FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8770, 234 aa
  1>>>pF1KB8770 234 - 234 aa - 234 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0664+/-0.000344; mu= 10.4076+/- 0.022
 mean_var=76.8117+/-15.645, 0's: 0 Z-trim(114.6): 6  B-trim: 305 in 1/52
 Lambda= 0.146339
 statistics sampled from 24480 (24486) to 24480 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.287), width:  16
 Scan time:  6.740

The best scores are:                                      opt bits E(85289)
NP_005121 (OMIM: 607737) fibroblast growth factor- ( 234) 1548 336.0 3.3e-92
NP_114156 (OMIM: 607713) fibroblast growth factor- ( 223)  214 54.4 1.9e-07


>>NP_005121 (OMIM: 607737) fibroblast growth factor-bind  (234 aa)
 initn: 1548 init1: 1548 opt: 1548  Z-score: 1776.4  bits: 336.0 E(85289): 3.3e-92
Smith-Waterman score: 1548; 100.0% identity (100.0% similar) in 234 aa overlap (1-234:1-234)

               10        20        30        40        50        60
pF1KB8 MKICSLTLLSFLLLAAQVLLVEGKKKVKNGLHSKVVSEQKDTLGNTQIKQKSRPGNKGKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MKICSLTLLSFLLLAAQVLLVEGKKKVKNGLHSKVVSEQKDTLGNTQIKQKSRPGNKGKF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 VTKDQANCRWAATEQEEGISLKVECTQLDHEFSCVFAGNPTSCLKLKDERVYWKQVARNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VTKDQANCRWAATEQEEGISLKVECTQLDHEFSCVFAGNPTSCLKLKDERVYWKQVARNL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RSQKDICRYSKTAVKTRVCRKDFPESSLKLVSSTLFGNTKPRKEKTEMSPREHIKGKETT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RSQKDICRYSKTAVKTRVCRKDFPESSLKLVSSTLFGNTKPRKEKTEMSPREHIKGKETT
              130       140       150       160       170       180

              190       200       210       220       230    
pF1KB8 PSSLAVTQTMATKAPECVEDPDMANQRKTALEFCGETWSSLCTFFLSIVQDTSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PSSLAVTQTMATKAPECVEDPDMANQRKTALEFCGETWSSLCTFFLSIVQDTSC
              190       200       210       220       230    

>>NP_114156 (OMIM: 607713) fibroblast growth factor-bind  (223 aa)
 initn:  73 init1:  57 opt: 214  Z-score: 254.6  bits: 54.4 E(85289): 1.9e-07
Smith-Waterman score: 242; 24.0% identity (54.9% similar) in 204 aa overlap (42-227:17-219)

              20        30        40        50        60           
pF1KB8 LLLAAQVLLVEGKKKVKNGLHSKVVSEQKDTLGNTQIKQKSRPGNKGKFVTKDQANC--R
                                     :::..  ....  :.. .: :  . .:  :
NP_114               MKFVPCLLLVTLSCLGTLGQAPRQKQGSTGEEFHFQTGGRDSCTMR
                             10        20        30        40      

      70         80        90       100        110       120       
pF1KB8 WAATEQEEG-ISLKVECTQLDHEFSCVFAGNPTSCLKLK-DERVYWKQVARNLRSQKDIC
        ..  :  : . :.:.: . :. . : . :.:. :  .  : . ::.:. ..::  .  :
NP_114 PSSLGQGAGEVWLRVDCRNTDQTYWCEYRGQPSMCQAFAADPKPYWNQALQELRRLHHAC
         50        60        70        80        90       100      

       130       140       150       160           170       180   
pF1KB8 RYSKTAVKTRVCRKDFPESSLKLVSSTLFGNTKPRKEKTE----MSPREHIKGKETTPSS
       . .  ...  :::.  :.. .. :.:.: :. .: ..       . :.  .:  :.:  .
NP_114 Q-GAPVLRPSVCREAGPQAHMQQVTSSLKGSPEPNQQPEAGTPSLRPKATVKLTEATQLG
         110       120       130       140       150       160     

           190         200               210       220       230   
pF1KB8 LAVTQTMATKAPEC--VEDPDMANQR--------KTALEFCGETWSSLCTFFLSIVQDTS
           . ..   :    .  : . . :        : : : : . ...::.:..:      
NP_114 KDSMEELGKAKPTTRPTAKPTQPGPRPGGNEEAKKKAWEHCWKPFQALCAFLISFFRG  
         170       180       190       200       210       220     

        
pF1KB8 C




234 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 15:26:23 2016 done: Fri Nov  4 15:26:24 2016
 Total Scan time:  6.740 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]