FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8750, 140 aa
1>>>pF1KB8750 140 - 140 aa - 140 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4094+/-0.000391; mu= 9.8964+/- 0.024
mean_var=58.4092+/-11.682, 0's: 0 Z-trim(112.0): 20 B-trim: 709 in 2/51
Lambda= 0.167816
statistics sampled from 20747 (20766) to 20747 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.243), width: 16
Scan time: 4.270
The best scores are: opt bits E(85289)
NP_037380 (OMIM: 605811) NTF2-related export prote ( 140) 935 234.6 3.9e-62
XP_011527532 (OMIM: 605811) PREDICTED: NTF2-relate ( 140) 935 234.6 3.9e-62
NP_001229546 (OMIM: 300320) NTF2-related export pr ( 142) 744 188.4 3.3e-48
NP_061168 (OMIM: 300320) NTF2-related export prote ( 197) 744 188.4 4.4e-48
XP_011529291 (OMIM: 300320) PREDICTED: NTF2-relate ( 141) 739 187.2 7.6e-48
XP_016885137 (OMIM: 300320) PREDICTED: NTF2-relate ( 114) 592 151.6 3.2e-37
NP_001229547 (OMIM: 300320) NTF2-related export pr ( 114) 592 151.6 3.2e-37
NP_001308968 (OMIM: 605813) nuclear transport fact ( 127) 159 46.7 1.3e-05
NP_005787 (OMIM: 605813) nuclear transport factor ( 127) 159 46.7 1.3e-05
NP_001308970 (OMIM: 605813) nuclear transport fact ( 127) 159 46.7 1.3e-05
NP_001308969 (OMIM: 605813) nuclear transport fact ( 127) 159 46.7 1.3e-05
NP_001308967 (OMIM: 605813) nuclear transport fact ( 127) 159 46.7 1.3e-05
XP_006714813 (OMIM: 608431) PREDICTED: ras GTPase- ( 466) 131 40.1 0.0046
NP_938405 (OMIM: 608431) ras GTPase-activating pro ( 466) 131 40.1 0.0046
XP_006714812 (OMIM: 608431) PREDICTED: ras GTPase- ( 466) 131 40.1 0.0046
XP_016864411 (OMIM: 608431) PREDICTED: ras GTPase- ( 466) 131 40.1 0.0046
XP_016864412 (OMIM: 608431) PREDICTED: ras GTPase- ( 466) 131 40.1 0.0046
NP_005745 (OMIM: 608431) ras GTPase-activating pro ( 466) 131 40.1 0.0046
>>NP_037380 (OMIM: 605811) NTF2-related export protein 1 (140 aa)
initn: 935 init1: 935 opt: 935 Z-score: 1236.5 bits: 234.6 E(85289): 3.9e-62
Smith-Waterman score: 935; 100.0% identity (100.0% similar) in 140 aa overlap (1-140:1-140)
10 20 30 40 50 60
pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 FFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 FFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQAS
70 80 90 100 110 120
130 140
pF1KB8 PSNTVWKIASDCFRFQDWAS
::::::::::::::::::::
NP_037 PSNTVWKIASDCFRFQDWAS
130 140
>>XP_011527532 (OMIM: 605811) PREDICTED: NTF2-related ex (140 aa)
initn: 935 init1: 935 opt: 935 Z-score: 1236.5 bits: 234.6 E(85289): 3.9e-62
Smith-Waterman score: 935; 100.0% identity (100.0% similar) in 140 aa overlap (1-140:1-140)
10 20 30 40 50 60
pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 FFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQAS
70 80 90 100 110 120
130 140
pF1KB8 PSNTVWKIASDCFRFQDWAS
::::::::::::::::::::
XP_011 PSNTVWKIASDCFRFQDWAS
130 140
>>NP_001229546 (OMIM: 300320) NTF2-related export protei (142 aa)
initn: 738 init1: 738 opt: 744 Z-score: 986.5 bits: 188.4 E(85289): 3.3e-48
Smith-Waterman score: 744; 75.4% identity (92.8% similar) in 138 aa overlap (3-140:4-141)
10 20 30 40 50
pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLS
:.::::::::::::::::::.:: ::::::: :.:::. :::.:::::::: ..:.
NP_001 MATSLDFKTYVDQACRAAEEFVNIYYETMDKRRRALTRLYLDKATLIWNGNAVSGLDALN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 EFFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQA
.::. :::::::....::::::..:: :::::::: :.:::.::::. :::::.::::.
NP_001 NFFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDGNKQHFFNQNFLLTAQS
70 80 90 100 110 120
120 130 140
pF1KB8 SPSNTVWKIASDCFRFQDWAS
.:.::::::::::::::::.:
NP_001 TPNNTVWKIASDCFRFQDWSSS
130 140
>>NP_061168 (OMIM: 300320) NTF2-related export protein 2 (197 aa)
initn: 755 init1: 738 opt: 744 Z-score: 984.2 bits: 188.4 E(85289): 4.4e-48
Smith-Waterman score: 744; 75.4% identity (92.8% similar) in 138 aa overlap (3-140:59-196)
10 20 30
pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRR
:.::::::::::::::::::.:: ::::::
NP_061 SHSSPADRTREEVVTPTLPEHTATRSQMATSLDFKTYVDQACRAAEEFVNIYYETMDKRR
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB8 RLLSRLYMGTATLVWNGNAVSGQESLSEFFEMLPSSEFQISVVDCQPVHDEATPSQTTVL
: :.:::. :::.:::::::: ..:..::. :::::::....::::::..:: ::::::
NP_061 RALTRLYLDKATLIWNGNAVSGLDALNNFFDTLPSSEFQVNMLDCQPVHEQATQSQTTVL
90 100 110 120 130 140
100 110 120 130 140
pF1KB8 VVICGSVKFEGNKQRDFNQNFILTAQASPSNTVWKIASDCFRFQDWAS
:: :.:::.::::. :::::.::::..:.::::::::::::::::.:
NP_061 VVTSGTVKFDGNKQHFFNQNFLLTAQSTPNNTVWKIASDCFRFQDWSSS
150 160 170 180 190
>>XP_011529291 (OMIM: 300320) PREDICTED: NTF2-related ex (141 aa)
initn: 738 init1: 738 opt: 739 Z-score: 980.0 bits: 187.2 E(85289): 7.6e-48
Smith-Waterman score: 739; 74.3% identity (90.7% similar) in 140 aa overlap (1-140:1-140)
10 20 30 40 50 60
pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE
: ::::::::::::::::::.:: ::::::: :.:::. :::.:::::::: ..:..
XP_011 MRRKDFKTYVDQACRAAEEFVNIYYETMDKRRRALTRLYLDKATLIWNGNAVSGLDALNN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 FFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQAS
::. :::::::....::::::..:: :::::::: :.:::.::::. :::::.::::..
XP_011 FFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDGNKQHFFNQNFLLTAQST
70 80 90 100 110 120
130 140
pF1KB8 PSNTVWKIASDCFRFQDWAS
:.::::::::::::::::.:
XP_011 PNNTVWKIASDCFRFQDWSSS
130 140
>>XP_016885137 (OMIM: 300320) PREDICTED: NTF2-related ex (114 aa)
initn: 602 init1: 592 opt: 592 Z-score: 789.2 bits: 151.6 E(85289): 3.2e-37
Smith-Waterman score: 592; 72.6% identity (92.0% similar) in 113 aa overlap (28-140:1-113)
10 20 30 40 50 60
pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE
:::::: :.:::. :::.:::::::: ..:..
XP_016 MDKRRRALTRLYLDKATLIWNGNAVSGLDALNN
10 20 30
70 80 90 100 110 120
pF1KB8 FFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQAS
::. :::::::....::::::..:: :::::::: :.:::.::::. :::::.::::..
XP_016 FFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDGNKQHFFNQNFLLTAQST
40 50 60 70 80 90
130 140
pF1KB8 PSNTVWKIASDCFRFQDWAS
:.::::::::::::::::.:
XP_016 PNNTVWKIASDCFRFQDWSSS
100 110
>>NP_001229547 (OMIM: 300320) NTF2-related export protei (114 aa)
initn: 602 init1: 592 opt: 592 Z-score: 789.2 bits: 151.6 E(85289): 3.2e-37
Smith-Waterman score: 592; 72.6% identity (92.0% similar) in 113 aa overlap (28-140:1-113)
10 20 30 40 50 60
pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE
:::::: :.:::. :::.:::::::: ..:..
NP_001 MDKRRRALTRLYLDKATLIWNGNAVSGLDALNN
10 20 30
70 80 90 100 110 120
pF1KB8 FFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQAS
::. :::::::....::::::..:: :::::::: :.:::.::::. :::::.::::..
NP_001 FFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDGNKQHFFNQNFLLTAQST
40 50 60 70 80 90
130 140
pF1KB8 PSNTVWKIASDCFRFQDWAS
:.::::::::::::::::.:
NP_001 PNNTVWKIASDCFRFQDWSSS
100 110
>>NP_001308968 (OMIM: 605813) nuclear transport factor 2 (127 aa)
initn: 91 init1: 80 opt: 159 Z-score: 221.8 bits: 46.7 E(85289): 1.3e-05
Smith-Waterman score: 159; 26.3% identity (59.3% similar) in 118 aa overlap (20-135:14-121)
10 20 30 40 50 60
pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE
:.. :: .:. : :. .:. .. :.:.:. .:. .. :
NP_001 MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQQFQGKAAIVE
10 20 30 40 50
70 80 90 100 110
pF1KB8 FFEMLPSSEFQISVV--DCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQ
. :: ...: :.. : ::. : . .. .. :..: . . :.: :.:
NP_001 KLSSLPFQKIQHSITAQDHQPTPD------SCIISMVVGQLKADEDPIMGFHQMFLL---
60 70 80 90 100
120 130 140
pF1KB8 ASPSNTVWKIASDCFRFQDWAS
. : .: ..: ::.
NP_001 -KNINDAWVCTNDMFRLALHNFG
110 120
>>NP_005787 (OMIM: 605813) nuclear transport factor 2 [H (127 aa)
initn: 91 init1: 80 opt: 159 Z-score: 221.8 bits: 46.7 E(85289): 1.3e-05
Smith-Waterman score: 159; 26.3% identity (59.3% similar) in 118 aa overlap (20-135:14-121)
10 20 30 40 50 60
pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE
:.. :: .:. : :. .:. .. :.:.:. .:. .. :
NP_005 MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQQFQGKAAIVE
10 20 30 40 50
70 80 90 100 110
pF1KB8 FFEMLPSSEFQISVV--DCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQ
. :: ...: :.. : ::. : . .. .. :..: . . :.: :.:
NP_005 KLSSLPFQKIQHSITAQDHQPTPD------SCIISMVVGQLKADEDPIMGFHQMFLL---
60 70 80 90 100
120 130 140
pF1KB8 ASPSNTVWKIASDCFRFQDWAS
. : .: ..: ::.
NP_005 -KNINDAWVCTNDMFRLALHNFG
110 120
>>NP_001308970 (OMIM: 605813) nuclear transport factor 2 (127 aa)
initn: 91 init1: 80 opt: 159 Z-score: 221.8 bits: 46.7 E(85289): 1.3e-05
Smith-Waterman score: 159; 26.3% identity (59.3% similar) in 118 aa overlap (20-135:14-121)
10 20 30 40 50 60
pF1KB8 MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE
:.. :: .:. : :. .:. .. :.:.:. .:. .. :
NP_001 MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQQFQGKAAIVE
10 20 30 40 50
70 80 90 100 110
pF1KB8 FFEMLPSSEFQISVV--DCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQ
. :: ...: :.. : ::. : . .. .. :..: . . :.: :.:
NP_001 KLSSLPFQKIQHSITAQDHQPTPD------SCIISMVVGQLKADEDPIMGFHQMFLL---
60 70 80 90 100
120 130 140
pF1KB8 ASPSNTVWKIASDCFRFQDWAS
. : .: ..: ::.
NP_001 -KNINDAWVCTNDMFRLALHNFG
110 120
140 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:13:30 2016 done: Fri Nov 4 15:13:31 2016
Total Scan time: 4.270 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]