FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8765, 223 aa
  1>>>pF1KB8765 223 - 223 aa - 223 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.4072+/-0.000284; mu= 5.6117+/- 0.018
 mean_var=136.2840+/-27.528, 0's: 0 Z-trim(122.7): 2  B-trim: 702 in 1/59
 Lambda= 0.109863
 statistics sampled from 41258 (41260) to 41258 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.484), width:  16
 Scan time:  6.950

The best scores are:                                      opt bits E(85289)
NP_114156 (OMIM: 607713) fibroblast growth factor- ( 223) 1584 261.3 9.3e-70
NP_005121 (OMIM: 607737) fibroblast growth factor- ( 234)  215 44.3  0.0002


>>NP_114156 (OMIM: 607713) fibroblast growth factor-bind  (223 aa)
 initn: 1584 init1: 1584 opt: 1584  Z-score: 1373.4  bits: 261.3 E(85289): 9.3e-70
Smith-Waterman score: 1584; 99.6% identity (99.6% similar) in 223 aa overlap (1-223:1-223)

               10        20        30        40        50        60
pF1KB8 MKFVPCLLLVTLSCLGTLGQAPRQKQGSTGEEFHFQTGGRDSCTMRPSSLGQGAGEVWLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 MKFVPCLLLVTLSCLGTLGQAPRQKQGSTGEEFHFQTGGRDSCTMRPSSLGQGAGEVWLR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 VDCRNTDQTYWCEYRGQPSMCQAFAADPKSYWNQALQELRRLHHACQGAPVLRPSVCREA
       ::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
NP_114 VDCRNTDQTYWCEYRGQPSMCQAFAADPKPYWNQALQELRRLHHACQGAPVLRPSVCREA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 GPQAHMQQVTSSLKGSPEPNQQPEAGTPSLRPKATVKLTEATQLGKDSMEELGKAKPTTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 GPQAHMQQVTSSLKGSPEPNQQPEAGTPSLRPKATVKLTEATQLGKDSMEELGKAKPTTR
              130       140       150       160       170       180

              190       200       210       220   
pF1KB8 PTAKPTQPGPRPGGNEEAKKKAWEHCWKPFQALCAFLISFFRG
       :::::::::::::::::::::::::::::::::::::::::::
NP_114 PTAKPTQPGPRPGGNEEAKKKAWEHCWKPFQALCAFLISFFRG
              190       200       210       220   

>>NP_005121 (OMIM: 607737) fibroblast growth factor-bind  (234 aa)
 initn:  74 init1:  58 opt: 215  Z-score: 200.4  bits: 44.3 E(85289): 0.0002
Smith-Waterman score: 243; 24.0% identity (54.9% similar) in 204 aa overlap (17-219:42-227)

                             10        20        30        40      
pF1KB8               MKFVPCLLLVTLSCLGTLGQAPRQKQGSTGEEFHFQTGGRDSCTMR
                                     :::..  ....  :.. .: :  . .:  :
NP_005 LLLAAQVLLVEGKKKVKNGLHSKVVSEQKDTLGNTQIKQKSRPGNKGKFVTKDQANC--R
              20        30        40        50        60           

         50        60        70        80        90       100      
pF1KB8 PSSLGQGAGEVWLRVDCRNTDQTYWCEYRGQPSMCQAFAADPKSYWNQALQELRRLHHAC
        ..  :  : . :.:.: . :. . : . :.:. :  .  : . ::.:. ..::  .  :
NP_005 WAATEQEEG-ISLKVECTQLDHEFSCVFAGNPTSCLKLK-DERVYWKQVARNLRSQKDIC
      70         80        90       100        110       120       

         110       120       130       140       150       160     
pF1KB8 Q-GAPVLRPSVCREAGPQAHMQQVTSSLKGSPEPNQQPEAGTPSLRPKATVKLTEATQLG
       . .  ...  :::.  :.. .. :.:.: :. .: ..       . :.  .:  :.:  .
NP_005 RYSKTAVKTRVCRKDFPESSLKLVSSTLFGNTKPRKEKT----EMSPREHIKGKETTPSS
       130       140       150       160           170       180   

         170       180       190       200       210       220     
pF1KB8 KDSMEELGKAKPTTRPTAKPTQPGPRPGGNEEAKKKAWEHCWKPFQALCAFLISFFRG  
           . ..   :    .  : . . :        : : : : . ...::.:..:      
NP_005 LAVTQTMATKAPEC--VEDPDMANQR--------KTALEFCGETWSSLCTFFLSIVQDTS
           190         200               210       220       230   

NP_005 C
        




223 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 09:39:22 2016 done: Sat Nov  5 09:39:23 2016
 Total Scan time:  6.950 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]