FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8777, 257 aa 1>>>pF1KB8777 257 - 257 aa - 257 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1519+/-0.000717; mu= 15.8556+/- 0.043 mean_var=83.7308+/-16.857, 0's: 0 Z-trim(111.4): 138 B-trim: 86 in 1/51 Lambda= 0.140162 statistics sampled from 12210 (12385) to 12210 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.758), E-opt: 0.2 (0.38), width: 16 Scan time: 2.350 The best scores are: opt bits E(32554) CCDS13711.1 LRRC3 gene_id:81543|Hs108|chr21 ( 257) 1754 363.9 6e-101 CCDS2644.1 LRRC3B gene_id:116135|Hs108|chr3 ( 259) 797 170.4 1.1e-42 CCDS54121.1 LRRC3C gene_id:100505591|Hs108|chr17 ( 275) 583 127.2 1.2e-29 >>CCDS13711.1 LRRC3 gene_id:81543|Hs108|chr21 (257 aa) initn: 1754 init1: 1754 opt: 1754 Z-score: 1925.8 bits: 363.9 E(32554): 6e-101 Smith-Waterman score: 1754; 100.0% identity (100.0% similar) in 257 aa overlap (1-257:1-257) 10 20 30 40 50 60 pF1KB8 MGTVRPPRPSLLLVSTRESCLFLLFCLHLGAACPQPCRCPDHAGAVAVFCSLRGLQEVPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MGTVRPPRPSLLLVSTRESCLFLLFCLHLGAACPQPCRCPDHAGAVAVFCSLRGLQEVPE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DIPANTVLLKLDANKISHLPDGAFQHLHRLRELDLSHNAIEAIGSATFAGLAGGLRLLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 DIPANTVLLKLDANKISHLPDGAFQHLHRLRELDLSHNAIEAIGSATFAGLAGGLRLLDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SYNRIQRIPKDALGKLSAKIRLSHNPLHCECALQEALWELKLDPDSVDEIACHTSVQEEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SYNRIQRIPKDALGKLSAKIRLSHNPLHCECALQEALWELKLDPDSVDEIACHTSVQEEF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VGKPLVQALDAGASLCSVPHRTTDVAMLVTMFGWFAMVIAYVVYYVRHNQEDARRHLEYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VGKPLVQALDAGASLCSVPHRTTDVAMLVTMFGWFAMVIAYVVYYVRHNQEDARRHLEYL 190 200 210 220 230 240 250 pF1KB8 KSLPSAPASKDPIGPGP ::::::::::::::::: CCDS13 KSLPSAPASKDPIGPGP 250 >>CCDS2644.1 LRRC3B gene_id:116135|Hs108|chr3 (259 aa) initn: 784 init1: 421 opt: 797 Z-score: 879.9 bits: 170.4 E(32554): 1.1e-42 Smith-Waterman score: 797; 48.3% identity (78.1% similar) in 242 aa overlap (10-251:11-250) 10 20 30 40 50 pF1KB8 MGTVRPPRPSLLLVSTRESCLFLLFCLHLGAACPQPCRCPDHAGAVAVFCSLRGLQEVP :: . .: .....:.: .. ::. : : . .:.. : :: .:.:.: CCDS26 MNLVDLWLTRSLSMCLLLQSFVLMILCFHSASMCPKGCLC-SSSGGLNVTCSNANLKEIP 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 EDIPANTVLLKLDANKISHLPDGAFQHLHRLRELDLSHNAIEAIGSATFAGLAGGLRLLD .:.: .:::: ::.:.:. .:. :. ::.:: :.::.:.:: : .: :.: :. :: CCDS26 RDLPPETVLLYLDSNQITSIPNEIFKDLHQLRVLNLSKNGIEFIDEHAFKGVAETLQTLD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 LSYNRIQRIPKDALGKLSAKIRLSHNPLHCECALQEALWELKLDPDSVDEIACHTSVQEE :: :::: . :.:...:.:. :...:: ::.:.::..: . . ... .. :.::: .: CCDS26 LSDNRIQSVHKNAFNNLKARARIANNPWHCDCTLQQVLRSMASNHETAHNVICKTSVLDE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 FVGKPLVQALDAGASLCSVPHRTTDVAMLVTMFGWFAMVIAYVVYYVRHNQEDARRHLEY .:.:...: . :.::..:..::: ::::::::::.:::.:::::::.::::::::::: CCDS26 HAGRPFLNAAN-DADLCNLPKKTTDYAMLVTMFGWFTMVISYVVYYVRQNQEDARRHLEY 180 190 200 210 220 230 240 250 pF1KB8 LKSLPSAPASKDPIGPGP :::::: . : CCDS26 LKSLPSRQKKADEPDDISTVV 240 250 >>CCDS54121.1 LRRC3C gene_id:100505591|Hs108|chr17 (275 aa) initn: 579 init1: 436 opt: 583 Z-score: 645.7 bits: 127.2 E(32554): 1.2e-29 Smith-Waterman score: 583; 40.8% identity (66.5% similar) in 245 aa overlap (11-244:20-262) 10 20 30 40 pF1KB8 MGTVRPPRPSLLLVSTRESCLFLLFCLHLGAACPQP------CRCPDHAGA . .. : : ::. . :.. :.: : .:: CCDS54 MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 VAVFCSLRGLQEVPEDIPANTVLLKLDANKISHLPDGAFQHLHRLRELDLSHNAIEAIGS . :: ::. :: :: .: : ::::... .: :::::: :.::::::::. ... CCDS54 RTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 ATFAGLAGGLRLLDLSYNRIQRIPKDALGKLSAKIRLSHNPLHCECALQEALWELKLDPD :.: :: : :: :::: :.. .: .:. :. .. :: :: ::.:::::.: ...: : CCDS54 AAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPG 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 SVDEIACHTSVQEEFVGKPLVQALDAGAS-LCSV----PHRTTDVAMLVTMFGWFAMVIA . :.: .... ..::. .. : :: ::. .:.::::.:::: ::.....: CCDS54 TGTGIVCGSGARPDLVGQEFL--LLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVA 190 200 210 220 230 230 240 250 pF1KB8 YVVYYVRHNQEDARRHLEYLKSLPSAPASKDPIGPGP :.:.:: .:....:: :. :: CCDS54 YLVHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV 240 250 260 270 257 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:30:32 2016 done: Fri Nov 4 15:30:32 2016 Total Scan time: 2.350 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]