FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8750, 140 aa 1>>>pF1KB8750 140 - 140 aa - 140 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4094+/-0.000391; mu= 9.8964+/- 0.024 mean_var=58.4092+/-11.682, 0's: 0 Z-trim(112.0): 20 B-trim: 709 in 2/51 Lambda= 0.167816 statistics sampled from 20747 (20766) to 20747 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.243), width: 16 Scan time: 4.270 The best scores are: opt bits E(85289) NP_037380 (OMIM: 605811) NTF2-related export prote ( 140) 935 234.6 3.9e-62 XP_011527532 (OMIM: 605811) PREDICTED: NTF2-relate ( 140) 935 234.6 3.9e-62 NP_001229546 (OMIM: 300320) NTF2-related export pr ( 142) 744 188.4 3.3e-48 NP_061168 (OMIM: 300320) NTF2-related export prote ( 197) 744 188.4 4.4e-48 XP_011529291 (OMIM: 300320) PREDICTED: NTF2-relate ( 141) 739 187.2 7.6e-48 XP_016885137 (OMIM: 300320) PREDICTED: NTF2-relate ( 114) 592 151.6 3.2e-37 NP_001229547 (OMIM: 300320) NTF2-related export pr ( 114) 592 151.6 3.2e-37 NP_001308968 (OMIM: 605813) nuclear transport fact ( 127) 159 46.7 1.3e-05 NP_005787 (OMIM: 605813) nuclear transport factor ( 127) 159 46.7 1.3e-05 NP_001308970 (OMIM: 605813) nuclear transport fact ( 127) 159 46.7 1.3e-05 NP_001308969 (OMIM: 605813) nuclear transport fact ( 127) 159 46.7 1.3e-05 NP_001308967 (OMIM: 605813) nuclear transport fact ( 127) 159 46.7 1.3e-05 XP_006714813 (OMIM: 608431) PREDICTED: ras GTPase- ( 466) 131 40.1 0.0046 NP_938405 (OMIM: 608431) ras GTPase-activating pro ( 466) 131 40.1 0.0046 XP_006714812 (OMIM: 608431) PREDICTED: ras GTPase- ( 466) 131 40.1 0.0046 XP_016864411 (OMIM: 608431) PREDICTED: ras GTPase- ( 466) 131 40.1 0.0046 XP_016864412 (OMIM: 608431) PREDICTED: ras GTPase- ( 466) 131 40.1 0.0046 NP_005745 (OMIM: 608431) ras GTPase-activating pro ( 466) 131 40.1 0.0046 >>NP_037380 (OMIM: 605811) NTF2-related export protein 1 (140 aa) initn: 935 init1: 935 opt: 935 Z-score: 1236.5 bits: 234.6 E(85289): 3.9e-62 Smith-Waterman score: 935; 100.0% identity (100.0% similar) in 140 aa overlap (1-140:1-140) 10 20 30 40 50 60 pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 FFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQAS 70 80 90 100 110 120 130 140 pF1KB8 PSNTVWKIASDCFRFQDWAS :::::::::::::::::::: NP_037 PSNTVWKIASDCFRFQDWAS 130 140 >>XP_011527532 (OMIM: 605811) PREDICTED: NTF2-related ex (140 aa) initn: 935 init1: 935 opt: 935 Z-score: 1236.5 bits: 234.6 E(85289): 3.9e-62 Smith-Waterman score: 935; 100.0% identity (100.0% similar) in 140 aa overlap (1-140:1-140) 10 20 30 40 50 60 pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQAS 70 80 90 100 110 120 130 140 pF1KB8 PSNTVWKIASDCFRFQDWAS :::::::::::::::::::: XP_011 PSNTVWKIASDCFRFQDWAS 130 140 >>NP_001229546 (OMIM: 300320) NTF2-related export protei (142 aa) initn: 738 init1: 738 opt: 744 Z-score: 986.5 bits: 188.4 E(85289): 3.3e-48 Smith-Waterman score: 744; 75.4% identity (92.8% similar) in 138 aa overlap (3-140:4-141) 10 20 30 40 50 pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLS :.::::::::::::::::::.:: ::::::: :.:::. :::.:::::::: ..:. NP_001 MATSLDFKTYVDQACRAAEEFVNIYYETMDKRRRALTRLYLDKATLIWNGNAVSGLDALN 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 EFFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQA .::. :::::::....::::::..:: :::::::: :.:::.::::. :::::.::::. NP_001 NFFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDGNKQHFFNQNFLLTAQS 70 80 90 100 110 120 120 130 140 pF1KB8 SPSNTVWKIASDCFRFQDWAS .:.::::::::::::::::.: NP_001 TPNNTVWKIASDCFRFQDWSSS 130 140 >>NP_061168 (OMIM: 300320) NTF2-related export protein 2 (197 aa) initn: 755 init1: 738 opt: 744 Z-score: 984.2 bits: 188.4 E(85289): 4.4e-48 Smith-Waterman score: 744; 75.4% identity (92.8% similar) in 138 aa overlap (3-140:59-196) 10 20 30 pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRR :.::::::::::::::::::.:: :::::: NP_061 SHSSPADRTREEVVTPTLPEHTATRSQMATSLDFKTYVDQACRAAEEFVNIYYETMDKRR 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB8 RLLSRLYMGTATLVWNGNAVSGQESLSEFFEMLPSSEFQISVVDCQPVHDEATPSQTTVL : :.:::. :::.:::::::: ..:..::. :::::::....::::::..:: :::::: NP_061 RALTRLYLDKATLIWNGNAVSGLDALNNFFDTLPSSEFQVNMLDCQPVHEQATQSQTTVL 90 100 110 120 130 140 100 110 120 130 140 pF1KB8 VVICGSVKFEGNKQRDFNQNFILTAQASPSNTVWKIASDCFRFQDWAS :: :.:::.::::. :::::.::::..:.::::::::::::::::.: NP_061 VVTSGTVKFDGNKQHFFNQNFLLTAQSTPNNTVWKIASDCFRFQDWSSS 150 160 170 180 190 >>XP_011529291 (OMIM: 300320) PREDICTED: NTF2-related ex (141 aa) initn: 738 init1: 738 opt: 739 Z-score: 980.0 bits: 187.2 E(85289): 7.6e-48 Smith-Waterman score: 739; 74.3% identity (90.7% similar) in 140 aa overlap (1-140:1-140) 10 20 30 40 50 60 pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE : ::::::::::::::::::.:: ::::::: :.:::. :::.:::::::: ..:.. XP_011 MRRKDFKTYVDQACRAAEEFVNIYYETMDKRRRALTRLYLDKATLIWNGNAVSGLDALNN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQAS ::. :::::::....::::::..:: :::::::: :.:::.::::. :::::.::::.. XP_011 FFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDGNKQHFFNQNFLLTAQST 70 80 90 100 110 120 130 140 pF1KB8 PSNTVWKIASDCFRFQDWAS :.::::::::::::::::.: XP_011 PNNTVWKIASDCFRFQDWSSS 130 140 >>XP_016885137 (OMIM: 300320) PREDICTED: NTF2-related ex (114 aa) initn: 602 init1: 592 opt: 592 Z-score: 789.2 bits: 151.6 E(85289): 3.2e-37 Smith-Waterman score: 592; 72.6% identity (92.0% similar) in 113 aa overlap (28-140:1-113) 10 20 30 40 50 60 pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE :::::: :.:::. :::.:::::::: ..:.. XP_016 MDKRRRALTRLYLDKATLIWNGNAVSGLDALNN 10 20 30 70 80 90 100 110 120 pF1KB8 FFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQAS ::. :::::::....::::::..:: :::::::: :.:::.::::. :::::.::::.. XP_016 FFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDGNKQHFFNQNFLLTAQST 40 50 60 70 80 90 130 140 pF1KB8 PSNTVWKIASDCFRFQDWAS :.::::::::::::::::.: XP_016 PNNTVWKIASDCFRFQDWSSS 100 110 >>NP_001229547 (OMIM: 300320) NTF2-related export protei (114 aa) initn: 602 init1: 592 opt: 592 Z-score: 789.2 bits: 151.6 E(85289): 3.2e-37 Smith-Waterman score: 592; 72.6% identity (92.0% similar) in 113 aa overlap (28-140:1-113) 10 20 30 40 50 60 pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE :::::: :.:::. :::.:::::::: ..:.. NP_001 MDKRRRALTRLYLDKATLIWNGNAVSGLDALNN 10 20 30 70 80 90 100 110 120 pF1KB8 FFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQAS ::. :::::::....::::::..:: :::::::: :.:::.::::. :::::.::::.. NP_001 FFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDGNKQHFFNQNFLLTAQST 40 50 60 70 80 90 130 140 pF1KB8 PSNTVWKIASDCFRFQDWAS :.::::::::::::::::.: NP_001 PNNTVWKIASDCFRFQDWSSS 100 110 >>NP_001308968 (OMIM: 605813) nuclear transport factor 2 (127 aa) initn: 91 init1: 80 opt: 159 Z-score: 221.8 bits: 46.7 E(85289): 1.3e-05 Smith-Waterman score: 159; 26.3% identity (59.3% similar) in 118 aa overlap (20-135:14-121) 10 20 30 40 50 60 pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE :.. :: .:. : :. .:. .. :.:.:. .:. .. : NP_001 MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQQFQGKAAIVE 10 20 30 40 50 70 80 90 100 110 pF1KB8 FFEMLPSSEFQISVV--DCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQ . :: ...: :.. : ::. : . .. .. :..: . . :.: :.: NP_001 KLSSLPFQKIQHSITAQDHQPTPD------SCIISMVVGQLKADEDPIMGFHQMFLL--- 60 70 80 90 100 120 130 140 pF1KB8 ASPSNTVWKIASDCFRFQDWAS . : .: ..: ::. NP_001 -KNINDAWVCTNDMFRLALHNFG 110 120 >>NP_005787 (OMIM: 605813) nuclear transport factor 2 [H (127 aa) initn: 91 init1: 80 opt: 159 Z-score: 221.8 bits: 46.7 E(85289): 1.3e-05 Smith-Waterman score: 159; 26.3% identity (59.3% similar) in 118 aa overlap (20-135:14-121) 10 20 30 40 50 60 pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE :.. :: .:. : :. .:. .. :.:.:. .:. .. : NP_005 MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQQFQGKAAIVE 10 20 30 40 50 70 80 90 100 110 pF1KB8 FFEMLPSSEFQISVV--DCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQ . :: ...: :.. : ::. : . .. .. :..: . . :.: :.: NP_005 KLSSLPFQKIQHSITAQDHQPTPD------SCIISMVVGQLKADEDPIMGFHQMFLL--- 60 70 80 90 100 120 130 140 pF1KB8 ASPSNTVWKIASDCFRFQDWAS . : .: ..: ::. NP_005 -KNINDAWVCTNDMFRLALHNFG 110 120 >>NP_001308970 (OMIM: 605813) nuclear transport factor 2 (127 aa) initn: 91 init1: 80 opt: 159 Z-score: 221.8 bits: 46.7 E(85289): 1.3e-05 Smith-Waterman score: 159; 26.3% identity (59.3% similar) in 118 aa overlap (20-135:14-121) 10 20 30 40 50 60 pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE :.. :: .:. : :. .:. .. :.:.:. .:. .. : NP_001 MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQQFQGKAAIVE 10 20 30 40 50 70 80 90 100 110 pF1KB8 FFEMLPSSEFQISVV--DCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQ . :: ...: :.. : ::. : . .. .. :..: . . :.: :.: NP_001 KLSSLPFQKIQHSITAQDHQPTPD------SCIISMVVGQLKADEDPIMGFHQMFLL--- 60 70 80 90 100 120 130 140 pF1KB8 ASPSNTVWKIASDCFRFQDWAS . : .: ..: ::. NP_001 -KNINDAWVCTNDMFRLALHNFG 110 120 140 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:13:30 2016 done: Fri Nov 4 15:13:31 2016 Total Scan time: 4.270 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]