FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8766, 225 aa 1>>>pF1KB8766 225 - 225 aa - 225 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5808+/-0.00101; mu= 12.4238+/- 0.061 mean_var=71.1667+/-14.813, 0's: 0 Z-trim(104.5): 47 B-trim: 0 in 0/48 Lambda= 0.152032 statistics sampled from 7887 (7931) to 7887 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.244), width: 16 Scan time: 2.050 The best scores are: opt bits E(32554) CCDS60908.1 KCTD14 gene_id:65987|Hs108|chr11 ( 225) 1493 336.6 7.7e-93 CCDS8255.2 KCTD14 gene_id:65987|Hs108|chr11 ( 255) 1493 336.6 8.6e-93 CCDS55117.1 KCTD7 gene_id:154881|Hs108|chr7 ( 288) 376 91.7 5.4e-19 CCDS5534.1 KCTD7 gene_id:154881|Hs108|chr7 ( 289) 376 91.7 5.4e-19 CCDS2891.1 KCTD6 gene_id:200845|Hs108|chr3 ( 237) 264 67.1 1.1e-11 CCDS31645.1 KCTD21 gene_id:283219|Hs108|chr11 ( 260) 254 64.9 5.6e-11 >>CCDS60908.1 KCTD14 gene_id:65987|Hs108|chr11 (225 aa) initn: 1493 init1: 1493 opt: 1493 Z-score: 1780.2 bits: 336.6 E(32554): 7.7e-93 Smith-Waterman score: 1493; 100.0% identity (100.0% similar) in 225 aa overlap (1-225:1-225) 10 20 30 40 50 60 pF1KB8 MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DYLRTGQVPTQHIPEVYREAQFYEIKPLVKLLEDMPQIFGEQVSRKQFLLQVPGYSENLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 DYLRTGQVPTQHIPEVYREAQFYEIKPLVKLLEDMPQIFGEQVSRKQFLLQVPGYSENLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LMVRLARAEAITARKSSVLVCLVETEEQDAYYSEVLCFLQDKKMFKSVVKFGPWKAVLDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LMVRLARAEAITARKSSVLVCLVETEEQDAYYSEVLCFLQDKKMFKSVVKFGPWKAVLDN 130 140 150 160 170 180 190 200 210 220 pF1KB8 SDLMHCLEMDIKAQGYKVFSKFYLTYPTKRNEFHFNIYSFTFTWW ::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SDLMHCLEMDIKAQGYKVFSKFYLTYPTKRNEFHFNIYSFTFTWW 190 200 210 220 >>CCDS8255.2 KCTD14 gene_id:65987|Hs108|chr11 (255 aa) initn: 1493 init1: 1493 opt: 1493 Z-score: 1779.4 bits: 336.6 E(32554): 8.6e-93 Smith-Waterman score: 1493; 100.0% identity (100.0% similar) in 225 aa overlap (1-225:31-255) 10 20 30 pF1KB8 MSTVVELNVGGEFHTTTLGTLRKFPGSKLA :::::::::::::::::::::::::::::: CCDS82 MWQGCAVERPVGRMTSQTPLPQSPRPRRPTMSTVVELNVGGEFHTTTLGTLRKFPGSKLA 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 EMFSSLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQVPTQHIPEVYREAQFYEIKPLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 EMFSSLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQVPTQHIPEVYREAQFYEIKPLVK 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 LLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQDA 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB8 YYSEVLCFLQDKKMFKSVVKFGPWKAVLDNSDLMHCLEMDIKAQGYKVFSKFYLTYPTKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 YYSEVLCFLQDKKMFKSVVKFGPWKAVLDNSDLMHCLEMDIKAQGYKVFSKFYLTYPTKR 190 200 210 220 230 240 220 pF1KB8 NEFHFNIYSFTFTWW ::::::::::::::: CCDS82 NEFHFNIYSFTFTWW 250 >>CCDS55117.1 KCTD7 gene_id:154881|Hs108|chr7 (288 aa) initn: 503 init1: 249 opt: 376 Z-score: 454.5 bits: 91.7 E(32554): 5.4e-19 Smith-Waterman score: 481; 39.1% identity (63.4% similar) in 238 aa overlap (4-224:52-288) 10 20 30 pF1KB8 MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMF :: ::.:: :: :.::: . . :: :: CCDS55 DAEDDFLEPATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMF 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB8 SSLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQVPT-QHIPEVYREAQFYEIKPLVKLL :. ::.:::.:::: .:.: .:..::.:..: ... ::.:::.: : ::.. : CCDS55 SGRHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDLPPRERVRAVYKEAQYYAIGPLLEQL 90 100 110 120 130 140 100 110 120 130 140 pF1KB8 EDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAIT--ARKSSVLVCLVETEEQ-D :.: . ::.: :. :: .: :...:: .:..:: .:. :: ... ::. . : CCDS55 ENMQPLKGEKV-RQAFLGLMPYYKDHLERIVEIARLRAVQRKARFAKLKVCVFKEEMPIT 150 160 170 180 190 200 150 160 170 180 190 pF1KB8 AYYSEVLCFLQ------DKKMFKSV----VKFGPWKAVLDNSDLMHCLEMDIKAQGYKVF : .: :. : ..:. :.::::.:: : ::.::: :..::: : CCDS55 PYECPLLNSLRFERSESDGQLFEHHCEVDVSFGPWEAVADVYDLLHCLVTDLSAQGLTVD 210 220 230 240 250 260 200 210 220 pF1KB8 SKFYLTYPTKR-NEFHFN--IYSFTFTWW . . . :... . :: : .:: CCDS55 HQCIGVCDKHLVNHYYCKRPIYEFKITW 270 280 >>CCDS5534.1 KCTD7 gene_id:154881|Hs108|chr7 (289 aa) initn: 518 init1: 249 opt: 376 Z-score: 454.5 bits: 91.7 E(32554): 5.4e-19 Smith-Waterman score: 496; 39.3% identity (63.6% similar) in 239 aa overlap (4-225:52-289) 10 20 30 pF1KB8 MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMF :: ::.:: :: :.::: . . :: :: CCDS55 DAEDDFLEPATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMF 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB8 SSLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQVPT-QHIPEVYREAQFYEIKPLVKLL :. ::.:::.:::: .:.: .:..::.:..: ... ::.:::.: : ::.. : CCDS55 SGRHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDLPPRERVRAVYKEAQYYAIGPLLEQL 90 100 110 120 130 140 100 110 120 130 140 pF1KB8 EDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAIT--ARKSSVLVCLVETEEQ-D :.: . ::.: :. :: .: :...:: .:..:: .:. :: ... ::. . : CCDS55 ENMQPLKGEKV-RQAFLGLMPYYKDHLERIVEIARLRAVQRKARFAKLKVCVFKEEMPIT 150 160 170 180 190 200 150 160 170 180 190 pF1KB8 AYYSEVLCFLQ------DKKMFKSV----VKFGPWKAVLDNSDLMHCLEMDIKAQGYKVF : .: :. : ..:. :.::::.:: : ::.::: :..::: : CCDS55 PYECPLLNSLRFERSESDGQLFEHHCEVDVSFGPWEAVADVYDLLHCLVTDLSAQGLTVD 210 220 230 240 250 260 200 210 220 pF1KB8 SKFYLTYPTKR-NEFHFN--IYSFTFTWW . . . :... . :: : .::: CCDS55 HQCIGVCDKHLVNHYYCKRPIYEFKITWW 270 280 >>CCDS2891.1 KCTD6 gene_id:200845|Hs108|chr3 (237 aa) initn: 244 init1: 191 opt: 264 Z-score: 323.1 bits: 67.1 E(32554): 1.1e-11 Smith-Waterman score: 264; 29.1% identity (59.2% similar) in 206 aa overlap (1-198:10-205) 10 20 30 40 50 pF1KB8 MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDR :. : :::::...::.: :: ..: : :. ::.. .. : .: .:::: CCDS28 MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDR 10 20 30 40 50 60 60 70 80 90 100 pF1KB8 PSTYFRPILDYLRTGQV--PT--QHIPEVYREAQFYEIKPLVKLLED----MPQIFGEQV . :: .:..:::... : ... . .::.::.:.::.. :.: .:. :.: CCDS28 DGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEV 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 SRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQDAYYSEVLCFLQDKK . . .. ::. . ... .::.. :.: : . :... ..: . CCDS28 VELSSTRKLSKYSNPVAVIITQL---TITTKVHSLL------EGISNYFTKWNKHMMDTR 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 MFKSVVKFGPWKAVLDNSDLMHCLEMDIKAQGYKVFSKFYLTYPTKRNEFHFNIYSFTFT . ::: . : .: .:. : ::. . CCDS28 DCQVSFTFGPCDYHQEVSLRVHLMEY-ITKQGFTIRNTRVHHMSERANENTVEHNWTFCR 180 190 200 210 220 230 pF1KB8 WW CCDS28 LARKTDD >>CCDS31645.1 KCTD21 gene_id:283219|Hs108|chr11 (260 aa) initn: 255 init1: 200 opt: 254 Z-score: 310.6 bits: 64.9 E(32554): 5.6e-11 Smith-Waterman score: 254; 42.9% identity (73.5% similar) in 98 aa overlap (1-94:1-98) 10 20 30 40 50 60 pF1KB8 MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPIL :: . :::::...::.:.:: .:: : :. :::. .. :..: :::: . :: :: CCDS31 MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYIL 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 DYLRTGQV--PT--QHIPEVYREAQFYEIKPLVKLLEDMPQIFGEQVSRKQFLLQVPGYS ..:::... : :.. . :::.::...::.. :.. CCDS31 NFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAEKNAMLNITLNQRV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 ENLELMVRLARAEAITARKSSVLVCLVETEEQDAYYSEVLCFLQDKKMFKSVVKFGPWKA CCDS31 QTVHFTVREAPQIYSLSSSSMEVFNANIFSTSCLFLKLLGSKLFYCSNGNLSSITSHLQD 130 140 150 160 170 180 225 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:24:27 2016 done: Fri Nov 4 15:24:28 2016 Total Scan time: 2.050 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]