Result of FASTA (omim) for
pF1KB8707
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8707, 539 aa
1>>>pF1KB8707 539 - 539 aa - 539 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1963+/-0.000363; mu= 16.5917+/- 0.023
mean_var=138.8274+/-27.887, 0's: 0 Z-trim(117.5): 18 B-trim: 293 in 2/54
Lambda= 0.108852
statistics sampled from 29590 (29608) to 29590 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.347), width: 16
Scan time: 10.500
The best scores are: opt bits E(85289)
NP_001013456 (OMIM: 600819) fragile X mental retar ( 539) 3571 572.6 1.1e-162
NP_005078 (OMIM: 600819) fragile X mental retardat ( 621) 3529 566.0 1.1e-160
XP_005247872 (OMIM: 600819) PREDICTED: fragile X m ( 648) 3529 566.1 1.2e-160
XP_016862790 (OMIM: 600819) PREDICTED: fragile X m ( 454) 2976 479.1 1.3e-134
NP_001013457 (OMIM: 600819) fragile X mental retar ( 536) 2934 472.5 1.4e-132
XP_016862788 (OMIM: 600819) PREDICTED: fragile X m ( 563) 2934 472.6 1.4e-132
XP_005247873 (OMIM: 600819) PREDICTED: fragile X m ( 568) 2522 407.9 4.3e-113
XP_005247871 (OMIM: 600819) PREDICTED: fragile X m ( 650) 2522 407.9 4.8e-113
XP_005247870 (OMIM: 600819) PREDICTED: fragile X m ( 677) 2522 407.9 4.9e-113
NP_004851 (OMIM: 605339) fragile X mental retardat ( 673) 2010 327.5 7.8e-89
XP_016862789 (OMIM: 600819) PREDICTED: fragile X m ( 483) 1927 314.3 5.2e-85
XP_016862787 (OMIM: 600819) PREDICTED: fragile X m ( 565) 1927 314.4 5.8e-85
XP_006713838 (OMIM: 600819) PREDICTED: fragile X m ( 592) 1927 314.4 6e-85
NP_001172005 (OMIM: 300623,300624,309550,311360) s ( 611) 1689 277.1 1.1e-73
NP_001172010 (OMIM: 300623,300624,309550,311360) s ( 516) 1670 274.0 7.7e-73
NP_001172004 (OMIM: 300623,300624,309550,311360) s ( 537) 1670 274.0 7.9e-73
NP_001172011 (OMIM: 300623,300624,309550,311360) s ( 586) 1670 274.1 8.4e-73
NP_002015 (OMIM: 300623,300624,309550,311360) syna ( 632) 1670 274.1 8.8e-73
>>NP_001013456 (OMIM: 600819) fragile X mental retardati (539 aa)
initn: 3571 init1: 3571 opt: 3571 Z-score: 3041.9 bits: 572.6 E(85289): 1.1e-162
Smith-Waterman score: 3571; 100.0% identity (100.0% similar) in 539 aa overlap (1-539:1-539)
10 20 30 40 50 60
pF1KB8 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL
430 440 450 460 470 480
490 500 510 520 530
pF1KB8 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLGKRCD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLGKRCD
490 500 510 520 530
>>NP_005078 (OMIM: 600819) fragile X mental retardation (621 aa)
initn: 3529 init1: 3529 opt: 3529 Z-score: 3005.5 bits: 566.0 E(85289): 1.1e-160
Smith-Waterman score: 3529; 100.0% identity (100.0% similar) in 534 aa overlap (1-534:1-534)
10 20 30 40 50 60
pF1KB8 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL
430 440 450 460 470 480
490 500 510 520 530
pF1KB8 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLGKRCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADY
490 500 510 520 530 540
NP_005 ISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGE
550 560 570 580 590 600
>>XP_005247872 (OMIM: 600819) PREDICTED: fragile X menta (648 aa)
initn: 3529 init1: 3529 opt: 3529 Z-score: 3005.2 bits: 566.1 E(85289): 1.2e-160
Smith-Waterman score: 3529; 100.0% identity (100.0% similar) in 534 aa overlap (1-534:1-534)
10 20 30 40 50 60
pF1KB8 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL
430 440 450 460 470 480
490 500 510 520 530
pF1KB8 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLGKRCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLDDSEKK
490 500 510 520 530 540
XP_005 PQRRNRSRRRRFRGQAEDRQPVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEH
550 560 570 580 590 600
>>XP_016862790 (OMIM: 600819) PREDICTED: fragile X menta (454 aa)
initn: 2976 init1: 2976 opt: 2976 Z-score: 2537.8 bits: 479.1 E(85289): 1.3e-134
Smith-Waterman score: 2976; 100.0% identity (100.0% similar) in 454 aa overlap (86-539:1-454)
60 70 80 90 100 110
pF1KB8 KKEISEGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPV
::::::::::::::::::::::::::::::
XP_016 MMKGEFYVIEYAACDATYNEIVTFERLRPV
10 20 30
120 130 140 150 160 170
pF1KB8 NQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASE
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB8 ATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIG
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB8 THGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGK
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB8 VIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHI
220 230 240 250 260 270
360 370 380 390 400 410
pF1KB8 AYLKEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYLKEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESER
280 290 300 310 320 330
420 430 440 450 460 470
pF1KB8 KDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSN
340 350 360 370 380 390
480 490 500 510 520 530
pF1KB8 PYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLG
400 410 420 430 440 450
pF1KB8 KRCD
::::
XP_016 KRCD
>>NP_001013457 (OMIM: 600819) fragile X mental retardati (536 aa)
initn: 2934 init1: 2934 opt: 2934 Z-score: 2501.3 bits: 472.5 E(85289): 1.4e-132
Smith-Waterman score: 2934; 100.0% identity (100.0% similar) in 449 aa overlap (86-534:1-449)
60 70 80 90 100 110
pF1KB8 KKEISEGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPV
::::::::::::::::::::::::::::::
NP_001 MMKGEFYVIEYAACDATYNEIVTFERLRPV
10 20 30
120 130 140 150 160 170
pF1KB8 NQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASE
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB8 ATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIG
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB8 THGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGK
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB8 VIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHI
220 230 240 250 260 270
360 370 380 390 400 410
pF1KB8 AYLKEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYLKEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESER
280 290 300 310 320 330
420 430 440 450 460 470
pF1KB8 KDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSN
340 350 360 370 380 390
480 490 500 510 520 530
pF1KB8 PYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLV
400 410 420 430 440 450
pF1KB8 KRCD
NP_001 TVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQ
460 470 480 490 500 510
>>XP_016862788 (OMIM: 600819) PREDICTED: fragile X menta (563 aa)
initn: 2934 init1: 2934 opt: 2934 Z-score: 2501.0 bits: 472.6 E(85289): 1.4e-132
Smith-Waterman score: 2934; 100.0% identity (100.0% similar) in 449 aa overlap (86-534:1-449)
60 70 80 90 100 110
pF1KB8 KKEISEGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPV
::::::::::::::::::::::::::::::
XP_016 MMKGEFYVIEYAACDATYNEIVTFERLRPV
10 20 30
120 130 140 150 160 170
pF1KB8 NQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASE
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB8 ATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIG
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB8 THGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGK
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB8 VIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHI
220 230 240 250 260 270
360 370 380 390 400 410
pF1KB8 AYLKEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYLKEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESER
280 290 300 310 320 330
420 430 440 450 460 470
pF1KB8 KDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSN
340 350 360 370 380 390
480 490 500 510 520 530
pF1KB8 PYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLD
400 410 420 430 440 450
pF1KB8 KRCD
XP_016 DSEKKPQRRNRSRRRRFRGQAEDRQPVTVADYISRAESQSRQRNLPRETLAKNKKEMAKD
460 470 480 490 500 510
>>XP_005247873 (OMIM: 600819) PREDICTED: fragile X menta (568 aa)
initn: 2629 init1: 2496 opt: 2522 Z-score: 2151.3 bits: 407.9 E(85289): 4.3e-113
Smith-Waterman score: 3503; 94.9% identity (94.9% similar) in 568 aa overlap (1-539:1-568)
10 20 30 40 50 60
pF1KB8 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE
310 320 330 340 350 360
370 380 390
pF1KB8 VEQLRMERLQIDEQLRQIG-----------------------------SRSYSGRGRGRR
::::::::::::::::::: ::::::::::::
XP_005 VEQLRMERLQIDEQLRQIGMGFRPSSTRGPEKEKGYATDESTVSSVQGSRSYSGRGRGRR
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB8 GPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSG
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB8 GRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRT
490 500 510 520 530 540
520 530
pF1KB8 DEDAVLMDGMTESDTASVNENGLGKRCD
::::::::::::::::::::::::::::
XP_005 DEDAVLMDGMTESDTASVNENGLGKRCD
550 560
>>XP_005247871 (OMIM: 600819) PREDICTED: fragile X menta (650 aa)
initn: 2629 init1: 2496 opt: 2522 Z-score: 2150.6 bits: 407.9 E(85289): 4.8e-113
Smith-Waterman score: 3461; 94.8% identity (94.8% similar) in 563 aa overlap (1-534:1-563)
10 20 30 40 50 60
pF1KB8 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE
310 320 330 340 350 360
370 380 390
pF1KB8 VEQLRMERLQIDEQLRQIG-----------------------------SRSYSGRGRGRR
::::::::::::::::::: ::::::::::::
XP_005 VEQLRMERLQIDEQLRQIGMGFRPSSTRGPEKEKGYATDESTVSSVQGSRSYSGRGRGRR
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB8 GPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSG
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB8 GRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRT
490 500 510 520 530 540
520 530
pF1KB8 DEDAVLMDGMTESDTASVNENGLGKRCD
:::::::::::::::::::::::
XP_005 DEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIE
550 560 570 580 590 600
>>XP_005247870 (OMIM: 600819) PREDICTED: fragile X menta (677 aa)
initn: 2599 init1: 2496 opt: 2522 Z-score: 2150.4 bits: 407.9 E(85289): 4.9e-113
Smith-Waterman score: 3461; 94.8% identity (94.8% similar) in 563 aa overlap (1-534:1-563)
10 20 30 40 50 60
pF1KB8 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE
310 320 330 340 350 360
370 380 390
pF1KB8 VEQLRMERLQIDEQLRQIG-----------------------------SRSYSGRGRGRR
::::::::::::::::::: ::::::::::::
XP_005 VEQLRMERLQIDEQLRQIGMGFRPSSTRGPEKEKGYATDESTVSSVQGSRSYSGRGRGRR
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB8 GPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSG
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB8 GRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRT
490 500 510 520 530 540
520 530
pF1KB8 DEDAVLMDGMTESDTASVNENGLGKRCD
:::::::::::::::::::::::
XP_005 DEDAVLMDGMTESDTASVNENGLDDSEKKPQRRNRSRRRRFRGQAEDRQPVTVADYISRA
550 560 570 580 590 600
>>NP_004851 (OMIM: 605339) fragile X mental retardation (673 aa)
initn: 2365 init1: 1985 opt: 2010 Z-score: 1715.8 bits: 327.5 E(85289): 7.8e-89
Smith-Waterman score: 2364; 65.3% identity (81.1% similar) in 577 aa overlap (4-534:14-576)
10 20 30 40 50
pF1KB8 MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLP
: ::::::::::::::.:::::::.:. :::::: :::.::..::::
NP_004 MGGLASGGDVEPGLPVEVRGSNGAFYKGFVKDVHEDSVTIFFENNWQSERQIPFGDVRLP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 PPPDIKKEISEGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFE
:: : .:::.::::::::::::.:::::::::.::::::.::::::::::::::::::.:
NP_004 PPADYNKEITEGDEVEVYSRANEQEPCGWWLARVRMMKGDFYVIEYAACDATYNEIVTLE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 RLRPVNQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMI
:::::: : . :..::: :. :::::::::.:::.::.::::.:: :: . ...:.:
NP_004 RLRPVNPNPLATKGSFFKVTMAVPEDLREACSNENVHKEFKKALGANCIFLNITNSELFI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 LSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLM
::..:: :::...:.:::.::.::::.::::::::::::: .:::::::.:::.::::::
NP_004 LSTTEAPVKRASLLGDMHFRSLRTKLLLMSRNEEATKHLETSKQLAAAFQEEFTVREDLM
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 GLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPR
::::::::.:::::::::::::::: :.: :::::::. .: ..::..::: :: .::::
NP_004 GLAIGTHGANIQQARKVPGVTAIELGEETCTFRIYGETPEACRQARSYLEFSEDSVQVPR
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 NLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVL
:::::::::::::::::::::::::::.::::..: :::.:::::.::::.:.:.:.:.:
NP_004 NLVGKVIGKNGKVIQEIVDKSGVVRVRVEGDNDKKNPREEGMVPFIFVGTRENISNAQAL
310 320 330 340 350 360
360 370
pF1KB8 LEYHIAYLKEVEQLRMERLQIDEQLRQIG-------------------------------
::::..::.::::::.:::::::::::::
NP_004 LEYHLSYLQEVEQLRLERLQIDEQLRQIGLGFRPPGSGRGSGGSDKAGYSTDESSSSSLH
370 380 390 400 410 420
380 390 400 410 420 430
pF1KB8 -SR----SYSGRGRGRR--GPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDS
.: ::.::::::: :: .:: .:..:. ::::::...: . :: :::
NP_004 ATRTYGGSYGGRGRGRRTGGP----AYGPSSDVSTASETESEKREEPNR---AGPGDRDP
430 440 450 460 470
440 450 460 470 480
pF1KB8 -RHQRDSRRRPGGRGRSVSGGRGRGGP-------RGGKSSISSVLKDPDSNPYSLLDNTE
. ..::::: .:::::: : : ..:::::::::::::::::::..:
NP_004 PTRGEESRRRP-------TGGRGRGPPPAPRPTSRYNSSSISSVLKDPDSNPYSLLDTSE
480 490 500 510 520
490 500 510 520 530
pF1KB8 SDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLGKRCD
. .:.. .: .. ::::::::::::: ..::: ::: ...::::
NP_004 PEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLESDGPNMTENGLEDESRPQRRN
530 540 550 560 570 580
NP_004 RSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQSRQRPPLERTKPSEDSLSGQKGDSV
590 600 610 620 630 640
539 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:47:40 2016 done: Fri Nov 4 14:47:41 2016
Total Scan time: 10.500 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]