Result of FASTA (omim) for
pF1KB8762
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8762, 210 aa
1>>>pF1KB8762 210 - 210 aa - 210 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.9348+/-0.000285; mu= 3.6253+/- 0.018
mean_var=174.2284+/-35.385, 0's: 0 Z-trim(123.9): 15 B-trim: 1374 in 1/58
Lambda= 0.097166
statistics sampled from 44610 (44629) to 44610 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.832), E-opt: 0.2 (0.523), width: 16
Scan time: 7.580
The best scores are: opt bits E(85289)
NP_006770 (OMIM: 606132) cdc42 effector protein 2 ( 210) 1428 210.9 1.2e-54
XP_016872583 (OMIM: 606132) PREDICTED: cdc42 effec ( 210) 1428 210.9 1.2e-54
XP_011530784 (OMIM: 606133) PREDICTED: cdc42 effec ( 254) 444 73.0 4.7e-13
NP_006440 (OMIM: 606133) cdc42 effector protein 3 ( 254) 444 73.0 4.7e-13
NP_001257367 (OMIM: 606133) cdc42 effector protein ( 254) 444 73.0 4.7e-13
NP_001257365 (OMIM: 606133) cdc42 effector protein ( 254) 444 73.0 4.7e-13
NP_001257366 (OMIM: 606133) cdc42 effector protein ( 254) 444 73.0 4.7e-13
XP_006724170 (OMIM: 606084) PREDICTED: cdc42 effec ( 391) 284 50.8 3.7e-06
XP_016884030 (OMIM: 606084) PREDICTED: cdc42 effec ( 391) 284 50.8 3.7e-06
XP_006724171 (OMIM: 606084) PREDICTED: cdc42 effec ( 391) 284 50.8 3.7e-06
XP_006724172 (OMIM: 606084) PREDICTED: cdc42 effec ( 391) 284 50.8 3.7e-06
NP_689449 (OMIM: 606084) cdc42 effector protein 1 ( 391) 284 50.8 3.7e-06
>>NP_006770 (OMIM: 606132) cdc42 effector protein 2 [Hom (210 aa)
initn: 1428 init1: 1428 opt: 1428 Z-score: 1102.0 bits: 210.9 E(85289): 1.2e-54
Smith-Waterman score: 1428; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:1-210)
10 20 30 40 50 60
pF1KB8 MSTKVPIYLKRGSRKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGGGSDMFGDISFLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MSTKVPIYLKRGSRKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGGGSDMFGDISFLQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KFHLLPGTMVEGPEEDGTFDLPFQFTRTATVCGRELPDGPSPLLKNAISLPVIGGPQALT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KFHLLPGTMVEGPEEDGTFDLPFQFTRTATVCGRELPDGPSPLLKNAISLPVIGGPQALT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LPTAQAPPKPPRLHLETPQPSPQEGGSVDIWRIPETGSPNSGLTPESGAEEPFLSNASSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LPTAQAPPKPPRLHLETPQPSPQEGGSVDIWRIPETGSPNSGLTPESGAEEPFLSNASSL
130 140 150 160 170 180
190 200 210
pF1KB8 LSLHVDLGPSILDDVLQIMDQDLDSMQIPT
::::::::::::::::::::::::::::::
NP_006 LSLHVDLGPSILDDVLQIMDQDLDSMQIPT
190 200 210
>>XP_016872583 (OMIM: 606132) PREDICTED: cdc42 effector (210 aa)
initn: 1428 init1: 1428 opt: 1428 Z-score: 1102.0 bits: 210.9 E(85289): 1.2e-54
Smith-Waterman score: 1428; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:1-210)
10 20 30 40 50 60
pF1KB8 MSTKVPIYLKRGSRKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGGGSDMFGDISFLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTKVPIYLKRGSRKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGGGSDMFGDISFLQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KFHLLPGTMVEGPEEDGTFDLPFQFTRTATVCGRELPDGPSPLLKNAISLPVIGGPQALT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFHLLPGTMVEGPEEDGTFDLPFQFTRTATVCGRELPDGPSPLLKNAISLPVIGGPQALT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LPTAQAPPKPPRLHLETPQPSPQEGGSVDIWRIPETGSPNSGLTPESGAEEPFLSNASSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPTAQAPPKPPRLHLETPQPSPQEGGSVDIWRIPETGSPNSGLTPESGAEEPFLSNASSL
130 140 150 160 170 180
190 200 210
pF1KB8 LSLHVDLGPSILDDVLQIMDQDLDSMQIPT
::::::::::::::::::::::::::::::
XP_016 LSLHVDLGPSILDDVLQIMDQDLDSMQIPT
190 200 210
>>XP_011530784 (OMIM: 606133) PREDICTED: cdc42 effector (254 aa)
initn: 540 init1: 293 opt: 444 Z-score: 355.4 bits: 73.0 E(85289): 4.7e-13
Smith-Waterman score: 450; 42.9% identity (59.6% similar) in 245 aa overlap (1-192:1-243)
10 20 30 40 50
pF1KB8 MSTKVPIYLKRGS-RKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGGGSDMFGDISFLQ
: .:.::::: .. .:::: ::::.:: :::::::::::::::::. : :.::::::::
XP_011 MPAKTPIYLKAANNKKGKKFKLRDILSPDMISPPLGDFRHTIHIGKEGQHDVFGDISFLQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 GKFHLLPGTMVEGPEEDGTFDLPFQFTRTATVCGRELPDGPSPLLKNAISLPVIGGPQAL
:...::::.. .. . : : .: :. .. . . :::.::::::::.::: :::
XP_011 GNYELLPGNQEKA--HLGQFPGHNEFFRANSTSDSVFTETPSPVLKNAISLPTIGGSQAL
70 80 90 100 110
120 130 140 150
pF1KB8 TLP--------TAQ---APPKPPRLHLET-------PQPSPQEGGSV---DI-WRIPETG
:: . : .: : ::: : . : :.:.: : : ..
XP_011 MLPLLSPVTFNSKQESFGPAKLPRLSCEPVMEEKAQEKSSLLENGTVHQGDTSWGSSGSA
120 130 140 150 160 170
160 170 180
pF1KB8 SPNS--------GLT---PESGAEEPF------------------LSNAS-SLLSLHVDL
: .: .:. :. ::. : ::. . :::::..::
XP_011 SQSSQGRDSHSSSLSEQYPDWPAEDMFDHPTPCELIKGKTKSEESLSDLTGSLLSLQLDL
180 190 200 210 220 230
190 200 210
pF1KB8 GPSILDDVLQIMDQDLDSMQIPT
:::.:
XP_011 GPSLLDEVLNVMDKNK
240 250
>>NP_006440 (OMIM: 606133) cdc42 effector protein 3 [Hom (254 aa)
initn: 540 init1: 293 opt: 444 Z-score: 355.4 bits: 73.0 E(85289): 4.7e-13
Smith-Waterman score: 450; 42.9% identity (59.6% similar) in 245 aa overlap (1-192:1-243)
10 20 30 40 50
pF1KB8 MSTKVPIYLKRGS-RKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGGGSDMFGDISFLQ
: .:.::::: .. .:::: ::::.:: :::::::::::::::::. : :.::::::::
NP_006 MPAKTPIYLKAANNKKGKKFKLRDILSPDMISPPLGDFRHTIHIGKEGQHDVFGDISFLQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 GKFHLLPGTMVEGPEEDGTFDLPFQFTRTATVCGRELPDGPSPLLKNAISLPVIGGPQAL
:...::::.. .. . : : .: :. .. . . :::.::::::::.::: :::
NP_006 GNYELLPGNQEKA--HLGQFPGHNEFFRANSTSDSVFTETPSPVLKNAISLPTIGGSQAL
70 80 90 100 110
120 130 140 150
pF1KB8 TLP--------TAQ---APPKPPRLHLET-------PQPSPQEGGSV---DI-WRIPETG
:: . : .: : ::: : . : :.:.: : : ..
NP_006 MLPLLSPVTFNSKQESFGPAKLPRLSCEPVMEEKAQEKSSLLENGTVHQGDTSWGSSGSA
120 130 140 150 160 170
160 170 180
pF1KB8 SPNS--------GLT---PESGAEEPF------------------LSNAS-SLLSLHVDL
: .: .:. :. ::. : ::. . :::::..::
NP_006 SQSSQGRDSHSSSLSEQYPDWPAEDMFDHPTPCELIKGKTKSEESLSDLTGSLLSLQLDL
180 190 200 210 220 230
190 200 210
pF1KB8 GPSILDDVLQIMDQDLDSMQIPT
:::.:
NP_006 GPSLLDEVLNVMDKNK
240 250
>>NP_001257367 (OMIM: 606133) cdc42 effector protein 3 [ (254 aa)
initn: 540 init1: 293 opt: 444 Z-score: 355.4 bits: 73.0 E(85289): 4.7e-13
Smith-Waterman score: 450; 42.9% identity (59.6% similar) in 245 aa overlap (1-192:1-243)
10 20 30 40 50
pF1KB8 MSTKVPIYLKRGS-RKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGGGSDMFGDISFLQ
: .:.::::: .. .:::: ::::.:: :::::::::::::::::. : :.::::::::
NP_001 MPAKTPIYLKAANNKKGKKFKLRDILSPDMISPPLGDFRHTIHIGKEGQHDVFGDISFLQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 GKFHLLPGTMVEGPEEDGTFDLPFQFTRTATVCGRELPDGPSPLLKNAISLPVIGGPQAL
:...::::.. .. . : : .: :. .. . . :::.::::::::.::: :::
NP_001 GNYELLPGNQEKA--HLGQFPGHNEFFRANSTSDSVFTETPSPVLKNAISLPTIGGSQAL
70 80 90 100 110
120 130 140 150
pF1KB8 TLP--------TAQ---APPKPPRLHLET-------PQPSPQEGGSV---DI-WRIPETG
:: . : .: : ::: : . : :.:.: : : ..
NP_001 MLPLLSPVTFNSKQESFGPAKLPRLSCEPVMEEKAQEKSSLLENGTVHQGDTSWGSSGSA
120 130 140 150 160 170
160 170 180
pF1KB8 SPNS--------GLT---PESGAEEPF------------------LSNAS-SLLSLHVDL
: .: .:. :. ::. : ::. . :::::..::
NP_001 SQSSQGRDSHSSSLSEQYPDWPAEDMFDHPTPCELIKGKTKSEESLSDLTGSLLSLQLDL
180 190 200 210 220 230
190 200 210
pF1KB8 GPSILDDVLQIMDQDLDSMQIPT
:::.:
NP_001 GPSLLDEVLNVMDKNK
240 250
>>NP_001257365 (OMIM: 606133) cdc42 effector protein 3 [ (254 aa)
initn: 540 init1: 293 opt: 444 Z-score: 355.4 bits: 73.0 E(85289): 4.7e-13
Smith-Waterman score: 450; 42.9% identity (59.6% similar) in 245 aa overlap (1-192:1-243)
10 20 30 40 50
pF1KB8 MSTKVPIYLKRGS-RKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGGGSDMFGDISFLQ
: .:.::::: .. .:::: ::::.:: :::::::::::::::::. : :.::::::::
NP_001 MPAKTPIYLKAANNKKGKKFKLRDILSPDMISPPLGDFRHTIHIGKEGQHDVFGDISFLQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 GKFHLLPGTMVEGPEEDGTFDLPFQFTRTATVCGRELPDGPSPLLKNAISLPVIGGPQAL
:...::::.. .. . : : .: :. .. . . :::.::::::::.::: :::
NP_001 GNYELLPGNQEKA--HLGQFPGHNEFFRANSTSDSVFTETPSPVLKNAISLPTIGGSQAL
70 80 90 100 110
120 130 140 150
pF1KB8 TLP--------TAQ---APPKPPRLHLET-------PQPSPQEGGSV---DI-WRIPETG
:: . : .: : ::: : . : :.:.: : : ..
NP_001 MLPLLSPVTFNSKQESFGPAKLPRLSCEPVMEEKAQEKSSLLENGTVHQGDTSWGSSGSA
120 130 140 150 160 170
160 170 180
pF1KB8 SPNS--------GLT---PESGAEEPF------------------LSNAS-SLLSLHVDL
: .: .:. :. ::. : ::. . :::::..::
NP_001 SQSSQGRDSHSSSLSEQYPDWPAEDMFDHPTPCELIKGKTKSEESLSDLTGSLLSLQLDL
180 190 200 210 220 230
190 200 210
pF1KB8 GPSILDDVLQIMDQDLDSMQIPT
:::.:
NP_001 GPSLLDEVLNVMDKNK
240 250
>>NP_001257366 (OMIM: 606133) cdc42 effector protein 3 [ (254 aa)
initn: 540 init1: 293 opt: 444 Z-score: 355.4 bits: 73.0 E(85289): 4.7e-13
Smith-Waterman score: 450; 42.9% identity (59.6% similar) in 245 aa overlap (1-192:1-243)
10 20 30 40 50
pF1KB8 MSTKVPIYLKRGS-RKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGGGSDMFGDISFLQ
: .:.::::: .. .:::: ::::.:: :::::::::::::::::. : :.::::::::
NP_001 MPAKTPIYLKAANNKKGKKFKLRDILSPDMISPPLGDFRHTIHIGKEGQHDVFGDISFLQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 GKFHLLPGTMVEGPEEDGTFDLPFQFTRTATVCGRELPDGPSPLLKNAISLPVIGGPQAL
:...::::.. .. . : : .: :. .. . . :::.::::::::.::: :::
NP_001 GNYELLPGNQEKA--HLGQFPGHNEFFRANSTSDSVFTETPSPVLKNAISLPTIGGSQAL
70 80 90 100 110
120 130 140 150
pF1KB8 TLP--------TAQ---APPKPPRLHLET-------PQPSPQEGGSV---DI-WRIPETG
:: . : .: : ::: : . : :.:.: : : ..
NP_001 MLPLLSPVTFNSKQESFGPAKLPRLSCEPVMEEKAQEKSSLLENGTVHQGDTSWGSSGSA
120 130 140 150 160 170
160 170 180
pF1KB8 SPNS--------GLT---PESGAEEPF------------------LSNAS-SLLSLHVDL
: .: .:. :. ::. : ::. . :::::..::
NP_001 SQSSQGRDSHSSSLSEQYPDWPAEDMFDHPTPCELIKGKTKSEESLSDLTGSLLSLQLDL
180 190 200 210 220 230
190 200 210
pF1KB8 GPSILDDVLQIMDQDLDSMQIPT
:::.:
NP_001 GPSLLDEVLNVMDKNK
240 250
>>XP_006724170 (OMIM: 606084) PREDICTED: cdc42 effector (391 aa)
initn: 299 init1: 131 opt: 284 Z-score: 231.6 bits: 50.8 E(85289): 3.7e-06
Smith-Waterman score: 284; 33.7% identity (59.8% similar) in 199 aa overlap (13-199:26-214)
10 20 30 40
pF1KB8 MSTKVPIYLKRGSRKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGG
: .::.. :..:::: ::::::::.:.: ::
XP_006 MPGPQGGRGAATMSLGKLSPVGWVSSSQGKRR-----LTADMISHPLGDFRHTMHVGRGG
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 GSDMFGDISFLQGKFHLLPGTMVEGPEEDGTFDLPFQFTRTATVCGREL--PDGPSP---
:.::: :::... :. ..:. . . .:..: . . :.. : .:::
XP_006 --DVFGDTSFLSNHGGS-SGSTHRSPR--SFLAKKLQLVRRVGAPPRRMASPPAPSPAPP
60 70 80 90 100 110
110 120 130 140 150
pF1KB8 ----LLKNAISLPVIGGPQALTLPTAQAP-PKPPRLHLETPQPSPQEGGSVDIWRIPETG
..::::::: .. .: ... . : . . ..: : :.:..
XP_006 AISPIIKNAISLPQLNQAAYDSLVVGKLSFDSSPTSSTDGHSSYGLDSGFCTISRLPRSE
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB8 SPNSGLTPESGAEEPFLSNASSLLS--LHVDLGPSILDDVLQIMDQDLDSMQIPT
.:.. : :: : ..:::: : .:::::.:...: .:
XP_006 KPHDRDRDGSFPSEPGLRRSDSLLSFRLDLDLGPSLLSELLGVMSLPEAPAAETPAPAAN
180 190 200 210 220 230
XP_006 PPAPTANPTGPAANPPATTANPPAPAANPSAPAATPTGPAANPPAPAASSTPHGHCPNGV
240 250 260 270 280 290
>>XP_016884030 (OMIM: 606084) PREDICTED: cdc42 effector (391 aa)
initn: 299 init1: 131 opt: 284 Z-score: 231.6 bits: 50.8 E(85289): 3.7e-06
Smith-Waterman score: 284; 33.7% identity (59.8% similar) in 199 aa overlap (13-199:26-214)
10 20 30 40
pF1KB8 MSTKVPIYLKRGSRKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGG
: .::.. :..:::: ::::::::.:.: ::
XP_016 MPGPQGGRGAATMSLGKLSPVGWVSSSQGKRR-----LTADMISHPLGDFRHTMHVGRGG
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 GSDMFGDISFLQGKFHLLPGTMVEGPEEDGTFDLPFQFTRTATVCGREL--PDGPSP---
:.::: :::... :. ..:. . . .:..: . . :.. : .:::
XP_016 --DVFGDTSFLSNHGGS-SGSTHRSPR--SFLAKKLQLVRRVGAPPRRMASPPAPSPAPP
60 70 80 90 100 110
110 120 130 140 150
pF1KB8 ----LLKNAISLPVIGGPQALTLPTAQAP-PKPPRLHLETPQPSPQEGGSVDIWRIPETG
..::::::: .. .: ... . : . . ..: : :.:..
XP_016 AISPIIKNAISLPQLNQAAYDSLVVGKLSFDSSPTSSTDGHSSYGLDSGFCTISRLPRSE
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB8 SPNSGLTPESGAEEPFLSNASSLLS--LHVDLGPSILDDVLQIMDQDLDSMQIPT
.:.. : :: : ..:::: : .:::::.:...: .:
XP_016 KPHDRDRDGSFPSEPGLRRSDSLLSFRLDLDLGPSLLSELLGVMSLPEAPAAETPAPAAN
180 190 200 210 220 230
XP_016 PPAPTANPTGPAANPPATTANPPAPAANPSAPAATPTGPAANPPAPAASSTPHGHCPNGV
240 250 260 270 280 290
>>XP_006724171 (OMIM: 606084) PREDICTED: cdc42 effector (391 aa)
initn: 299 init1: 131 opt: 284 Z-score: 231.6 bits: 50.8 E(85289): 3.7e-06
Smith-Waterman score: 284; 33.7% identity (59.8% similar) in 199 aa overlap (13-199:26-214)
10 20 30 40
pF1KB8 MSTKVPIYLKRGSRKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGG
: .::.. :..:::: ::::::::.:.: ::
XP_006 MPGPQGGRGAATMSLGKLSPVGWVSSSQGKRR-----LTADMISHPLGDFRHTMHVGRGG
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 GSDMFGDISFLQGKFHLLPGTMVEGPEEDGTFDLPFQFTRTATVCGREL--PDGPSP---
:.::: :::... :. ..:. . . .:..: . . :.. : .:::
XP_006 --DVFGDTSFLSNHGGS-SGSTHRSPR--SFLAKKLQLVRRVGAPPRRMASPPAPSPAPP
60 70 80 90 100 110
110 120 130 140 150
pF1KB8 ----LLKNAISLPVIGGPQALTLPTAQAP-PKPPRLHLETPQPSPQEGGSVDIWRIPETG
..::::::: .. .: ... . : . . ..: : :.:..
XP_006 AISPIIKNAISLPQLNQAAYDSLVVGKLSFDSSPTSSTDGHSSYGLDSGFCTISRLPRSE
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB8 SPNSGLTPESGAEEPFLSNASSLLS--LHVDLGPSILDDVLQIMDQDLDSMQIPT
.:.. : :: : ..:::: : .:::::.:...: .:
XP_006 KPHDRDRDGSFPSEPGLRRSDSLLSFRLDLDLGPSLLSELLGVMSLPEAPAAETPAPAAN
180 190 200 210 220 230
XP_006 PPAPTANPTGPAANPPATTANPPAPAANPSAPAATPTGPAANPPAPAASSTPHGHCPNGV
240 250 260 270 280 290
210 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:22:20 2016 done: Fri Nov 4 15:22:21 2016
Total Scan time: 7.580 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]