FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8706, 490 aa 1>>>pF1KB8706 490 - 490 aa - 490 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8256+/-0.000452; mu= 15.1314+/- 0.028 mean_var=67.6115+/-13.844, 0's: 0 Z-trim(109.2): 71 B-trim: 0 in 0/49 Lambda= 0.155978 statistics sampled from 17317 (17387) to 17317 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.538), E-opt: 0.2 (0.204), width: 16 Scan time: 9.350 The best scores are: opt bits E(85289) NP_071903 (OMIM: 135750,174500,186200,188740,20050 ( 490) 3114 710.2 3.3e-204 XP_005249612 (OMIM: 135750,174500,186200,188740,20 ( 436) 2598 594.1 2.6e-169 XP_016868000 (OMIM: 135750,174500,186200,188740,20 ( 397) 2431 556.5 5e-158 XP_016868003 (OMIM: 135750,174500,186200,188740,20 ( 367) 2323 532.2 9.6e-151 XP_016868007 (OMIM: 135750,174500,186200,188740,20 ( 338) 2138 490.5 3e-138 XP_016868006 (OMIM: 135750,174500,186200,188740,20 ( 338) 2138 490.5 3e-138 XP_016868005 (OMIM: 135750,174500,186200,188740,20 ( 343) 1915 440.4 3.9e-123 NP_060583 (OMIM: 610007) protein LMBR1L isoform 1 ( 489) 1902 437.5 4.1e-122 XP_011536866 (OMIM: 610007) PREDICTED: protein LMB ( 450) 1786 411.4 2.8e-114 XP_016875115 (OMIM: 610007) PREDICTED: protein LMB ( 484) 1786 411.4 2.9e-114 XP_011536865 (OMIM: 610007) PREDICTED: protein LMB ( 484) 1786 411.4 2.9e-114 NP_001287679 (OMIM: 610007) protein LMBR1L isoform ( 484) 1786 411.4 2.9e-114 XP_005249615 (OMIM: 135750,174500,186200,188740,20 ( 304) 1779 409.7 5.8e-114 XP_016875117 (OMIM: 610007) PREDICTED: protein LMB ( 435) 1623 374.7 2.9e-103 XP_016868004 (OMIM: 135750,174500,186200,188740,20 ( 345) 1617 373.3 6.1e-103 XP_016867998 (OMIM: 135750,174500,186200,188740,20 ( 477) 1617 373.3 8.2e-103 XP_016867996 (OMIM: 135750,174500,186200,188740,20 ( 531) 1617 373.4 9e-103 XP_016868002 (OMIM: 135750,174500,186200,188740,20 ( 379) 1489 344.5 3.1e-94 XP_016868001 (OMIM: 135750,174500,186200,188740,20 ( 379) 1489 344.5 3.1e-94 XP_016867999 (OMIM: 135750,174500,186200,188740,20 ( 438) 1489 344.5 3.5e-94 XP_016867997 (OMIM: 135750,174500,186200,188740,20 ( 517) 1489 344.6 4.1e-94 XP_011536867 (OMIM: 610007) PREDICTED: protein LMB ( 362) 1415 327.9 3.1e-89 NP_001287680 (OMIM: 610007) protein LMBR1L isoform ( 469) 1300 302.0 2.4e-81 XP_016875118 (OMIM: 610007) PREDICTED: protein LMB ( 430) 1184 275.9 1.6e-73 XP_016875116 (OMIM: 610007) PREDICTED: protein LMB ( 464) 1184 275.9 1.7e-73 XP_011536868 (OMIM: 610007) PREDICTED: protein LMB ( 281) 892 210.1 6.5e-54 XP_016875119 (OMIM: 610007) PREDICTED: protein LMB ( 281) 892 210.1 6.5e-54 XP_016875120 (OMIM: 610007) PREDICTED: protein LMB ( 261) 558 135.0 2.6e-31 >>NP_071903 (OMIM: 135750,174500,186200,188740,200500,60 (490 aa) initn: 3114 init1: 3114 opt: 3114 Z-score: 3787.2 bits: 710.2 E(85289): 3.3e-204 Smith-Waterman score: 3114; 99.6% identity (100.0% similar) in 490 aa overlap (1-490:1-490) 10 20 30 40 50 60 pF1KB8 MEGQDEVSAREQHFHSQVRESTICFLLFAILYVVSYFIITRYKRKSDEQEDEDAIVNRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 MEGQDEVSAREQHFHSQVRESTICFLLFAILYVVSYFIITRYKRKSDEQEDEDAIVNRIS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LFLSTFTLAVSAGAVLLLPFSIISNEILLSFPQNYYIQWLNGSLIHGLWNLASLFSNLCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 LFLSTFTLAVSAGAVLLLPFSIISNEILLSFPQNYYIQWLNGSLIHGLWNLASLFSNLCL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FVLMPFAFFFLESEGFAGLKKGIRARILETLVMLLLLALLILGIVWVASALIDNDAASME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 FVLMPFAFFFLESEGFAGLKKGIRARILETLVMLLLLALLILGIVWVASALIDNDAASME 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SLYDLWEFYLPYLYSCISLMGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 SLYDLWEFYLPYLYSCISLMGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYII 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TLEEEALQRRLNGLSSSVEYNIMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 TLEEEALQRRLNGLSSSVEYNIMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LLIETSISALLVACNILCLLVDETAMPKGTRGPGIGNASLSTFGFVGAALEIILIFYLMV ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 LLIETSISVLLVACNILCLLVDETAMPKGTRGPGIGNASLSTFGFVGAALEIILIFYLMV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SSVVGFYSLRFFGNFTPKKDDTTMTKIIGNCVSILVLSSALPVMSRTLGITRFDLLGDFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 SSVVGFYSLRFFGNFTPKKDDTTMTKIIGNCVSILVLSSALPVMSRTLGITRFDLLGDFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 RFNWLGNFYIVLSYNLLFAIVTTLCLVRKFASAVREELFKALGLHKLHLPNTSRDSETAK ::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::: NP_071 RFNWLGNFYIVLSYNLLFAIVTTLCLVRKFTSAVREELFKALGLHKLHLPNTSRDSETAK 430 440 450 460 470 480 490 pF1KB8 PSVNGHQKAL :::::::::: NP_071 PSVNGHQKAL 490 >>XP_005249612 (OMIM: 135750,174500,186200,188740,200500 (436 aa) initn: 2621 init1: 2598 opt: 2598 Z-score: 3160.5 bits: 594.1 E(85289): 2.6e-169 Smith-Waterman score: 2650; 88.8% identity (89.0% similar) in 490 aa overlap (1-490:1-436) 10 20 30 40 50 60 pF1KB8 MEGQDEVSAREQHFHSQVRESTICFLLFAILYVVSYFIITRYKRKSDEQEDEDAIVNRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEGQDEVSAREQHFHSQVRESTICFLLFAILYVVSYFIITRYKRKSDEQEDEDAIVNRIS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LFLSTFTLAVSAGAVLLLPFSIISNEILLSFPQNYYIQWLNGSLIHGLWNLASLFSNLCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LFLSTFTLAVSAGAVLLLPFSIISNEILLSFPQNYYIQWLNGSLIHGLWNLASLFSNLCL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FVLMPFAFFFLESEGFAGLKKGIRARILETLVMLLLLALLILGIVWVASALIDNDAASME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FVLMPFAFFFLESEGFAGLKKGIRARILETLVMLLLLALLILGIVWVASALIDNDAASME 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SLYDLWEFYLPYLYSCISLMGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLYDLWEFYLPYLYSCISLMGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYII 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TLEEEALQRRLNGLSSSVEYNIMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLEEEALQRRLNGLSSSVEYNIMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LLIETSISALLVACNILCLLVDETAMPKGTRGPGIGNASLSTFGFVGAALEIILIFYLMV ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLIETSISVLLVACNILCLLVDETAMPKGTRGPGIGNASLSTFGFVGAALEIILIFYLMV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SSVVGFYSLRFFGNFTPKKDDTTMTKIIGNCVSILVLSSALPVMSRTLGITRFDLLGDFG ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSVVGFYSLRFFGNFTPKKDDTTMTKIIGNCVSILVLSSALPVMSRTLG----------- 370 380 390 400 430 440 450 460 470 480 pF1KB8 RFNWLGNFYIVLSYNLLFAIVTTLCLVRKFASAVREELFKALGLHKLHLPNTSRDSETAK ::::::::::::::::: XP_005 -------------------------------------------LHKLHLPNTSRDSETAK 410 420 490 pF1KB8 PSVNGHQKAL :::::::::: XP_005 PSVNGHQKAL 430 >>XP_016868000 (OMIM: 135750,174500,186200,188740,200500 (397 aa) initn: 2431 init1: 2431 opt: 2431 Z-score: 2958.1 bits: 556.5 E(85289): 5e-158 Smith-Waterman score: 2431; 99.5% identity (100.0% similar) in 383 aa overlap (108-490:15-397) 80 90 100 110 120 130 pF1KB8 LPFSIISNEILLSFPQNYYIQWLNGSLIHGLWNLASLFSNLCLFVLMPFAFFFLESEGFA :::::::::::::::::::::::::::::: XP_016 MNKKMKMPSSTGFRLWNLASLFSNLCLFVLMPFAFFFLESEGFA 10 20 30 40 140 150 160 170 180 190 pF1KB8 GLKKGIRARILETLVMLLLLALLILGIVWVASALIDNDAASMESLYDLWEFYLPYLYSCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLKKGIRARILETLVMLLLLALLILGIVWVASALIDNDAASMESLYDLWEFYLPYLYSCI 50 60 70 80 90 100 200 210 220 230 240 250 pF1KB8 SLMGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYIITLEEEALQRRLNGLSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLMGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYIITLEEEALQRRLNGLSSS 110 120 130 140 150 160 260 270 280 290 300 310 pF1KB8 VEYNIMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVLLLIETSISALLVACNIL :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: XP_016 VEYNIMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVLLLIETSISVLLVACNIL 170 180 190 200 210 220 320 330 340 350 360 370 pF1KB8 CLLVDETAMPKGTRGPGIGNASLSTFGFVGAALEIILIFYLMVSSVVGFYSLRFFGNFTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLLVDETAMPKGTRGPGIGNASLSTFGFVGAALEIILIFYLMVSSVVGFYSLRFFGNFTP 230 240 250 260 270 280 380 390 400 410 420 430 pF1KB8 KKDDTTMTKIIGNCVSILVLSSALPVMSRTLGITRFDLLGDFGRFNWLGNFYIVLSYNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKDDTTMTKIIGNCVSILVLSSALPVMSRTLGITRFDLLGDFGRFNWLGNFYIVLSYNLL 290 300 310 320 330 340 440 450 460 470 480 490 pF1KB8 FAIVTTLCLVRKFASAVREELFKALGLHKLHLPNTSRDSETAKPSVNGHQKAL :::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_016 FAIVTTLCLVRKFTSAVREELFKALGLHKLHLPNTSRDSETAKPSVNGHQKAL 350 360 370 380 390 >>XP_016868003 (OMIM: 135750,174500,186200,188740,200500 (367 aa) initn: 2323 init1: 2323 opt: 2323 Z-score: 2827.3 bits: 532.2 E(85289): 9.6e-151 Smith-Waterman score: 2323; 99.5% identity (100.0% similar) in 367 aa overlap (124-490:1-367) 100 110 120 130 140 150 pF1KB8 NYYIQWLNGSLIHGLWNLASLFSNLCLFVLMPFAFFFLESEGFAGLKKGIRARILETLVM :::::::::::::::::::::::::::::: XP_016 MPFAFFFLESEGFAGLKKGIRARILETLVM 10 20 30 160 170 180 190 200 210 pF1KB8 LLLLALLILGIVWVASALIDNDAASMESLYDLWEFYLPYLYSCISLMGCLLLLLCTPVGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLLLALLILGIVWVASALIDNDAASMESLYDLWEFYLPYLYSCISLMGCLLLLLCTPVGL 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB8 SRMFTVMGQLLVKPTILEDLDEQIYIITLEEEALQRRLNGLSSSVEYNIMELEQELENVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRMFTVMGQLLVKPTILEDLDEQIYIITLEEEALQRRLNGLSSSVEYNIMELEQELENVK 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB8 TLKTKLERRKKASAWERNLVYPAVMVLLLIETSISALLVACNILCLLVDETAMPKGTRGP :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: XP_016 TLKTKLERRKKASAWERNLVYPAVMVLLLIETSISVLLVACNILCLLVDETAMPKGTRGP 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB8 GIGNASLSTFGFVGAALEIILIFYLMVSSVVGFYSLRFFGNFTPKKDDTTMTKIIGNCVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GIGNASLSTFGFVGAALEIILIFYLMVSSVVGFYSLRFFGNFTPKKDDTTMTKIIGNCVS 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB8 ILVLSSALPVMSRTLGITRFDLLGDFGRFNWLGNFYIVLSYNLLFAIVTTLCLVRKFASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:: XP_016 ILVLSSALPVMSRTLGITRFDLLGDFGRFNWLGNFYIVLSYNLLFAIVTTLCLVRKFTSA 280 290 300 310 320 330 460 470 480 490 pF1KB8 VREELFKALGLHKLHLPNTSRDSETAKPSVNGHQKAL ::::::::::::::::::::::::::::::::::::: XP_016 VREELFKALGLHKLHLPNTSRDSETAKPSVNGHQKAL 340 350 360 >>XP_016868007 (OMIM: 135750,174500,186200,188740,200500 (338 aa) initn: 2138 init1: 2138 opt: 2138 Z-score: 2602.9 bits: 490.5 E(85289): 3e-138 Smith-Waterman score: 2138; 99.4% identity (100.0% similar) in 338 aa overlap (153-490:1-338) 130 140 150 160 170 180 pF1KB8 LMPFAFFFLESEGFAGLKKGIRARILETLVMLLLLALLILGIVWVASALIDNDAASMESL :::::::::::::::::::::::::::::: XP_016 MLLLLALLILGIVWVASALIDNDAASMESL 10 20 30 190 200 210 220 230 240 pF1KB8 YDLWEFYLPYLYSCISLMGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYIITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDLWEFYLPYLYSCISLMGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYIITL 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB8 EEEALQRRLNGLSSSVEYNIMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEALQRRLNGLSSSVEYNIMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVLLL 100 110 120 130 140 150 310 320 330 340 350 360 pF1KB8 IETSISALLVACNILCLLVDETAMPKGTRGPGIGNASLSTFGFVGAALEIILIFYLMVSS ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IETSISVLLVACNILCLLVDETAMPKGTRGPGIGNASLSTFGFVGAALEIILIFYLMVSS 160 170 180 190 200 210 370 380 390 400 410 420 pF1KB8 VVGFYSLRFFGNFTPKKDDTTMTKIIGNCVSILVLSSALPVMSRTLGITRFDLLGDFGRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVGFYSLRFFGNFTPKKDDTTMTKIIGNCVSILVLSSALPVMSRTLGITRFDLLGDFGRF 220 230 240 250 260 270 430 440 450 460 470 480 pF1KB8 NWLGNFYIVLSYNLLFAIVTTLCLVRKFASAVREELFKALGLHKLHLPNTSRDSETAKPS ::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::: XP_016 NWLGNFYIVLSYNLLFAIVTTLCLVRKFTSAVREELFKALGLHKLHLPNTSRDSETAKPS 280 290 300 310 320 330 490 pF1KB8 VNGHQKAL :::::::: XP_016 VNGHQKAL >>XP_016868006 (OMIM: 135750,174500,186200,188740,200500 (338 aa) initn: 2138 init1: 2138 opt: 2138 Z-score: 2602.9 bits: 490.5 E(85289): 3e-138 Smith-Waterman score: 2138; 99.4% identity (100.0% similar) in 338 aa overlap (153-490:1-338) 130 140 150 160 170 180 pF1KB8 LMPFAFFFLESEGFAGLKKGIRARILETLVMLLLLALLILGIVWVASALIDNDAASMESL :::::::::::::::::::::::::::::: XP_016 MLLLLALLILGIVWVASALIDNDAASMESL 10 20 30 190 200 210 220 230 240 pF1KB8 YDLWEFYLPYLYSCISLMGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYIITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDLWEFYLPYLYSCISLMGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYIITL 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB8 EEEALQRRLNGLSSSVEYNIMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEALQRRLNGLSSSVEYNIMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVLLL 100 110 120 130 140 150 310 320 330 340 350 360 pF1KB8 IETSISALLVACNILCLLVDETAMPKGTRGPGIGNASLSTFGFVGAALEIILIFYLMVSS ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IETSISVLLVACNILCLLVDETAMPKGTRGPGIGNASLSTFGFVGAALEIILIFYLMVSS 160 170 180 190 200 210 370 380 390 400 410 420 pF1KB8 VVGFYSLRFFGNFTPKKDDTTMTKIIGNCVSILVLSSALPVMSRTLGITRFDLLGDFGRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVGFYSLRFFGNFTPKKDDTTMTKIIGNCVSILVLSSALPVMSRTLGITRFDLLGDFGRF 220 230 240 250 260 270 430 440 450 460 470 480 pF1KB8 NWLGNFYIVLSYNLLFAIVTTLCLVRKFASAVREELFKALGLHKLHLPNTSRDSETAKPS ::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::: XP_016 NWLGNFYIVLSYNLLFAIVTTLCLVRKFTSAVREELFKALGLHKLHLPNTSRDSETAKPS 280 290 300 310 320 330 490 pF1KB8 VNGHQKAL :::::::: XP_016 VNGHQKAL >>XP_016868005 (OMIM: 135750,174500,186200,188740,200500 (343 aa) initn: 1938 init1: 1915 opt: 1915 Z-score: 2331.6 bits: 440.4 E(85289): 3.9e-123 Smith-Waterman score: 1967; 85.6% identity (85.9% similar) in 383 aa overlap (108-490:15-343) 80 90 100 110 120 130 pF1KB8 LPFSIISNEILLSFPQNYYIQWLNGSLIHGLWNLASLFSNLCLFVLMPFAFFFLESEGFA :::::::::::::::::::::::::::::: XP_016 MNKKMKMPSSTGFRLWNLASLFSNLCLFVLMPFAFFFLESEGFA 10 20 30 40 140 150 160 170 180 190 pF1KB8 GLKKGIRARILETLVMLLLLALLILGIVWVASALIDNDAASMESLYDLWEFYLPYLYSCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLKKGIRARILETLVMLLLLALLILGIVWVASALIDNDAASMESLYDLWEFYLPYLYSCI 50 60 70 80 90 100 200 210 220 230 240 250 pF1KB8 SLMGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYIITLEEEALQRRLNGLSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLMGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYIITLEEEALQRRLNGLSSS 110 120 130 140 150 160 260 270 280 290 300 310 pF1KB8 VEYNIMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVLLLIETSISALLVACNIL :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: XP_016 VEYNIMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVLLLIETSISVLLVACNIL 170 180 190 200 210 220 320 330 340 350 360 370 pF1KB8 CLLVDETAMPKGTRGPGIGNASLSTFGFVGAALEIILIFYLMVSSVVGFYSLRFFGNFTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLLVDETAMPKGTRGPGIGNASLSTFGFVGAALEIILIFYLMVSSVVGFYSLRFFGNFTP 230 240 250 260 270 280 380 390 400 410 420 430 pF1KB8 KKDDTTMTKIIGNCVSILVLSSALPVMSRTLGITRFDLLGDFGRFNWLGNFYIVLSYNLL :::::::::::::::::::::::::::::::: XP_016 KKDDTTMTKIIGNCVSILVLSSALPVMSRTLG---------------------------- 290 300 310 440 450 460 470 480 490 pF1KB8 FAIVTTLCLVRKFASAVREELFKALGLHKLHLPNTSRDSETAKPSVNGHQKAL ::::::::::::::::::::::::::: XP_016 --------------------------LHKLHLPNTSRDSETAKPSVNGHQKAL 320 330 340 >>NP_060583 (OMIM: 610007) protein LMBR1L isoform 1 [Hom (489 aa) initn: 1783 init1: 978 opt: 1902 Z-score: 2313.3 bits: 437.5 E(85289): 4.1e-122 Smith-Waterman score: 1902; 61.3% identity (84.2% similar) in 475 aa overlap (1-470:1-475) 10 20 30 40 50 pF1KB8 MEGQD-EV-SAREQHFHSQVRESTICFLLFAILYVVSYFIITRYKRKSDEQ--EDEDAIV ::. : :: :.::: :: ..:: : :::: ::.. ....::.:. .. .:::: : NP_060 MEAPDYEVLSVREQLFHERIRECIISTLLFATLYILCHIFLTRFKKPAEFTTVDDEDATV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 NRISLFLSTFTLAVSAGAVLLLPFSIISNEILLSFPQNYYIQWLNGSLIHGLWNLASLFS :.:.: : :::::.. ::::::::::::::.:::.:.::::::::::::::::::. ::: NP_060 NKIALELCTFTLAIALGAVLLLPFSIISNEVLLSLPRNYYIQWLNGSLIHGLWNLVFLFS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 NLCLFVLMPFAFFFLESEGFAGLKKGIRARILETLVMLLLLALLILGIVWVASALIDNDA :: :. :::::.:: ::::::: .::. .:. ::.:::.::.::.::.::::::..:.. NP_060 NLSLIFLMPFAYFFTESEGFAGSRKGVLGRVYETVVMLMLLTLLVLGMVWVASAIVDKNK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 ASMESLYDLWEFYLPYLYSCISLMGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQ :. :::::.::.::::::::::..: ::::.:::.::.:::.: :.::::: .::::.:: NP_060 ANRESLYDFWEYYLPYLYSCISFLGVLLLLVCTPLGLARMFSVTGKLLVKPRLLEDLEEQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 IYIITLEEEALQRRL-NGLSSSVEYNIMELEQELENVKTLKTKLERRKKASAWERNLVYP .: ..:: :: ::. : : . .. :.... ..: .. ::.:.:::::.::: :: NP_060 LYCSAFEEAALTRRICNPTSCWLPLDMELLHRQVLALQTQRVLLEKRRKASAWQRNLGYP 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 AVMVLLLIETSISALLVACNILCLLVDETAMPKGTRGPGIGNASLSTFGFVGAALEIILI .:. ::. :..:.:.:: .:: ::.::.:::.: .: ..:..:.: .: ::.....:: NP_060 LAMLCLLVLTGLSVLIVAIHILELLIDEAAMPRGMQGTSLGQVSFSKLGSFGAVIQVVLI 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 FYLMVSSVVGFYSLRFFGNFTPKKDDTTMTKIIGNCVSILVLSSALPVMSRTLGITRFDL ::::::::::::: .: .. :. ::.::.:::::: .:::::::::.:::::.::::: NP_060 FYLMVSSVVGFYSSPLFRSLRPRWHDTAMTQIIGNCVCLLVLSSALPVFSRTLGLTRFDL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 LGDFGRFNWLGNFYIVLSYNLLFAIVTTLCLVRKFASAVREELFKALGLHKLHLPNTSRD ::::::::::::::::. :: :: .::::::. :..::: ::..:.:: .: :: NP_060 LGDFGRFNWLGNFYIVFLYNAAFAGLTTLCLVKTFTAAVRAELIRAFGLDRLPLPVSGFP 430 440 450 460 470 480 480 490 pF1KB8 SETAKPSVNGHQKAL NP_060 QASRKTQHQ >>XP_011536866 (OMIM: 610007) PREDICTED: protein LMBR1L (450 aa) initn: 1783 init1: 978 opt: 1786 Z-score: 2172.8 bits: 411.4 E(85289): 2.8e-114 Smith-Waterman score: 1786; 63.5% identity (86.0% similar) in 422 aa overlap (50-470:15-436) 20 30 40 50 60 70 pF1KB8 ESTICFLLFAILYVVSYFIITRYKRKSDEQEDEDAIVNRISLFLSTFTLAVSAGAVLLLP .:::: ::.:.: : :::::.. ::::::: XP_011 MSSCLFPVPLSLTVDDEDATVNKIALELCTFTLAIALGAVLLLP 10 20 30 40 80 90 100 110 120 130 pF1KB8 FSIISNEILLSFPQNYYIQWLNGSLIHGLWNLASLFSNLCLFVLMPFAFFFLESEGFAGL :::::::.:::.:.::::::::::::::::::. ::::: :. :::::.:: ::::::: XP_011 FSIISNEVLLSLPRNYYIQWLNGSLIHGLWNLVFLFSNLSLIFLMPFAYFFTESEGFAGS 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB8 KKGIRARILETLVMLLLLALLILGIVWVASALIDNDAASMESLYDLWEFYLPYLYSCISL .::. .:. ::.:::.::.::.::.::::::..:.. :. :::::.::.::::::::::. XP_011 RKGVLGRVYETVVMLMLLTLLVLGMVWVASAIVDKNKANRESLYDFWEYYLPYLYSCISF 110 120 130 140 150 160 200 210 220 230 240 250 pF1KB8 MGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYIITLEEEALQRRL-NGLSSSV .: ::::.:::.::.:::.: :.::::: .::::.::.: ..:: :: ::. : : . XP_011 LGVLLLLVCTPLGLARMFSVTGKLLVKPRLLEDLEEQLYCSAFEEAALTRRICNPTSCWL 170 180 190 200 210 220 260 270 280 290 300 310 pF1KB8 EYNIMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVLLLIETSISALLVACNILC .. :.... ..: .. ::.:.:::::.::: :: .:. ::. :..:.:.:: .:: XP_011 PLDMELLHRQVLALQTQRVLLEKRRKASAWQRNLGYPLAMLCLLVLTGLSVLIVAIHILE 230 240 250 260 270 280 320 330 340 350 360 370 pF1KB8 LLVDETAMPKGTRGPGIGNASLSTFGFVGAALEIILIFYLMVSSVVGFYSLRFFGNFTPK ::.::.:::.: .: ..:..:.: .: ::.....::::::::::::::: .: .. :. XP_011 LLIDEAAMPRGMQGTSLGQVSFSKLGSFGAVIQVVLIFYLMVSSVVGFYSSPLFRSLRPR 290 300 310 320 330 340 380 390 400 410 420 430 pF1KB8 KDDTTMTKIIGNCVSILVLSSALPVMSRTLGITRFDLLGDFGRFNWLGNFYIVLSYNLLF ::.::.:::::: .:::::::::.:::::.:::::::::::::::::::::. :: : XP_011 WHDTAMTQIIGNCVCLLVLSSALPVFSRTLGLTRFDLLGDFGRFNWLGNFYIVFLYNAAF 350 360 370 380 390 400 440 450 460 470 480 490 pF1KB8 AIVTTLCLVRKFASAVREELFKALGLHKLHLPNTSRDSETAKPSVNGHQKAL : .::::::. :..::: ::..:.:: .: :: XP_011 AGLTTLCLVKTFTAAVRAELIRAFGLDRLPLPVSGFPQASRKTQHQ 410 420 430 440 450 >>XP_016875115 (OMIM: 610007) PREDICTED: protein LMBR1L (484 aa) initn: 1783 init1: 978 opt: 1786 Z-score: 2172.3 bits: 411.4 E(85289): 2.9e-114 Smith-Waterman score: 1786; 63.5% identity (86.0% similar) in 422 aa overlap (50-470:49-470) 20 30 40 50 60 70 pF1KB8 ESTICFLLFAILYVVSYFIITRYKRKSDEQEDEDAIVNRISLFLSTFTLAVSAGAVLLLP .:::: ::.:.: : :::::.. ::::::: XP_016 VITGTGSVSSPLLVLPQPGPETSLMTGEPVDDEDATVNKIALELCTFTLAIALGAVLLLP 20 30 40 50 60 70 80 90 100 110 120 130 pF1KB8 FSIISNEILLSFPQNYYIQWLNGSLIHGLWNLASLFSNLCLFVLMPFAFFFLESEGFAGL :::::::.:::.:.::::::::::::::::::. ::::: :. :::::.:: ::::::: XP_016 FSIISNEVLLSLPRNYYIQWLNGSLIHGLWNLVFLFSNLSLIFLMPFAYFFTESEGFAGS 80 90 100 110 120 130 140 150 160 170 180 190 pF1KB8 KKGIRARILETLVMLLLLALLILGIVWVASALIDNDAASMESLYDLWEFYLPYLYSCISL .::. .:. ::.:::.::.::.::.::::::..:.. :. :::::.::.::::::::::. XP_016 RKGVLGRVYETVVMLMLLTLLVLGMVWVASAIVDKNKANRESLYDFWEYYLPYLYSCISF 140 150 160 170 180 190 200 210 220 230 240 250 pF1KB8 MGCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYIITLEEEALQRRL-NGLSSSV .: ::::.:::.::.:::.: :.::::: .::::.::.: ..:: :: ::. : : . XP_016 LGVLLLLVCTPLGLARMFSVTGKLLVKPRLLEDLEEQLYCSAFEEAALTRRICNPTSCWL 200 210 220 230 240 250 260 270 280 290 300 310 pF1KB8 EYNIMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVLLLIETSISALLVACNILC .. :.... ..: .. ::.:.:::::.::: :: .:. ::. :..:.:.:: .:: XP_016 PLDMELLHRQVLALQTQRVLLEKRRKASAWQRNLGYPLAMLCLLVLTGLSVLIVAIHILE 260 270 280 290 300 310 320 330 340 350 360 370 pF1KB8 LLVDETAMPKGTRGPGIGNASLSTFGFVGAALEIILIFYLMVSSVVGFYSLRFFGNFTPK ::.::.:::.: .: ..:..:.: .: ::.....::::::::::::::: .: .. :. XP_016 LLIDEAAMPRGMQGTSLGQVSFSKLGSFGAVIQVVLIFYLMVSSVVGFYSSPLFRSLRPR 320 330 340 350 360 370 380 390 400 410 420 430 pF1KB8 KDDTTMTKIIGNCVSILVLSSALPVMSRTLGITRFDLLGDFGRFNWLGNFYIVLSYNLLF ::.::.:::::: .:::::::::.:::::.:::::::::::::::::::::. :: : XP_016 WHDTAMTQIIGNCVCLLVLSSALPVFSRTLGLTRFDLLGDFGRFNWLGNFYIVFLYNAAF 380 390 400 410 420 430 440 450 460 470 480 490 pF1KB8 AIVTTLCLVRKFASAVREELFKALGLHKLHLPNTSRDSETAKPSVNGHQKAL : .::::::. :..::: ::..:.:: .: :: XP_016 AGLTTLCLVKTFTAAVRAELIRAFGLDRLPLPVSGFPQASRKTQHQ 440 450 460 470 480 490 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:46:58 2016 done: Fri Nov 4 14:47:00 2016 Total Scan time: 9.350 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]