FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8723, 509 aa 1>>>pF1KB8723 509 - 509 aa - 509 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5304+/-0.000391; mu= 17.4801+/- 0.024 mean_var=80.3100+/-16.267, 0's: 0 Z-trim(113.1): 47 B-trim: 0 in 0/52 Lambda= 0.143116 statistics sampled from 22279 (22320) to 22279 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.623), E-opt: 0.2 (0.262), width: 16 Scan time: 10.200 The best scores are: opt bits E(85289) NP_996839 (OMIM: 606021) melanoma antigen preferen ( 509) 3381 708.1 1.5e-203 NP_996838 (OMIM: 606021) melanoma antigen preferen ( 509) 3381 708.1 1.5e-203 NP_001278644 (OMIM: 606021) melanoma antigen prefe ( 509) 3381 708.1 1.5e-203 NP_996837 (OMIM: 606021) melanoma antigen preferen ( 509) 3381 708.1 1.5e-203 NP_001278645 (OMIM: 606021) melanoma antigen prefe ( 509) 3381 708.1 1.5e-203 NP_006106 (OMIM: 606021) melanoma antigen preferen ( 509) 3381 708.1 1.5e-203 NP_996836 (OMIM: 606021) melanoma antigen preferen ( 509) 3381 708.1 1.5e-203 NP_001278646 (OMIM: 606021) melanoma antigen prefe ( 493) 3290 689.3 6.7e-198 NP_001305055 (OMIM: 606021) melanoma antigen prefe ( 493) 3290 689.3 6.7e-198 NP_001278648 (OMIM: 606021) melanoma antigen prefe ( 493) 3290 689.3 6.7e-198 XP_011528336 (OMIM: 606021) PREDICTED: melanoma an ( 493) 3290 689.3 6.7e-198 NP_001305056 (OMIM: 606021) melanoma antigen prefe ( 493) 3290 689.3 6.7e-198 NP_703148 (OMIM: 609658) NACHT, LRR and PYD domain (1200) 156 42.5 0.0084 >>NP_996839 (OMIM: 606021) melanoma antigen preferential (509 aa) initn: 3381 init1: 3381 opt: 3381 Z-score: 3775.3 bits: 708.1 E(85289): 1.5e-203 Smith-Waterman score: 3381; 99.8% identity (99.8% similar) in 509 aa overlap (1-509:1-509) 10 20 30 40 50 60 pF1KB8 MERRRLRGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA :::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 430 440 450 460 470 480 490 500 pF1KB8 WLSANPCPHCGDRTFYDPEPILCPCFMPN ::::::::::::::::::::::::::::: NP_996 WLSANPCPHCGDRTFYDPEPILCPCFMPN 490 500 >>NP_996838 (OMIM: 606021) melanoma antigen preferential (509 aa) initn: 3381 init1: 3381 opt: 3381 Z-score: 3775.3 bits: 708.1 E(85289): 1.5e-203 Smith-Waterman score: 3381; 99.8% identity (99.8% similar) in 509 aa overlap (1-509:1-509) 10 20 30 40 50 60 pF1KB8 MERRRLRGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA :::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 430 440 450 460 470 480 490 500 pF1KB8 WLSANPCPHCGDRTFYDPEPILCPCFMPN ::::::::::::::::::::::::::::: NP_996 WLSANPCPHCGDRTFYDPEPILCPCFMPN 490 500 >>NP_001278644 (OMIM: 606021) melanoma antigen preferent (509 aa) initn: 3381 init1: 3381 opt: 3381 Z-score: 3775.3 bits: 708.1 E(85289): 1.5e-203 Smith-Waterman score: 3381; 99.8% identity (99.8% similar) in 509 aa overlap (1-509:1-509) 10 20 30 40 50 60 pF1KB8 MERRRLRGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA :::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 430 440 450 460 470 480 490 500 pF1KB8 WLSANPCPHCGDRTFYDPEPILCPCFMPN ::::::::::::::::::::::::::::: NP_001 WLSANPCPHCGDRTFYDPEPILCPCFMPN 490 500 >>NP_996837 (OMIM: 606021) melanoma antigen preferential (509 aa) initn: 3381 init1: 3381 opt: 3381 Z-score: 3775.3 bits: 708.1 E(85289): 1.5e-203 Smith-Waterman score: 3381; 99.8% identity (99.8% similar) in 509 aa overlap (1-509:1-509) 10 20 30 40 50 60 pF1KB8 MERRRLRGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA :::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 430 440 450 460 470 480 490 500 pF1KB8 WLSANPCPHCGDRTFYDPEPILCPCFMPN ::::::::::::::::::::::::::::: NP_996 WLSANPCPHCGDRTFYDPEPILCPCFMPN 490 500 >>NP_001278645 (OMIM: 606021) melanoma antigen preferent (509 aa) initn: 3381 init1: 3381 opt: 3381 Z-score: 3775.3 bits: 708.1 E(85289): 1.5e-203 Smith-Waterman score: 3381; 99.8% identity (99.8% similar) in 509 aa overlap (1-509:1-509) 10 20 30 40 50 60 pF1KB8 MERRRLRGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA :::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 430 440 450 460 470 480 490 500 pF1KB8 WLSANPCPHCGDRTFYDPEPILCPCFMPN ::::::::::::::::::::::::::::: NP_001 WLSANPCPHCGDRTFYDPEPILCPCFMPN 490 500 >>NP_006106 (OMIM: 606021) melanoma antigen preferential (509 aa) initn: 3381 init1: 3381 opt: 3381 Z-score: 3775.3 bits: 708.1 E(85289): 1.5e-203 Smith-Waterman score: 3381; 99.8% identity (99.8% similar) in 509 aa overlap (1-509:1-509) 10 20 30 40 50 60 pF1KB8 MERRRLRGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA :::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 430 440 450 460 470 480 490 500 pF1KB8 WLSANPCPHCGDRTFYDPEPILCPCFMPN ::::::::::::::::::::::::::::: NP_006 WLSANPCPHCGDRTFYDPEPILCPCFMPN 490 500 >>NP_996836 (OMIM: 606021) melanoma antigen preferential (509 aa) initn: 3381 init1: 3381 opt: 3381 Z-score: 3775.3 bits: 708.1 E(85289): 1.5e-203 Smith-Waterman score: 3381; 99.8% identity (99.8% similar) in 509 aa overlap (1-509:1-509) 10 20 30 40 50 60 pF1KB8 MERRRLRGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA :::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 430 440 450 460 470 480 490 500 pF1KB8 WLSANPCPHCGDRTFYDPEPILCPCFMPN ::::::::::::::::::::::::::::: NP_996 WLSANPCPHCGDRTFYDPEPILCPCFMPN 490 500 >>NP_001278646 (OMIM: 606021) melanoma antigen preferent (493 aa) initn: 3290 init1: 3290 opt: 3290 Z-score: 3673.9 bits: 689.3 E(85289): 6.7e-198 Smith-Waterman score: 3290; 100.0% identity (100.0% similar) in 493 aa overlap (17-509:1-493) 10 20 30 40 50 60 pF1KB8 MERRRLRGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA :::::::::::::::::::::::::::::::::::::::::::: NP_001 MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 10 20 30 40 70 80 90 100 110 120 pF1KB8 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB8 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB8 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 410 420 430 440 450 460 490 500 pF1KB8 WLSANPCPHCGDRTFYDPEPILCPCFMPN ::::::::::::::::::::::::::::: NP_001 WLSANPCPHCGDRTFYDPEPILCPCFMPN 470 480 490 >>NP_001305055 (OMIM: 606021) melanoma antigen preferent (493 aa) initn: 3290 init1: 3290 opt: 3290 Z-score: 3673.9 bits: 689.3 E(85289): 6.7e-198 Smith-Waterman score: 3290; 100.0% identity (100.0% similar) in 493 aa overlap (17-509:1-493) 10 20 30 40 50 60 pF1KB8 MERRRLRGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA :::::::::::::::::::::::::::::::::::::::::::: NP_001 MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 10 20 30 40 70 80 90 100 110 120 pF1KB8 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB8 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB8 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 410 420 430 440 450 460 490 500 pF1KB8 WLSANPCPHCGDRTFYDPEPILCPCFMPN ::::::::::::::::::::::::::::: NP_001 WLSANPCPHCGDRTFYDPEPILCPCFMPN 470 480 490 >>NP_001278648 (OMIM: 606021) melanoma antigen preferent (493 aa) initn: 3290 init1: 3290 opt: 3290 Z-score: 3673.9 bits: 689.3 E(85289): 6.7e-198 Smith-Waterman score: 3290; 100.0% identity (100.0% similar) in 493 aa overlap (17-509:1-493) 10 20 30 40 50 60 pF1KB8 MERRRLRGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA :::::::::::::::::::::::::::::::::::::::::::: NP_001 MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 10 20 30 40 70 80 90 100 110 120 pF1KB8 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB8 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB8 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 410 420 430 440 450 460 490 500 pF1KB8 WLSANPCPHCGDRTFYDPEPILCPCFMPN ::::::::::::::::::::::::::::: NP_001 WLSANPCPHCGDRTFYDPEPILCPCFMPN 470 480 490 509 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:56:04 2016 done: Fri Nov 4 14:56:05 2016 Total Scan time: 10.200 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]