Result of FASTA (omim) for
pF1KB8782
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8782, 273 aa
1>>>pF1KB8782 273 - 273 aa - 273 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.0713+/-0.000605; mu= -37.2057+/- 0.035
mean_var=729.4664+/-159.391, 0's: 0 Z-trim(115.2): 1404 B-trim: 438 in 1/55
Lambda= 0.047487
statistics sampled from 23635 (25529) to 23635 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.299), width: 16
Scan time: 7.070
The best scores are: opt bits E(85289)
NP_114426 (OMIM: 610712) testis-specific serine/th ( 273) 1840 141.6 1.5e-33
NP_443073 (OMIM: 607660) testis-specific serine/th ( 268) 820 71.7 1.6e-12
NP_443732 (OMIM: 610710) testis-specific serine/th ( 358) 818 71.7 2.2e-12
NP_114417 (OMIM: 610709) testis-specific serine/th ( 367) 817 71.6 2.4e-12
NP_113605 (OMIM: 606495) MAP/microtubule affinity- ( 688) 613 57.9 6e-08
NP_001186796 (OMIM: 606495) MAP/microtubule affini ( 752) 613 57.9 6.4e-08
XP_011527776 (OMIM: 605705,616341) PREDICTED: seri ( 734) 610 57.7 7.2e-08
NP_775490 (OMIM: 605705,616341) serine/threonine-p ( 783) 610 57.7 7.6e-08
NP_001273055 (OMIM: 606511) serine/threonine-prote ( 780) 599 57.0 1.3e-07
XP_005273191 (OMIM: 606511) PREDICTED: serine/thre ( 781) 599 57.0 1.3e-07
XP_011507863 (OMIM: 606511) PREDICTED: serine/thre ( 788) 599 57.0 1.3e-07
NP_061120 (OMIM: 606511) serine/threonine-protein ( 795) 599 57.0 1.3e-07
NP_001273053 (OMIM: 606511) serine/threonine-prote ( 796) 599 57.0 1.3e-07
XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtu ( 643) 594 56.6 1.4e-07
XP_016876782 (OMIM: 602678) PREDICTED: MAP/microtu ( 708) 594 56.6 1.5e-07
NP_001122392 (OMIM: 602678) MAP/microtubule affini ( 713) 594 56.6 1.5e-07
XP_016876781 (OMIM: 602678) PREDICTED: MAP/microtu ( 722) 594 56.6 1.5e-07
XP_016876780 (OMIM: 602678) PREDICTED: MAP/microtu ( 728) 594 56.6 1.5e-07
NP_002367 (OMIM: 602678) MAP/microtubule affinity- ( 729) 594 56.6 1.5e-07
XP_005267699 (OMIM: 602678) PREDICTED: MAP/microtu ( 737) 594 56.6 1.6e-07
XP_005267698 (OMIM: 602678) PREDICTED: MAP/microtu ( 738) 594 56.6 1.6e-07
XP_006720209 (OMIM: 602678) PREDICTED: MAP/microtu ( 739) 594 56.6 1.6e-07
NP_001122391 (OMIM: 602678) MAP/microtubule affini ( 744) 594 56.6 1.6e-07
NP_001122390 (OMIM: 602678) MAP/microtubule affini ( 753) 594 56.6 1.6e-07
NP_001156769 (OMIM: 600526) serine/threonine-prote ( 709) 591 56.4 1.7e-07
NP_001156768 (OMIM: 600526) serine/threonine-prote ( 719) 591 56.4 1.8e-07
NP_004945 (OMIM: 600526) serine/threonine-protein ( 724) 591 56.4 1.8e-07
XP_011543100 (OMIM: 600526) PREDICTED: serine/thre ( 729) 591 56.4 1.8e-07
XP_016872800 (OMIM: 600526) PREDICTED: serine/thre ( 738) 591 56.4 1.8e-07
XP_011543099 (OMIM: 600526) PREDICTED: serine/thre ( 739) 591 56.4 1.8e-07
XP_011543098 (OMIM: 600526) PREDICTED: serine/thre ( 744) 591 56.4 1.8e-07
NP_059672 (OMIM: 600526) serine/threonine-protein ( 745) 591 56.4 1.8e-07
XP_011543097 (OMIM: 600526) PREDICTED: serine/thre ( 745) 591 56.4 1.8e-07
XP_011543096 (OMIM: 600526) PREDICTED: serine/thre ( 753) 591 56.4 1.8e-07
XP_016872799 (OMIM: 600526) PREDICTED: serine/thre ( 763) 591 56.4 1.8e-07
XP_011543095 (OMIM: 600526) PREDICTED: serine/thre ( 784) 591 56.4 1.9e-07
NP_001034558 (OMIM: 600526) serine/threonine-prote ( 788) 591 56.4 1.9e-07
XP_011543094 (OMIM: 600526) PREDICTED: serine/thre ( 793) 591 56.4 1.9e-07
XP_011543093 (OMIM: 600526) PREDICTED: serine/thre ( 798) 591 56.4 1.9e-07
XP_011543092 (OMIM: 600526) PREDICTED: serine/thre ( 799) 591 56.4 1.9e-07
XP_011543091 (OMIM: 600526) PREDICTED: serine/thre ( 808) 591 56.4 1.9e-07
XP_011541028 (OMIM: 614776) PREDICTED: serine/thre ( 660) 569 54.9 4.7e-07
XP_016872913 (OMIM: 614776) PREDICTED: serine/thre (1213) 569 55.1 7.3e-07
NP_001268678 (OMIM: 614776) serine/threonine-prote (1261) 569 55.1 7.5e-07
XP_005271541 (OMIM: 614776) PREDICTED: serine/thre (1261) 569 55.1 7.5e-07
XP_011541024 (OMIM: 614776) PREDICTED: serine/thre (1309) 569 55.1 7.7e-07
XP_005271539 (OMIM: 614776) PREDICTED: serine/thre (1321) 569 55.1 7.7e-07
NP_079440 (OMIM: 614776) serine/threonine-protein (1321) 569 55.1 7.7e-07
XP_006723370 (OMIM: 606495) PREDICTED: MAP/microtu ( 685) 559 54.2 7.8e-07
XP_005271538 (OMIM: 614776) PREDICTED: serine/thre (1369) 569 55.2 7.9e-07
>>NP_114426 (OMIM: 610712) testis-specific serine/threon (273 aa)
initn: 1840 init1: 1840 opt: 1840 Z-score: 723.1 bits: 141.6 E(85289): 1.5e-33
Smith-Waterman score: 1840; 100.0% identity (100.0% similar) in 273 aa overlap (1-273:1-273)
10 20 30 40 50 60
pF1KB8 MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAATDLLQAVQRNGRIPGVQARDLFAQIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 LSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAATDLLQAVQRNGRIPGVQARDLFAQIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLSTTYCGSAAYASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 GAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLSTTYCGSAAYASP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 EVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERC
190 200 210 220 230 240
250 260 270
pF1KB8 KALIAELLQFSPSARPSAGQVARNCWLRAGDSG
:::::::::::::::::::::::::::::::::
NP_114 KALIAELLQFSPSARPSAGQVARNCWLRAGDSG
250 260 270
>>NP_443073 (OMIM: 607660) testis-specific serine/threon (268 aa)
initn: 551 init1: 551 opt: 820 Z-score: 345.6 bits: 71.7 E(85289): 1.6e-12
Smith-Waterman score: 820; 49.2% identity (75.2% similar) in 266 aa overlap (4-267:3-265)
10 20 30 40 50 60
pF1KB8 MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRE
: :::. ::.::.:::::.::::: : :::.. :::::.:. .: .:...:::::
NP_443 MEDFLLSN-GYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRE
10 20 30 40 50
70 80 90 100 110
pF1KB8 LSILRGVRHPHIVHVFEFIEVCNGKLYIVME-AAATDLLQAVQRNGRIPGVQARDLFAQI
:.:.: . : .:..:.:..: .::. .::: : . :... : .: .: .:. :: :.
NP_443 LQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 AGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGR-QAHGYPDLSTTYCGSAAYA
. :.:: : ..::::::::.::. .:::::::.. ... .:: :.:::.:::
NP_443 VEAIRYCHGCGVAHRDLKCENALLQG--FNLKLTDFGFAKVLPKSHRELSQTFCGSTAYA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 SPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSE
.:::: :::.: :: ::::::::::::. . .::::.:: . .:..:: .: : .:
NP_443 APEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISA
180 190 200 210 220 230
240 250 260 270
pF1KB8 RCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG
:. :. .::. . ::: .:. . ::
NP_443 DCQDLLKRLLEPDMILRPSIEEVSWHPWLAST
240 250 260
>>NP_443732 (OMIM: 610710) testis-specific serine/threon (358 aa)
initn: 765 init1: 292 opt: 818 Z-score: 343.2 bits: 71.7 E(85289): 2.2e-12
Smith-Waterman score: 818; 46.4% identity (74.5% similar) in 274 aa overlap (1-268:1-273)
10 20 30 40 50 60
pF1KB8 MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRE
:. .: . :: .: ..:.:::.::: : :.. : .::.:..::...: :::..:::::
NP_443 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPRE
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 LSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQI
..:: : : :....:..:. .:..::.:: .. :::. .. .: . :: .: :.
NP_443 MDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 AGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFG----RQAHGYPDLSTTYCGSA
..::.: :: .:::::::::.::. : .::.::::. :...: :: :.::::
NP_443 SSAVKYCHDLDIVHRDLKCENLLLDKDFN-IKLSDFGFSKRCLRDSNGRIILSKTFCGSA
130 140 150 160 170
180 190 200 210 220 230
pF1KB8 AYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRG-VLYPEGL
:::.:::: .:::.:: ::.::.::.::.:: : ::.::::: . : ::. : .:..
NP_443 AYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSK
180 190 200 210 220 230
240 250 260 270
pF1KB8 ELSERCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG
.:. .:: :: ..:: . : : .. . ::.
NP_443 NLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKL
240 250 260 270 280 290
NP_443 DTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST
300 310 320 330 340 350
>>NP_114417 (OMIM: 610709) testis-specific serine/threon (367 aa)
initn: 771 init1: 302 opt: 817 Z-score: 342.7 bits: 71.6 E(85289): 2.4e-12
Smith-Waterman score: 817; 46.2% identity (72.0% similar) in 279 aa overlap (1-273:1-278)
10 20 30 40 50 60
pF1KB8 MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRE
:. .:.. :: :: ..:::::.::: : :.. : .::::..::..:: ::..::::::
NP_114 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPRE
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 LSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQI
. :: . : :....:..:. .::.::::: :. :::. .. : . .:: : :.
NP_114 IEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 AGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFG----RQAHGYPDLSTTYCGSA
. :..: :: .:::::::.:.::. : .::.::.:. :. : :: :.:::
NP_114 SLAIKYCHDLDVVHRDLKCDNLLLDKDFN-IKLSDFSFSKRCLRDDSGRMALSKTFCGSP
130 140 150 160 170
180 190 200 210 220 230
pF1KB8 AYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRG-VLYPEGL
:::.:::: ::::.:: ::.::.::.::.:: : ::.:::.: . : ::. : .:..
NP_114 AYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSK
180 190 200 210 220 230
240 250 260 270
pF1KB8 ELSERCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG
.:. .:: :: ..:: . . : .. .::.. :
NP_114 HLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWT
240 250 260 270 280 290
NP_114 PEPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQ
300 310 320 330 340 350
>>NP_113605 (OMIM: 606495) MAP/microtubule affinity-regu (688 aa)
initn: 535 init1: 219 opt: 613 Z-score: 263.7 bits: 57.9 E(85289): 6e-08
Smith-Waterman score: 613; 38.8% identity (69.2% similar) in 263 aa overlap (12-273:59-316)
10 20 30 40
pF1KB8 MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIK
:.: ::::.:...:::.: ::::
NP_113 KGPSWSSRSLGARCRNSIASCPEEQPHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIK
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB8 VVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVME-AAATDLLQA
..:. . :. ..:.. ::. :..:. ::.::..:: ::. . ::.::: :.: ....
NP_113 IIDKTQLNPSSLQKLF-REVRIMKGLNHPNIVKLFEVIET-EKTLYLVMEYASAGEVFDY
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB8 VQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQ
. .::. .:: : ::..::.: :....:::::: ::.::. : .:..::::. .
NP_113 LVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDA-EANIKIADFGFSNE
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB8 AHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGL
:.: .::: ::.::.. : :: . :.::.::.::..:.: .::: .. :
NP_113 FTLGSKLDT-FCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKEL
210 220 230 240 250 260
230 240 250 260 270
pF1KB8 PRRQKRGVLYPEGLELSERCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG
.: :: : . .: :.... ..: ..:. : . :. .. :. : :
NP_113 RERVLRGK-YRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIGYEGEELKPYT
270 280 290 300 310 320
NP_113 EPEEDFGDTKRIEVMVGMGYTREEIKESLTSQKYNEVTATYLLLGRKTEEGGDRGAPGLA
330 340 350 360 370 380
>>NP_001186796 (OMIM: 606495) MAP/microtubule affinity-r (752 aa)
initn: 564 init1: 219 opt: 613 Z-score: 263.2 bits: 57.9 E(85289): 6.4e-08
Smith-Waterman score: 613; 38.8% identity (69.2% similar) in 263 aa overlap (12-273:59-316)
10 20 30 40
pF1KB8 MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIK
:.: ::::.:...:::.: ::::
NP_001 KGPSWSSRSLGARCRNSIASCPEEQPHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIK
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB8 VVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVME-AAATDLLQA
..:. . :. ..:.. ::. :..:. ::.::..:: ::. . ::.::: :.: ....
NP_001 IIDKTQLNPSSLQKLF-REVRIMKGLNHPNIVKLFEVIET-EKTLYLVMEYASAGEVFDY
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB8 VQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQ
. .::. .:: : ::..::.: :....:::::: ::.::. : .:..::::. .
NP_001 LVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDA-EANIKIADFGFSNE
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB8 AHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGL
:.: .::: ::.::.. : :: . :.::.::.::..:.: .::: .. :
NP_001 FTLGSKLDT-FCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKEL
210 220 230 240 250 260
230 240 250 260 270
pF1KB8 PRRQKRGVLYPEGLELSERCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG
.: :: : . .: :.... ..: ..:. : . :. .. :. : :
NP_001 RERVLRGK-YRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIGYEGEELKPYT
270 280 290 300 310 320
NP_001 EPEEDFGDTKRIEVMVGMGYTREEIKESLTSQKYNEVTATYLLLGRKTEEGGDRGAPGLA
330 340 350 360 370 380
>>XP_011527776 (OMIM: 605705,616341) PREDICTED: serine/t (734 aa)
initn: 480 init1: 220 opt: 610 Z-score: 262.2 bits: 57.7 E(85289): 7.2e-08
Smith-Waterman score: 610; 39.0% identity (68.7% similar) in 259 aa overlap (12-269:27-280)
10 20 30 40
pF1KB8 MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDR
: . ::.:.:... ::.: . : ::::..:.
XP_011 MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 RRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRN
: . ..:. ::..... . ::::..... .:. . :::: : : . .... . :
XP_011 TRLDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMETKD-MLYIVTEFAKNGEMFDYLTSN
70 80 90 100 110
110 120 130 140 150 160
pF1KB8 GRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGY
:.. .:: : :: .::.: ::::.:::::: ::.::. . .::.::::: ..
XP_011 GHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMD-IKLADFGFGNFYKSG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 PDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQ
::: .::: ::.:::. : :. . :.::.::::::.: : .::: .. : .:
XP_011 EPLST-WCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRV
180 190 200 210 220 230
230 240 250 260 270
pF1KB8 KRGVLYPEGLELSERCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG
.: . . .:. :..:: ..: .:. : . .:. .. :.::
XP_011 LEGRFRIP-FFMSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEPCLPGPACPAFSAH
240 250 260 270 280 290
XP_011 SYTSNLGDYDEQALGIMQTLGVDRQRTVEVPQEGLSTDPFRPALLCPQPQTLVQSVLQAE
300 310 320 330 340 350
>>NP_775490 (OMIM: 605705,616341) serine/threonine-prote (783 aa)
initn: 480 init1: 220 opt: 610 Z-score: 261.9 bits: 57.7 E(85289): 7.6e-08
Smith-Waterman score: 610; 39.0% identity (68.7% similar) in 259 aa overlap (12-269:27-280)
10 20 30 40
pF1KB8 MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDR
: . ::.:.:... ::.: . : ::::..:.
NP_775 MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 RRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRN
: . ..:. ::..... . ::::..... .:. . :::: : : . .... . :
NP_775 TRLDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMETKD-MLYIVTEFAKNGEMFDYLTSN
70 80 90 100 110
110 120 130 140 150 160
pF1KB8 GRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGY
:.. .:: : :: .::.: ::::.:::::: ::.::. . .::.::::: ..
NP_775 GHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMD-IKLADFGFGNFYKSG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 PDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQ
::: .::: ::.:::. : :. . :.::.::::::.: : .::: .. : .:
NP_775 EPLST-WCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRV
180 190 200 210 220 230
230 240 250 260 270
pF1KB8 KRGVLYPEGLELSERCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG
.: . . .:. :..:: ..: .:. : . .:. .. :.::
NP_775 LEGRFRIP-FFMSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEPCLPGPACPAFSAH
240 250 260 270 280 290
NP_775 SYTSNLGDYDEQALGIMQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNAQCAR
300 310 320 330 340 350
>>NP_001273055 (OMIM: 606511) serine/threonine-protein k (780 aa)
initn: 520 init1: 209 opt: 599 Z-score: 257.8 bits: 57.0 E(85289): 1.3e-07
Smith-Waterman score: 599; 38.8% identity (68.8% similar) in 260 aa overlap (12-270:60-314)
10 20 30 40
pF1KB8 MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIK
:.: .:::.:...:::.: ::.:
NP_001 QPTKSSSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVK
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB8 VVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVME-AAATDLLQA
..:. . : ..:.. ::. :.. . ::.::..:: ::. . ::.::: :.. ....
NP_001 IIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET-EKTLYLVMEYASGGEVFDY
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB8 VQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQ
. .::. .:: : ::..::.: :....:::::: ::.::. : .:..::::. .
NP_001 LVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMN-IKIADFGFSNE
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB8 AHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGL
:.: .::: ::.::.. : :: . ::::.::.::..:.: .::: ... :
NP_001 FTVGNKLDT-FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKEL
210 220 230 240 250 260
230 240 250 260 270
pF1KB8 PRRQKRGVLYPEGLELSERCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG
.: :: : . .: :. :. .:: ..: : : :. .. :. .:
NP_001 RERVLRGK-YRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPYT
270 280 290 300 310 320
NP_001 EPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYILLGRKPPEFEGGESLSSG
330 340 350 360 370 380
>>XP_005273191 (OMIM: 606511) PREDICTED: serine/threonin (781 aa)
initn: 520 init1: 209 opt: 599 Z-score: 257.8 bits: 57.0 E(85289): 1.3e-07
Smith-Waterman score: 599; 38.8% identity (68.8% similar) in 260 aa overlap (12-270:60-314)
10 20 30 40
pF1KB8 MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIK
:.: .:::.:...:::.: ::.:
XP_005 QPTKSSSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVK
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB8 VVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVME-AAATDLLQA
..:. . : ..:.. ::. :.. . ::.::..:: ::. . ::.::: :.. ....
XP_005 IIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET-EKTLYLVMEYASGGEVFDY
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB8 VQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQ
. .::. .:: : ::..::.: :....:::::: ::.::. : .:..::::. .
XP_005 LVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMN-IKIADFGFSNE
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB8 AHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGL
:.: .::: ::.::.. : :: . ::::.::.::..:.: .::: ... :
XP_005 FTVGNKLDT-FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKEL
210 220 230 240 250 260
230 240 250 260 270
pF1KB8 PRRQKRGVLYPEGLELSERCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG
.: :: : . .: :. :. .:: ..: : : :. .. :. .:
XP_005 RERVLRGK-YRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPYT
270 280 290 300 310 320
XP_005 EPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYILLGRKPPEFEGGESLSSG
330 340 350 360 370 380
273 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:33:56 2016 done: Fri Nov 4 15:33:57 2016
Total Scan time: 7.070 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]