FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8756, 200 aa 1>>>pF1KB8756 200 - 200 aa - 200 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4144+/-0.000982; mu= 13.0334+/- 0.060 mean_var=83.8257+/-17.765, 0's: 0 Z-trim(106.2): 179 B-trim: 737 in 2/48 Lambda= 0.140083 statistics sampled from 8654 (8860) to 8654 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.657), E-opt: 0.2 (0.272), width: 16 Scan time: 1.800 The best scores are: opt bits E(32554) CCDS5359.1 ARL4A gene_id:10124|Hs108|chr7 ( 200) 1305 273.3 7e-74 CCDS2512.1 ARL4C gene_id:10123|Hs108|chr2 ( 192) 921 195.7 1.5e-50 CCDS63169.1 ARL4C gene_id:10123|Hs108|chr2 ( 201) 921 195.7 1.6e-50 CCDS11463.1 ARL4D gene_id:379|Hs108|chr17 ( 201) 819 175.1 2.6e-44 CCDS2884.1 ARF4 gene_id:378|Hs108|chr3 ( 180) 515 113.6 7.4e-26 CCDS8774.1 ARF3 gene_id:377|Hs108|chr12 ( 181) 505 111.6 3e-25 CCDS9695.1 ARF6 gene_id:382|Hs108|chr14 ( 175) 504 111.4 3.4e-25 CCDS34745.1 ARF5 gene_id:381|Hs108|chr7 ( 180) 499 110.4 7e-25 CCDS1565.1 ARF1 gene_id:375|Hs108|chr1 ( 181) 498 110.2 8e-25 CCDS3192.1 ARL14 gene_id:80117|Hs108|chr3 ( 192) 495 109.6 1.3e-24 CCDS7131.1 ARL5B gene_id:221079|Hs108|chr10 ( 179) 453 101.1 4.4e-22 CCDS3987.1 TRIM23 gene_id:373|Hs108|chr5 ( 574) 442 99.3 4.9e-21 CCDS44958.1 ARL1 gene_id:400|Hs108|chr12 ( 181) 427 95.8 1.7e-20 CCDS2195.1 ARL5A gene_id:26225|Hs108|chr2 ( 179) 426 95.6 1.9e-20 CCDS9419.1 ARL11 gene_id:115761|Hs108|chr13 ( 196) 413 93.0 1.3e-19 CCDS43322.1 TRIM23 gene_id:373|Hs108|chr5 ( 569) 410 92.8 4.3e-19 CCDS7538.1 ARL3 gene_id:403|Hs108|chr10 ( 182) 401 90.6 6.4e-19 CCDS2928.1 ARL6 gene_id:84100|Hs108|chr3 ( 186) 387 87.8 4.6e-18 CCDS3986.1 TRIM23 gene_id:373|Hs108|chr5 ( 546) 388 88.3 9.1e-18 CCDS8088.1 ARL2 gene_id:402|Hs108|chr11 ( 184) 364 83.1 1.2e-16 CCDS45664.1 ARL5C gene_id:390790|Hs108|chr17 ( 179) 358 81.9 2.6e-16 CCDS13533.1 ARFRP1 gene_id:10139|Hs108|chr20 ( 201) 348 79.9 1.2e-15 CCDS46425.1 ARL5A gene_id:26225|Hs108|chr2 ( 142) 339 78.0 3.1e-15 CCDS1421.1 ARL8A gene_id:127829|Hs108|chr1 ( 186) 331 76.4 1.2e-14 CCDS2566.1 ARL8B gene_id:55207|Hs108|chr3 ( 186) 325 75.2 2.7e-14 CCDS46630.1 ARFRP1 gene_id:10139|Hs108|chr20 ( 173) 315 73.2 1.1e-13 CCDS2925.1 ARL13B gene_id:200894|Hs108|chr3 ( 428) 297 69.9 2.6e-12 CCDS4400.1 ARL10 gene_id:285598|Hs108|chr5 ( 244) 289 68.0 5.2e-12 CCDS68172.1 ARFRP1 gene_id:10139|Hs108|chr20 ( 154) 284 66.9 7.4e-12 CCDS73510.1 ARL1 gene_id:400|Hs108|chr12 ( 135) 280 66.0 1.2e-11 CCDS73004.1 ARL8A gene_id:127829|Hs108|chr1 ( 147) 275 65.0 2.5e-11 CCDS7298.1 SAR1A gene_id:56681|Hs108|chr10 ( 198) 276 65.3 2.8e-11 CCDS54850.1 ARL15 gene_id:54622|Hs108|chr5 ( 204) 273 64.7 4.3e-11 >>CCDS5359.1 ARL4A gene_id:10124|Hs108|chr7 (200 aa) initn: 1305 init1: 1305 opt: 1305 Z-score: 1439.9 bits: 273.3 E(32554): 7e-74 Smith-Waterman score: 1305; 100.0% identity (100.0% similar) in 200 aa overlap (1-200:1-200) 10 20 30 40 50 60 pF1KB8 MGNGLSDQTSILSNLPSFQSFHIVILGLDCAGKTTVLYRLQFNEFVNTVPTKGFNTEKIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MGNGLSDQTSILSNLPSFQSFHIVILGLDCAGKTTVLYRLQFNEFVNTVPTKGFNTEKIK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKITR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 VTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKITR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPWHLQPTCAIIGDGLKEGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPWHLQPTCAIIGDGLKEGLE 130 140 150 160 170 180 190 200 pF1KB8 KLHDMIIKRRKMLRQQKKKR :::::::::::::::::::: CCDS53 KLHDMIIKRRKMLRQQKKKR 190 200 >>CCDS2512.1 ARL4C gene_id:10123|Hs108|chr2 (192 aa) initn: 918 init1: 918 opt: 921 Z-score: 1020.8 bits: 195.7 E(32554): 1.5e-50 Smith-Waterman score: 921; 69.5% identity (91.6% similar) in 190 aa overlap (10-199:3-192) 10 20 30 40 50 60 pF1KB8 MGNGLSDQTSILSNLPSFQSFHIVILGLDCAGKTTVLYRLQFNEFVNTVPTKGFNTEKIK .: ::. .:::.:::.:::: ::::::::::.:::::::::: :::::::: CCDS25 MGNISSNISAFQSLHIVMLGLDSAGKTTVLYRLKFNEFVNTVPTIGFNTEKIK 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 VTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKITR .. :..: .. ::::::::::::::::::.::::::..:::::::.:.:::::::::.:. CCDS25 LSNGTAKGISCHFWDVGGQEKLRPLWKSYSRCTDGIIYVVDSVDVDRLEEAKTELHKVTK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 ISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPWHLQPTCAIIGDGLKEGLE ..::::.:.:..:::::: .:: ..:::: ::. :: .: .:.::.:::::.:: ::.. CCDS25 FAENQGTPLLVIANKQDLPKSLPVAEIEKQLALHELIPATTYHVQPACAIIGEGLTEGMD 120 130 140 150 160 170 190 200 pF1KB8 KLHDMIIKRRKMLRQQKKKR ::..::.:::: :.:.::. CCDS25 KLYEMILKRRKSLKQKKKR 180 190 >>CCDS63169.1 ARL4C gene_id:10123|Hs108|chr2 (201 aa) initn: 918 init1: 918 opt: 921 Z-score: 1020.5 bits: 195.7 E(32554): 1.6e-50 Smith-Waterman score: 921; 69.5% identity (91.6% similar) in 190 aa overlap (10-199:3-192) 10 20 30 40 50 60 pF1KB8 MGNGLSDQTSILSNLPSFQSFHIVILGLDCAGKTTVLYRLQFNEFVNTVPTKGFNTEKIK .: ::. .:::.:::.:::: ::::::::::.:::::::::: :::::::: CCDS63 MGNISSNISAFQSLHIVMLGLDSAGKTTVLYRLKFNEFVNTVPTIGFNTEKIK 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 VTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKITR .. :..: .. ::::::::::::::::::.::::::..:::::::.:.:::::::::.:. CCDS63 LSNGTAKGISCHFWDVGGQEKLRPLWKSYSRCTDGIIYVVDSVDVDRLEEAKTELHKVTK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 ISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPWHLQPTCAIIGDGLKEGLE ..::::.:.:..:::::: .:: ..:::: ::. :: .: .:.::.:::::.:: ::.. CCDS63 FAENQGTPLLVIANKQDLPKSLPVAEIEKQLALHELIPATTYHVQPACAIIGEGLTEGMD 120 130 140 150 160 170 190 200 pF1KB8 KLHDMIIKRRKMLRQQKKKR ::..::.:::: :.:.::. CCDS63 KLYEMILKRRKSLKQKKKRTGDLRSCEV 180 190 200 >>CCDS11463.1 ARL4D gene_id:379|Hs108|chr17 (201 aa) initn: 818 init1: 800 opt: 819 Z-score: 909.1 bits: 175.1 E(32554): 2.6e-44 Smith-Waterman score: 819; 60.2% identity (86.1% similar) in 201 aa overlap (1-200:1-201) 10 20 30 40 50 pF1KB8 MGNGLSDQTSILSN-LPSFQSFHIVILGLDCAGKTTVLYRLQFNEFVNTVPTKGFNTEKI ::: :.... :. :: ::..:.:..::: ::::..::::.:.:::..::::::::::: CCDS11 MGNHLTEMAPTASSFLPHFQALHVVVIGLDSAGKTSLLYRLKFKEFVQSVPTKGFNTEKI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 KVTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKIT .: ::.:. .::. :::::::::::::.:::: :::.:::::....::.::::.:::.:. CCDS11 RVPLGGSRGITFQVWDVGGQEKLRPLWRSYTRRTDGLVFVVDAAEAERLEEAKVELHRIS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 RISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPWHLQPTCAIIGDGLKEGL : :.:::::::..::::: ..:: .:.:: ::. ::...: :.: :. : ::..:: CCDS11 RASDNQGVPVLVLANKQDQPGALSAAEVEKRLAVRELAAATLTHVQGCSAVDGLGLQQGL 130 140 150 160 170 180 180 190 200 pF1KB8 EKLHDMIIKRRKMLRQQKKKR :.:..::.::.: : ::.: CCDS11 ERLYEMILKRKKAARGGKKRR 190 200 >>CCDS2884.1 ARF4 gene_id:378|Hs108|chr3 (180 aa) initn: 475 init1: 266 opt: 515 Z-score: 577.7 bits: 113.6 E(32554): 7.4e-26 Smith-Waterman score: 515; 44.2% identity (74.6% similar) in 181 aa overlap (9-189:6-180) 10 20 30 40 50 60 pF1KB8 MGNGLSDQTSILSNLPSFQSFHIVILGLDCAGKTTVLYRLQFNEFVNTVPTKGFNTEKIK .:..: : . ....:...::: :::::.::.:...:.:.:.:: :::.: .. CCDS28 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVE 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 VTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKITR :.. : ::::::...::::: : . :.:..::::: : ::..:. ::.:. CCDS28 Y-----KNICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 ISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPWHLQPTCAIIGDGLKEGLE ..: . . .:. :::::: :....::. :.. : . : :..: ::: : :: :::. CCDS28 VDELRDAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNRT-WYVQATCATQGTGLYEGLD 120 130 140 150 160 170 190 200 pF1KB8 KLHDMIIKRRKMLRQQKKKR : . . :: CCDS28 WLSNELSKR 180 >>CCDS8774.1 ARF3 gene_id:377|Hs108|chr12 (181 aa) initn: 462 init1: 274 opt: 505 Z-score: 566.7 bits: 111.6 E(32554): 3e-25 Smith-Waterman score: 505; 42.1% identity (73.7% similar) in 190 aa overlap (1-190:1-181) 10 20 30 40 50 60 pF1KB8 MGNGLSDQTSILSNLPSFQSFHIVILGLDCAGKTTVLYRLQFNEFVNTVPTKGFNTEKIK ::: ... .:..: . . ..:...::: :::::.::.:...:.:.:.:: :::.: .. CCDS87 MGNIFGN---LLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVE 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 VTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKITR :...: ::::::.:.::::. : . :.:..::::: : ::..::. :: .. CCDS87 Y-----KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 ISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPWHLQPTCAIIGDGLKEGLE .: . . .:. :::::: :... .:: :.. : . :..: ::: :::: :::. CCDS87 EDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRN-WYIQATCATSGDGLYEGLD 120 130 140 150 160 170 190 200 pF1KB8 KLHDMIIKRRKMLRQQKKKR : ... ... CCDS87 WLANQLKNKK 180 >>CCDS9695.1 ARF6 gene_id:382|Hs108|chr14 (175 aa) initn: 472 init1: 268 opt: 504 Z-score: 565.8 bits: 111.4 E(32554): 3.4e-25 Smith-Waterman score: 504; 44.8% identity (74.4% similar) in 172 aa overlap (11-182:4-169) 10 20 30 40 50 60 pF1KB8 MGNGLSDQTSILSNLPSFQSFHIVILGLDCAGKTTVLYRLQFNEFVNTVPTKGFNTEKIK .::.. . . ..:..:::: :::::.::.:.... :.:.:: :::.: . CCDS96 MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVT 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 VTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKITR :.: :. ::::::.:.::::. : :.:..:::: .: .:..::. :::.: CCDS96 Y-----KNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIIN 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 ISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPWHLQPTCAIIGDGLKEGLE : . . .:: :::::: .... ::.. :.. .. . . :..::.:: :::: ::: CCDS96 DREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRN-WYVQPSCATSGDGLYEGLT 110 120 130 140 150 160 190 200 pF1KB8 KLHDMIIKRRKMLRQQKKKR : CCDS96 WLTSNYKS 170 >>CCDS34745.1 ARF5 gene_id:381|Hs108|chr7 (180 aa) initn: 464 init1: 259 opt: 499 Z-score: 560.2 bits: 110.4 E(32554): 7e-25 Smith-Waterman score: 499; 42.5% identity (74.0% similar) in 181 aa overlap (9-189:6-180) 10 20 30 40 50 60 pF1KB8 MGNGLSDQTSILSNLPSFQSFHIVILGLDCAGKTTVLYRLQFNEFVNTVPTKGFNTEKIK ....: . . ....:...::: :::::.::.:...:.:.:.:: :::.: .. CCDS34 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVE 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 VTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKITR :.. : ::::::.:.::::. : . :.:..::::: : ::..:. ::.:. . CCDS34 Y-----KNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQ 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 ISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPWHLQPTCAIIGDGLKEGLE .: . . .:. :::::. :.. .::. :.. .: : : :..: ::: : :: .::. CCDS34 EDELRDAVLLVFANKQDMPNAMPVSELTDKLGLQHLRSRT-WYVQATCATQGTGLYDGLD 120 130 140 150 160 170 190 200 pF1KB8 KLHDMIIKRRKMLRQQKKKR : . :: CCDS34 WLSHELSKR 180 >>CCDS1565.1 ARF1 gene_id:375|Hs108|chr1 (181 aa) initn: 460 init1: 274 opt: 498 Z-score: 559.1 bits: 110.2 E(32554): 8e-25 Smith-Waterman score: 498; 42.5% identity (73.7% similar) in 186 aa overlap (1-186:1-177) 10 20 30 40 50 60 pF1KB8 MGNGLSDQTSILSNLPSFQSFHIVILGLDCAGKTTVLYRLQFNEFVNTVPTKGFNTEKIK ::: ... ....: . . ..:...::: :::::.::.:...:.:.:.:: :::.: .. CCDS15 MGNIFAN---LFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVE 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 VTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKITR :...: ::::::.:.::::. : . :.:..::::: : ::..::. :: .. CCDS15 Y-----KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 ISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPWHLQPTCAIIGDGLKEGLE .: . . .:. :::::: :... .:: :.. : . :..: ::: :::: :::. CCDS15 EDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRN-WYIQATCATSGDGLYEGLD 120 130 140 150 160 170 190 200 pF1KB8 KLHDMIIKRRKMLRQQKKKR : ... CCDS15 WLSNQLRNQK 180 >>CCDS3192.1 ARL14 gene_id:80117|Hs108|chr3 (192 aa) initn: 498 init1: 359 opt: 495 Z-score: 555.5 bits: 109.6 E(32554): 1.3e-24 Smith-Waterman score: 495; 40.1% identity (75.8% similar) in 182 aa overlap (10-191:3-180) 10 20 30 40 50 60 pF1KB8 MGNGLSDQTSILSNLPSFQSFHIVILGLDCAGKTTVLYRLQFNEFVNTVPTKGFNTEKIK :. :. :. .. ....:::: :::.:.::.:.. . ..:.:: :::.: :. CCDS31 MGSLGSKNPQTKQAQVLLLGLDSAGKSTLLYKLKLAKDITTIPTIGFNVEMIE 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 VTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKITR . . : :: ::::::::.: .: : . :::.:.::::.: .:.::.. ....: . CCDS31 LERNLSLTV----WDVGGQEKMRTVWGCYCENTDGLVYVVDSTDKQRLEESQRQFEHILK 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 ISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPWHLQPTCAIIGDGLKEGLE . ..:::...:::::. ..:. .: ... . .: :. :..:: ::. :.:: .:.. CCDS31 NEHIKNVPVVLLANKQDMPGALTAEDITRMFKVKKLCSDRNWYVQPCCALTGEGLAQGFR 110 120 130 140 150 160 190 200 pF1KB8 KLHDMIIKRRKMLRQQKKKR :: .. .. : CCDS31 KLTGFVKSHMKSRGDTLAFFKQN 170 180 190 200 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:18:41 2016 done: Fri Nov 4 15:18:42 2016 Total Scan time: 1.800 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]