.::.::::: NP_075 GVLTNSLGLISDGFHMLFDCSALVMGLFAALMSRWKATRIFSYGYGRIEILSGFINGLFL 440 450 460 470 480 490 120 130 140 150 160 170 pF1KB8 IFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFKHGGHGHSHGSGHGHS : :::.: :.: : . ::.. . : ::. :..:::::: .:.:. :.:.::...: NP_075 IVIAFFVFMESVARLIDPPELDTHMLTPVSVGGLIVNLIGICAFSHA-HSHAHGASQGSC 500 510 520 530 540 550 180 190 200 210 220 230 pF1KB8 HSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHA-HGHGHFHSHDGPSLKETTGPSRQIL :: :: ::: : : :. ::::: :. : ... . . NP_075 HS------------SDHSHSH-------HMHGHSDHGHGHSHGSAGGGMNAN-------M 560 570 580 240 250 260 270 280 290 pF1KB8 QGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILM .:::::.:::::::::::.:......:: .::::.::..::::: .::.::.... .:. NP_075 RGVFLHVLADTLGSIGVIVSTVLIEQFGWFIADPLCSLFIAILIFLSVVPLIKDACQVLL 590 600 610 620 630 640 300 310 320 330 340 350 pF1KB8 QRTPPLLENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLIVAPDADARWILSQ : :: :. : ...:...:. : .. ::: ... .::... :. :. . :..: NP_075 LRLPPEYEKELHIALEKIQKIEGLISYRDPHFWRHSASIVAGTIHIQVTSDVLEQRIVQQ 650 660 670 680 690 700 360 370 pF1KB8 THNIFTQAGVRQLYVQIDFAAM . .:. .::: .: .:.. NP_075 VTGILKDAGVNNLTIQVEKEAYFQHMSGLSTGFHDVLAMTKQMESMKYCKDGTYIM 710 720 730 740 750 760 >>NP_067017 (OMIM: 609521) zinc transporter 1 [Homo sapi (507 aa) initn: 356 init1: 160 opt: 315 Z-score: 370.0 bits: 77.6 E(85289): 7.2e-14 Smith-Waterman score: 366; 26.8% identity (56.2% similar) in 377 aa overlap (36-329:6-377) 10 20 30 40 50 60 pF1KB8 IKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLC-LNLSFAFV--ELLYGIWSNCL :: .:: : :.: :. :.. . .. : NP_067 MGCWGRNRGRLLCMLALTFMFMVLEVVVSRVTSSL 10 20 30 70 80 90 100 110 120 pF1KB8 GLISDSFHMFFDSTAILAGLAASVISKWRD-NDAFSYGYVRAEVLAGFVNGLFLIFTAFF ...::::::. : :....:.: ... .. ..:..::::....::..:: : NP_067 AMLSDSFHMLSDVLALVVALVAERFARRTHATQKNTFGWIRAEVMGALVNAIFLTGLCFA 40 50 60 70 80 90 130 140 150 160 170 pF1KB8 IFSEGVERALAPPDVHHERLLL-VSILGFVVNLIGIFVFKH-------GGHGHSHGSGHG :. :..:: . : .... ..: :.. :..::..:. .:.: .::::::: ::: NP_067 ILLEAIERFIEPHEMQQPLVVLGVGVAGLLVNVLGLCLFHHHSGFSQDSGHGHSHG-GHG 100 110 120 130 140 150 180 190 200 210 pF1KB8 HSHSLFNGA-----------LDQAHGH------------VDHCHSHEVKHGAAHSHDHAH :.:.: .: .. : :. .. .:. .: : .. NP_067 HGHGLPKGPRVKSTRPGSSDINVAPGEQGPDQEETNTLVANTSNSNGLKLDPADPENPRS 160 170 180 190 200 210 220 230 240 250 pF1KB8 G-------HGHF-HSHDGPSLKETTGPSRQILQGVFLHILADTLGSIGVIASAIMM---- : .:.. . : :.: . .. ..:::::.:.:.:::. :...:... NP_067 GDTVEVQVNGNLVREPDHMELEEDRA-GQLNMRGVFLHVLGDALGSVIVVVNALVFYFSW 220 230 240 250 260 270 260 270 280 pF1KB8 ------------------QNFGLMIA-----------------DP-ICSILIAILIVVSV . : .: :: .: ... ::. .. NP_067 KGCSEGDFCVNPCFPDPCKAFVEIINSTHASVYEAGPCWVLYLDPTLCVVMVCILLYTTY 280 290 300 310 320 330 290 300 310 320 330 340 pF1KB8 IPLLRESVGILMQRTPPLLENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLIV :::.::. ::.: .: .. . . .......:: ..: : : : NP_067 -PLLKESALILLQTVPKQID--IRNLIKELRNVEGVEEVHELHVWQLAGSRIIATAHIKC 340 350 360 370 380 390 350 360 370 pF1KB8 APDADARWILSQTHNIFTQAGVRQLYVQIDFAAM NP_067 EDPTSYMEVAKTIKDVFHNHGIHATTIQPEFASVGSKSSVVPCELACRTQCALKQCCGTL 400 410 420 430 440 450 376 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:46:20 2016 done: Fri Nov 4 14:46:21 2016 Total Scan time: 8.040 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]