FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8740, 183 aa 1>>>pF1KB8740 183 - 183 aa - 183 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8109+/-0.000247; mu= 16.6466+/- 0.016 mean_var=67.7915+/-13.702, 0's: 0 Z-trim(121.5): 8 B-trim: 59 in 1/56 Lambda= 0.155771 statistics sampled from 38304 (38314) to 38304 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.8), E-opt: 0.2 (0.449), width: 16 Scan time: 5.210 The best scores are: opt bits E(85289) NP_001092260 (OMIM: 300961) mid1-interacting prote ( 183) 1267 292.4 2.8e-79 NP_001092261 (OMIM: 300961) mid1-interacting prote ( 183) 1267 292.4 2.8e-79 NP_067065 (OMIM: 300961) mid1-interacting protein ( 183) 1267 292.4 2.8e-79 NP_003242 (OMIM: 601926) thyroid hormone-inducible ( 146) 152 41.7 0.00063 >>NP_001092260 (OMIM: 300961) mid1-interacting protein 1 (183 aa) initn: 1267 init1: 1267 opt: 1267 Z-score: 1544.4 bits: 292.4 E(85289): 2.8e-79 Smith-Waterman score: 1267; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183) 10 20 30 40 50 60 pF1KB8 MMQICDTYNQKHSLFNAMNRFIGAVNNMDQTVMVPSLLRDVPLADPGLDNDVGVEVGGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMQICDTYNQKHSLFNAMNRFIGAVNNMDQTVMVPSLLRDVPLADPGLDNDVGVEVGGSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GCLEERTPPVPDSGSANGSFFAPSRDMYSHYVLLKSIRNDIEWGVLHQPPPPAGSEEGSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GCLEERTPPVPDSGSANGSFFAPSRDMYSHYVLLKSIRNDIEWGVLHQPPPPAGSEEGSA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 WKSKDILVDLGHLEGADAGEEDLEQQFHYHLRGLHTVLSKLTRKANILTNRYKQEIGFGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WKSKDILVDLGHLEGADAGEEDLEQQFHYHLRGLHTVLSKLTRKANILTNRYKQEIGFGN 130 140 150 160 170 180 pF1KB8 WGH ::: NP_001 WGH >>NP_001092261 (OMIM: 300961) mid1-interacting protein 1 (183 aa) initn: 1267 init1: 1267 opt: 1267 Z-score: 1544.4 bits: 292.4 E(85289): 2.8e-79 Smith-Waterman score: 1267; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183) 10 20 30 40 50 60 pF1KB8 MMQICDTYNQKHSLFNAMNRFIGAVNNMDQTVMVPSLLRDVPLADPGLDNDVGVEVGGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMQICDTYNQKHSLFNAMNRFIGAVNNMDQTVMVPSLLRDVPLADPGLDNDVGVEVGGSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GCLEERTPPVPDSGSANGSFFAPSRDMYSHYVLLKSIRNDIEWGVLHQPPPPAGSEEGSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GCLEERTPPVPDSGSANGSFFAPSRDMYSHYVLLKSIRNDIEWGVLHQPPPPAGSEEGSA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 WKSKDILVDLGHLEGADAGEEDLEQQFHYHLRGLHTVLSKLTRKANILTNRYKQEIGFGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WKSKDILVDLGHLEGADAGEEDLEQQFHYHLRGLHTVLSKLTRKANILTNRYKQEIGFGN 130 140 150 160 170 180 pF1KB8 WGH ::: NP_001 WGH >>NP_067065 (OMIM: 300961) mid1-interacting protein 1 [H (183 aa) initn: 1267 init1: 1267 opt: 1267 Z-score: 1544.4 bits: 292.4 E(85289): 2.8e-79 Smith-Waterman score: 1267; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183) 10 20 30 40 50 60 pF1KB8 MMQICDTYNQKHSLFNAMNRFIGAVNNMDQTVMVPSLLRDVPLADPGLDNDVGVEVGGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 MMQICDTYNQKHSLFNAMNRFIGAVNNMDQTVMVPSLLRDVPLADPGLDNDVGVEVGGSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GCLEERTPPVPDSGSANGSFFAPSRDMYSHYVLLKSIRNDIEWGVLHQPPPPAGSEEGSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 GCLEERTPPVPDSGSANGSFFAPSRDMYSHYVLLKSIRNDIEWGVLHQPPPPAGSEEGSA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 WKSKDILVDLGHLEGADAGEEDLEQQFHYHLRGLHTVLSKLTRKANILTNRYKQEIGFGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 WKSKDILVDLGHLEGADAGEEDLEQQFHYHLRGLHTVLSKLTRKANILTNRYKQEIGFGN 130 140 150 160 170 180 pF1KB8 WGH ::: NP_067 WGH >>NP_003242 (OMIM: 601926) thyroid hormone-inducible hep (146 aa) initn: 286 init1: 152 opt: 152 Z-score: 191.5 bits: 41.7 E(85289): 0.00063 Smith-Waterman score: 269; 33.5% identity (60.3% similar) in 179 aa overlap (2-177:1-143) 10 20 30 40 50 60 pF1KB8 MMQICDTYNQKHSLFNAMNRFIGAVNNMDQTVMVPSLLRDVPLADPGLDNDVGVEVGGSG ::. :. :...:.:. . :.::.:.::.::::::: :. :: NP_003 MQVLTKRYPKNCLLTVMDRYAAEVHNMEQVVMIPSLLRDVQLSGPG------------- 10 20 30 40 70 80 90 100 110 pF1KB8 GCLEERTPPVPDSGSANGSFFAPSRDMYSHYVLLKSIRNDIEWGVLHQPP---PPAGSEE :.:.. :: :.:.....::.: :.. :.: . ::::: NP_003 -------------GQAQAE--AP--DLYTYFTMLKAICVDVDHGLLPREEWQAKVAGSEE 50 60 70 80 120 130 140 150 160 170 pF1KB8 GSAWKSKDILVDLGHLEGADAGEEDLEQQFHYHLRGLHTVLSKLTRKANILTNRYKQEIG ... ..... . :.: .:: ::: ::: :. .:: .: .::.::. .: .:.. : NP_003 NGTAETEEV-----EDESA-SGELDLEAQFHLHFSSLHHILMHLTEKAQEVTRKYQEMTG 90 100 110 120 130 140 180 pF1KB8 FGNWGH NP_003 QVW 183 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:07:47 2016 done: Fri Nov 4 15:07:48 2016 Total Scan time: 5.210 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]