FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8741, 139 aa 1>>>pF1KB8741 139 - 139 aa - 139 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4171+/-0.000251; mu= 7.8898+/- 0.016 mean_var=97.1613+/-19.355, 0's: 0 Z-trim(123.0): 13 B-trim: 390 in 1/52 Lambda= 0.130115 statistics sampled from 42042 (42055) to 42042 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.827), E-opt: 0.2 (0.493), width: 16 Scan time: 5.560 The best scores are: opt bits E(85289) XP_016857180 (OMIM: 611882) PREDICTED: proline-ric ( 139) 950 187.0 8.4e-48 NP_060231 (OMIM: 611882) proline-rich nuclear rece ( 139) 950 187.0 8.4e-48 NP_006804 (OMIM: 606714) proline-rich nuclear rece ( 327) 295 64.2 1.8e-10 >>XP_016857180 (OMIM: 611882) PREDICTED: proline-rich nu (139 aa) initn: 950 init1: 950 opt: 950 Z-score: 979.2 bits: 187.0 E(85289): 8.4e-48 Smith-Waterman score: 950; 100.0% identity (100.0% similar) in 139 aa overlap (1-139:1-139) 10 20 30 40 50 60 pF1KB8 MGGGERYNIPAPQSRNVSKNQQQLNRQKTKEQNSQMKIVHKKKERGHGYNSSAAAWQAMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGGGERYNIPAPQSRNVSKNQQQLNRQKTKEQNSQMKIVHKKKERGHGYNSSAAAWQAMQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NGGKNKNFPNNQSWNSSLSGPRLLFKSQANQNYAGAKFSEPPSPSVLPKPPSHWVPVSFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGGKNKNFPNNQSWNSSLSGPRLLFKSQANQNYAGAKFSEPPSPSVLPKPPSHWVPVSFN 70 80 90 100 110 120 130 pF1KB8 PSDKEIMTFQLKTLLKVQV ::::::::::::::::::: XP_016 PSDKEIMTFQLKTLLKVQV 130 >>NP_060231 (OMIM: 611882) proline-rich nuclear receptor (139 aa) initn: 950 init1: 950 opt: 950 Z-score: 979.2 bits: 187.0 E(85289): 8.4e-48 Smith-Waterman score: 950; 100.0% identity (100.0% similar) in 139 aa overlap (1-139:1-139) 10 20 30 40 50 60 pF1KB8 MGGGERYNIPAPQSRNVSKNQQQLNRQKTKEQNSQMKIVHKKKERGHGYNSSAAAWQAMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MGGGERYNIPAPQSRNVSKNQQQLNRQKTKEQNSQMKIVHKKKERGHGYNSSAAAWQAMQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NGGKNKNFPNNQSWNSSLSGPRLLFKSQANQNYAGAKFSEPPSPSVLPKPPSHWVPVSFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 NGGKNKNFPNNQSWNSSLSGPRLLFKSQANQNYAGAKFSEPPSPSVLPKPPSHWVPVSFN 70 80 90 100 110 120 130 pF1KB8 PSDKEIMTFQLKTLLKVQV ::::::::::::::::::: NP_060 PSDKEIMTFQLKTLLKVQV 130 >>NP_006804 (OMIM: 606714) proline-rich nuclear receptor (327 aa) initn: 271 init1: 186 opt: 295 Z-score: 309.1 bits: 64.2 E(85289): 1.8e-10 Smith-Waterman score: 295; 39.9% identity (70.6% similar) in 143 aa overlap (1-138:186-326) 10 20 pF1KB8 MGGGERYNIPAPQ-SRNVSKNQQ-QLNRQK :: .:. .: : ... .: ..:::: NP_006 GTEGASPDLAPLRPAAPGQTPLRKEVLKSKMGKSEKIALPHGQLVHGIHLYEQPKINRQK 160 170 180 190 200 210 30 40 50 60 70 80 pF1KB8 TKEQNSQMKIVHKKKERGHGYNSSAAAWQAMQNGGKNKNFPNNQSW-NSSLSGPRLLFKS .: . ::. :..... ...:... . .:. : : : :... :: :. .: . NP_006 SKYNLPLTKITSAKRNENNFWQDSVSS-DRIQKQEK-KPFKNTENIKNSHLKKSAFLTEV 220 230 240 250 260 270 90 100 110 120 130 pF1KB8 QANQNYAGAKFSEPPSPSVLPKPPSHWVPVSFNPSD--KEIMTFQLKTLLKVQV . ..::::::::.::::::::::::::. . . :. .:.:. .:::::::: NP_006 SQKENYAGAKFSDPPSPSVLPKPPSHWMGSTVENSNQNRELMAVHLKTLLKVQT 280 290 300 310 320 139 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:08:17 2016 done: Fri Nov 4 15:08:18 2016 Total Scan time: 5.560 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]