FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8738, 111 aa 1>>>pF1KB8738 111 - 111 aa - 111 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6431+/-0.000257; mu= 14.7497+/- 0.016 mean_var=62.1757+/-12.367, 0's: 0 Z-trim(121.2): 17 B-trim: 0 in 0/55 Lambda= 0.162654 statistics sampled from 37544 (37562) to 37544 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.813), E-opt: 0.2 (0.44), width: 16 Scan time: 4.660 The best scores are: opt bits E(85289) NP_055195 (OMIM: 300361) protein BEX3 isoform b [H ( 111) 798 194.3 3.5e-50 NP_996798 (OMIM: 300361) protein BEX3 isoform b [H ( 111) 798 194.3 3.5e-50 NP_001269603 (OMIM: 300361) protein BEX3 isoform c ( 191) 798 194.5 5.2e-50 NP_996800 (OMIM: 300361) protein BEX3 isoform a [H ( 101) 732 178.7 1.5e-45 NP_001153032 (OMIM: 300693) protein BEX5 [Homo sap ( 111) 406 102.3 1.7e-22 NP_001012996 (OMIM: 300693) protein BEX5 [Homo sap ( 111) 406 102.3 1.7e-22 NP_001121160 (OMIM: 300692) protein BEX4 [Homo sap ( 120) 371 94.1 5.4e-20 NP_001073894 (OMIM: 300692) protein BEX4 [Homo sap ( 120) 371 94.1 5.4e-20 NP_060946 (OMIM: 300690) protein BEX1 [Homo sapien ( 125) 263 68.8 2.4e-12 NP_001161873 (OMIM: 300691) protein BEX2 isoform 3 ( 128) 234 62.0 2.7e-10 NP_116010 (OMIM: 300691) protein BEX2 isoform 3 [H ( 128) 234 62.0 2.7e-10 NP_001161872 (OMIM: 300691) protein BEX2 isoform 2 ( 159) 234 62.0 3.2e-10 NP_001161871 (OMIM: 300691) protein BEX2 isoform 1 ( 160) 234 62.1 3.2e-10 NP_689491 (OMIM: 300771) transcription elongation ( 100) 136 38.9 0.0019 XP_016885144 (OMIM: 300771) PREDICTED: transcripti ( 100) 136 38.9 0.0019 >>NP_055195 (OMIM: 300361) protein BEX3 isoform b [Homo (111 aa) initn: 798 init1: 798 opt: 798 Z-score: 1022.0 bits: 194.3 E(85289): 3.5e-50 Smith-Waterman score: 798; 100.0% identity (100.0% similar) in 111 aa overlap (1-111:1-111) 10 20 30 40 50 60 pF1KB8 MANIHQENEEMEQPMQNGEEDRPLGGGEGHQPAGNRRGQARRLAPNFRWAIPNRQINDGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MANIHQENEEMEQPMQNGEEDRPLGGGEGHQPAGNRRGQARRLAPNFRWAIPNRQINDGM 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 GGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP 70 80 90 100 110 >>NP_996798 (OMIM: 300361) protein BEX3 isoform b [Homo (111 aa) initn: 798 init1: 798 opt: 798 Z-score: 1022.0 bits: 194.3 E(85289): 3.5e-50 Smith-Waterman score: 798; 100.0% identity (100.0% similar) in 111 aa overlap (1-111:1-111) 10 20 30 40 50 60 pF1KB8 MANIHQENEEMEQPMQNGEEDRPLGGGEGHQPAGNRRGQARRLAPNFRWAIPNRQINDGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 MANIHQENEEMEQPMQNGEEDRPLGGGEGHQPAGNRRGQARRLAPNFRWAIPNRQINDGM 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 GGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 GGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP 70 80 90 100 110 >>NP_001269603 (OMIM: 300361) protein BEX3 isoform c [Ho (191 aa) initn: 798 init1: 798 opt: 798 Z-score: 1018.8 bits: 194.5 E(85289): 5.2e-50 Smith-Waterman score: 798; 100.0% identity (100.0% similar) in 111 aa overlap (1-111:81-191) 10 20 30 pF1KB8 MANIHQENEEMEQPMQNGEEDRPLGGGEGH :::::::::::::::::::::::::::::: NP_001 PAPRCPELGGLAFGPGKSGAEKQPEKKNLIMANIHQENEEMEQPMQNGEEDRPLGGGEGH 60 70 80 90 100 110 40 50 60 70 80 90 pF1KB8 QPAGNRRGQARRLAPNFRWAIPNRQINDGMGGDGDDMEIFMEEMREIRRKLRELQLRNCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPAGNRRGQARRLAPNFRWAIPNRQINDGMGGDGDDMEIFMEEMREIRRKLRELQLRNCL 120 130 140 150 160 170 100 110 pF1KB8 RILMGELSNHHDHHDEFCLMP ::::::::::::::::::::: NP_001 RILMGELSNHHDHHDEFCLMP 180 190 >>NP_996800 (OMIM: 300361) protein BEX3 isoform a [Homo (101 aa) initn: 732 init1: 732 opt: 732 Z-score: 938.8 bits: 178.7 E(85289): 1.5e-45 Smith-Waterman score: 732; 100.0% identity (100.0% similar) in 101 aa overlap (11-111:1-101) 10 20 30 40 50 60 pF1KB8 MANIHQENEEMEQPMQNGEEDRPLGGGEGHQPAGNRRGQARRLAPNFRWAIPNRQINDGM :::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 MEQPMQNGEEDRPLGGGEGHQPAGNRRGQARRLAPNFRWAIPNRQINDGM 10 20 30 40 50 70 80 90 100 110 pF1KB8 GGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 GGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP 60 70 80 90 100 >>NP_001153032 (OMIM: 300693) protein BEX5 [Homo sapiens (111 aa) initn: 393 init1: 188 opt: 406 Z-score: 524.8 bits: 102.3 E(85289): 1.7e-22 Smith-Waterman score: 406; 57.0% identity (73.7% similar) in 114 aa overlap (1-111:1-111) 10 20 30 40 50 pF1KB8 MANIHQENEEMEQ-PMQNGEEDRPLGGGEGHQPAGNRRGQARRLAPNFRWAIPNRQIN-- : :. .::. .:. :.:: : ::::: ..:.:: .: ::.: .::: .. NP_001 MENVPKENKVVEKAPVQN--EAPALGGGEYQEPGGNVKGVWAPPAPGFGEDVPNRLVDNI 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 DGMGGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP : . ::::::: :::::::.:::.:::::: ::::.:. :::::::::::: NP_001 DMIDGDGDDMERFMEEMRELRRKIRELQLRYSLRILIGD-PPHHDHHDEFCLMP 60 70 80 90 100 110 >>NP_001012996 (OMIM: 300693) protein BEX5 [Homo sapiens (111 aa) initn: 393 init1: 188 opt: 406 Z-score: 524.8 bits: 102.3 E(85289): 1.7e-22 Smith-Waterman score: 406; 57.0% identity (73.7% similar) in 114 aa overlap (1-111:1-111) 10 20 30 40 50 pF1KB8 MANIHQENEEMEQ-PMQNGEEDRPLGGGEGHQPAGNRRGQARRLAPNFRWAIPNRQIN-- : :. .::. .:. :.:: : ::::: ..:.:: .: ::.: .::: .. NP_001 MENVPKENKVVEKAPVQN--EAPALGGGEYQEPGGNVKGVWAPPAPGFGEDVPNRLVDNI 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 DGMGGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP : . ::::::: :::::::.:::.:::::: ::::.:. :::::::::::: NP_001 DMIDGDGDDMERFMEEMRELRRKIRELQLRYSLRILIGD-PPHHDHHDEFCLMP 60 70 80 90 100 110 >>NP_001121160 (OMIM: 300692) protein BEX4 [Homo sapiens (120 aa) initn: 394 init1: 131 opt: 371 Z-score: 480.0 bits: 94.1 E(85289): 5.4e-20 Smith-Waterman score: 371; 55.0% identity (75.7% similar) in 111 aa overlap (3-111:16-120) 10 20 30 40 pF1KB8 MANIHQENEEMEQ-PMQNGEEDRPLGGGEGHQPAGN-RRGQARRLAP : .:::: :: : :: ::.: ::::::..:.:: :::..:::.: NP_001 MESKEELAANNLNGENAQQENEGGEQAPTQNEEESRHLGGGEGQKPGGNIRRGRVRRLVP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 NFRWAIPNRQINDGMGGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHD :::::::::.:. . . : :.: :. .: ::.:: :: :.:. .:. : .::.: NP_001 NFRWAIPNRHIEHNEARD--DVERFVGQMMEIKRKTREQQMRHYMRFQTPEPDNHYD--- 70 80 90 100 110 110 pF1KB8 EFCLMP :::.: NP_001 -FCLIP 120 >>NP_001073894 (OMIM: 300692) protein BEX4 [Homo sapiens (120 aa) initn: 394 init1: 131 opt: 371 Z-score: 480.0 bits: 94.1 E(85289): 5.4e-20 Smith-Waterman score: 371; 55.0% identity (75.7% similar) in 111 aa overlap (3-111:16-120) 10 20 30 40 pF1KB8 MANIHQENEEMEQ-PMQNGEEDRPLGGGEGHQPAGN-RRGQARRLAP : .:::: :: : :: ::.: ::::::..:.:: :::..:::.: NP_001 MESKEELAANNLNGENAQQENEGGEQAPTQNEEESRHLGGGEGQKPGGNIRRGRVRRLVP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 NFRWAIPNRQINDGMGGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHD :::::::::.:. . . : :.: :. .: ::.:: :: :.:. .:. : .::.: NP_001 NFRWAIPNRHIEHNEARD--DVERFVGQMMEIKRKTREQQMRHYMRFQTPEPDNHYD--- 70 80 90 100 110 110 pF1KB8 EFCLMP :::.: NP_001 -FCLIP 120 >>NP_060946 (OMIM: 300690) protein BEX1 [Homo sapiens] (125 aa) initn: 239 init1: 105 opt: 263 Z-score: 342.8 bits: 68.8 E(85289): 2.4e-12 Smith-Waterman score: 263; 43.4% identity (62.8% similar) in 113 aa overlap (1-111:14-125) 10 20 30 40 pF1KB8 MANIHQENEEMEQPMQNGEE-DRPLGGGEGHQPAGNRRG-QARRLAP : : .::::: :: ..:: :: .:: : :::: ..:. NP_060 MESKEKRAVNSLSMENANQENEEKEQVANKGEPLALPLDAGEYCVPRGNRRRFRVRQPIL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 NFRWAIPNRQINDGMGGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHD ..:: . .: . ..:: . ::.:.. .:::: :: . :: . . :::::: NP_060 QYRWDMMHRLGEPQARMREENMERIGEEVRQLMEKLREKQLSHSLRAVSTD-PPHHDHHD 70 80 90 100 110 110 pF1KB8 EFCLMP :::::: NP_060 EFCLMP 120 >>NP_001161873 (OMIM: 300691) protein BEX2 isoform 3 [Ho (128 aa) initn: 190 init1: 105 opt: 234 Z-score: 305.9 bits: 62.0 E(85289): 2.7e-10 Smith-Waterman score: 234; 41.2% identity (62.3% similar) in 114 aa overlap (3-111:16-128) 10 20 30 40 pF1KB8 MANIHQENEEM---EQPMQNGEE-DRPLGGGEGHQPAGNRRG-QARR :..:::.: :: ..:: ::. .: : :::: ..:. NP_001 MESKEERALNNLIVENVNQENDEKDEKEQVANKGEPLALPLNVSEYCVPRGNRRRFRVRQ 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 LAPNFRWAIPNRQINDGMGGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHD ..:: : .: . ..:: . ::.:.. .:::: :: . :: . . ::: NP_001 PILQYRWDIMHRLGEPQARMREENMERIGEEVRQLMEKLREKQLSHSLRAVSTD-PPHHD 70 80 90 100 110 110 pF1KB8 HHDEFCLMP ::::::::: NP_001 HHDEFCLMP 120 111 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:06:11 2016 done: Fri Nov 4 15:06:12 2016 Total Scan time: 4.660 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]