FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8711, 482 aa 1>>>pF1KB8711 482 - 482 aa - 482 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8167+/-0.000934; mu= 11.4007+/- 0.056 mean_var=102.6412+/-20.183, 0's: 0 Z-trim(107.5): 22 B-trim: 2 in 1/49 Lambda= 0.126594 statistics sampled from 9584 (9597) to 9584 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.666), E-opt: 0.2 (0.295), width: 16 Scan time: 2.910 The best scores are: opt bits E(32554) CCDS64595.1 ICA1 gene_id:3382|Hs108|chr7 ( 482) 3204 595.8 3.3e-170 CCDS34602.1 ICA1 gene_id:3382|Hs108|chr7 ( 483) 3192 593.6 1.5e-169 CCDS2354.1 ICA1L gene_id:130026|Hs108|chr2 ( 482) 1335 254.5 1.9e-67 CCDS74632.1 ICA1L gene_id:130026|Hs108|chr2 ( 187) 833 162.6 3.3e-40 >>CCDS64595.1 ICA1 gene_id:3382|Hs108|chr7 (482 aa) initn: 3204 init1: 3204 opt: 3204 Z-score: 3169.2 bits: 595.8 E(32554): 3.3e-170 Smith-Waterman score: 3204; 100.0% identity (100.0% similar) in 482 aa overlap (1-482:1-482) 10 20 30 40 50 60 pF1KB8 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL 430 440 450 460 470 480 pF1KB8 NA :: CCDS64 NA >>CCDS34602.1 ICA1 gene_id:3382|Hs108|chr7 (483 aa) initn: 3190 init1: 3155 opt: 3192 Z-score: 3157.4 bits: 593.6 E(32554): 1.5e-169 Smith-Waterman score: 3192; 99.8% identity (99.8% similar) in 483 aa overlap (1-482:1-483) 10 20 30 40 50 pF1KB8 MSGHKC-YPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL :::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL 430 440 450 460 470 480 480 pF1KB8 LNA ::: CCDS34 LNA >>CCDS2354.1 ICA1L gene_id:130026|Hs108|chr2 (482 aa) initn: 1378 init1: 1212 opt: 1335 Z-score: 1324.4 bits: 254.5 E(32554): 1.9e-67 Smith-Waterman score: 1377; 49.5% identity (71.9% similar) in 501 aa overlap (12-482:6-482) 10 20 30 40 50 60 pF1KB8 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE : : ...::: .::.:::.:::.::::::::::::.:::::.:::::: CCDS23 MDSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLE 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC .:::.:.:: .: : : :: :. .:.:::::: ::. :. .: :.:::::.::::::: CCDS23 VFHSVQETCTELLKIIEKYQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALC 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD :..::::: .:: :..::: :: .::.::: .:.::::: ::::::::::::::::::: CCDS23 SSAKQRLALCTPLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELD 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF :: :::::::::: ::: .: .:::::::::::::::::::::.::: :.::: ::: : CCDS23 PDTLKQMEKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGF 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ :.::.. :. :::. :..::.:..::.::: .:. : .. ..:. ... .. CCDS23 WKKTARMMSQIHEACIGFHPYDFVALKQLQDTPSKISEDNKDEQIG-----GFLTEQLNK 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG :. .:: .::..:.... . .: : ..: .. . ::. : :: . CCDS23 LVLSDEE------ASFESEQANKDHN--EKHSQMREFGAP--QFSN--SENVAKDLPVDS 290 300 310 320 330 370 380 390 400 410 pF1KB8 TPEPEGAD-KDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ :: : . .. .:.......: .::..: ..::. ... ..: .: :. CCDS23 L---EGEDFEKEFSFLNNLLSSGSSSTSEFTQECQTAFGSPSASLTSQEPSMGS-EPLAH 340 350 360 370 380 390 420 430 440 450 pF1KB8 TGSGFLPSQLLD--------------QNMKDLQASL--------QEPAK-------AASD . : ::::::.: :. ..: : : : : . .: CCDS23 S-SRFLPSQLFDLGFHVAGAFNNWVSQEESELCLSHTDNQPVPSQSPKKLTRSPNNGNQD 400 410 420 430 440 450 460 470 480 pF1KB8 LTAWFSLFADLDPLSNPDAVGKTDKEHELLNA ..:::.:::::::::::::.:..: : :::: CCDS23 MSAWFNLFADLDPLSNPDAIGHSDDE--LLNA 460 470 480 >>CCDS74632.1 ICA1L gene_id:130026|Hs108|chr2 (187 aa) initn: 833 init1: 833 opt: 833 Z-score: 835.3 bits: 162.6 E(32554): 3.3e-40 Smith-Waterman score: 833; 69.8% identity (86.3% similar) in 182 aa overlap (12-193:6-187) 10 20 30 40 50 60 pF1KB8 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE : : ...::: .::.:::.:::.::::::::::::.:::::.:::::: CCDS74 MDSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLE 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC .:::.:.:: .: : : :: :. .:.:::::: ::. :. .: :.:::::.::::::: CCDS74 VFHSVQETCTELLKIIEKYQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALC 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD :..::::: .:: :..::: :: .::.::: .:.::::: ::::::::::::::::::: CCDS74 SSAKQRLALCTPLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELD 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF :: ::::::::: CCDS74 PDTLKQMEKFRKV 180 482 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:34:29 2016 done: Sat Nov 5 21:34:30 2016 Total Scan time: 2.910 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]