FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8764, 218 aa 1>>>pF1KB8764 218 - 218 aa - 218 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7513+/-0.000299; mu= 13.9241+/- 0.019 mean_var=105.2884+/-21.252, 0's: 0 Z-trim(120.7): 9 B-trim: 699 in 1/53 Lambda= 0.124992 statistics sampled from 36381 (36392) to 36381 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.773), E-opt: 0.2 (0.427), width: 16 Scan time: 6.940 The best scores are: opt bits E(85289) NP_078784 (OMIM: 615246) zinc finger BED domain-co ( 218) 1510 281.8 6e-76 NP_115743 (OMIM: 615250) zinc finger BED domain-co ( 234) 588 115.6 7.1e-26 NP_001316493 (OMIM: 615250) zinc finger BED domain ( 234) 588 115.6 7.1e-26 >>NP_078784 (OMIM: 615246) zinc finger BED domain-contai (218 aa) initn: 1510 init1: 1510 opt: 1510 Z-score: 1484.5 bits: 281.8 E(85289): 6e-76 Smith-Waterman score: 1510; 100.0% identity (100.0% similar) in 218 aa overlap (1-218:1-218) 10 20 30 40 50 60 pF1KB8 MMRREDEEEEGTMMKAKGDLEMKEEEEISETGELVGPFVSAMPTPMPHNKGTRFSEAWEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 MMRREDEEEEGTMMKAKGDLEMKEEEEISETGELVGPFVSAMPTPMPHNKGTRFSEAWEY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FHLAPARAGHHPNQYATCRLCGRQVSRGPGVNVGTTALWKHLKSMHREELEKSGHGQAGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 FHLAPARAGHHPNQYATCRLCGRQVSRGPGVNVGTTALWKHLKSMHREELEKSGHGQAGQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RQDPRPHGPQLPTGIEGNWGRLLEQVGTMALWASQREKEVLRRERAVEWRERAVEKRERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 RQDPRPHGPQLPTGIEGNWGRLLEQVGTMALWASQREKEVLRRERAVEWRERAVEKRERA 130 140 150 160 170 180 190 200 210 pF1KB8 LEEVERAILEMKWKVRAEKEACQREKELPAAVHPFHFV :::::::::::::::::::::::::::::::::::::: NP_078 LEEVERAILEMKWKVRAEKEACQREKELPAAVHPFHFV 190 200 210 >>NP_115743 (OMIM: 615250) zinc finger BED domain-contai (234 aa) initn: 837 init1: 327 opt: 588 Z-score: 585.5 bits: 115.6 E(85289): 7.1e-26 Smith-Waterman score: 588; 52.7% identity (78.1% similar) in 169 aa overlap (37-203:27-193) 10 20 30 40 50 60 pF1KB8 EEEEGTMMKAKGDLEMKEEEEISETGELVGPFVSAMPTPMPHNK-GTRFSEAWEYFHLAP : .. ::: : .. :. .:::: :::::: NP_115 MRSGEPACTMDQARGLDDAAARGGQCPGLGPAPTPTPPGRLGAPYSEAWGYFHLAP 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 ARAGHHPNQYATCRLCGRQVSRGPGVNVGTTALWKHLKSMHREELEKSGHGQAGQRQD-P .: :: ...:::::::.::.:::: ..::.:::.::.: ::.:::.:: :.. : NP_115 GRPGHPSGHWATCRLCGEQVGRGPGFHAGTSALWRHLRSAHRRELESSGAGSSPPAAPCP 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 RPHGPQLPTGIEGNWGRLLEQVGTMALWASQREKEVLRRERAVEWRERAVEKRERALEEV : :: .. ::.:.:::::.:..:. .:.::.:. ::: ::: :::.:.:.:::.: NP_115 PPPGP--AAAPEGDWARLLEQMGALAVRGSRRERELERRELAVEQGERALERRRRALQEE 120 130 140 150 160 170 190 200 210 pF1KB8 ERAILEMKWKVRAEKEACQREKELPAAVHPFHFV ::: . . ...::.:: : NP_115 ERAAAQARRELQAEREALQARLRDVSRREGALGWAPAAPPPLKDDPEGDRDGCVITKVLL 180 190 200 210 220 230 >>NP_001316493 (OMIM: 615250) zinc finger BED domain-con (234 aa) initn: 837 init1: 327 opt: 588 Z-score: 585.5 bits: 115.6 E(85289): 7.1e-26 Smith-Waterman score: 588; 52.7% identity (78.1% similar) in 169 aa overlap (37-203:27-193) 10 20 30 40 50 60 pF1KB8 EEEEGTMMKAKGDLEMKEEEEISETGELVGPFVSAMPTPMPHNK-GTRFSEAWEYFHLAP : .. ::: : .. :. .:::: :::::: NP_001 MRSGEPACTMDQARGLDDAAARGGQCPGLGPAPTPTPPGRLGAPYSEAWGYFHLAP 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 ARAGHHPNQYATCRLCGRQVSRGPGVNVGTTALWKHLKSMHREELEKSGHGQAGQRQD-P .: :: ...:::::::.::.:::: ..::.:::.::.: ::.:::.:: :.. : NP_001 GRPGHPSGHWATCRLCGEQVGRGPGFHAGTSALWRHLRSAHRRELESSGAGSSPPAAPCP 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 RPHGPQLPTGIEGNWGRLLEQVGTMALWASQREKEVLRRERAVEWRERAVEKRERALEEV : :: .. ::.:.:::::.:..:. .:.::.:. ::: ::: :::.:.:.:::.: NP_001 PPPGP--AAAPEGDWARLLEQMGALAVRGSRRERELERRELAVEQGERALERRRRALQEE 120 130 140 150 160 170 190 200 210 pF1KB8 ERAILEMKWKVRAEKEACQREKELPAAVHPFHFV ::: . . ...::.:: : NP_001 ERAAAQARRELQAEREALQARLRDVSRREGALGWAPAAPPPLKDDPEGDRDGCVITKVLL 180 190 200 210 220 230 218 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:23:54 2016 done: Fri Nov 4 15:23:55 2016 Total Scan time: 6.940 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]