FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8753, 196 aa 1>>>pF1KB8753 196 - 196 aa - 196 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2842+/-0.000799; mu= 13.4696+/- 0.048 mean_var=77.3551+/-16.325, 0's: 0 Z-trim(108.6): 119 B-trim: 437 in 2/48 Lambda= 0.145824 statistics sampled from 10157 (10300) to 10157 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.703), E-opt: 0.2 (0.316), width: 16 Scan time: 1.830 The best scores are: opt bits E(32554) CCDS9419.1 ARL11 gene_id:115761|Hs108|chr13 ( 196) 1288 280.0 6.5e-76 CCDS3192.1 ARL14 gene_id:80117|Hs108|chr3 ( 192) 514 117.1 6.6e-27 CCDS9695.1 ARF6 gene_id:382|Hs108|chr14 ( 175) 472 108.3 2.8e-24 CCDS7538.1 ARL3 gene_id:403|Hs108|chr10 ( 182) 466 107.0 7e-24 CCDS8088.1 ARL2 gene_id:402|Hs108|chr11 ( 184) 455 104.7 3.5e-23 CCDS63169.1 ARL4C gene_id:10123|Hs108|chr2 ( 201) 454 104.5 4.3e-23 CCDS34745.1 ARF5 gene_id:381|Hs108|chr7 ( 180) 450 103.7 7.1e-23 CCDS8774.1 ARF3 gene_id:377|Hs108|chr12 ( 181) 449 103.5 8.3e-23 CCDS2512.1 ARL4C gene_id:10123|Hs108|chr2 ( 192) 449 103.5 8.7e-23 CCDS1565.1 ARF1 gene_id:375|Hs108|chr1 ( 181) 443 102.2 2e-22 CCDS11463.1 ARL4D gene_id:379|Hs108|chr17 ( 201) 440 101.6 3.3e-22 CCDS2195.1 ARL5A gene_id:26225|Hs108|chr2 ( 179) 432 99.9 9.8e-22 CCDS2884.1 ARF4 gene_id:378|Hs108|chr3 ( 180) 427 98.8 2e-21 CCDS44958.1 ARL1 gene_id:400|Hs108|chr12 ( 181) 418 96.9 7.6e-21 CCDS5359.1 ARL4A gene_id:10124|Hs108|chr7 ( 200) 413 95.9 1.7e-20 CCDS3987.1 TRIM23 gene_id:373|Hs108|chr5 ( 574) 415 96.7 2.9e-20 CCDS7131.1 ARL5B gene_id:221079|Hs108|chr10 ( 179) 405 94.2 5e-20 CCDS45664.1 ARL5C gene_id:390790|Hs108|chr17 ( 179) 382 89.4 1.4e-18 CCDS43322.1 TRIM23 gene_id:373|Hs108|chr5 ( 569) 388 91.0 1.5e-18 CCDS3986.1 TRIM23 gene_id:373|Hs108|chr5 ( 546) 360 85.1 8.4e-17 CCDS2928.1 ARL6 gene_id:84100|Hs108|chr3 ( 186) 354 83.5 8.8e-17 CCDS46425.1 ARL5A gene_id:26225|Hs108|chr2 ( 142) 348 82.1 1.7e-16 CCDS2566.1 ARL8B gene_id:55207|Hs108|chr3 ( 186) 348 82.2 2.1e-16 CCDS1421.1 ARL8A gene_id:127829|Hs108|chr1 ( 186) 347 82.0 2.4e-16 CCDS13533.1 ARFRP1 gene_id:10139|Hs108|chr20 ( 201) 332 78.9 2.3e-15 CCDS2925.1 ARL13B gene_id:200894|Hs108|chr3 ( 428) 325 77.7 1.1e-14 CCDS46630.1 ARFRP1 gene_id:10139|Hs108|chr20 ( 173) 314 75.0 2.8e-14 CCDS73510.1 ARL1 gene_id:400|Hs108|chr12 ( 135) 304 72.9 1e-13 CCDS4177.1 SAR1B gene_id:51128|Hs108|chr5 ( 198) 306 73.4 1e-13 CCDS7298.1 SAR1A gene_id:56681|Hs108|chr10 ( 198) 302 72.6 1.8e-13 CCDS55770.1 ARL2 gene_id:402|Hs108|chr11 ( 157) 290 70.0 8.7e-13 CCDS4400.1 ARL10 gene_id:285598|Hs108|chr5 ( 244) 290 70.1 1.2e-12 CCDS54850.1 ARL15 gene_id:54622|Hs108|chr5 ( 204) 286 69.2 1.9e-12 CCDS73004.1 ARL8A gene_id:127829|Hs108|chr1 ( 147) 279 67.6 4.1e-12 CCDS68172.1 ARFRP1 gene_id:10139|Hs108|chr20 ( 154) 273 66.4 1e-11 >>CCDS9419.1 ARL11 gene_id:115761|Hs108|chr13 (196 aa) initn: 1288 init1: 1288 opt: 1288 Z-score: 1476.4 bits: 280.0 E(32554): 6.5e-76 Smith-Waterman score: 1288; 99.5% identity (99.5% similar) in 196 aa overlap (1-196:1-196) 10 20 30 40 50 60 pF1KB8 MGSVNSRGHKAEAQVVMMGLDSAGKTTLLYKLKGHQLVETLPTVGFNVEPLKAPGHVSLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS94 MGSVNSRGHKAEAQVVMMGLDSAGKTTLLYKLKGHQLVETLPTVGFNVEPLKAPGHVSLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 LWDVGGQAPLRASWKDYLEGTDILVYVLDSTDEARLPESAAELTEVLNDPNMAGVPFLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS94 LWDVGGQAPLRASWKDYLEGTDILVYVLDSTDEARLPESAAELTEVLNDPNMAGVPFLVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ANKQEAPDALPLLKIRNRLSLERFQDHRWELRGCSALTGEGLPEALQSLWSLLKSRSCMC ::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::: CCDS94 ANKQEAPDALPLLKIRNRLSLERFQDHCWELRGCSALTGEGLPEALQSLWSLLKSRSCMC 130 140 150 160 170 180 190 pF1KB8 LQARAHGAERGDSKRS :::::::::::::::: CCDS94 LQARAHGAERGDSKRS 190 >>CCDS3192.1 ARL14 gene_id:80117|Hs108|chr3 (192 aa) initn: 530 init1: 416 opt: 514 Z-score: 596.5 bits: 117.1 E(32554): 6.6e-27 Smith-Waterman score: 514; 45.8% identity (76.8% similar) in 177 aa overlap (1-175:1-177) 10 20 30 40 50 pF1KB8 MGSVNSRGHKA-EAQVVMMGLDSAGKTTLLYKLKGHQLVETLPTVGFNVEPLKAPGHVSL :::..:.. .. .:::...:::::::.::::::: . . :.::.::::: .. ..:: CCDS31 MGSLGSKNPQTKQAQVLLLGLDSAGKSTLLYKLKLAKDITTIPTIGFNVEMIELERNLSL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 TLWDVGGQAPLRASWKDYLEGTDILVYVLDSTDEARLPESAAELTEVLNDPNMAGVPFLV :.:::::: .:. : : :.:: ::::.::::. :: :: .. ..:.. .. .:: .. CCDS31 TVWDVGGQEKMRTVWGCYCENTDGLVYVVDSTDKQRLEESQRQFEHILKNEHIKNVPVVL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 LANKQEAPDALPLLKIRNRLSLERF-QDHRWELRGCSALTGEGLPEALQSLWSLLKSRSC :::::. : :: : ...... .:. : .. : ::::::: .....: ...:: CCDS31 LANKQDMPGALTAEDITRMFKVKKLCSDRNWYVQPCCALTGEGLAQGFRKLTGFVKSHMK 130 140 150 160 170 180 180 190 pF1KB8 MCLQARAHGAERGDSKRS CCDS31 SRGDTLAFFKQN 190 >>CCDS9695.1 ARF6 gene_id:382|Hs108|chr14 (175 aa) initn: 461 init1: 308 opt: 472 Z-score: 549.3 bits: 108.3 E(32554): 2.8e-24 Smith-Waterman score: 472; 44.6% identity (72.3% similar) in 177 aa overlap (1-175:1-175) 10 20 30 40 50 pF1KB8 MGSVNSR--GHKAEAQVVMMGLDSAGKTTLLYKLKGHQLVETLPTVGFNVEPLKAPGHVS ::.: :. :.: : ...:.:::.:::::.::::: : : :.:::::::: . .:. CCDS96 MGKVLSKIFGNK-EMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYK-NVK 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 LTLWDVGGQAPLRASWKDYLEGTDILVYVLDSTDEARLPESAAELTEVLNDPNMAGVPFL ...:::::: .: :. : ::. :..:.: .:. :. :. :: ...:: .: . .: CCDS96 FNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIIL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 VLANKQEAPDALPLLKIRNRLSLERFQDHRWELRGCSALTGEGLPEALQSLWSLLKSRSC ..::::. :::. .:...:.: :..:. : .. : .:.:: :.: : : :: CCDS96 IFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS 120 130 140 150 160 170 180 190 pF1KB8 MCLQARAHGAERGDSKRS >>CCDS7538.1 ARL3 gene_id:403|Hs108|chr10 (182 aa) initn: 440 init1: 341 opt: 466 Z-score: 542.2 bits: 107.0 E(32554): 7e-24 Smith-Waterman score: 466; 42.1% identity (79.2% similar) in 159 aa overlap (12-170:17-172) 10 20 30 40 50 pF1KB8 MGSVNSRGHKAEAQVVMMGLDSAGKTTLLYKLKGHQLVETLPTVGFNVEPLKAPG :......:::.::::::: .: .... . :: :::.. ... : CCDS75 MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 HVSLTLWDVGGQAPLRASWKDYLEGTDILVYVLDSTDEARLPESAAELTEVLNDPNMAGV .:..::.::: .: ::.:.:.::::.::.::.:. :. :.. ::.:.:.. ... : CCDS75 F-KLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCV 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 PFLVLANKQEAPDALPLLKIRNRLSLERFQDHRWELRGCSALTGEGLPEALQSLWSLLKS : :..::::. : : .: . :.:. ..:. :....::::::::. .... : CCDS75 PVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMN--WVCKNV 120 130 140 150 160 170 180 190 pF1KB8 RSCMCLQARAHGAERGDSKRS CCDS75 NAKKK 180 >>CCDS8088.1 ARL2 gene_id:402|Hs108|chr11 (184 aa) initn: 454 init1: 335 opt: 455 Z-score: 529.7 bits: 104.7 E(32554): 3.5e-23 Smith-Waterman score: 455; 42.4% identity (75.2% similar) in 165 aa overlap (12-176:16-179) 10 20 30 40 50 pF1KB8 MGSVNSRGHKAEAQVVMMGLDSAGKTTLLYKLKGHQLVETLPTVGFNVEPLKAPGH : ...:.:::.:::::.: :..:... ::.:::.. :. : CCDS80 MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGF 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 VSLTLWDVGGQAPLRASWKDYLEGTDILVYVLDSTDEARLPESAAELTEVLNDPNMAGVP .:..:::::: ::. :..:.:.:: :..:.::.:. :. . :: .: . .::. CCDS80 -KLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGAT 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 FLVLANKQEAPDALPLLKIRNRLSLERFQDHRWELRGCSALTGEGLPEALQSLWSLLKSR .:..::::. : :: ::. : :. ...:.: ..::::.:::.: ... : . ..:: CCDS80 LLIFANKQDLPGALSSNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSR 120 130 140 150 160 170 180 190 pF1KB8 SCMCLQARAHGAERGDSKRS CCDS80 IFTAD 180 >>CCDS63169.1 ARL4C gene_id:10123|Hs108|chr2 (201 aa) initn: 458 init1: 246 opt: 454 Z-score: 528.0 bits: 104.5 E(32554): 4.3e-23 Smith-Waterman score: 454; 40.9% identity (70.2% similar) in 198 aa overlap (1-190:1-197) 10 20 30 40 50 pF1KB8 MGSVNSRGHKAEA-QVVMMGLDSAGKTTLLYKLKGHQLVETLPTVGFNVEPLK-----AP ::...: .. ..::.:::::::::.::.:: ...:.:.::.:::.: .: : CCDS63 MGNISSNISAFQSLHIVMLGLDSAGKTTVLYRLKFNEFVNTVPTIGFNTEKIKLSNGTAK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 GHVSLTLWDVGGQAPLRASWKDYLEGTDILVYVLDSTDEARLPESAAELTEVLNDPNMAG : .: .:::::: :: ::.: . :: ..::.::.: :: :. .:: .: . . : CCDS63 G-ISCHFWDVGGQEKLRPLWKSYSRCTDGIIYVVDSVDVDRLEEAKTELHKVTKFAENQG 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 VPFLVLANKQEAPDALPLLKIRNRLSL-ERFQDHRWELRGCSALTGEGLPEALQSLWSL- .:.::.::::. : .::. .:...:.: : . .... :. :::: :....:. . CCDS63 TPLLVIANKQDLPKSLPVAEIEKQLALHELIPATTYHVQPACAIIGEGLTEGMDKLYEMI 120 130 140 150 160 170 180 190 pF1KB8 LKSRSCMCLQARAHGAERGDSKRS :: :. . . . : : CCDS63 LKRRKSLKQKKKRTGDLRSCEV 180 190 200 >>CCDS34745.1 ARF5 gene_id:381|Hs108|chr7 (180 aa) initn: 416 init1: 284 opt: 450 Z-score: 524.1 bits: 103.7 E(32554): 7.1e-23 Smith-Waterman score: 450; 40.1% identity (76.6% similar) in 167 aa overlap (10-176:15-180) 10 20 30 40 50 pF1KB8 MGSVNSRGHKAEAQVVMMGLDSAGKTTLLYKLKGHQLVETLPTVGFNVEPLKAPG : . ...:.:::.:::::.::::: ..: :.::.::::: .. CCDS34 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYK- 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 HVSLTLWDVGGQAPLRASWKDYLEGTDILVYVLDSTDEARLPESAAELTEVLNDPNMAGV .. .:.:::::: .: :. :...:. :..:.::.:. :. ::: :: ..:.. .. . CCDS34 NICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 PFLVLANKQEAPDALPLLKIRNRLSLERFQDHRWELRGCSALTGEGLPEALQSLWSLLKS .::.::::. :.:.:. .. ..:.:...... : ... : : :: ..:. : :.. CCDS34 VLLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSK 120 130 140 150 160 170 180 190 pF1KB8 RSCMCLQARAHGAERGDSKRS : CCDS34 R 180 >>CCDS8774.1 ARF3 gene_id:377|Hs108|chr12 (181 aa) initn: 423 init1: 277 opt: 449 Z-score: 522.9 bits: 103.5 E(32554): 8.3e-23 Smith-Waterman score: 449; 40.7% identity (75.4% similar) in 167 aa overlap (10-176:15-180) 10 20 30 40 50 pF1KB8 MGSVNSRGHKAEAQVVMMGLDSAGKTTLLYKLKGHQLVETLPTVGFNVEPLKAPG : : ...:.:::.:::::.::::: ..: :.::.::::: .. CCDS87 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYK- 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 HVSLTLWDVGGQAPLRASWKDYLEGTDILVYVLDSTDEARLPESAAELTEVLNDPNMAGV ..:.:.:::::: .: :. :...:. :..:.::.:. :. :. :: ..: . .. . CCDS87 NISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 PFLVLANKQEAPDALPLLKIRNRLSLERFQDHRWELRGCSALTGEGLPEALQSLWSLLKS .::.::::. :.:. .: ..:.:. .. . : ... : .:.:: :.:. : . ::. CCDS87 VLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKN 120 130 140 150 160 170 180 190 pF1KB8 RSCMCLQARAHGAERGDSKRS . CCDS87 KK 180 >>CCDS2512.1 ARL4C gene_id:10123|Hs108|chr2 (192 aa) initn: 458 init1: 246 opt: 449 Z-score: 522.6 bits: 103.5 E(32554): 8.7e-23 Smith-Waterman score: 449; 42.2% identity (72.2% similar) in 187 aa overlap (1-179:1-186) 10 20 30 40 50 pF1KB8 MGSVNSRGHKAEA-QVVMMGLDSAGKTTLLYKLKGHQLVETLPTVGFNVEPLK-----AP ::...: .. ..::.:::::::::.::.:: ...:.:.::.:::.: .: : CCDS25 MGNISSNISAFQSLHIVMLGLDSAGKTTVLYRLKFNEFVNTVPTIGFNTEKIKLSNGTAK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 GHVSLTLWDVGGQAPLRASWKDYLEGTDILVYVLDSTDEARLPESAAELTEVLNDPNMAG : .: .:::::: :: ::.: . :: ..::.::.: :: :. .:: .: . . : CCDS25 G-ISCHFWDVGGQEKLRPLWKSYSRCTDGIIYVVDSVDVDRLEEAKTELHKVTKFAENQG 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 VPFLVLANKQEAPDALPLLKIRNRLSL-ERFQDHRWELRGCSALTGEGLPEALQSLWSL- .:.::.::::. : .::. .:...:.: : . .... :. :::: :....:. . CCDS25 TPLLVIANKQDLPKSLPVAEIEKQLALHELIPATTYHVQPACAIIGEGLTEGMDKLYEMI 120 130 140 150 160 170 180 190 pF1KB8 LKSRSCMCLQARAHGAERGDSKRS :: :. . CCDS25 LKRRKSLKQKKKR 180 190 >>CCDS1565.1 ARF1 gene_id:375|Hs108|chr1 (181 aa) initn: 412 init1: 266 opt: 443 Z-score: 516.1 bits: 102.2 E(32554): 2e-22 Smith-Waterman score: 443; 40.1% identity (75.4% similar) in 167 aa overlap (10-176:15-180) 10 20 30 40 50 pF1KB8 MGSVNSRGHKAEAQVVMMGLDSAGKTTLLYKLKGHQLVETLPTVGFNVEPLKAPG : : ...:.:::.:::::.::::: ..: :.::.::::: .. CCDS15 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYK- 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 HVSLTLWDVGGQAPLRASWKDYLEGTDILVYVLDSTDEARLPESAAELTEVLNDPNMAGV ..:.:.:::::: .: :. :...:. :..:.::.:. :. :. :: ..: . .. . CCDS15 NISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 PFLVLANKQEAPDALPLLKIRNRLSLERFQDHRWELRGCSALTGEGLPEALQSLWSLLKS .::.::::. :.:. .: ..:.:. .. . : ... : .:.:: :.:. : . :.. CCDS15 VLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRN 120 130 140 150 160 170 180 190 pF1KB8 RSCMCLQARAHGAERGDSKRS . CCDS15 QK 180 196 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:16:04 2016 done: Fri Nov 4 15:16:04 2016 Total Scan time: 1.830 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]