FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8728, 372 aa 1>>>pF1KB8728 372 - 372 aa - 372 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7444+/-0.000826; mu= 14.8727+/- 0.050 mean_var=73.1048+/-14.373, 0's: 0 Z-trim(108.0): 87 B-trim: 3 in 1/50 Lambda= 0.150003 statistics sampled from 9844 (9935) to 9844 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.305), width: 16 Scan time: 2.820 The best scores are: opt bits E(32554) CCDS13752.1 USP18 gene_id:11274|Hs108|chr22 ( 372) 2555 562.0 3e-160 CCDS41619.1 USP47 gene_id:55031|Hs108|chr11 (1287) 412 98.5 3.6e-20 CCDS60725.1 USP47 gene_id:55031|Hs108|chr11 (1355) 412 98.5 3.8e-20 CCDS81554.1 USP47 gene_id:55031|Hs108|chr11 (1375) 412 98.5 3.8e-20 CCDS44084.1 USP48 gene_id:84196|Hs108|chr1 ( 485) 359 86.8 4.4e-17 CCDS81277.1 USP48 gene_id:84196|Hs108|chr1 ( 983) 359 86.9 8.1e-17 CCDS30623.1 USP48 gene_id:84196|Hs108|chr1 (1035) 359 86.9 8.4e-17 CCDS46547.1 USP40 gene_id:55230|Hs108|chr2 (1247) 299 74.0 8e-13 CCDS43892.1 USP20 gene_id:10868|Hs108|chr9 ( 914) 286 71.1 4.3e-12 CCDS14370.1 USP51 gene_id:158880|Hs108|chrX ( 711) 273 68.3 2.4e-11 CCDS680.1 USP33 gene_id:23032|Hs108|chr1 ( 828) 266 66.8 8e-11 CCDS65260.1 USP27X gene_id:389856|Hs108|chrX ( 438) 262 65.8 8.4e-11 CCDS679.1 USP33 gene_id:23032|Hs108|chr1 ( 911) 266 66.8 8.6e-11 CCDS44154.2 USP24 gene_id:23358|Hs108|chr1 (2620) 272 68.3 8.7e-11 CCDS678.1 USP33 gene_id:23032|Hs108|chr1 ( 942) 266 66.8 8.9e-11 >>CCDS13752.1 USP18 gene_id:11274|Hs108|chr22 (372 aa) initn: 2555 init1: 2555 opt: 2555 Z-score: 2990.4 bits: 562.0 E(32554): 3e-160 Smith-Waterman score: 2555; 100.0% identity (100.0% similar) in 372 aa overlap (1-372:1-372) 10 20 30 40 50 60 pF1KB8 MSKAFGLLRQICQSILAESSQSPADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MSKAFGLLRQICQSILAESSQSPADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 GQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYTIRVKDSLICVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYTIRVKDSLICVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 CAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 CAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 QVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 QVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 QYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQE 310 320 330 340 350 360 370 pF1KB8 TAYLLVYMKMEC :::::::::::: CCDS13 TAYLLVYMKMEC 370 >>CCDS41619.1 USP47 gene_id:55031|Hs108|chr11 (1287 aa) initn: 547 init1: 228 opt: 412 Z-score: 475.6 bits: 98.5 E(32554): 3.6e-20 Smith-Waterman score: 479; 27.0% identity (57.7% similar) in 352 aa overlap (53-352:98-449) 30 40 50 60 70 80 pF1KB8 PADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFTRI : ::: : ..:: ::::.:.. :. .: CCDS41 PLPREGSGGSTSDYVSQSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNA 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB8 LKRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQ : . .. .. :.:.:. :. .: :...:.. ... . . . :::. . CCDS41 LYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQE 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB8 LYLKLWNLIKDQITDVHLVERLQALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDV- : ... .... ... .. .. :: ..:: . :..:..:. : ...: .:: . CCDS41 LCRVMFDALEQKWKQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYG 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB8 DSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSI .:. . ..:.::: :.::. :.. .. ::: : :: ... :.. :.: ::..: ::.. CCDS41 SSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDF 250 260 270 280 290 300 270 280 290 pF1KB8 RNSQTRKI--CHSLYFPQSLDFSQILPM------KRESC-DA------------------ . ..: . ::. ::.: .. . . ::: :. CCDS41 DYTTMHRIKLNDRMTFPEELDMSTFIDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFS 310 320 330 340 350 360 300 310 320 330 pF1KB8 -----------EEQSGGQ-------------YELFAVIAHVGMADSGHYCVYIRNAVDGK : .:: . ::::.:..: : : .::: . :.. : . CCDS41 NDDGVDEGICLETNSGTEKISKSGLEKNSLIYELFSVMVHSGSAAGGHYYACIKSFSDEQ 370 380 390 400 410 420 340 350 360 370 pF1KB8 WFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMKMEC :. :::... .. :::. :.: CCDS41 WYSFNDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASSTNAYMLIYRLKDPARNAKFLEV 430 440 450 460 470 480 >>CCDS60725.1 USP47 gene_id:55031|Hs108|chr11 (1355 aa) initn: 547 init1: 228 opt: 412 Z-score: 475.3 bits: 98.5 E(32554): 3.8e-20 Smith-Waterman score: 479; 27.0% identity (57.7% similar) in 352 aa overlap (53-352:166-517) 30 40 50 60 70 80 pF1KB8 PADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFTRI : ::: : ..:: ::::.:.. :. .: CCDS60 PLPREGSGGSTSDYVSQSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNA 140 150 160 170 180 190 90 100 110 120 130 140 pF1KB8 LKRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQ : . .. .. :.:.:. :. .: :...:.. ... . . . :::. . CCDS60 LYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQE 200 210 220 230 240 250 150 160 170 180 190 200 pF1KB8 LYLKLWNLIKDQITDVHLVERLQALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDV- : ... .... ... .. .. :: ..:: . :..:..:. : ...: .:: . CCDS60 LCRVMFDALEQKWKQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYG 260 270 280 290 300 310 210 220 230 240 250 260 pF1KB8 DSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSI .:. . ..:.::: :.::. :.. .. ::: : :: ... :.. :.: ::..: ::.. CCDS60 SSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDF 320 330 340 350 360 370 270 280 290 pF1KB8 RNSQTRKI--CHSLYFPQSLDFSQILPM------KRESC-DA------------------ . ..: . ::. ::.: .. . . ::: :. CCDS60 DYTTMHRIKLNDRMTFPEELDMSTFIDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFS 380 390 400 410 420 430 300 310 320 330 pF1KB8 -----------EEQSGGQ-------------YELFAVIAHVGMADSGHYCVYIRNAVDGK : .:: . ::::.:..: : : .::: . :.. : . CCDS60 NDDGVDEGICLETNSGTEKISKSGLEKNSLIYELFSVMVHSGSAAGGHYYACIKSFSDEQ 440 450 460 470 480 490 340 350 360 370 pF1KB8 WFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMKMEC :. :::... .. :::. :.: CCDS60 WYSFNDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASSTNAYMLIYRLKDPARNAKFLEV 500 510 520 530 540 550 >>CCDS81554.1 USP47 gene_id:55031|Hs108|chr11 (1375 aa) initn: 547 init1: 228 opt: 412 Z-score: 475.2 bits: 98.5 E(32554): 3.8e-20 Smith-Waterman score: 479; 27.0% identity (57.7% similar) in 352 aa overlap (53-352:186-537) 30 40 50 60 70 80 pF1KB8 PADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFTRI : ::: : ..:: ::::.:.. :. .: CCDS81 PLPREGSGGSTSDYVSQSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNA 160 170 180 190 200 210 90 100 110 120 130 140 pF1KB8 LKRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQ : . .. .. :.:.:. :. .: :...:.. ... . . . :::. . CCDS81 LYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQE 220 230 240 250 260 270 150 160 170 180 190 200 pF1KB8 LYLKLWNLIKDQITDVHLVERLQALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDV- : ... .... ... .. .. :: ..:: . :..:..:. : ...: .:: . CCDS81 LCRVMFDALEQKWKQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYG 280 290 300 310 320 330 210 220 230 240 250 260 pF1KB8 DSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSI .:. . ..:.::: :.::. :.. .. ::: : :: ... :.. :.: ::..: ::.. CCDS81 SSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDF 340 350 360 370 380 390 270 280 290 pF1KB8 RNSQTRKI--CHSLYFPQSLDFSQILPM------KRESC-DA------------------ . ..: . ::. ::.: .. . . ::: :. CCDS81 DYTTMHRIKLNDRMTFPEELDMSTFIDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFS 400 410 420 430 440 450 300 310 320 330 pF1KB8 -----------EEQSGGQ-------------YELFAVIAHVGMADSGHYCVYIRNAVDGK : .:: . ::::.:..: : : .::: . :.. : . CCDS81 NDDGVDEGICLETNSGTEKISKSGLEKNSLIYELFSVMVHSGSAAGGHYYACIKSFSDEQ 460 470 480 490 500 510 340 350 360 370 pF1KB8 WFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMKMEC :. :::... .. :::. :.: CCDS81 WYSFNDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASSTNAYMLIYRLKDPARNAKFLEV 520 530 540 550 560 570 >>CCDS44084.1 USP48 gene_id:84196|Hs108|chr1 (485 aa) initn: 287 init1: 135 opt: 359 Z-score: 420.2 bits: 86.8 E(32554): 4.4e-17 Smith-Waterman score: 359; 27.0% identity (56.7% similar) in 307 aa overlap (52-339:86-374) 30 40 50 60 70 80 pF1KB8 SPADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFTR ...::: :.: :: .:...::. .:... . CCDS44 VGIGEHIWLGEIDENSFHNIDDPNCERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQ 60 70 80 90 100 110 90 100 110 120 130 pF1KB8 IL-------KRITVPRGADEQRRSVP----FQMLLLLEKMQDSRQKAVRPLELAYCLQKC : . . : .:.. : .. :. .:.: .. . : .. : CCDS44 ALYLCPSTCSDYMLGDGIQEEKDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKAL--- 120 130 140 150 160 170 140 150 160 170 180 pF1KB8 NVPLFVQHDAAQLYLKLWNLIKDQIT-----DVHLVERLQALYTIRVKDSLICVDCAMES .. :.:: .. . .:..: .. ::. . .: . . .: .:. :: CCDS44 GLDTGQQQDAQEFSKLFMSLLEDTLSKQKNPDVRNI--VQQQFCGEYAYVTVCNQCGRES 180 190 200 210 220 230 190 200 210 220 230 240 pF1KB8 SRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKL . :.. : :.. . : : : . :.. ..: . .. ::::: .: . . ..: CCDS44 KLLSKFYELELNI-----QGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRL 240 250 260 270 280 250 260 270 280 290 300 pF1KB8 THLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQY--E :: ::...:::: . :. :. . . ::.:: :. :..::.: : CCDS44 LSLPCTLNLQLMRFVF----DRQTGHKKKLNTYIGFSEILDME----PYVEHKGGSYVYE 290 300 310 320 330 310 320 330 340 350 360 pF1KB8 LFAVIAHVGM-ADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETA : ::. : :. : :::: ..... .:.:. ::: .: CCDS44 LSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQLGIEEDLAEPSKSQ 340 350 360 370 380 390 370 pF1KB8 YLLVYMKMEC CCDS44 TRKPKCGKGTHCSRNAYMLVYRLQTQEKPNTTVQVPAFLQELVDRDNSKFEEWCIEMAEM 400 410 420 430 440 450 >>CCDS81277.1 USP48 gene_id:84196|Hs108|chr1 (983 aa) initn: 287 init1: 135 opt: 359 Z-score: 415.4 bits: 86.9 E(32554): 8.1e-17 Smith-Waterman score: 359; 27.0% identity (56.7% similar) in 307 aa overlap (52-339:86-374) 30 40 50 60 70 80 pF1KB8 SPADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFTR ...::: :.: :: .:...::. .:... . CCDS81 VGIGEHIWLGEIDENSFHNIDDPNCERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQ 60 70 80 90 100 110 90 100 110 120 130 pF1KB8 IL-------KRITVPRGADEQRRSVP----FQMLLLLEKMQDSRQKAVRPLELAYCLQKC : . . : .:.. : .. :. .:.: .. . : .. : CCDS81 ALYLCPSTCSDYMLGDGIQEEKDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKAL--- 120 130 140 150 160 170 140 150 160 170 180 pF1KB8 NVPLFVQHDAAQLYLKLWNLIKDQIT-----DVHLVERLQALYTIRVKDSLICVDCAMES .. :.:: .. . .:..: .. ::. . .: . . .: .:. :: CCDS81 GLDTGQQQDAQEFSKLFMSLLEDTLSKQKNPDVRNI--VQQQFCGEYAYVTVCNQCGRES 180 190 200 210 220 230 190 200 210 220 230 240 pF1KB8 SRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKL . :.. : :.. . : : : . :.. ..: . .. ::::: .: . . ..: CCDS81 KLLSKFYELELNI-----QGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRL 240 250 260 270 280 250 260 270 280 290 300 pF1KB8 THLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQY--E :: ::...:::: . :. :. . . ::.:: :. :..::.: : CCDS81 LSLPCTLNLQLMRFVF----DRQTGHKKKLNTYIGFSEILDME----PYVEHKGGSYVYE 290 300 310 320 330 310 320 330 340 350 360 pF1KB8 LFAVIAHVGM-ADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETA : ::. : :. : :::: ..... .:.:. ::: .: CCDS81 LSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQLGIEEDLAEPSKSQ 340 350 360 370 380 390 370 pF1KB8 YLLVYMKMEC CCDS81 TRKPKCGKGTHCSRNAYMLVYRLQTQEKPNTTVQVPAFLQELVDRDNSKFEEWCIEMAEM 400 410 420 430 440 450 >>CCDS30623.1 USP48 gene_id:84196|Hs108|chr1 (1035 aa) initn: 287 init1: 135 opt: 359 Z-score: 415.1 bits: 86.9 E(32554): 8.4e-17 Smith-Waterman score: 359; 27.0% identity (56.7% similar) in 307 aa overlap (52-339:86-374) 30 40 50 60 70 80 pF1KB8 SPADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFTR ...::: :.: :: .:...::. .:... . CCDS30 VGIGEHIWLGEIDENSFHNIDDPNCERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQ 60 70 80 90 100 110 90 100 110 120 130 pF1KB8 IL-------KRITVPRGADEQRRSVP----FQMLLLLEKMQDSRQKAVRPLELAYCLQKC : . . : .:.. : .. :. .:.: .. . : .. : CCDS30 ALYLCPSTCSDYMLGDGIQEEKDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKAL--- 120 130 140 150 160 170 140 150 160 170 180 pF1KB8 NVPLFVQHDAAQLYLKLWNLIKDQIT-----DVHLVERLQALYTIRVKDSLICVDCAMES .. :.:: .. . .:..: .. ::. . .: . . .: .:. :: CCDS30 GLDTGQQQDAQEFSKLFMSLLEDTLSKQKNPDVRNI--VQQQFCGEYAYVTVCNQCGRES 180 190 200 210 220 230 190 200 210 220 230 240 pF1KB8 SRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKL . :.. : :.. . : : : . :.. ..: . .. ::::: .: . . ..: CCDS30 KLLSKFYELELNI-----QGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRL 240 250 260 270 280 250 260 270 280 290 300 pF1KB8 THLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQY--E :: ::...:::: . :. :. . . ::.:: :. :..::.: : CCDS30 LSLPCTLNLQLMRFVF----DRQTGHKKKLNTYIGFSEILDME----PYVEHKGGSYVYE 290 300 310 320 330 310 320 330 340 350 360 pF1KB8 LFAVIAHVGM-ADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETA : ::. : :. : :::: ..... .:.:. ::: .: CCDS30 LSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQLGIEEDLAEPSKSQ 340 350 360 370 380 390 370 pF1KB8 YLLVYMKMEC CCDS30 TRKPKCGKGTHCSRNAYMLVYRLQTQEKPNTTVQVPAFLQELVDRDNSKFEEWCIEMAEM 400 410 420 430 440 450 >>CCDS46547.1 USP40 gene_id:55230|Hs108|chr2 (1247 aa) initn: 193 init1: 77 opt: 299 Z-score: 343.7 bits: 74.0 E(32554): 8e-13 Smith-Waterman score: 299; 25.1% identity (55.6% similar) in 338 aa overlap (29-348:34-348) 10 20 30 40 50 pF1KB8 MSKAFGLLRQICQSILAESSQSPADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLH :: . . .. ::: .: :.. CCDS46 FLRVVFSFTMFGDLFEEEYSTVSNNQYGKGKKLKTKALEPPAPREFT-------NLSGIR 10 20 30 40 50 60 70 80 90 100 pF1KB8 NIGQTCCLNSLIQVFVMNVDFTRILKRITVPR--G-------ADEQRRSVPFQMLLLLEK : : :: ::::.:.. .. .: . : . :. : : . : .:.:. :. . CCDS46 NQGGTCYLNSLLQTLHFTPEFREALFSLG-PEELGLFEDKDKPDAKVRIIPLQLQRLFAQ 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 MQDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYT . :.:. .:. . . . :::. .: :.. .. ... . . . :: CCDS46 LLLLDQEAASTADLTDSFGWTSNEEMRQHDVQELNRILFSALETSLVGTSGHDLIYRLYH 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 IRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCF . ....: .: : :. ..: : ... .:.. ::::: .. .:. . .. . CCDS46 GTIVNQIVCKECKNVSERQEDFLDLTVAVKNVSG-----LEDALWNMYVEEEVFDCDNLY 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB8 -CENCGKKTRGKQVLKLTHLPQTLTIHLMRFS---IRNSQTRKI-CHSLYFPQSLDFSQI : .: . ... . :: .:: ::. :.::. .. . .. :.. :: .... CCDS46 HCGTCDRLVKAAKSAKLRKLPPFLTVSLLRFNFDFVKCERYKETSCYT--FPLRINLK-- 240 250 260 270 280 290 300 310 320 330 340 pF1KB8 LPMKRESCDAEEQSGGQY--ELFAVIAHVGMADSGHYCVYIRNAVD--GKWFCFNDSNIC :. :. : . .: .::.:: : : .::: :::.. :: :.: .... CCDS46 -PF----CEQSELDDLEYIYDLFSVIIHKGGCYGGHYHVYIKD-VDHLGNWQFQEEKSKP 290 300 310 320 330 340 350 360 370 pF1KB8 LVSWEDIQCTYGNPNYHWQETAYLLVYMKMEC :. .:.: CCDS46 DVNLKDLQSEEEIDHPLMILKAILLEENNLIPVDQLGQKLLKKIGISWNKKYRKQHGPLR 350 360 370 380 390 400 >>CCDS43892.1 USP20 gene_id:10868|Hs108|chr9 (914 aa) initn: 261 init1: 153 opt: 286 Z-score: 330.6 bits: 71.1 E(32554): 4.3e-12 Smith-Waterman score: 286; 34.9% identity (57.7% similar) in 149 aa overlap (205-352:535-677) 180 190 200 210 220 230 pF1KB8 SLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCG :. :::: : :: ::.. . :: : CCDS43 DSYAAQGWLAFIVEYIRRFVVSCTPSWFWGPVVTLEDCLAAFFAADELKGDNMYSCERCK 510 520 530 540 550 560 240 250 260 270 280 290 pF1KB8 KKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFP-QSLDFSQILPMKRESCD : : . :. .::. : ::: :: . . :: . :: ..::. :. . : CCDS43 KLRNGVKYCKVLRLPEILCIHLKRFRHEVMYSFKINSHVSFPLEGLDLR---PFLAKECT 570 580 590 600 610 620 300 310 320 330 340 350 pF1KB8 AEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGN .. . :.:..:: : : : :::: .: .:...:.:. :.:. . : .: . : CCDS43 SQITT---YDLLSVICHHGTAGSGHYIAYCQNVINGQWYEFDDQYVTEVHETVVQNAEGY 630 640 650 660 670 360 370 pF1KB8 PNYHWQETAYLLVYMKMEC CCDS43 VLFYRKSSEEAMRERQQVVSLAAMREPSLLRFYVSREWLNKFNTFAEPGPITNQTFLCSH 680 690 700 710 720 730 >>CCDS14370.1 USP51 gene_id:158880|Hs108|chrX (711 aa) initn: 283 init1: 103 opt: 273 Z-score: 317.0 bits: 68.3 E(32554): 2.4e-11 Smith-Waterman score: 309; 23.8% identity (51.6% similar) in 382 aa overlap (13-352:322-698) 10 20 30 40 pF1KB8 MSKAFGLLRQICQSILAESSQSPADLEEKKEEDSNMKREQPR :.... . .. . : ::.. .. . . . CCDS14 VYDKDIEQIAKETKEKILRLLTSTSTDVSHQQFMTSGFEDKQSTCETKEQEPKLVKPKKK 300 310 320 330 340 350 50 60 70 80 90 pF1KB8 ERPRAWDYPHGLVGLHNIGQTCCLNSLIQVFV---MNVDFTRILKRITVPRGADEQRRSV .: .. : :: :: :.:.:: .: ..:... . :: :. . . CCDS14 RRKKSV-YTVGLRGLINLGNTCFMNCIVQALTHIPLLKDFFLSDKHKCI---MTSPSLCL 360 370 380 390 400 100 110 120 130 140 150 pF1KB8 PFQMLLLLEKMQDSRQKAVRPLELAYCL--QKCNVPLFVQHDAAQLYLKLWNLIKDQITD .: :.. : .. . : .: . . . .. . :.:: .. . . .... . : CCDS14 VCEMSSLFHAMYSGSRTPHIPYKLLHLIWIHAEHLAGYRQQDAHEFLIAILDVLHRHSKD 410 420 430 440 450 460 160 170 180 190 200 pF1KB8 VHLVER----------LQALYTIRVKDSLICVDCAMESSRNSSM----LTLPLSLFDVDS .. .. ..: ..... : : :. . : :: : :: CCDS14 DSGGQEANNPNCCNCIIDQIFTGGLQSDVTCQACHSVSTTIDPCWDISLDLPGSCATFDS 470 480 490 500 510 520 210 220 230 240 pF1KB8 K-P---------------LKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTH . : . .: : :. : .:..:.:..: :..: . .. . : . . CCDS14 QNPERADSTVSRDDHIPGIPSLTDCLQWFTRPEHLGSSAKIKCNSCQSYQESTKQLTMKK 530 540 550 560 570 580 250 260 270 280 290 300 pF1KB8 LPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRESCDAEEQ-------SGG :: . .:: :: ..: ::: . :: ::.. .: .:: : : . . CCDS14 LPIVACFHLKRFEHVGKQRRKINTFISFPLELDMTPFLASTKESRMKEGQPPTDCVPNEN 590 600 610 620 630 640 310 320 330 340 350 360 pF1KB8 QYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQE .: ::::: : : .:::: .::. : .:: .:. : .. ::. . : CCDS14 KYSLFAVINHHGTLESGHYTSFIRQQKD-QWFSCDDAIITKATIEDLLYSEGYLLFYHKQ 650 660 670 680 690 700 370 pF1KB8 TAYLLVYMKMEC CCDS14 GLEKD 710 372 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:59:36 2016 done: Fri Nov 4 14:59:36 2016 Total Scan time: 2.820 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]