FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8771, 234 aa 1>>>pF1KB8771 234 - 234 aa - 234 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.3599+/-0.000275; mu= 4.1199+/- 0.017 mean_var=213.9714+/-43.955, 0's: 0 Z-trim(127.2): 3 B-trim: 2251 in 2/57 Lambda= 0.087679 statistics sampled from 54892 (54897) to 54892 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.873), E-opt: 0.2 (0.644), width: 16 Scan time: 8.470 The best scores are: opt bits E(85289) NP_115743 (OMIM: 615250) zinc finger BED domain-co ( 234) 1663 221.3 1.1e-57 NP_001316493 (OMIM: 615250) zinc finger BED domain ( 234) 1663 221.3 1.1e-57 NP_078784 (OMIM: 615246) zinc finger BED domain-co ( 218) 588 85.3 9.3e-17 >>NP_115743 (OMIM: 615250) zinc finger BED domain-contai (234 aa) initn: 1663 init1: 1663 opt: 1663 Z-score: 1156.3 bits: 221.3 E(85289): 1.1e-57 Smith-Waterman score: 1663; 100.0% identity (100.0% similar) in 234 aa overlap (1-234:1-234) 10 20 30 40 50 60 pF1KB8 MRSGEPACTMDQARGLDDAAARGGQCPGLGPAPTPTPPGRLGAPYSEAWGYFHLAPGRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 MRSGEPACTMDQARGLDDAAARGGQCPGLGPAPTPTPPGRLGAPYSEAWGYFHLAPGRPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HPSGHWATCRLCGEQVGRGPGFHAGTSALWRHLRSAHRRELESSGAGSSPPAAPCPPPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 HPSGHWATCRLCGEQVGRGPGFHAGTSALWRHLRSAHRRELESSGAGSSPPAAPCPPPPG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PAAAPEGDWARLLEQMGALAVRGSRRERELERRELAVEQGERALERRRRALQEEERAAAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 PAAAPEGDWARLLEQMGALAVRGSRRERELERRELAVEQGERALERRRRALQEEERAAAQ 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 ARRELQAEREALQARLRDVSRREGALGWAPAAPPPLKDDPEGDRDGCVITKVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 ARRELQAEREALQARLRDVSRREGALGWAPAAPPPLKDDPEGDRDGCVITKVLL 190 200 210 220 230 >>NP_001316493 (OMIM: 615250) zinc finger BED domain-con (234 aa) initn: 1663 init1: 1663 opt: 1663 Z-score: 1156.3 bits: 221.3 E(85289): 1.1e-57 Smith-Waterman score: 1663; 100.0% identity (100.0% similar) in 234 aa overlap (1-234:1-234) 10 20 30 40 50 60 pF1KB8 MRSGEPACTMDQARGLDDAAARGGQCPGLGPAPTPTPPGRLGAPYSEAWGYFHLAPGRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRSGEPACTMDQARGLDDAAARGGQCPGLGPAPTPTPPGRLGAPYSEAWGYFHLAPGRPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HPSGHWATCRLCGEQVGRGPGFHAGTSALWRHLRSAHRRELESSGAGSSPPAAPCPPPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPSGHWATCRLCGEQVGRGPGFHAGTSALWRHLRSAHRRELESSGAGSSPPAAPCPPPPG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PAAAPEGDWARLLEQMGALAVRGSRRERELERRELAVEQGERALERRRRALQEEERAAAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAAAPEGDWARLLEQMGALAVRGSRRERELERRELAVEQGERALERRRRALQEEERAAAQ 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 ARRELQAEREALQARLRDVSRREGALGWAPAAPPPLKDDPEGDRDGCVITKVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARRELQAEREALQARLRDVSRREGALGWAPAAPPPLKDDPEGDRDGCVITKVLL 190 200 210 220 230 >>NP_078784 (OMIM: 615246) zinc finger BED domain-contai (218 aa) initn: 727 init1: 327 opt: 588 Z-score: 421.8 bits: 85.3 E(85289): 9.3e-17 Smith-Waterman score: 588; 52.7% identity (78.1% similar) in 169 aa overlap (27-193:37-203) 10 20 30 40 50 pF1KB8 MRSGEPACTMDQARGLDDAAARGGQCPGLGPAPTPTPPGRLGAPYSEAWGYFHLAP : .. ::: : .. :. .:::: :::::: NP_078 EEEEGTMMKAKGDLEMKEEEEISETGELVGPFVSAMPTPMPHNK-GTRFSEAWEYFHLAP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 GRPGHPSGHWATCRLCGEQVGRGPGFHAGTSALWRHLRSAHRRELESSGAGSSPPAAPCP .: :: ...:::::::.::.:::: ..::.:::.::.: ::.:::.:: :.. : NP_078 ARAGHHPNQYATCRLCGRQVSRGPGVNVGTTALWKHLKSMHREELEKSGHGQAGQRQD-P 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 PPPGPA--AAPEGDWARLLEQMGALAVRGSRRERELERRELAVEQGERALERRRRALQEE : :: .. ::.:.:::::.:..:. .:.::.:. ::: ::: :::.:.:.:::.: NP_078 RPHGPQLPTGIEGNWGRLLEQVGTMALWASQREKEVLRRERAVEWRERAVEKRERALEEV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 ERAAAQARRELQAEREALQARLRDVSRREGALGWAPAAPPPLKDDPEGDRDGCVITKVLL ::: . . ...::.:: : NP_078 ERAILEMKWKVRAEKEACQREKELPAAVHPFHFV 190 200 210 234 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:27:32 2016 done: Fri Nov 4 15:27:34 2016 Total Scan time: 8.470 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]